KEGG   DRUG: エスシタロプラムシュウ酸塩
エントリ  
D02567                      Drug                                   
一般名   
エスシタロプラムシュウ酸塩 (JAN);
Escitalopram oxalate (JAN/USP)
商品名   
米国の商品 
  後発品
ESCITALOPRAM (A-S Medication Solutions), ESCITALOPRAM (A-S Medication Solutions), ESCITALOPRAM (A-S Medication Solutions), ESCITALOPRAM (A-S Medication Solutions), ESCITALOPRAM (A-S Medication Solutions), ESCITALOPRAM (Accord Healthcare), ESCITALOPRAM OXALATE (Amneal Pharmaceuticals LLC), ESCITALOPRAM (Aphena Pharma Solutions - Tennessee), ESCITALOPRAM OXALATE (Aphena Pharma Solutions - Tennessee), ESCITALOPRAM (BluePoint Laboratories), ESCITALOPRAM (Bryant Ranch Prepack), ESCITALOPRAM (Bryant Ranch Prepack), ESCITALOPRAM (Bryant Ranch Prepack), ESCITALOPRAM (Bryant Ranch Prepack), ESCITALOPRAM (Bryant Ranch Prepack), ESCITALOPRAM (Bryant Ranch Prepack), ESCITALOPRAM (Bryant Ranch Prepack), ESCITALOPRAM (Bryant Ranch Prepack), ESCITALOPRAM (Cadila Healthcare Limited), ESCITALOPRAM OXALATE (Cipla USA), ESCITALOPRAM (Denton Pharma), ESCITALOPRAM (DirectRX), ESCITALOPRAM OXALATE (Exelan Pharmaceuticals), ESCITALOPRAM (Lannett Company), ESCITALOPRAM OXALATE (Legacy Pharmaceutical Packaging), ESCITALOPRAM (Macleods Pharmaceuticals Limited), ESCITALOPRAM (NCS HealthCare of KY), ESCITALOPRAM (NCS HealthCare of KY), ESCITALOPRAM (Northwind Pharmaceuticals), ESCITALOPRAM (Northwind Pharmaceuticals), ESCITALOPRAM (NuCare Pharmaceuticals), ESCITALOPRAM (NuCare Pharmaceuticals), ESCITALOPRAM (NuCare Pharmaceuticals), ESCITALOPRAM (NuCare Pharmaceuticals), ESCITALOPRAM (NuCare Pharmaceuticals), ESCITALOPRAM (NuCare Pharmaceuticals), ESCITALOPRAM (PD-Rx Pharmaceuticals), ESCITALOPRAM (PD-Rx Pharmaceuticals), ESCITALOPRAM (Preferred Pharmaceuticals), ESCITALOPRAM (Preferred Pharmaceuticals), ESCITALOPRAM (Preferred Pharmaceuticals), ESCITALOPRAM (Preferred Pharmaceuticals), ESCITALOPRAM (Proficient Rx LP), ESCITALOPRAM (Proficient Rx LP), ESCITALOPRAM (Proficient Rx LP), ESCITALOPRAM (QPharma), ESCITALOPRAM (QPharma), ESCITALOPRAM (Quality Care Products), ESCITALOPRAM (Quality Care Products), ESCITALOPRAM OXALATE (REMEDYREPACK), ESCITALOPRAM (REMEDYREPACK), ESCITALOPRAM (REMEDYREPACK), ESCITALOPRAM (REMEDYREPACK), ESCITALOPRAM (REMEDYREPACK), ESCITALOPRAM (REMEDYREPACK), ESCITALOPRAM (REMEDYREPACK), ESCITALOPRAM (REMEDYREPACK), ESCITALOPRAM (REMEDYREPACK), ESCITALOPRAM (RPK Pharmaceuticals), ESCITALOPRAM (RPK Pharmaceuticals), ESCITALOPRAM (RedPharm Drug), ESCITALOPRAM (RedPharm Drug), ESCITALOPRAM (RedPharm Drug), ESCITALOPRAM (RedPharm Drug), ESCITALOPRAM (RedPharm Drug), ESCITALOPRAM (SOLCO HEALTHCARE US), ESCITALOPRAM (St. Mary's Medical Park Pharmacy), ESCITALOPRAM (St. Mary's Medical Park Pharmacy), ESCITALOPRAM (medsource pharmaceuticals), ESCITALOPRAM (A-S Medication Solutions), ESCITALOPRAM OXALATE (A-S Medication Solutions), ESCITALOPRAM OXALATE (ATLANTIC BIOLOGICALS CORP), ESCITALOPRAM (American Health Packaging), ESCITALOPRAM OXALATE (Amneal Pharmaceuticals LLC), ESCITALOPRAM OXALATE (Aurobindo Pharma Limited), ESCITALOPRAM (Aurobindo Pharma Limited), ESCITALOPRAM (BluePoint Laboratories), ESCITALOPRAM (Bryant Ranch Prepack), ESCITALOPRAM OXALATE (Bryant Ranch Prepack), ESCITALOPRAM OXALATE (Bryant Ranch Prepack), ESCITALOPRAM OXALATE (Bryant Ranch Prepack), ESCITALOPRAM OXALATE (Camber Pharmaceuticals), ESCITALOPRAM OXALATE (Cardinal Health), ESCITALOPRAM OXALATE (DIRECT RX), ESCITALOPRAM OXALATE (Denton Pharma), ESCITALOPRAM OXALATE (Denton Pharma), ESCITALOPRAM OXALATE (Denton Pharma), ESCITALOPRAM OXALATE (Direct Rx), ESCITALOPRAM (Jubilant Cadista Pharmaceuticals), ESCITALOPRAM OXALATE (Major Pharmaceuticals), ESCITALOPRAM OXALATE (NuCare Pharmaceuticals), ESCITALOPRAM (NuCare Pharmaceuticals), ESCITALOPRAM OXALATE (PD-Rx Pharmaceuticals), ESCITALOPRAM OXALATE (Preferred Pharmaceuticals), ESCITALOPRAM (Proficient Rx LP), ESCITALOPRAM (Proficient Rx LP), ESCITALOPRAM OXALATE (Proficient Rx LP), ESCITALOPRAM (QPharma), ESCITALOPRAM OXALATE (REMEDYREPACK), ESCITALOPRAM OXALATE (REMEDYREPACK), ESCITALOPRAM OXALATE (Rising Pharma Holdings), ESCITALOPRAM (Taro Pharmaceuticals U.S.A.), ESCITALOPRAM OXALATE (Torrent Pharmaceuticals Limited), ESCITALOPRAM OXALATE (medsource pharmaceuticals), ESCITALOPRAM (A-S Medication Solutions), ESCITALOPRAM (A-S Medication Solutions), ESCITALOPRAM (A-S Medication Solutions), ESCITALOPRAM (A-S Medication Solutions), ESCITALOPRAM (A-S Medication Solutions), ESCITALOPRAM (Lupin Pharmaceuticals), ESCITALOPRAM (NCS HealthCare of KY), ESCITALOPRAM (REMEDYREPACK)
組成式   
C20H21FN2O. C2H2O4
質量    
414.1591
分子量   
414.4268
構造式   
Simcomp   
クラス   
精神神経系用薬
 DG01659  選択的セロトニン再取り込み阻害薬 (SSRI)
代謝酵素基質薬
 DG01639  CYP2C19基質薬
 DG01644  CYP2D6基質薬
 DG01633  CYP3A/CYP3A4基質薬
  DG02913  CYP3A4基質薬
 DG02953  AOX1基質薬
 DG02917  MAO基質薬
代謝酵素阻害薬
 DG01645  CYP2D6阻害薬
コード   
薬効分類: 1179
ATCコード: N06AB10
化学構造グループ: DG00947
商品 (DG00947): D02567<JP/US>
効能    
抗うつ薬, 選択的セロトニン再取り込み阻害薬
  疾患
うつ病・うつ状態 [DS:H01646]
社会不安障害 [DS:H01670]
コメント  
シタロプラム誘導体
ターゲット 
SLC6A4 (HTT) [HSA:6532] [KO:K05037]
  パスウェイ
hsa04726  セロトニン作動性シナプス
代謝    
Enzyme: CYP3A4 [HSA:1576], CYP2C19 [HSA:1557], CYP2D6 [HSA:1565]; MAO [HSA:4128 4129], AOX1 [HSA:316]
相互作用  
CYP inhibition: CYP2D6 [HSA:1565]

構造マップ 
map07234  神経伝達物質トランスポーター阻害薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 1  神経系及び感覚器官用医薬品
  11  中枢神経系用薬
   117  精神神経用剤
    1179  その他の精神神経用剤
     D02567  エスシタロプラムシュウ酸塩 (JAN)
医療用医薬品のATC分類 [BR:jp08303]
 N 神経系
  N06 精神賦活薬
   N06A 抗うつ薬
    N06AB 選択的セロトニン再取り込み阻害薬
     N06AB10 エスシタロプラム
      D02567  エスシタロプラムシュウ酸塩 (JAN) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 抗うつ薬
  SSRIs/SNRIs(選択的セロトニン/ノルアドレナリン再取り込み阻害薬)
   エスシタロプラム
    D02567  エスシタロプラムシュウ酸塩 (JAN)
 抗不安薬
  SSRIs/SNRIs(選択的セロトニン/ノルアドレナリン再取り込み阻害薬)
   エスシタロプラム
    D02567  エスシタロプラムシュウ酸塩 (JAN)
医薬品グループ [BR:jp08330]
 精神神経系用薬
  DG01659  選択的セロトニン再取り込み阻害薬 (SSRI)
   DG00947  エスシタロプラム
    D02567  エスシタロプラムシュウ酸塩
 代謝酵素基質薬
  DG01639  CYP2C19基質薬
   DG00947  エスシタロプラム
    D02567  エスシタロプラムシュウ酸塩
  DG01644  CYP2D6基質薬
   DG00947  エスシタロプラム
    D02567  エスシタロプラムシュウ酸塩
  DG01633  CYP3A/CYP3A4基質薬
   DG02913  CYP3A4基質薬
    DG00947  エスシタロプラム
     D02567  エスシタロプラムシュウ酸塩
  DG02953  AOX1基質薬
   DG00947  エスシタロプラム
    D02567  エスシタロプラムシュウ酸塩
  DG02917  MAO基質薬
   DG00947  エスシタロプラム
    D02567  エスシタロプラムシュウ酸塩
 代謝酵素阻害薬
  DG01645  CYP2D6阻害薬
   DG00947  エスシタロプラム
    D02567  エスシタロプラムシュウ酸塩
医薬品クラス [BR:jp08332]
 精神神経系用薬
  DG01659  選択的セロトニン再取り込み阻害薬 (SSRI) [商品一覧]
   D02567  エスシタロプラムシュウ酸塩
ターゲットに基づく医薬品分類 [BR:jp08310]
 トランスポーター
  SLC ファミリー
   SLC6
    SLC6A4 (HTT)
     D02567  エスシタロプラムシュウ酸塩 (JAN) <JP/US>
日本の新薬 [jp08318.html]
 新有効成分含有医薬品
  D02567
薬物代謝酵素とトランスポーター [jp08309.html]
 薬物代謝酵素
  D02567
ゲノムバイオマーカー [jp08341.html]
 医薬品応答に影響を与える多型と変異
  D02567
医薬品グループ [BR:jp08330]
 精神神経系用薬
  DG01659  選択的セロトニン再取り込み阻害薬 (SSRI)
   DG00947  エスシタロプラム
 代謝酵素基質薬
  DG01639  CYP2C19基質薬
   DG00947  エスシタロプラム
  DG01644  CYP2D6基質薬
   DG00947  エスシタロプラム
  DG01633  CYP3A/CYP3A4基質薬
   DG02913  CYP3A4基質薬
    DG00947  エスシタロプラム
  DG02953  AOX1基質薬
   DG00947  エスシタロプラム
  DG02917  MAO基質薬
   DG00947  エスシタロプラム
 代謝酵素阻害薬
  DG01645  CYP2D6阻害薬
   DG00947  エスシタロプラム
リンク   
CAS: 219861-08-2
PubChem: 17396738
LigandBox: D02567
LinkDB    

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