KEGG ORTHOLOGY: K01763

ORTHOLOGY: K01763

Entry

K01763                      KO

Symbol

SCLY

Name

selenocysteine lyase [EC:4.4.1.16]

Pathway

map00450

Selenocompound metabolism

map01100

Metabolic pathways

Reaction

R03599

L-selenocysteine selenide-lyase (L-alanine-forming)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    K01763  SCLY; selenocysteine lyase
Enzymes [BR:ko01000]
4. Lyases
  4.4  Carbon-sulfur lyases
   4.4.1  Carbon-sulfur lyases (only sub-subclass identified to date)
    4.4.1.16  selenocysteine lyase
     K01763  SCLY; selenocysteine lyase

Other DBs

GO:

0009000

Genes

HSA:	51540(SCLY)

PTR:	460055(SCLY)

PPS:	100974077(SCLY)

GGO:	101139513(SCLY)

PON:	100432351(SCLY)

PPYG:

129032180(SCLY)

NLE:	100591935(SCLY)

HMH:	116809445(SCLY)

SSYN:

129488633(SCLY)

MCC:	695511(SCLY)

MCF:	102135683(SCLY)

MTHB:

126932610

MNI:	105473825(SCLY)

CSAB:

103218172(SCLY)

CATY:

105577973(SCLY)

PANU:

100997391(SCLY)

TGE:	112635829(SCLY)

MLEU:

105539841(SCLY)

RRO:	104658042(SCLY)

RBB:	108531916(SCLY)

TFN:	117094327(SCLY)

PTEH:

111553788(SCLY)

CANG:

105502908(SCLY)

CJC:	100414045(SCLY)

SBQ:	101033723(SCLY)

CIMI:

108310683(SCLY)

ANAN:

105731622(SCLY)

CSYR:

103260085(SCLY)

MMUR:

105866403(SCLY)

LCAT:

123643227(SCLY)

ERUF:

138381141(SCLY)

PCOQ:

105813971(SCLY)

OGA:	100950024(SCLY)

MMU:	50880(Scly)

MCAL:

110295013(Scly)

MPAH:

110321872(Scly)

RNO:	363285(Scly)

MCOC:

116088764(Scly)

ANU:	117722693(Scly)

ASYL:

127692447(Scly)

MUN:	110554315(Scly)

CGE:	100774221(Scly)

MAUA:

101826210(Scly)

PROB:

127226590(Scly)

PLEU:

114700685(Scly)

PMAV:

102903036(Scly)

MORG:

121447628(Scly)

MFOT:

126514262

AAMP:

119820991(Scly)

CNL:	130870129(Scly)

NGI:	103733606(Scly)

HGL:	101721471(Scly)

CPOC:

100714965(Scly)

CCAN:

109693291(Scly)

DORD:

105982480(Scly)

DSP:	122128031(Scly)

DMER:

138817683(Scly)

PLOP:

125350146(Scly)

NCAR:

124979964

SVUL:

306657665(SCLY)

MMMA:

107138430(Scly)

ITI:	101966423(Scly)

OCU:	100348454 100352639

OPI:	101536544(SCLY)

OCZ:	121151184(SCLY)

TUP:	102493250(SCLY)

GVR:	103601558(SCLY)

CFA:	477422(SCLY)

CLUD:

112669983(SCLY)

VVP:	112908751(SCLY)

VLG:	121497040(SCLY)

NPO:	129493717(SCLY)

AML:	100466512(SCLY)

UMR:	103662621(SCLY)

UAH:	113250124(SCLY)

UAR:	123790021(SCLY)

ELK:

111141678

LLV:

125095710

MPUF:

101686413(SCLY)

MNP:	132013691(SCLY)

MLK:	131827279(SCLY)

NVS:	122902457(SCLY)

ORO:	101369950(SCLY)

EJU:	114210787(SCLY)

ZCA:	113920106(SCLY)

MLX:	118011893(SCLY)

MANO:

123838673(SCLY)

NSU:	110570895(SCLY)

LWW:

102739062

FCA:	101088098(SCLY)

PYU:	121014364(SCLY)

PCOO:

112867589(SCLY)

PBG:	122481966(SCLY)

PVIV:

125158869(SCLY)

LRUF:

124514628

LGF:	123599699(SCLY)

AJU:

106988610

PTG:	102964442(SCLY)

PPAD:

109264835(SCLY)

PUC:

125911016

PLEZ:

122226850(SCLY)

HHV:	120229504(SCLY)

CCRU:

144226862(SCLY)

BTA:	790815(SCLY)

BOM:	102272614(SCLY)

BIU:	109556577(SCLY)

BJV:	133244947(SCLY)

BBUB:

102404476(SCLY)

BKE:	129655764(SCLY)

BBIS:

105004439(SCLY)

CHX:	102175921(SCLY)

OAS:	101110111(SCLY)

OCAN:

138437137(SCLY)

BTAX:

128044705(SCLY)

CSUM:

138072966(SCLY)

ODA:	120856503(SCLY)

CCAD:

122437305(SCLY)

MREE:

136155439(SCLY)

OVR:	110126665(SCLY)

MBEZ:

129541053(SCLY)

SSC:	100294677(SCLY)

CFR:	102520803(SCLY)

CBAI:

105063549(SCLY)

CDK:	105102866(SCLY)

VPC:	102527234(SCLY)

BACU:

103000669(SCLY)

BMUS:

118898059(SCLY)

LVE:	103091553(SCLY)

OOR:	101271963(SCLY)

LALB:

132521981(SCLY)

GMF:	115855467(SCLY)

DDP:	132428267(SCLY)

SCOO:

307187742(SCLY)

DLE:	111171979(SCLY)

PCAD:

102990298(SCLY)

PSIU:

116756949(SCLY)

PPHC:

136125744(SCLY)

NASI:

112404716(SCLY)

HAMP:

307057336(SCLY)

ECB:	100066596(SCLY)

EPZ:	103557368(SCLY)

EAI:	106832192(SCLY)

MYB:	102242534(SCLY)

MYD:	102758363(SCLY)

MMYO:

118661144(SCLY)

MLF:	102425190(SCLY)

MDT:	132238403(SCLY)

MYUM:

139015144(SCLY)

PKL:	118709109(SCLY)

EFUS:

103283230(SCLY)

POTS:

308248715(SCLY)

MNA:	107530031(SCLY)

DRO:	112308032(SCLY)

SHON:

119003044(SCLY)

AJM:	119061016(SCLY)

PDIC:

114495280(SCLY)

PHAS:

123823166(SCLY)

MMF:	118625315(SCLY)

PPAM:

129068793(SCLY)

HAI:	109374620(SCLY)

RFQ:	117026210(SCLY)

PALE:

102895737(SCLY)

PGIG:

120600972(SCLY)

PVP:	105309163(SCLY)

RAY:	107510597(SCLY)

MJV:	108386304(SCLY)

TOD:	119256340(SCLY)

SARA:

101537153(SCLY)

SFUM:

130017618(SCLY)

SETR:

126009336(SCLY)

LAV:	100677771(SCLY)

TMU:

101344905

ETF:	101638147(SCLY)

DNM:	101426846(SCLY)

MDO:	100021444(SCLY)

GAS:	123240251(SCLY)

SHR:	100923426(SCLY)

AFZ:

127558375

PCW:	110210146(SCLY)

TVP:	118846483(SCLY)

PBRV:

138157690(SCLY)

MLAO:

141490631(SCLY)

OAA:	100083120(SCLY)

TACU:

119930555(SCLY)

GGA:	424739(SCLY)

PCOC:

116231042(SCLY)

MGP:	100550094(SCLY)

CJO:	107317855(SCLY)

TPAI:

128082809(SCLY)

LMUT:

125697376(SCLY)

NMEL:

110398232(SCLY)

APLA:

101804761(SCLY)

AACU:

137861412(SCLY)

OJA:	118157646(SCLY)

ACYG:

106039261(SCLY)

CATA:

118246939(SCLY)

AFUL:

116492573(SCLY)

TGU:	100220567(SCLY)

LSR:	110474061(SCLY)

VMC:	128812074(SCLY)

VCHA:

128792851(SCLY)

AIB:	137480123(SCLY)

SCAN:

103815667(SCLY)

PMOA:

120496439(SCLY)

OTC:	121342088(SCLY)

PRUF:

121364008(SCLY)

ATRC:

139594848(SCLY)

MATE:

118689952(SCLY)

MAEN:

136560529(SCLY)

GFR:	102039775(SCLY)

FAB:	101805741(SCLY)

OMA:	130256628(SCLY)

PHI:	102105385(SCLY)

PMAJ:

107208909(SCLY)

CCAE:

111942521(SCLY)

CCW:	104696684(SCLY)

CBRC:

103612414(SCLY)

ACOE:

138114436(SCLY)

ETL:	114054825(SCLY)

ZAB:	102063429(SCLY)

ZLE:	135451932(SCLY)

ACHL:

103801243(SCLY)

SVG:	106849701(SCLY)

MMEA:

130585438(SCLY)

HRT:	120757003(SCLY)

CFAI:

136295512(SCLY)

CCIC:

134047757(SCLY)

NNT:	104405821(SCLY)

SHAB:

115611362(SCLY)

POCC:

134157545(SCLY)

FPG:	101917941(SCLY)

FCH:	102057358(SCLY)

CCRI:

104155703(SCLY)

ACUN:

113483687(SCLY)

ANOC:

141962966(SCLY)

TALA:

116961480(SCLY)

ACHC:

115346951(SCLY)

HALD:

104321982(SCLY)

HLE:	104827853(SCLY)

AGEN:

126039289

HHAR:

128148789(SCLY)

BBUT:

142032856(SCLY)

LDI:	104340235(SCLY)

DPUB:

104309987(SCLY)

PPUS:

135187024(SCLY)

IIN:	128970676(SCLY)

AVIT:

104272339(SCLY)

BRHI:

104491154(SCLY)

EGZ:	104121793(SCLY)

NNI:	104010613(SCLY)

PCRI:

104033995(SCLY)

PARX:

142059997(SCLY)

PADL:

103916930(SCLY)

AFOR:

103903692(SCLY)

FGA:	104073075(SCLY)

CBOR:

142085732(SCLY)

GSTE:

104254763(SCLY)

CBOY:

140654033(SCLY)

MAME:

142412395(SCLY)

CLV:	102084890(SCLY)

CNIC:

135991358(SCLY)

NMAY:

308043426(SCLY)

MUI:	104542666(SCLY)

PGUU:

104469855(SCLY)

PLET:

104624306(SCLY)

EHS:	104509976(SCLY)

CMAC:

104479396(SCLY)

CUCA:

104066369(SCLY)

PCUR:

138724448(SCLY)

TEO:	104382713(SCLY)

BREG:

104638523(SCLY)

ACAR:

104526183(SCLY)

CPEA:

104385125(SCLY)

CVF:	104288549(SCLY)

RTD:	128911173(SCLY)

CRID:

134517986(SCLY)

LMIC:

141744986(SCLY)

AAM:	106485697(SCLY)

AROW:

112970792(SCLY)

NPD:	112953488(SCLY)

TGT:	104573296(SCLY)

DNE:	112983446(SCLY)

SCAM:

104154197(SCLY)

ASN:	102368092(SCLY)

AMJ:	102571291(SCLY)

CIZ:	142018291(SCLY)

CMY:	102932461(SCLY)

CCAY:

125642206(SCLY)

LKP:	140917500(SCLY)

NDS:	141994147(SCLY)

DCC:	119861540(SCLY)

CPIC:

101937521(SCLY)

TST:	117882585(SCLY)

CABI:

116817083(SCLY)

MRV:	120372168(SCLY)

EMQ:	137147172(SCLY)

ACS:	100560241(scly)

ASAO:

132770787(SCLY)

PVT:	110075822(SCLY)

SUND:

121925143(SCLY)

PBI:	103057908(SCLY)

PMUR:

107285514(SCLY)

CTIG:

120309647(SCLY)

TSR:	106538390(SCLY)

PGUT:

117678520(SCLY)

PCAE:

139317803(SCLY)

APRI:

131201402(SCLY)

PTEX:

113436750(SCLY)

NSS:	113423960(SCLY)

VKO:	123025962(SCLY)

PMUA:

114597669(SCLY)

PRAF:

128414430(SCLY)

ZVI:	118093602(SCLY)

HCG:	128350328(SCLY)

GJA:	107123608(SCLY)

STOW:

125437538(SCLY)

EMC:	129331841(SCLY)

XLA:	447624(scly.L)

XTR:	496582(scly)

NPR:	108796211(SCLY)

RTEM:

120936520(SCLY)

ACAT:

141139507(SCLY)

PADS:

140328293(SCLY)

BBUF:

120997685(SCLY)

BGAR:

122933635(SCLY)

DTC:	141095293(SCLY)

PWL:	138265816(SCLY)

MUO:	115478804(SCLY)

GSH:	117366303(SCLY)

DRE:	559537(sclY)

DAES:

130230765(scly)

SRX:	107736620(scly)

SANH:

107696764(scly)

SGH:	107552249 107552250

CCAR:

109088350(scly)

CAUA:

113098922(scly)

CGIB:

127960099

PTET:

122346410(scly) 122346457

LROH:

127166412(scly)

GRF:	141346934(scly)

OMC:	131542549(scly)

PPRM:

120493122(scly)

RKG:	130081285(scly)

SCEP:

307165332(scly)

MAMB:

125273896(scly)

CIDE:

127514207

CERY:

137011123(scly)

MASI:

127445731

TROS:

130550066(scly)

TDW:	130424514(scly)

MANU:

129450372(scly)

PDAB:

135718788(scly)

IPU:

108272106

IFU:	128614874(scly)

PHYP:

113541744(scly)

SMEO:

124393583(scly)

TFD:	113642728(scly)

TVC:	132843937(scly)

CGAR:

128526827(scly)

NGRA:

132885285(scly)

TRN:	134316174(scly)

AMEX:

103029734(scly)

CMAO:

118808046(scly)

EEE:	113575890(scly)

CHAR:

105898281(scly)

SPIL:

134102214(scly)

ASAD:

121677751(scly)

TRU:	101076922(scly)

TFS:	130528431(scly)

TNG:	GSTEN00013738G001

NCC:	104962252(scly)

TBEN:

117491078(scly)

CGOB:

115007400(scly)

PGEO:

117444991(scly)

GACU:

117559029(scly)

EMAC:

134869862(scly)

ELY:	117254510(scly)

EFO:	125895304(scly)

PLEP:

121941114(scly) 121965170

SLUC:

116058694(scly)

ECRA:

117949875(scly)

ESP:	116696181(scly)

PFLV:

114561844(scly)

GAT:	120824372(scly)

PPUG:

119217142(scly)

AFB:	129094425(scly)

CLUM:

117729267(scly)

PSWI:

130193616(scly)

CANA:

137794605(scly)

CVE:	137870509(scly)

MSAM:

119901178(scly)

SCHU:

122877543(scly)

EARM:

139287954(scly)

CUD:	121512410(scly)

SPUL:

138607642(scly)

LMIX:

132957329(scly)

HTC:	141789452(scly)

ALAT:

119028895(scly)

ASTR:

137599280(scly)

PKLU:

139202880(scly)

LCO:	104926027(scly)

MZE:	101480692(scly)

ONL:	100696525(scly)

OAU:	116312969(scly)

OLA:	101165796(scly)

OML:	112136939(scly)

CSAI:

133457694(scly)

XMA:	102229960(scly)

XCO:	114150655(scly)

XHE:	116726090(scly)

PRET:

103463955(scly)

PFOR:

103130138(scly)

PLAI:

106959718(scly)

PMEI:

106925054(scly)

GAF:	122838190(scly)

PPRL:

129379913(scly)

CVG:	107097731(scly)

CTUL:

119781811(scly)

GMU:	124873428(scly)

NFU:	107387403(scly)

KMR:	108241205(scly)

ALIM:

106519384(scly)

NWH:	119408172(scly)

LTU:	140312326(scly)

MCEP:

125009136(sclY)

AOCE:

111565036(scly)

EJA:	138199019(scly)

BFRE:

138624105(scly)

LCF:

108878826

POV:	109625503(scly)

SSEN:

122780917(scly)

SSOE:

131466058(scly)

HHIP:

117760198(scly)

HSP:	118120757(scly)

PPLT:

128448503(scly)

SMAU:

118318751(scly)

SDU:	111232014(scly)

SLAL:

111669591(scly)

XGL:	120790827(scly)

HCQ:	109532344(scly)

SSCV:

125970712(scly)

SBIA:

133503397(scly)

PEE:	133405960(scly)

PTAO:

133481151(scly)

BPEC:

110154830(scly)

ENY:	140354240(scly)

MALB:

109965689(scly)

BSPL:

114854585(scly)

SJO:	128361957(scly)

SSCO:

133985037(scly)

TTY:	137188258(scly)

GMH:	115556099(scly)

SASA:

100380521(scly)

STRU:

115158880(scly)

OTW:	112247641(scly)

OMY:	110524876(scly)

OGO:	123997538(scly)

ONE:

115121853

OKI:	109879895(scly)

OKE:	118394361(scly)

OMM:	135513298(scly)

OCLA:

139409575

SALP:

112072553(scly)

SNH:	120055108(scly)

SFON:

129869472(scly)

CCLU:

121551172(scly)

ELS:	105025624(scly)

OEP:	134010970(scly)

SFM:	108925971(scly)

PKI:

111845818

AANG:

118224615(scly)

AROT:

135252534(scly)

CCOG:

133126983(scly)

LOC:	102683137(scly)

PSPA:

121323570(scly)

ARUT:

117422968(scly)

PSEX:

120535267(scly)

LCM:	102361716(SCLY)

CMK:	103188210(scly)

RTP:	109917907(scly)

CPLA:

122555742(scly)

CPUN:

140479113(scly)

HOC:	132821622(scly)

SCAU:

119976024(scly)

LERI:

129703512(scly)

HAKA:

140725348(scly)

PMRN:

116942799(SCLY)

LRJ:	133342828 133342830

BFO:

BBEL:

CIN:

SCLV:

CLEP:

SPU:

LPIC:

LVG:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

BCOO:

CLEC:

NLU:

LDA:

HVI:

MQU:	129002325 129002636

PHU:	Phum_PHUM596410

ZNE:

CSEC:

PAME:

SGRE:

BROR:

IEL:	124159231(LOC124159231)

HAMR:

139692157

FCD:

110863235

DPX:	DAPPUDRAFT_229859 DAPPUDRAFT_326277

DMK:

DPZ:

AFRA:

EAF:

LSM:

TCF:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

SPRM:

ESN:

MNZ:

MRJ:

PORN:

PPOI:

DSV:

DALB:

RSAN:

RMP:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

LPOL:

PMEO:

CEL:	CELE_F13H8.9(scly-1)

CBR:

CBG_02613

CRQ:	GCK72_006215

NAI:	NECAME_13443

BMY:	BM_BM3359(Bm3359)

LOA:	LOAG_08134

HRO:	HELRODRAFT_98239

PVUL:

PCAN:

LSAX:

BARL:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

YBA:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

LJP:

LAK:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:	100208711(LOC100208711)

HSY:

130614817

RES:

135690868

TAD:	TRIADDRAFT_57638

AQU:

100641171

CCLM:

134182736

MBR:	MONBRDRAFT_25105

SRE:	PTSG_01112

» show all

Reference

PMID:10692412

Authors

Mihara H, Kurihara T, Watanabe T, Yoshimura T, Esaki N

Title

cDNA cloning, purification, and characterization of mouse liver selenocysteine lyase. Candidate for selenium delivery protein in selenoprotein synthesis.

Journal

J Biol Chem 275:6195-200 (2000)
DOI:10.1074/jbc.275.9.6195

Sequence

[mmu:50880]

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