KEGG   PATHWAY: slx00630
Entry
slx00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces lavendulae subsp. lavendulae
Class
Metabolism; Carbohydrate metabolism
Pathway map
slx00630  Glyoxylate and dicarboxylate metabolism
slx00630

Module
slx_M00012  Glyoxylate cycle [PATH:slx00630]
slx_M00621  Glycine cleavage system [PATH:slx00630]
slx_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:slx00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces lavendulae subsp. lavendulae [GN:slx]
Gene
SLAV_04405  kdgA; KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
SLAV_06750  [KO:K00104] [EC:1.1.99.14]
SLAV_07575  fadA1; Putative acyltransferase [KO:K00626] [EC:2.3.1.9]
SLAV_08025  mutB1; Methylmalonyl-CoA mutase large subunit [KO:K14447] [EC:5.4.99.63]
SLAV_08080  garK; Glycerate 2-kinase [KO:K00865] [EC:2.7.1.165]
SLAV_08705  aceB1; Malate synthase [KO:K01638] [EC:2.3.3.9]
SLAV_08775  hyi; Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
SLAV_08780  garR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
SLAV_08785  bca1; Bromoperoxidase-catalase [KO:K03781] [EC:1.11.1.6]
SLAV_08795  gcl; Glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
SLAV_09270  [KO:K01846] [EC:5.4.99.1]
SLAV_09275  mutE; Methylaspartate mutase E chain [KO:K19268] [EC:5.4.99.1]
SLAV_10035  acnA; Aconitate hydratase [KO:K27802]
SLAV_10320  mutA; Methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
SLAV_10325  mutB2; Methylmalonyl-CoA mutase large subunit [KO:K01847] [EC:5.4.99.2]
SLAV_10725  citA1; Citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
SLAV_10730  citZ; Citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
SLAV_12400  gcvT; Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
SLAV_12405  gcvH; Glycine cleavage system H protein [KO:K02437]
SLAV_12410  glyA1; Serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
SLAV_12790  [KO:K00626] [EC:2.3.1.9]
SLAV_12795  [KO:K05606] [EC:5.1.99.1]
SLAV_12945  glyA2; Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SLAV_13205  kgd; Multifunctional 2-oxoglutarate metabolism enzyme [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
SLAV_13560  bca2; Bromoperoxidase-catalase [KO:K03781] [EC:1.11.1.6]
SLAV_14910  accD3; putative propionyl-CoA carboxylase beta chain 5 [KO:K27094]
SLAV_14915  [KO:K27095]
SLAV_14935  accC; Biotin carboxylase [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
SLAV_15165  scpA2; Methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
SLAV_15290  glyA3; Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SLAV_15340  mdh; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
SLAV_17005  purU; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
SLAV_17155  citA2; Citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
SLAV_17370  [KO:K01091] [EC:3.1.3.18]
SLAV_20670  acsA1; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
SLAV_21875  lysN2; 2-aminoadipate transaminase [KO:K05825] [EC:2.6.1.-]
SLAV_22655  thlA; Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SLAV_23370  [KO:K00104] [EC:1.1.99.14]
SLAV_24055  gltA2; Citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
SLAV_26020  glnA1; putative glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
SLAV_26170  glnII; Glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
SLAV_26260  glnA2; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SLAV_26305  pdhD; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
SLAV_29440  glnA3; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
SLAV_30875  gcvP; Glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
SLAV_31420  [KO:K00127]
SLAV_32990  [KO:K00626] [EC:2.3.1.9]
SLAV_34060  katE; Catalase HPII [KO:K03781] [EC:1.11.1.6]
SLAV_34415  icl; Isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
SLAV_34420  aceB2; Malate synthase [KO:K01638] [EC:2.3.3.9]
SLAV_35195  lpdC; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00049  L-Aspartate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C05840  Iminoaspartate
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C19838  D-erythro-3-Hydroxyaspartate
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
slx00010  Glycolysis / Gluconeogenesis
slx00020  Citrate cycle (TCA cycle)
slx00030  Pentose phosphate pathway
slx00053  Ascorbate and aldarate metabolism
slx00071  Fatty acid degradation
slx00230  Purine metabolism
slx00250  Alanine, aspartate and glutamate metabolism
slx00260  Glycine, serine and threonine metabolism
slx00270  Cysteine and methionine metabolism
slx00620  Pyruvate metabolism
slx00710  Carbon fixation by Calvin cycle
slx00750  Vitamin B6 metabolism
slx00910  Nitrogen metabolism
KO pathway
ko00630   

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