KEGG ORTHOLOGY: K11101

ORTHOLOGY: K11101

Entry

K11101                      KO

Symbol

PTCH2

Name

patched 2

Pathway

map04340

Hedgehog signaling pathway

map05200

Pathways in cancer

map05217

Basal cell carcinoma

Disease

H00039

Basal cell carcinoma

H01667

Medulloblastoma

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    K11101  PTCH2; patched 2
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K11101  PTCH2; patched 2
  09162 Cancer: specific types
   05217 Basal cell carcinoma
    K11101  PTCH2; patched 2

Other DBs

GO:	0005119 0008158

TC:	2.A.6.6.14

Genes

HSA:	8643(PTCH2)

PTR:	469185(PTCH2)

PPS:	100971308(PTCH2)

GGO:	101147630(PTCH2)

PON:	100460320(PTCH2)

NLE:	100591053(PTCH2)

HMH:	116473075(PTCH2)

MCC:	100428949(PTCH2)

MCF:	102130537(PTCH2)

MTHB:

126958883

MNI:	105494922(PTCH2)

CSAB:

103224932(PTCH2)

CATY:

105594605(PTCH2)

PANU:

101022723(PTCH2)

TGE:	112633838(PTCH2)

MLEU:

105555086(PTCH2)

RRO:	104678257(PTCH2)

RBB:	108535602(PTCH2)

TFN:	117092691(PTCH2)

PTEH:

111548815(PTCH2)

CANG:

105514678(PTCH2)

CJC:	100394151(PTCH2)

SBQ:	101032669(PTCH2)

CIMI:

108312736(PTCH2)

CSYR:

103270114(PTCH2)

MMUR:

105877453(PTCH2)

LCAT:

123634219(PTCH2)

PCOQ:

105814052(PTCH2)

OGA:	100941318(PTCH2)

MMU:	19207(Ptch2)

MCAL:

110292729(Ptch2)

MPAH:

110323075(Ptch2)

MCOC:

116096489(Ptch2)

MUN:	110546514(Ptch2)

CGE:	100753887(Ptch2)

PLEU:

114709388(Ptch2)

NGI:	103746594(Ptch2)

HGL:	101703499(Ptch2)

CPOC:

100727162(Ptch2)

CCAN:

109698893(Ptch2)

DORD:

105986077(Ptch2)

DSP:	122107784(Ptch2)

PLOP:

125355063(Ptch2)

NCAR:

124978948

MMMA:

107141833(Ptch2)

OCU:

100345434

OPI:	101524451(PTCH2)

TUP:	102502271(PTCH2)

GVR:	103607832 103609677(PTCH2)

CFA:	482519(PTCH2)

CLUD:

112642594(PTCH2)

VVP:	112914802(PTCH2)

VLG:	121481639(PTCH2)

NPO:	129520875(PTCH2)

AML:	100478607(PTCH2)

UMR:	103670897(PTCH2)

UAH:	113254756(PTCH2)

UAR:	123793775(PTCH2)

ELK:

111143114

LLV:

125098898

MPUF:

101670973(PTCH2)

MNP:	132000773(PTCH2)

MLK:	131808977(PTCH2)

NVS:	122899890(PTCH2)

ORO:	101384506(PTCH2)

EJU:	114224138(PTCH2)

ZCA:	113926440(PTCH2)

MLX:	118019497(PTCH2)

NSU:	110574995(PTCH2)

LWW:	102744380(PTCH2)

FCA:	101089126(PTCH2)

PYU:	121027023(PTCH2)

PCOO:

112869290(PTCH2)

PBG:	122480414(PTCH2)

PVIV:

125173383(PTCH2)

LRUF:

124515976

PTG:	102958893(PTCH2)

PPAD:

109254823(PTCH2)

PUC:

125913517

AJU:

106970235

HHV:	120236056(PTCH2)

BTA:	507948(PTCH2)

BOM:	102273702(PTCH2)

BIU:	109556373(PTCH2)

BBUB:

102406773(PTCH2)

BBIS:

104994309(PTCH2)

CHX:	102188011(PTCH2)

OAS:	101110291(PTCH2)

BTAX:

128045380(PTCH2)

ODA:	120856207(PTCH2)

CCAD:

122437063(PTCH2)

SSC:	100623280(PTCH2)

CFR:	102506024(PTCH2)

CBAI:

105061949(PTCH2)

CDK:	105090882(PTCH2)

VPC:	102529277(PTCH2)

BACU:

103017556(PTCH2)

BMUS:

118898935(PTCH2)

LVE:	103071998(PTCH2)

OOR:	101281559(PTCH2)

DLE:	111175732(PTCH2)

PCAD:

102991392(PTCH2)

PSIU:

116744043(PTCH2)

NASI:

112411677(PTCH2)

ECB:	100052702(PTCH2)

EPZ:	103548300(PTCH2)

EAI:	106822746(PTCH2)

MYB:	102256455(PTCH2)

MYD:	102752006(PTCH2)

MMYO:

118676500(PTCH2)

MLF:	102442277(PTCH2)

PKL:	118723724(PTCH2)

EFUS:

103294797(PTCH2)

MNA:	107526709(PTCH2)

DRO:	112314543(PTCH2)

SHON:

119003353(PTCH2)

AJM:	119052368(PTCH2)

PDIC:

114497477(PTCH2)

PHAS:

123831801(PTCH2)

MMF:	118626395(PTCH2)

PPAM:

129069114(PTCH2)

HAI:	109383434(PTCH2)

RFQ:	117027700(PTCH2)

PALE:

102887248(PTCH2)

PGIG:

120619682(PTCH2)

PVP:	105297117(PTCH2)

RAY:	107499374(PTCH2)

MJV:	108389962(PTCH2)

TOD:	119235998(PTCH2)

SARA:

101559015(PTCH2)

SETR:

126011004(PTCH2)

LAV:	100671301(PTCH2)

TMU:

101354158

ETF:	101662403(PTCH2)

DNM:	101438590(PTCH2)

MDO:	100024924(PTCH2)

GAS:	123254409(PTCH2)

SHR:	100916643(PTCH2)

AFZ:

127561688

PCW:	110209268(PTCH2)

OAA:	103167620(PTCH2)

GGA:	374187(PTCH2)

PCOC:

116234005(PTCH2)

MGP:	100546150(PTCH2)

CJO:	107317516(PTCH2)

TPAI:

128072474(PTCH2)

LMUT:

125693273(PTCH2)

NMEL:

110402707(PTCH2)

APLA:

101795536(PTCH2)

ACYG:

106032960(PTCH2)

CATA:

118243436(PTCH2)

AFUL:

116491885(PTCH2)

TGU:	100230853(PTCH2)

LSR:

110469569

SCAN:

103815168(PTCH2)

PMOA:

120503343(PTCH2)

OTC:	121345118(PTCH2)

PRUF:

121362051(PTCH2)

GFR:	102044466(PTCH2)

FAB:

101819097

OMA:	130255967(PTCH2)

PHI:	102108629(PTCH2)

PMAJ:

107208460(PTCH2)

CCAE:

111932906(PTCH2)

CCW:	104695250(PTCH2)

CBRC:

103621982(PTCH2)

ETL:	114061960(PTCH2)

ZAB:	102063642(PTCH2)

ACHL:

103799845(PTCH2)

SVG:	106850685(PTCH2)

MMEA:

130589306(PTCH2)

HRT:	120756549(PTCH2)

FPG:	101914457(PTCH2)

FCH:	102050332(PTCH2)

CLV:	102089806(PTCH2)

EGZ:	104126290(PTCH2)

NNI:	104015552(PTCH2)

EHS:	104514390(PTCH2)

ACUN:

113482829(PTCH2)

TALA:

116963536(PTCH2)

PADL:

103919165(PTCH2)

AFOR:

103905703(PTCH2)

ACHC:

115349398(PTCH2)

HLE:	104841206(PTCH2)

AGEN:

126042146

GCL:

127019154

BREG:

104635005

LDI:	104344252(PTCH2)

MNB:	103781875(PTCH2)

OHA:	104339522(PTCH2)

NNT:	104410381(PTCH2)

SHAB:

115611496(PTCH2)

DPUB:

104301624(PTCH2)

ACAR:

104526870

CPEA:

104396699(PTCH2)

AVIT:

104272305(PTCH2)

CVF:	104286276(PTCH2)

RTD:	128913877(PTCH2)

CUCA:

104057577(PTCH2)

TEO:	104377951(PTCH2)

BRHI:

104502375(PTCH2)

AAM:	106500304(PTCH2)

AROW:

112975962(PTCH2)

NPD:	112943071(PTCH2)

TGT:	104575738(PTCH2)

DNE:	112985278(PTCH2)

SCAM:

104148006(PTCH2)

ASN:	102374613(PTCH2)

AMJ:	106737350(PTCH2)

CPOO:

109306992(PTCH2)

GGN:	109305317(PTCH2)

CMY:	102934849(PTCH2)

CCAY:

125641510(PTCH2)

DCC:	119860758(PTCH2)

CPIC:

101936553(PTCH2)

CABI:

116838966(PTCH2)

MRV:	120370390(PTCH2)

ACS:	100553438(ptch2)

ASAO:

132773855(PTCH2)

PVT:	110073763(PTCH2)

SUND:

121928311(PTCH2)

PBI:	103067659(PTCH2)

PMUR:

107283405(PTCH2)

CTIG:

120310806(PTCH2)

TSR:	106547853(PTCH2)

PGUT:

117664144(PTCH2)

APRI:

131194104(PTCH2)

PTEX:

113440718(PTCH2)

NSS:	113410879(PTCH2)

VKO:	123029214(PTCH2)

PMUA:

114599079(PTCH2)

PRAF:

128415856(PTCH2)

ZVI:	118088566(PTCH2)

HCG:	128322981(PTCH2)

GJA:	107107911(PTCH2)

STOW:

125432872(PTCH2)

EMC:	129330970(PTCH2)

XLA:	100191013(ptch2.L) 397836(ptch2.S)

XTR:	100492958(ptch2)

NPR:	108802368(PTCH2)

RTEM:

120921874(PTCH2)

BBUF:

120979417(PTCH2)

BGAR:

122943306(PTCH2)

MUO:	115472958(PTCH2)

GSH:	117346388(PTCH2)

DRE:	30181(ptch2)

SRX:	107720855 107722076

SANH:

107657459 107700991

SGH:	107557169 107599897

CCAR:

109058463 109058479

CAUA:

113038251 113045535

CGIB:

127951596 128030817

PTET:

122326448(ptch2)

LROH:

127153576(ptch2)

OMC:	131527141(ptch2)

PPRM:

120465132(ptch2)

RKG:	130074007(ptch2)

MAMB:

125250228(ptch2)

CIDE:

127502570

MASI:

127441589 127442770

TROS:

130554882(ptch2)

TDW:	130418308(ptch2)

MANU:

129442021(ptch2)

IPU:

108267803

PHYP:

113540269(ptch2)

SMEO:

124387724(ptch2)

TFD:	113634649(ptch2)

TVC:	132848346(ptch2)

AMEX:

103021456

CMAO:

118825869(ptch2)

EEE:	113590220(ptch2)

CHAR:

105898662(ptch2)

TRU:

101078434

TFS:	130539525(ptch2)

TNG:	GSTEN00028382G001

LCO:	104936684(ptch2)

NCC:

104943035

TBEN:

117488936(ptch2)

CGOB:

115022928(ptch2)

PGEO:

117463028(ptch2)

GACU:

117558381(ptch2)

EMAC:

134866645(ptch2)

ELY:	117272326(ptch2)

EFO:	125902483(ptch2)

PLEP:

121951770(ptch2)

SLUC:

116046123(ptch2)

ECRA:

117954508(ptch2)

ESP:	116699314(ptch2)

PFLV:

114565791(ptch2)

GAT:	120816305(ptch2)

PPUG:

119209608(ptch2)

AFB:	129114227(ptch2)

CLUM:

117746573(ptch2)

PSWI:

130198573(ptch2)

MSAM:

119902126(ptch2)

SCHU:

122886771(ptch2)

CUD:	121520775(ptch2)

ALAT:

119011808(ptch2)

MZE:	101474729(ptch2)

ONL:

100692939

OAU:	116332867(ptch2)

OLA:	101159383(ptch2)

OML:	112147636(ptch2)

CSAI:

133452700(ptch2)

XMA:	102217654(ptch2)

XCO:	114146891(ptch2)

XHE:	116722038(ptch2)

PRET:

103479622(ptch2)

PFOR:

103148304(ptch2)

PLAI:

106948976(ptch2)

PMEI:

106925691(ptch2)

GAF:	122840830(ptch2)

PPRL:

129362021(ptch2)

CVG:	107083772(ptch2)

CTUL:

119786120(ptch2)

GMU:	124870242(ptch2)

NFU:	107383993(ptch2)

KMR:	108239668(ptch2)

ALIM:

106534840(ptch2)

NWH:	119415114(ptch2)

AOCE:

111568079(ptch2)

MCEP:

125011290(ptch2)

CSEM:

103396047(ptch2)

SSEN:

122774529(ptch2)

HHIP:

117777937(ptch2)

HSP:	118118380(ptch2)

SMAU:

118311347(ptch2)

LCF:

108883493

SDU:	111228875(ptch2)

SLAL:

111654484(ptch2)

XGL:	120798452(ptch2)

HCQ:	109516881(ptch2)

SSCV:

125984748

SBIA:

133510719(ptch2)

PEE:	133411411(ptch2)

PTAO:

133488605(ptch2)

BPEC:

110159317(ptch2)

MALB:

109957709(ptch2)

BSPL:

114844582(ptch2)

SJO:	128368716(ptch2)

SASA:

106569083 106599390

STRU:

115157002 115169769

OTW:	112227380 112260463(ptch2)

OMY:	110508734 110530315(ptch2)

OGO:	124009778 124041864

ONE:	115103090 115114417

OKI:	109872322 109875463

OKE:	118394650 118402111

SALP:

111956836 111956846

SNH:	120020082 120055874

CCLU:

121535217 121580918

ELS:	105022690(ptch2)

SFM:	108934948(ptch2)

AANG:

118229113(ptch2)

LOC:	102689677(ptch2)

PSPA:

121294119(ptch2) 121327287

ARUT:

117403167(ptch2) 117416430

PSEX:

120514424(ptch2)

LCM:

102351678

CMK:	103182823(ptch2)

RTP:	109919118(ptch2)

CPLA:

122554280(ptch2)

HOC:	132819128(ptch2)

LERI:

129700864(ptch2)

PMRN:

LRJ:

BFO:

BBEL:

LPIC:

SGRE:

IEL:

PVUL:

GAE:

MCAF:

ATEN:

PPP:	112281322 112285388

EHX:	EMIHUDRAFT_312240 EMIHUDRAFT_460413

» show all

Reference

PMID:14613484

Authors

Rahnama F, Toftgard R, Zaphiropoulos PG

Title

Distinct roles of PTCH2 splice variants in Hedgehog signalling.

Journal

Biochem J 378:325-34 (2004)
DOI:10.1042/BJ20031200

Sequence

[hsa:8643]

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