KEGG ORTHOLOGY: K01394

ORTHOLOGY: K01394

Entry

K01394                      KO

Symbol

MMP3

Name

matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]

Pathway

map04657

IL-17 signaling pathway

map04668

TNF signaling pathway

map05171

Coronavirus disease - COVID-19

map05202

Transcriptional misregulation in cancer

map05215

Prostate cancer

map05323

Rheumatoid arthritis

map05417

Lipid and atherosclerosis

Disease

H01742

Coronary artery disease

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase)
09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase)
09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase)
  09162 Cancer: specific types
   05215 Prostate cancer
    K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase)
  09163 Immune disease
   05323 Rheumatoid arthritis
    K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase)
Enzymes [BR:ko01000]
3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.17  stromelysin 1
     K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase)
Peptidases and inhibitors [BR:ko01002]
Metallo peptidases
  Family M10
   K01394  MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase)

Genes

HSA:	4314(MMP3)

PTR:	451511(MMP3)

PPS:	100995831(MMP3)

GGO:	101131989(MMP3)

PON:	100461529(MMP3)

NLE:	100583082(MMP3)

HMH:	116464292 116464293

MCC:	703762(MMP3)

MCF:	102142651(MMP3)

MTHB:

126936369

MNI:	105493711(MMP3)

CSAB:

103248344(MMP3)

CATY:

105588770(MMP3)

PANU:

101000789(MMP3)

TGE:	112607314(MMP3)

MLEU:

105542745(MMP3)

RRO:	104674668(MMP3)

RBB:	108514072(MMP3)

TFN:	117081262(MMP3)

PTEH:

111540075(MMP3)

CANG:

105500946(MMP3)

CJC:

100396218

SBQ:	101051562(MMP3)

CIMI:

108315431(MMP3)

CSYR:

MMUR:

LCAT:

PCOQ:

OGA:

MMU:	17392(Mmp3)

MCAL:

110301975

MPAH:

110327820

RNO:	171045(Mmp3)

MCOC:

116072442

ANU:

117699631

MUN:

110558090

CGE:	100754565(Mmp3)

MAUA:

PROB:

PLEU:

MORG:

MFOT:

AAMP:

NGI:	103731587(Mmp3)

HGL:	101702569 101716622(Mmp3)

CPOC:

100729101(Mmp3)

CCAN:

109689285

DORD:

105980671

DSP:	122110302(Mmp3)

PLOP:

125349681

NCAR:

124958931

MMMA:

107145902

OCU:	100009111(MMP3)

OPI:

101528146

TUP:	102489067(MMP3)

GVR:	103600379(MMP3)

CFA:	403445(MMP3)

CLUD:

112671545

VVP:

112925877

VLG:	121500272(MMP3)

NPO:

129497419

AML:	100477912 100478420

UMR:	103662452 103662454

UAH:	113259796 113259798

UAR:	123792353 123792355

ELK:

111153872

LLV:	125078732 125078733

MPUF:

MNP:

MLK:

NVS:

ORO:	101368994(MMP3)

EJU:	114211354(MMP3)

ZCA:

113914358

MLX:	118013056(MMP3)

NSU:

110586166

LWW:	102733397 102734593

FCA:

PYU:

PCOO:

PBG:

PVIV:

LRUF:

PTG:

PPAD:

PUC:

AJU:

HHV:

BTA:	281309(MMP3)

BOM:	102288330(MMP3)

BIU:

109569248

BBUB:

102413066(MMP3)

BBIS:

104987808(MMP3)

CHX:	102170893(MMP3)

OAS:

101118895

BTAX:

128060536

ODA:	120876149(MMP3)

CCAD:

122450308

MBEZ:

129553537

SSC:	396769(MMP3)

CFR:	102516794(MMP3)

CBAI:

105067594(MMP3)

CDK:	105087168(MMP3)

VPC:	102528182(MMP3)

BACU:

103010042(MMP3)

BMUS:

118899355

LVE:	103089307(MMP3)

OOR:

DLE:

PCAD:

PSIU:

NASI:

ECB:	100034195(MMP3)

EPZ:	103552637(MMP3)

EAI:

106843118

MYB:	102252870 102254078

MYD:	102770528(MMP3)

MMYO:

MLF:

PKL:

EFUS:

MNA:

DRO:

SHON:

AJM:

PDIC:

PHAS:

MMF:

PPAM:

RFQ:	117031216 117031218

PALE:

PGIG:

PVP:

RAY:

MJV:	108385898(MMP3)

TOD:	119240915(MMP10)

SARA:

101545129

SETR:

126016049(MMP10)

LAV:

100660303

TMU:

101341271

ETF:	101656613 101657229

DNM:

101447627

MDO:	100011059(MMP3)

GAS:

SHR:

AFZ:

PCW:

OAA:

GGA:	418981(MMP10) 428086(MMP3)

PCOC:

116230607 116230616

MGP:	100544485 100544642

CJO:	107308380 107308400

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

CATA:

AFUL:

TGU:	100221422 100227226

LSR:	110470043 110470055

SCAN:

103812522 103827285

PMOA:

120506631 120506743

OTC:	121342518 121342531

PRUF:

121364175 121364179

GFR:	102045216 102045385

FAB:	101805628 101805825

OMA:	130252196 130258586

PHI:	102111122 102111311

PMAJ:

107199793 107213689

CCAE:

111924322 111924329

CCW:	104690061 104690062

CBRC:

103617949 103617950

ETL:

114067039

ZAB:	102069814 102069989

ACHL:

103811760 103811761

SVG:	106859369 106859372

MMEA:

130576287 130576288

HRT:	120748617 120749377

FPG:	101924760(MMP3)

FCH:

102050939

CLV:	102089434 102089618

EGZ:	104128904 104128911

NNI:

PCRI:

PLET:

EHS:

PCAO:

ACUN:

TALA:

PADL:

AFOR:

ACHC:

HALD:

HLE:	104828448 104828449

AGEN:

126048148 126048150

GCL:	127021506 127021519

CCRI:

104159689 104163036

CSTI:

104549815 104556371

CMAC:

104474429 104474600

MUI:	104535899 104537560

BREG:

104633765 104633767

FGA:	104070480 104081957

GSTE:

104255839 104261779

LDI:	104351208 104351209

MNB:

103781317

OHA:	104333034 104333059

NNT:

SHAB:

DPUB:

PGUU:

ACAR:

CPEA:

AVIT:

CVF:	104290311 104290323

RTD:	128912492 128914125

CUCA:

104055008 104064703

TEO:	104370475 104370765

BRHI:

104489342

AAM:	106495497 106495502

AROW:

112971953 112971954

NPD:	112943711 112943717

TGT:	104571781 104571785

DNE:	112988744 112988745

SCAM:

104151759 104151760

ASN:	102380481 102386892

AMJ:	102567265 102567499

CPOO:

109305541

GGN:	109302216 109303444

PSS:	102447500 102447922

CMY:	102939197 102940374 102940592

CCAY:

125633993

DCC:	119858306 119858321 119858355

CPIC:

101931498 101931780 101932067

TST:	117871171 117871173 117871798

CABI:

116814903 116837660 116837662

MRV:	120375066 120395683 120407101

ACS:	100552454 100552651 100561433

ASAO:

132770077 132772196 132772197

PVT:	110089066 110089069 110089074

SUND:

121925768 121926153 121926847

PBI:	103067400 103067634

PMUR:

CTIG:

TSR:

PGUT:

APRI:

PTEX:

NSS:

VKO:	123029183 123029242 123029250

PMUA:

114595297 114595661 114595664

PRAF:

128412588 128412589 128412592

ZVI:	118084935 118084937

HCG:	128350660 128352362 128352530

GJA:	107119161 107119164 107119165

STOW:

125430820 125431172 125431542

EMC:	129325829 129325831 129325833 129325906 129326303 129326508

XLA:	108707763 108707764 108707765 108708732 108709141 108709142 446898(mmp3.L) 495372(mmp8.S)

XTR:	100489571 100489735 100491214 100491547 100494588(mmp8)

NPR:	108786934 108786935

RTEM:

120929026 120929033 120929034 120929035

BBUF:

120996397 120996398

BGAR:

122930903 122931173

MUO:

115468491

GSH:	117362381 117362513

IPU:	108276913(mmp30)

PHYP:

AMEX:

TRU:

ALIM:

CSEM:

POV:	109628507 109634382

LCF:	108893128(mmp30)

SDU:	111222196 111233417

SLAL:

111663517

XGL:	120791805 120802392(mmp30)

HCQ:

MALB:

LOC:

ARUT:

CMK:	103177428 103177583

CPLA:

122550420 122550421 122551103 122551104

HOC:	132816339 132816340 132816341

BBEL:

MQU:

FOC:

PDAM:

Reference

PMID:3360803

Authors

Saus J, Quinones S, Otani Y, Nagase H, Harris ED Jr, Kurkinen M

Title

The complete primary structure of human matrix metalloproteinase-3. Identity with stromelysin.

Journal

J Biol Chem 263:6742-5 (1988)

Sequence

[hsa:4314]

LinkDB

DBGET integrated database retrieval system