KEGG   PATHWAY: spu00830
Entry
spu00830                    Pathway                                
Name
Retinol metabolism - Strongylocentrotus purpuratus (purple sea urchin)
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
spu00830  Retinol metabolism
spu00830

Other DBs
GO: 0006776
Organism
Strongylocentrotus purpuratus (purple sea urchin) [GN:spu]
Gene
591892  beta,beta-carotene 15,15'-dioxygenase [KO:K00515] [EC:1.13.11.63]
579220  alcohol dehydrogenase class-3 isoform X1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
764565  dehydrogenase/reductase SDR family member 4 [KO:K11147] [EC:1.1.-.-]
592953  retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
115922989  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
592646  retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
591131  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
105445111  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
592630  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
765012  retinol dehydrogenase 8 isoform X1 [KO:K11150] [EC:1.1.1.-]
575564  retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
100891188  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
100888213  retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
591857  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
585486  retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
574922  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
100891757  retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
100894059  retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
105436638  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
582508  retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
115918734  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
762727  retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
577528  retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
100893807  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
115925475  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
100888308  retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
115918852  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
115918854  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
586003  retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
574716  retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
577205  retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
577804  retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
590337  retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
589814  retinol dehydrogenase 12 [KO:K11153] [EC:1.1.1.300]
764557  retinol dehydrogenase 11 [KO:K11153] [EC:1.1.1.300]
585277  short-chain dehydrogenase TIC 32, chloroplastic [KO:K11153] [EC:1.1.1.300]
115918582  dehydrogenase/reductase SDR family member on chromosome X-like [KO:K11153] [EC:1.1.1.300]
115923371  retinol dehydrogenase 12-like [KO:K11153] [EC:1.1.1.300]
764683  retinol dehydrogenase 12 [KO:K11153] [EC:1.1.1.300]
763133  retinol dehydrogenase 12 [KO:K11153] [EC:1.1.1.300]
763589  retinol dehydrogenase 12 [KO:K11153] [EC:1.1.1.300]
115927508  retinol dehydrogenase 12-like [KO:K11153] [EC:1.1.1.300]
764462  retinol dehydrogenase 12 [KO:K11153] [EC:1.1.1.300]
578695  retinol dehydrogenase 12 [KO:K11153] [EC:1.1.1.300]
587795  retinol dehydrogenase 12-like isoform X1 [KO:K11153] [EC:1.1.1.300]
583677  retinol dehydrogenase 13 [KO:K11153] [EC:1.1.1.300]
593999  retinol dehydrogenase 13 [KO:K11161] [EC:1.1.1.300]
575923  retinol dehydrogenase 7 [KO:K11154] [EC:1.1.1.-]
115918616  retinol dehydrogenase 7-like [KO:K11154] [EC:1.1.1.-]
581999  epidermal retinol dehydrogenase 2 isoform X2 [KO:K15734] [EC:1.1.1.105]
576258  retinol dehydrogenase 10-B [KO:K15734] [EC:1.1.1.105]
115925479  retinol dehydrogenase 10-B-like [KO:K15734] [EC:1.1.1.105]
584929  epidermal retinol dehydrogenase 2 [KO:K15734] [EC:1.1.1.105]
575003  diacylglycerol O-acyltransferase 1 [KO:K11155] [EC:2.3.1.20 2.3.1.75 2.3.1.76]
763231  patatin-like phospholipase domain-containing protein 4 [KO:K11157] [EC:3.1.1.-]
763218  patatin-like phospholipase domain-containing protein 4 [KO:K11157] [EC:3.1.1.-]
115925507  uncharacterized protein LOC115925507 [KO:K11157] [EC:3.1.1.-]
115925515  uncharacterized protein LOC115925515 [KO:K11157] [EC:3.1.1.-]
578573  UDP-glucuronosyltransferase 1-2 [KO:K00699] [EC:2.4.1.17]
592958  UDP-glucuronosyltransferase 2C1 isoform X1 [KO:K00699] [EC:2.4.1.17]
593427  UDP-glucuronosyltransferase 1-6 [KO:K00699] [EC:2.4.1.17]
592078  UDP-glucuronosyltransferase 1-6 [KO:K00699] [EC:2.4.1.17]
578628  UDP-glucuronosyltransferase 1-8 [KO:K00699] [EC:2.4.1.17]
764059  UDP-glucuronosyltransferase 2C1 isoform X1 [KO:K00699] [EC:2.4.1.17]
755955  UDP-glucuronosyltransferase 2B18-like [KO:K00699] [EC:2.4.1.17]
115922271  UDP-glucuronosyltransferase 2C1-like [KO:K00699] [EC:2.4.1.17]
580284  UDP-glucuronosyltransferase 2C1 [KO:K00699] [EC:2.4.1.17]
578924  UDP-glucuronosyltransferase 2C1-like [KO:K00699] [EC:2.4.1.17]
589187  UDP-glucuronosyltransferase 2C1 isoform X1 [KO:K00699] [EC:2.4.1.17]
582057  UDP-glucuronosyltransferase 1-2-like [KO:K00699] [EC:2.4.1.17]
115920758  UDP-glucuronosyltransferase 1-7C-like [KO:K00699] [EC:2.4.1.17]
581862  UDP-glucuronosyltransferase 2A1-like [KO:K00699] [EC:2.4.1.17]
100893272  UDP-glucuronosyltransferase 2A1 [KO:K00699] [EC:2.4.1.17]
592931  UDP-glucuronosyltransferase 2C1 [KO:K00699] [EC:2.4.1.17]
582456  UDP-glucuronosyltransferase 2C1-like [KO:K00699] [EC:2.4.1.17]
100892570  UDP-glucuronosyltransferase 2C1 [KO:K00699] [EC:2.4.1.17]
586865  UDP-glucuronosyltransferase 2C1 isoform X2 [KO:K00699] [EC:2.4.1.17]
115917912  UDP-glucuronosyltransferase 2C1-like [KO:K00699] [EC:2.4.1.17]
100888948  UDP-glucuronosyltransferase 2C1-like [KO:K00699] [EC:2.4.1.17]
575220  UDP-glucuronosyltransferase [KO:K00699] [EC:2.4.1.17]
100893671  UDP-glucuronosyltransferase 2C1-like [KO:K00699] [EC:2.4.1.17]
105444861  UDP-glucuronosyltransferase 1-2-like [KO:K00699] [EC:2.4.1.17]
100893231  UDP-glucuronosyltransferase 2C1 [KO:K00699] [EC:2.4.1.17]
115918426  UDP-glucuronosyltransferase 2B33-like [KO:K00699] [EC:2.4.1.17]
581792  UDP-glucuronosyltransferase 2C1 [KO:K00699] [EC:2.4.1.17]
115919873  UDP-glucuronosyltransferase 1-4-like [KO:K00699] [EC:2.4.1.17]
581841  UDP-glucuronosyltransferase 2C1-like [KO:K00699] [EC:2.4.1.17]
580846  UDP-glucuronosyltransferase 2C1 [KO:K00699] [EC:2.4.1.17]
592305  UDP-glucuronosyltransferase 1-2-like [KO:K00699] [EC:2.4.1.17]
582989  UDP-glucuronosyltransferase 2A1 [KO:K00699] [EC:2.4.1.17]
582390  UDP-glucuronosyltransferase 1-6-like [KO:K00699] [EC:2.4.1.17]
591823  UDP-glucuronosyltransferase 2B31 [KO:K00699] [EC:2.4.1.17]
105439455  UDP-glucuronosyltransferase 1-2 [KO:K00699] [EC:2.4.1.17]
100889303  UDP-glucuronosyltransferase 2C1 [KO:K00699] [EC:2.4.1.17]
578623  UDP-glucuronosyltransferase 2B1 isoform X3 [KO:K00699] [EC:2.4.1.17]
115924776  UDP-glucuronosyltransferase 2B33-like [KO:K00699] [EC:2.4.1.17]
593640  UDP-glucuronosyltransferase 2C1 [KO:K00699] [EC:2.4.1.17]
580789  UDP-glucuronosyltransferase 1-2 [KO:K00699] [EC:2.4.1.17]
115925289  UDP-glucuronosyltransferase 2B1-like [KO:K00699] [EC:2.4.1.17]
582820  UDP-glucuronosyltransferase 2C1-like [KO:K00699] [EC:2.4.1.17]
115926435  UDP-glucuronosyltransferase 2B17-like [KO:K00699] [EC:2.4.1.17]
105444322  UDP-glucuronosyltransferase 2B31-like [KO:K00699] [EC:2.4.1.17]
115926442  UDP-glucuronosyltransferase 2C1-like [KO:K00699] [EC:2.4.1.17]
115926443  UDP-glucuronosyltransferase 2B7-like [KO:K00699] [EC:2.4.1.17]
115926445  UDP-glucuronosyltransferase 2B7-like [KO:K00699] [EC:2.4.1.17]
115926714  UDP-glucuronosyltransferase 1-1-like [KO:K00699] [EC:2.4.1.17]
584438  UDP-glucuronosyltransferase 2B17 [KO:K00699] [EC:2.4.1.17]
575738  UDP-glucuronosyltransferase 2B1 [KO:K00699] [EC:2.4.1.17]
105443756  UDP-glucuronosyltransferase 2C1-like [KO:K00699] [EC:2.4.1.17]
581741  UDP-glucuronosyltransferase 2C1 [KO:K00699] [EC:2.4.1.17]
581857  UDP-glucuronosyltransferase 2B1 [KO:K00699] [EC:2.4.1.17]
585947  UDP-glucuronosyltransferase 2C1-like [KO:K00699] [EC:2.4.1.17]
100892045  UDP-glucuronosyltransferase 1-2 [KO:K00699] [EC:2.4.1.17]
589827  UDP-glucuronosyltransferase 2A1 [KO:K00699] [EC:2.4.1.17]
591053  UDP-glucuronosyltransferase 1-2 [KO:K00699] [EC:2.4.1.17]
586804  UDP-glucuronosyltransferase 2B1 [KO:K00699] [EC:2.4.1.17]
115928711  UDP-glucuronosyltransferase 2B33-like [KO:K00699] [EC:2.4.1.17]
100888011  UDP-glucuronosyltransferase 2B1 [KO:K00699] [EC:2.4.1.17]
115918951  UDP-glucuronosyltransferase 2B1-like [KO:K00699] [EC:2.4.1.17]
581285  all-trans-retinol 13,14-reductase [KO:K09516] [EC:1.3.99.23]
115919953  all-trans-retinol 13,14-reductase-like [KO:K09516] [EC:1.3.99.23]
Compound
C00376  Retinal
C00473  Retinol
C00777  Retinoate
C00778  Rhodopsin
C00899  11-cis-Retinol
C02075  Retinyl ester
C02094  beta-Carotene
C02110  11-cis-Retinal
C02588  Retinyl palmitate
C03455  11-cis-Retinyl palmitate
C05914  Bathorhodopsin
C05915  Lumirhodopsin
C05916  Metarhodopsin
C05917  Iodopsin
C11061  all-trans-Retinoyl-beta-glucuronide
C15492  all-trans-13,14-Dihydroretinol
C15493  9-cis-Retinoic acid
C16677  all-trans-4-Hydroxyretinoic acid
C16678  all-trans-4-Oxoretinoic acid
C16679  all-trans-18-Hydroxyretinoic acid
C16680  all-trans-5,6-Epoxyretinoic acid
C16681  9-cis-Retinal
C16682  9-cis-Retinol
C16683  4-Oxoretinol
C21797  all-trans-3,4-Didehydroretinol
Reference
PMID:16968212
  Authors
Travis GH, Golczak M, Moise AR, Palczewski K.
  Title
Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents.
  Journal
Annu Rev Pharmacol Toxicol 47:469-512 (2007)
DOI:10.1146/annurev.pharmtox.47.120505.105225
Reference
PMID:17618621
  Authors
Muniz A, Villazana-Espinoza ET, Hatch AL, Trevino SG, Allen DM, Tsin AT.
  Title
A novel cone visual cycle in the cone-dominated retina.
  Journal
Exp Eye Res 85:175-84 (2007)
DOI:10.1016/j.exer.2007.05.003
Reference
PMID:11093772
  Authors
Marill J, Cresteil T, Lanotte M, Chabot GG.
  Title
Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.
  Journal
Mol Pharmacol 58:1341-8 (2000)
DOI:10.1124/mol.58.6.1341
Reference
PMID:17893666
  Authors
Nezzar H, Chiambaretta F, Marceau G, Blanchon L, Faye B, Dechelotte P, Rigal D, Sapin V.
  Title
Molecular and metabolic retinoid pathways in the human ocular surface.
  Journal
Mol Vis 13:1641-50 (2007)
Reference
PMID:16688755
  Authors
Blomhoff R, Blomhoff HK.
  Title
Overview of retinoid metabolism and function.
  Journal
J Neurobiol 66:606-30 (2006)
DOI:10.1002/neu.20242
Reference
PMID:16428379
  Authors
Liden M, Eriksson U.
  Title
Understanding retinol metabolism: structure and function of retinol dehydrogenases.
  Journal
J Biol Chem 281:13001-4 (2006)
DOI:10.1074/jbc.R500027200
KO pathway
ko00830   
LinkDB

DBGET integrated database retrieval system