KEGG   PATHWAY: sme00670
Entry
sme00670                    Pathway                                
Name
One carbon pool by folate - Sinorhizobium meliloti 1021
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
sme00670  One carbon pool by folate
sme00670

Module
sme_M00126  Tetrahydrofolate biosynthesis, GTP => THF [PATH:sme00670]
sme_M00140  C1-unit interconversion, prokaryotes [PATH:sme00670]
sme_M00555  Betaine biosynthesis, choline => betaine [PATH:sme00670]
sme_M00621  Glycine cleavage system [PATH:sme00670]
Other DBs
GO: 0035999
Organism
Sinorhizobium meliloti 1021 [GN:sme]
Gene
SMa1483  [KO:K00315] [EC:1.5.8.4]
SMa1731  betB2; BetB2 betaine aldehyde dehydrogenase [KO:K00130] [EC:1.2.1.8]
SMa2135  glyA2; GlyA2 serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SMa2141  purU3; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
SMa2143  metF; 5,10-methylenetetrahydrofolate reductase [KO:K00297] [EC:1.5.1.54]
SMa2145  [KO:K00605] [EC:2.1.2.10]
SMc00093  betA; Choline dehydrogenase CHD oxidoreductase flavoprotein FAD membrane [KO:K00108] [EC:1.1.99.1]
SMc00094  betB; Betaine aldehyde dehydrogenase badh oxidoreductase NAD protein [KO:K00130] [EC:1.2.1.8]
SMc00614  purN; Probable phosphoribosylglycinamide formyltransferase gart protein [KO:K11175] [EC:2.1.2.2]
SMc01035  lpdA1; Probable dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex) protein [KO:K00382] [EC:1.8.1.4]
SMc01109  metK; Probable S-adenosylmethionine synthetase [KO:K00789] [EC:2.5.1.6]
SMc01442  folA; Probable dihydrofolate reductase [KO:K00287] [EC:1.5.1.3]
SMc01444  thyA; Probable thymidylate synthase [KO:K00560] [EC:2.1.1.45]
SMc01663  [KO:K00315] [EC:1.5.8.4]
SMc01770  glyA1; Probable serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SMc01843  metF; Probable 5,10-methylenetetrahydrofolate reductase oxidoreductase [KO:K00297] [EC:1.5.1.54]
SMc02047  gcvT; Probable aminomethyltransferase (glycine cleavage system T protein) [KO:K00605] [EC:2.1.2.10]
SMc02048  gcvH; Probable glycine cleavage system H [KO:K02437]
SMc02049  gcvP; Probable glycine dehydrogenase decarboxylating protein [KO:K00281] [EC:1.4.4.2]
SMc02487  lpdA2; Probable dihydrolipoamide dehydrogenase (E3 component of 2-oxoglutarate dehydrogenase complex) transmembrane protein [KO:K00382] [EC:1.8.1.4]
SMc02594  [KO:K01934] [EC:6.3.3.2]
SMc02604  folD1; Probable bifunctional protein : methylenetetrahydrofolate dehydrogenase; methenyltetrahydrofolate cyclohydrolase [KO:K01491] [EC:1.5.1.5 3.5.4.9]
SMc02728  fhs; Probable formate--tetrahydrofolate ligase [KO:K01938] [EC:6.3.4.3]
SMc02755  ahcY; Probable adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
SMc03059  folD2; Probable bifunctional protein : methylenetetrahydrofolate dehydrogenase; methenyltetrahydrofolate cyclohydrolase [KO:K01491] [EC:1.5.1.5 3.5.4.9]
SMc03112  metH; Probable 5-methyltetrahydrofolate--homocysteine methyltransferase (methionine synthase, vitamin-B12 dependent isozyme) protein [KO:K00548] [EC:2.1.1.13]
SMc03204  lpdA3; Probable dihydrolipoamide dehydrogenase (E3 component of branched-chain alpha-keto acid dehydrogenase complex) protein [KO:K00382] [EC:1.8.1.4]
SMc03205  purU1; Putative formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
SMc03974  [KO:K01934] [EC:6.3.3.2]
SMc04088  purH; Probable bifunctional protein, includes: phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
SMc04148  [KO:K00605] [EC:2.1.2.10]
SMc04153  [KO:K00605] [EC:2.1.2.10]
SMc04154  purU2; Probable formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
SMc04325  bmt; Betaine-homocysteine methyltransferase [KO:K00548] [EC:2.1.1.13]
SMc04340  [KO:K00297] [EC:1.5.1.54]
SMc04342  [KO:K00548] [EC:2.1.1.13]
Compound
C00002  ATP
C00019  S-Adenosyl-L-methionine
C00021  S-Adenosyl-L-homocysteine
C00037  Glycine
C00065  L-Serine
C00073  L-Methionine
C00097  L-Cysteine
C00101  Tetrahydrofolate
C00114  Choline
C00143  5,10-Methylenetetrahydrofolate
C00155  L-Homocysteine
C00212  Adenosine
C00213  Sarcosine
C00234  10-Formyltetrahydrofolate
C00364  dTMP
C00365  dUMP
C00415  Dihydrofolate
C00440  5-Methyltetrahydrofolate
C00445  5,10-Methenyltetrahydrofolate
C00504  Folate
C00576  Betaine aldehyde
C00664  5-Formiminotetrahydrofolate
C00719  Betaine
C01026  N,N-Dimethylglycine
C02291  L-Cystathionine
C03479  Folinic acid
Related
pathway
sme00260  Glycine, serine and threonine metabolism
sme00270  Cysteine and methionine metabolism
sme00790  Folate biosynthesis
KO pathway
ko00670   

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