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| Entry | Name | Description | Category | Pathway |
|---|---|---|---|---|
| H00323 |
Spotted fever Tick-borne rickettsioses |
Tick-borne rickettsioses are caused by gram-negative obligate intracellular bacteria belonging to the spotted fever group (SFG) of the genus Rickettsia within the family Rickettsiaceae in the order Rickettsiales ... | Bacterial infectious disease | |
| H00324 | Scrub typhus | Scrub typhus, also known as tsutsugamushi disease, is a zoonosis caused by Orientia tsutsugamushi, an obligate intracellular bacterium that is transmitted by the Leptotrombidium species mite. The disease ... | Bacterial infectious disease | |
| H00325 | Brucellosis | Brucellosis is a zoonotic disease of worldwide distribution that mainly affects persons working with domestic animals. Although many countries have eradicated Brucella abortus from cattle, Brucella melitensis ... | Bacterial infectious disease | |
| H00326 | Bartonellosis | Bartonella species are fastidious gram-negative bacilli. They are usually transmitted by hematophagous insects, such as sandflies, fleas, and lice but can also be transmitted by animal scratches and bites ... | Bacterial infectious disease | |
| H00327 | Trench fever | Trench fever is a disease caused by the facultative intracellular gram-negative bacterium Bartonella quintana. It affected several million people worldwide during the two world wars. The incidence of trench ... | Bacterial infectious disease | |
| H00328 | Anthrax | Anthrax is a zoonotic infectious disease caused by Bacillus anthracis, a Gram-positive, spore-forming bacterium belonging to the Bacillus cereus group of pathogenic Bacillus, which also includes a food ... | Bacterial infectious disease | |
| H00329 | Foodborne Bacillus cereus intoxication | Bacillus cereus is a gram-positive aerobic-to-facultatively anaerobic bacterium that causes gastrointestinal infections. The organism produces an emetic or diarrheal syndrome induced by an emetic toxin ... | Bacterial infectious disease | |
| H00330 | Methicillin-resistant Staphylococcal aureus (MRSA) infection | Methicillin-resistant Staphylococcus aureus (MRSA) is one of the major multidrug-resistant bacteria which have become endemic in the hospital environment, particularly in intensive care units (ICUs). Originally ... | Bacterial infectious disease | hsa05150 Staphylococcus aureus infection |
| H00331 | Vancomycin-resistant Staphylococcal aureus (VRSA) infection | Vancomycin-resistant Staphylococcus aureus (VRSA) represents strains of S. aureus that have ability of resistance to the glycopeptide antibiotic vancomycin. S. aureus is the most common cause of nosocomial ... | Bacterial infectious disease | hsa05150 Staphylococcus aureus infection |
| H00332 | Listeriosis | Listeriosis is a severe foodborne infection with a high case fatality rate caused by Listeria monocytogenes. High-risk groups for listeriosis include elderly and immunocompromised patients, pregnant women ... | Bacterial infectious disease | |
| H00333 | Streptococcal infection | Streptococci are gram-positive bacteria. Among the beta-hemolytic streptococci, Streptococcus pyogenes (Group A streptococci, GAS) and Streptococcus agalactiae (Group B streptococci, GBS) are major human ... | Bacterial infectious disease | |
| H00334 |
Bacterial endocarditis Infective endocarditis |
Infective endocarditis is a microbial infection of the endocardial surface of the heart. The characteristic lesion, a vegetation, is composed of a collection of platelets, fibrin, microorganisms, and inflammatory ... | Bacterial infectious disease | |
| H00335 | Foodborne Clostridium perfringens intoxication | Clostridium perfringens is a spore-forming, gram-positive, anaerobic bacterium consisting of five types (A-E), according to the major toxins they produce. It causes two different foodborne diseases: Type ... | Bacterial infectious disease | |
| H00336 |
Gas gangrene Clostridial myonecrosis |
Gas gangrene is a rare and devastating wound infection. The Clostridium perfringens, septicum, and histolyticum are the principal causes of trauma-associated gas gangrene. It is characterized by fever ... | Bacterial infectious disease | |
| H00337 | Tetanus | Tetanus is a serious, often fatal intoxication caused by infection of Clostridium tetani, a gram-positive bacterium, through cuts or wounds. Mortality rate among untreated patients is high. Tetanus affects ... | Bacterial infectious disease | |
| H00338 | Pseudomembranous colitis | Clostridium difficile is a gram-positive anaerobic bacillus that causes a broad spectrum of clinical symptoms ranging from mild diarrhea to severe pseudomembranous colitis. C. difficile can be transmitted ... | Bacterial infectious disease | |
| H00339 | Botulism | Botulism is an acute neuroparalytic illness caused by a botulinum toxin produced by Clostridium botulinum, an anaerobic, gram-positive bacterium. Botulism occurs in four forms: foodborne, wound, infant ... | Bacterial infectious disease | |
| H00340 | Vancomycin-resistant enterococci infection | Enterococci are gram-positive, facultative bacteria with low intrinsic virulence that constitute the normal colonizing flora of the human gastrointestinal tract. Vancomycin-resistant enterococci (VRE) ... | Bacterial infectious disease | |
| H00341 | Mycoplasma pneumonia | Mycoplasmas represent the smallest self-replicating organisms that are most closely related to the gram-positive bacterial group that includes streptococci, bacilli, and lactobacilli. Mycoplasma pneumoniae ... | Bacterial infectious disease | |
| H00342 | Tuberculosis | Tuberculosis is an infectious disease caused by strains of mycobacteria, mainly Mycobacterium tuberculosis, resulting in an estimated two million deaths each year worldwide, more than from any other single ... | Bacterial infectious disease | hsa05152 Tuberculosis |
| H00343 | Diphtheria | Diphtheria is a contagious and potentially life-threatening childhood disease caused by Corynebacterium diphtheriae. In industrialized countries, immunization against diphtheria became widespread in the ... | Bacterial infectious disease | |
| H00344 |
Leprosy Hansen disease |
Leprosy, also called Hansen's disease, is a chronic infection caused by Mycobacterium leprae (M. leprae) and the more recently discovered Mycobacterium lepromatosis (M. lepromatosis). It primarily affects ... | Bacterial infectious disease | |
| H00345 | Nocardiosis | Nocardiosis is an uncommon gram-positive bacterial infection that affects mainly patients with deficient cell-mediated immunity. It has been reported worldwide in all ages and ethnic groups. Pulmonary ... | Bacterial infectious disease | |
| H00346 |
Extrinsic allergic alveolitis Hypersensitivity pneumonitis |
Extrinsic allergic alveolitis (EAA), also known as hypersensitivity pneumonitis, is caused by repeated inhalation of mainly organic antigens by sensitized subjects. This induces a hypersensitivity response ... | Immune system disease | |
| H00347 | Chlamydia infection | Chlamydia trachomatis is a gram-negative, obligate intracellular bacterium that causes the most common sexually transmissible diseases in the world. Chlamydial infection can cause cervicitis in women and ... | Bacterial infectious disease | |
| H00348 | Lymphogranuloma venereum | Chlamydia trachomatis is a gram-negative, obligate intracellular bacterium that causes the most common sexually transmissible diseases in the world. Serovars L1, L2, L2a and L3 of C. trachomatis are the ... | Bacterial infectious disease | |
| H00349 | Trachoma | Trachoma is the leading infectious cause of blindness worldwide. Infections with serovars A, B, Ba, and C of Chlamydia trachomatis cause chronic keratoconjunctivitis in children with subsequent scarring ... | Bacterial infectious disease | |
| H00350 |
Psittacosis Parrot fever |
Psittacosis, also known as parrot disease, is an infectious disease caused by Chlamydophila psittaci, a gram-negative intracellular bacterium that is usually transmitted to humans from birds. Symptoms ... | Bacterial infectious disease | |
| H00351 | Chlamydial pneumonia | Chlamydophila (Cp.) pneumoniae is an obligate intracellular bacteria that causes human respiratory infections. Most acute respiratory infections are asymptomatic or mildly symptomatic. Repeated or prolonged ... | Bacterial infectious disease | |
| H00352 | Whipple disease | Whipple disease (WD) is a rare chronic multi-system disease associated with the bacterium Tropheryma whipplei that is ubiquitously present in the environment. The clinical features of WD are non-specific ... | Bacterial infectious disease | |
| H00353 |
Lyme borreliosis Lyme disease |
Lyme borreliosis is the multisystem infectious disease caused by the tick-borne spirochetes Borrelia. Localized infection is typically manifested by erythema migrans skin lesions. A broad variety of peripheral ... | Bacterial infectious disease | |
| H00354 | Syphilis | Syphilis is one of the oldest recognized venereal infections caused by the spirochete Treponema pallidum subsp. pallidum. It is characterized by genital ulceration, skin rash, and development of serious ... | Bacterial infectious disease | |
| H00355 |
Leptospirosis Weil disease |
Leptospirosis is a zoonosis, caused by pathogenic spirochetes belonging to the genus Leptospira. Many mammalian species and amphibians may act as reservoirs. Leptospira colonize the renal tubules of chronically ... | Bacterial infectious disease | |
| H00356 | Cryptosporidiosis | Human cryptosporidiosis is a self-limited diarrheal disease characterized by acute, persistent, or chronic diarrhea and biliary/pulmonary disease. Transmission of the causative agent, Cryptosporidium, ... | Parasitic infectious disease | |
| H00357 |
African trypanosomiasis Sleeping sickness |
African trypanosomiasis is a parasitic disease affecting both humans and livestock. It is one of the most common serious protozoan infections in sub-Saharan Africa, especially in areas of conflict. Its ... | Parasitic infectious disease | hsa05143 African trypanosomiasis |
| H00358 |
Chagas disease American trypanosomiasis |
Chagas disease, also known as American trypanosomiasis, is caused by infection with protozoan parasite Trypanosoma cruzi. The infection is transmitted by hematophagous reduviid insect vectors through fecal ... | Parasitic infectious disease | hsa05142 Chagas disease |
| H00359 | Leishmaniasis | Leishmaniasis is a vector-borne disease that affects millions of people especially in developing countries of Africa, the Americas, and Asia. Leishmaniasis is caused by a protozoan parasite of the genus ... | Parasitic infectious disease | hsa05140 Leishmaniasis |
| H00360 | Amoebiasis | Amoebiasis is a parasitic disease of gastrointestinal tract caused by Entamoeba histolytica (E. histolytica), an extracellular parasitic protozoan. People living in Central and South America and Africa ... | Parasitic infectious disease | hsa05146 Amoebiasis |
| H00361 | Malaria | Malaria, the most common parasitic disease in the world, is caused by Plasmodium parasites that are transmitted by female Anopheline mosquitoes. Plasmodium infections result in a spectrum of clinical effects ... | Parasitic infectious disease | hsa05144 Malaria |
| H00362 |
Giardiasis Lambliasis |
Giardiasis is one of the most common parasite-induced diarrhea caused by the protozoan parasite Giardia lamblia. Infection is transmitted by ingestion of contaminated water or food, or by person-to-person ... | Parasitic infectious disease |
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