 Polyketide synthase (PKS)
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 Modular type I PKS
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Iterative type I PKS
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Fungal nonreducing PKS (NR-PKS)
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Fungal partially reducing PKS (PR-PKS)
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Fungal highly reducing PKS (HR-PKS)
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Fungal hybrid type
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Bacterial type
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 K15314 sgcE, mdpE, ncsE, kedE, calE8, pksE; enediyne polyketide synthase
K21254 calO5; orsellinic acid synthase [EC:2.3.1.-]
K20422 ncsB; neocarzinostatin naphthoate synthase [EC:2.3.1.237]
K21221 kedU38; iterative type I polyketide synthase KedU38
K12436 pks12; mycoketide-CoA synthase [EC:2.3.1.295]
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Type II PKS
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Type III PKS
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Plant type
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Fungal type
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Bacterial type
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K16424 dpgA; 3,5-dihydroxyphenylacetyl-CoA synthase [EC:2.3.1.246]
K15431 phlD; phloroglucinol synthase [EC:2.3.1.253]
K19580 rppA; 1,3,6,8-tetrahydroxynaphthalene synthase [EC:2.3.1.233]
K16232 gcs; germicidin synthase
K16167 bpsA, srsA, pks11, pks10; alkylresorcinol/alkylpyrone synthase
K16233 pks18; alpha-pyrone synthase
K28571 arsB; alkylresorcinol synthase
K28572 arsC; alkylpyrone synthase
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PKS-NRPS hybrid
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Bacterial type (modular)
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Myxalamid hybrid PKS-NRPS
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K16416 mxaA; myxalamid-type nonribosomal peptide synthetase MxaA
K15643 mxaB; myxalamid-type polyketide synthase MxaB
K16417 mxaC; myxalamid-type polyketide synthase MxaC
K15642 mxaD; myxalamid-type polyketide synthase MxaD
K20788 mxaE; myxalamid-type polyketide synthase MxaE
K15641 mxaF; myxalamid-type polyketide synthase MxaF
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Coronatine hybrid PKS-NRPS
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K15644 cfa6; coronafacic acid polyketide synthase Cfa6
K15645 cfa7; coronafacic acid polyketide synthase Cfa7
K15646 cmaA; coronamic acid synthetase CmaA, adenylation and thiolation didomain protein [EC:6.2.1.46]
K15648 cmaD; coronamic acid synthetase CmaD, carrier protein
K15647 cmaE; coronamic acid synthetase CmaE, aminoacyltransferase [EC:2.3.2.28]
K15649 cmaT; coronamic acid synthetase CmaT, thioesterase component
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Microcystin synthetase
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K16130 mcyA; microcystin synthetase protein McyA
K16131 mcyB; microcystin synthetase protein McyB
K16132 mcyC; microcystin synthetase protein McyC
K16128 mcyD; microcystin synthetase protein McyD
K16129 mcyE; microcystin synthetase protein McyE
K16127 mcyG; microcystin synthetase protein McyG
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Epothilone synthetase
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K16394 epoA; epothilone polyketide synthase A
K16395 epoB; epothilone synthetase B
K16396 epoC; epothilone polyketide synthase C
K16397 epoD; epothilone polyketide synthase D
K16398 epoE; epothilone polyketide synthase E
K16399 epoF; epothilone polyketide synthase F
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Bleomycin synthetase
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K16113 blmIII; nonribosomal peptide synthetase protein BlmIII
K16112 blmIV; nonribosomal peptide synthetase protein BlmIV
K16107 blmV; nonribosomal peptide synthetase protein BlmV
K16106 blmVI; nonribosomal peptide synthetase protein BlmVI
K16111 blmVII; nonribosomal peptide synthetase protein BlmVII
K16110 blmVIII; nonribosomal peptide synthetase protein BlmVIII
K16109 blmIX; nonribosomal peptide synthetase protein BlmIX
K16108 blmX; nonribosomal peptide synthetase protein BlmX
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Colibactin synthetase
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K26572 clbN; colibactin biosynthesis nonribosomal peptide synthase
K26573 clbB; colibactin biosynthesis hybrid nonribosomal peptide/polyketide synthase
K26574 clbC; colibactin biosynthesis polyketide synthase
K26565 clbH; colibactin biosynthesis nonribosomal peptide synthase
K26575 clbI; colibactin biosynthesis polyketide synthase
K26578 clbJ; colibactin biosynthesis nonribosomal peptide synthase
K26577 clbK; colibactin biosynthesis hybrid nonribosomal peptide/polyketide synthase
K26576 clbO; colibactin biosynthesis polyketide synthase
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Myxothiazol hybrid PKS-NRPS
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K28573 mtaB; myxothiazol biosynthesis polyketide synthase MtaB
K28574 mtaC; myxothiazol nonribosomal peptide synthase MtaC
K28575 mtaD; myxothiazol biosynthesis hybrid nonribosomal peptide/polyketide synthetase MtaD
K28576 mtaE; myxothiazol biosynthesis polyketide synthase MtaE
K28577 mtaF; myxothiazol biosynthesis polyketide synthase MtaF
K28578 mtaG; myxothiazol nonribosomal peptide synthase MtaG
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Fungal type (trans-ER, iterative)
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Fungal type (iterative)
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Nonribosomal peptide synthetase (NRPS)
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Polyketide tailoring proteins
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Nonribosomal peptide tailoring proteins
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Polyketide Biosynthesis Proteins