KEGG   PATHWAY: umr03082
Entry
umr03082                    Pathway                                
Name
ATP-dependent chromatin remodeling - Ursus maritimus (polar bear)
Class
Genetic Information Processing; Chromosome
Pathway map
umr03082  ATP-dependent chromatin remodeling
umr03082

Organism
Ursus maritimus (polar bear) [GN:umr]
Gene
103656196  CHD4; chromodomain-helicase-DNA-binding protein 4 isoform X1 [KO:K11643] [EC:5.6.2.-]
103656292  BAZ2A; bromodomain adjacent to zinc finger domain protein 2A isoform X1 [KO:K15224]
103656506  EPC1; enhancer of polycomb homolog 1 isoform X1 [KO:K11322]
103656875  YEATS4; YEATS domain-containing protein 4 isoform X1 [KO:K11341]
103656928  SMARCC2; LOW QUALITY PROTEIN: SWI/SNF complex subunit SMARCC2 [KO:K11649]
103657112  RUVBL2; ruvB-like 2 [KO:K11338] [EC:5.6.2.3]
103657219  BICRA; BRD4-interacting chromatin-remodeling complex-associated protein [KO:K25612]
103657835  INO80E; INO80 complex subunit E isoform X2 [KO:K11669]
103657870  [KO:K11661] [EC:5.6.2.-]
103657931  BCL7C; B-cell CLL/lymphoma 7 protein family member C isoform X1 [KO:K25605]
103658081  SMARCA5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [KO:K11654] [EC:5.6.2.-]
103658173  UCHL5; ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform X1 [KO:K05610] [EC:3.4.19.12]
103659278  [KO:K11251]
103659453  EPC2; enhancer of polycomb homolog 2 isoform X1 [KO:K11322]
103659493  BAZ2B; bromodomain adjacent to zinc finger domain protein 2B [KO:K26167]
103659787  INO80D; INO80 complex subunit D isoform X1 [KO:K11668]
103660297  MORF4L1; mortality factor 4-like protein 1 isoform X1 [KO:K11339]
103660346  CUNH17orf49; chromatin complexes subunit BAP18 isoform X1 [KO:K23406]
103660481  [KO:K11642] [EC:5.6.2.-]
103660574  [KO:K11343]
103660583  SS18L1; calcium-responsive transactivator isoform X1 [KO:K15623]
103660744  NFRKB; nuclear factor related to kappa-B-binding protein [KO:K11671]
103660785  PHF10; PHD finger protein 10 isoform X1 [KO:K22197]
103660865  ARID1B; AT-rich interactive domain-containing protein 1B [KO:K11653]
103660947  SMARCD3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 isoform X1 [KO:K11650]
103661061  DPF1; zinc finger protein neuro-d4 isoform X1 [KO:K22198]
103661136  CDK2AP1; cyclin-dependent kinase 2-associated protein 1 [KO:K26454]
103661267  BCL7A; B-cell CLL/lymphoma 7 protein family member A isoform X1 [KO:K25605]
103661841  SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 [KO:K11651]
103663158  SS18; protein SSXT isoform X1 [KO:K15623]
103663331  SMARCA2; probable global transcription activator SNF2L2 [KO:K11647] [EC:5.6.2.-]
103663492  INO80C; INO80 complex subunit C isoform X1 [KO:K11667]
103663790  BRD8; bromodomain-containing protein 8 isoform X5 [KO:K11321]
103663804  [KO:K11251]
103664082  BICRAL; BRD4-interacting chromatin-remodeling complex-associated protein-like [KO:K25613]
103664360  MBD2; methyl-CpG-binding domain protein 2 [KO:K11590]
103665040  [KO:K11251]
103665042  [KO:K11251]
103665051  [KO:K11251]
103665056  [KO:K11251]
103665058  [KO:K11251]
103665061  [KO:K11251]
103665064  [KO:K11251]
103665068  [KO:K11251]
103665071  [KO:K11251]
103665080  [KO:K11251]
103665085  [KO:K11251]
103665099  [KO:K11251]
103665102  [KO:K11251]
103665181  [KO:K11251]
103665182  [KO:K11251]
103665205  [KO:K11251]
103665635  SMARCD2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 [KO:K11650]
103665656  BPTF; nucleosome-remodeling factor subunit BPTF isoform X5 [KO:K11728]
103665813  ACTG1; actin, cytoplasmic 2 [KO:K05692]
103666375  MEAF6; chromatin modification-related protein MEAF6 isoform X1 [KO:K11344]
103666434  RBBP4; histone-binding protein RBBP4 [KO:K10752]
103666443  HDAC1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
103666514  ARID1A; AT-rich interactive domain-containing protein 1A isoform X1 [KO:K11653]
103666519  BAZ1A; bromodomain adjacent to zinc finger domain protein 1A isoform X1 [KO:K11655]
103667519  VPS72; vacuolar protein sorting-associated protein 72 homolog [KO:K11664]
103667569  [KO:K11251]
103667570  [KO:K11251]
103667576  [KO:K11251]
103667618  SMARCA1; probable global transcription activator SNF2L1 isoform X1 [KO:K11727] [EC:5.6.2.-]
103668010  [KO:K11251]
103668153  RBBP7; histone-binding protein RBBP7 isoform X1 [KO:K11659]
103668244  YY2; transcription factor YY2 [KO:K09201]
103668414  GATAD2B; transcriptional repressor p66-beta isoform X1 [KO:K23194]
103669281  SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform X1 [KO:K11648]
103669488  RUVBL1; ruvB-like 1 [KO:K04499] [EC:5.6.2.4]
103669895  ACTR5; actin-related protein 5 isoform X1 [KO:K11672]
103670086  ACTB; actin, cytoplasmic 1 [KO:K05692]
103670100  [KO:K08874]
103670117  ACTL6B; actin-like protein 6B [KO:K11652]
103670151  BCL7B; B-cell CLL/lymphoma 7 protein family member B isoform X2 [KO:K25605]
103670198  ZNHIT1; zinc finger HIT domain-containing protein 1 isoform X1 [KO:K11663]
103670221  BAZ1B; tyrosine-protein kinase BAZ1B [KO:K11658]
103670588  CHRAC1; chromatin accessibility complex protein 1 [KO:K11656]
103670796  DMAP1; DNA methyltransferase 1-associated protein 1 [KO:K11324]
103671408  INO80B; INO80 complex subunit B isoform X2 [KO:K11666]
103671540  MTA3; metastasis-associated protein MTA3 isoform X1 [KO:K11660]
103672878  TFPT; TCF3 fusion partner isoform X1 [KO:K11670]
103672946  PHF6; PHD finger protein 6 isoform X1 [KO:K23310]
103673447  INO80; chromatin-remodeling ATPase INO80 [KO:K11665] [EC:5.6.2.-]
103673568  YY1; transcriptional repressor protein YY1 [KO:K09201]
103673915  BRD7; bromodomain-containing protein 7 isoform X1 [KO:K11723]
103674228  DPF3; zinc finger protein DPF3 [KO:K22198]
103674566  [KO:K11251]
103674733  ACTR8; actin-related protein 8 isoform X1 [KO:K11673]
103674759  PBRM1; protein polybromo-1 isoform X1 [KO:K11757]
103674863  SMARCC1; SWI/SNF complex subunit SMARCC1 [KO:K11649]
103674916  GATAD2A; transcriptional repressor p66-alpha isoform X1 [KO:K23194]
103675151  MORF4L2; mortality factor 4-like protein 2 [KO:K11342]
103675412  ARID2; AT-rich interactive domain-containing protein 2 [KO:K11765]
103675466  MCRS1; microspherule protein 1 isoform X1 [KO:K11674]
103675474  SMARCD1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [KO:K11650]
103675699  [KO:K25830]
103676119  ACTL6A; actin-like protein 6A isoform X2 [KO:K11340]
103676513  ACTR6; actin-related protein 6 isoform X2 [KO:K11662]
103676599  ING3; inhibitor of growth protein 3 [KO:K11319]
103676902  MTA1; metastasis-associated protein MTA1 isoform X1 [KO:K11660]
103676974  HDAC2; histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
103677774  [KO:K11251]
103677932  [KO:K11251]
103678136  RSF1; remodeling and spacing factor 1 isoform X1 [KO:K11657]
103678237  MTA2; metastasis-associated protein MTA2 [KO:K11660]
103678602  POLE3; DNA polymerase epsilon subunit 3 [KO:K02326] [EC:2.7.7.7]
103678681  SMARCA4; transcription activator BRG1 isoform X1 [KO:K11647] [EC:5.6.2.-]
103678854  [KO:K11251]
103678900  [KO:K11320] [EC:5.6.2.-]
103679242  BRD9; bromodomain-containing protein 9 isoform X1 [KO:K22184]
103679519  CDK2AP2; cyclin-dependent kinase 2-associated protein 2 isoform X1 [KO:K26455]
103679574  DPF2; zinc finger protein ubi-d4 isoform X1 [KO:K13196]
103679585  KAT5; histone acetyltransferase KAT5 [KO:K11304] [EC:2.3.1.48]
103681642  MBD3; methyl-CpG-binding domain protein 3 isoform X1 [KO:K11591]
121102918  [KO:K11251]
121103027  [KO:K11251]
121103760  [KO:K11251]
Reference
PMID:31769422
  Authors
Hasan N, Ahuja N
  Title
The Emerging Roles of ATP-Dependent Chromatin Remodeling Complexes in Pancreatic Cancer.
  Journal
Cancers (Basel) 11:cancers11121859 (2019)
DOI:10.3390/cancers11121859
Reference
PMID:32001526
  Authors
He S, Wu Z, Tian Y, Yu Z, Yu J, Wang X, Li J, Liu B, Xu Y
  Title
Structure of nucleosome-bound human BAF complex.
  Journal
Science 367:875-881 (2020)
DOI:10.1126/science.aaz9761
Reference
PMID:33941852
  Authors
Wanior M, Kramer A, Knapp S, Joerger AC
  Title
Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapy.
  Journal
Oncogene 40:3637-3654 (2021)
DOI:10.1038/s41388-021-01781-x
Reference
PMID:20493981
  Authors
Burgio G, Onorati MC, Corona DF
  Title
Chromatin remodeling regulation by small molecules and metabolites.
  Journal
Biochim Biophys Acta 1799:671-80 (2010)
DOI:10.1016/j.bbagrm.2010.05.007
KO pathway
ko03082   

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