KEGG ORTHOLOGY: K05202

ORTHOLOGY: K05202

Entry

K05202                      KO

Symbol

GRIK2

Name

glutamate receptor, ionotropic kainate 2

Pathway

map04080

Neuroactive ligand-receptor interaction

map04082

Neuroactive ligand signaling

map04724

Glutamatergic synapse

Disease

H00768

Autosomal recessive intellectual developmental disorder

H02894

Neurodevelopmental disorder with impaired language and ataxia and with or without seizures

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05202  GRIK2; glutamate receptor, ionotropic kainate 2
   04082 Neuroactive ligand signaling
    K05202  GRIK2; glutamate receptor, ionotropic kainate 2
09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    K05202  GRIK2; glutamate receptor, ionotropic kainate 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05202  GRIK2; glutamate receptor, ionotropic kainate 2
Ion channels [BR:ko04040]
Ligand-gated channels
  Glutamate (ionotropic)
   K05202  GRIK2; glutamate receptor, ionotropic kainate 2

Other DBs

GO:	0005234 0015277

TC:	1.A.10.1.11

Genes

HSA:	2898(GRIK2)

PTR:	462899(GRIK2)

PPS:	100983583(GRIK2)

GGO:	101136381(GRIK2)

PON:	100436517(GRIK2)

PPYG:

129037930(GRIK2)

NLE:	100580676(GRIK2)

HMH:	116470209(GRIK2)

SSYN:

129471363(GRIK2)

MCC:	695660(GRIK2)

MCF:	102137990(GRIK2)

MTHB:

126952267

MNI:	105478796(GRIK2)

CSAB:

103240672(GRIK2)

CATY:

105588928(GRIK2)

PANU:

101005130(GRIK2)

TGE:	112622454(GRIK2)

MLEU:

105555602(GRIK2)

RRO:	104682683(GRIK2)

RBB:

108512380

TFN:	117097135(GRIK2)

PTEH:

111538453(GRIK2)

CANG:

105507825(GRIK2)

CJC:	100399182(GRIK2)

SBQ:	101033856(GRIK2)

CIMI:

108282592(GRIK2)

ANAN:

105707452(GRIK2)

CSYR:

103260591(GRIK2)

MMUR:

105856867(GRIK2)

LCAT:

123633107(GRIK2)

ERUF:

138395054(GRIK2)

PCOQ:

105815781

OGA:	100941325(GRIK2)

MMU:	14806(Grik2)

MCAL:

110302876(Grik2)

MPAH:

110326190(Grik2)

RNO:	54257(Grik2)

MCOC:

116074288(Grik2)

ANU:	117724750(Grik2)

ASYL:

127669478(Grik2)

MUN:	110565115(Grik2)

CGE:	100754248(Grik2)

MAUA:

101839556(Grik2)

PROB:

127237767(Grik2)

PMAV:

102924557(Grik2)

MORG:

121449276(Grik2)

MFOT:

126487413

AAMP:

119820545(Grik2)

CNL:	130863327(Grik2)

NGI:	103725641(Grik2)

HGL:	101697577(Grik2)

CPOC:

100733104(Grik2)

CCAN:

109679038

DORD:

105990074(Grik2)

DSP:	122107742(Grik2)

DMER:

138819489(Grik2)

PLOP:

125357099(Grik2)

NCAR:

124988242

MMMA:

107154074(Grik2)

ITI:	101960998(Grik2)

OCU:

100356816

OPI:	101526386(GRIK2)

OCZ:	121158782(GRIK2)

TUP:	102474140(GRIK2)

GVR:

103604624

CFA:	481938(GRIK2)

CLUD:

112658523(GRIK2)

VVP:	112923186(GRIK2)

VLG:	121497490(GRIK2)

NPO:	129512310(GRIK2)

AML:	100466021(GRIK2)

UMR:	103675867(GRIK2)

UAH:	113264696(GRIK2)

UAR:	123798529(GRIK2)

ELK:

111158270

LLV:

125103034

MPUF:

101670682(GRIK2)

MNP:	132018320(GRIK2)

MLK:	131833569(GRIK2)

NVS:	122904306(GRIK2)

ORO:	101375592(GRIK2)

EJU:	114210026(GRIK2)

ZCA:	113927129(GRIK2)

MLX:	118001497(GRIK2)

MANO:

123836286(GRIK2)

NSU:	110583612(GRIK2)

LWW:	102741029(GRIK2)

FCA:	101089440(GRIK2)

PYU:	121029827(GRIK2)

PCOO:

112862066(GRIK2)

PBG:	122489801(GRIK2)

PVIV:

125165757(GRIK2)

LRUF:

124528632

LGF:	123608776(GRIK2)

AJU:

106975265

PTG:	102962510(GRIK2)

PPAD:

109263466(GRIK2)

PLEZ:

122220217(GRIK2)

HHV:	120240073(GRIK2)

CCRU:

144228786(GRIK2)

BTA:	615226(GRIK2)

BOM:	102285083(GRIK2)

BIU:	109563879(GRIK2)

BJV:	133253914(GRIK2)

BBUB:

102404121(GRIK2)

BKE:	129619894(GRIK2)

BBIS:

104989557(GRIK2)

CHX:	102184433(GRIK2)

OAS:	101122701(GRIK2)

OCAN:

138445315(GRIK2)

BTAX:

128053101(GRIK2)

CSUM:

138089968(GRIK2)

ODA:	120862949(GRIK2)

CCAD:

122422647(GRIK2)

MREE:

136150650(GRIK2)

OVR:	110143789(GRIK2)

MBEZ:

129561155(GRIK2)

SSC:	100516526(GRIK2)

CFR:	102509183(GRIK2)

CBAI:

105077387(GRIK2)

CDK:	105097144(GRIK2)

VPC:	102527363(GRIK2)

BACU:

103002425(GRIK2)

BMUS:

118905139(GRIK2)

LVE:	103075773(GRIK2)

OOR:	101275228(GRIK2)

LALB:

132530217(GRIK2)

GMF:	115866995(GRIK2)

DDP:	132437334(GRIK2)

DLE:	111164031(GRIK2)

PCAD:

102975328(GRIK2)

PSIU:

116763443(GRIK2)

PPHC:

136132008(GRIK2)

NASI:

112395825(GRIK2)

ECB:	100066235(GRIK2)

EPZ:	103552725(GRIK2)

EAI:	106831097(GRIK2)

MYB:	102263184(GRIK2)

MYD:	102768602(GRIK2)

MMYO:

118660520(GRIK2)

MLF:	102442391(GRIK2)

MDT:	132237046(GRIK2)

MYUM:

139012304(GRIK2)

PKL:	118705395(GRIK2)

EFUS:

103296906(GRIK2)

MNA:	107542766(GRIK2)

DRO:	112296979(GRIK2)

SHON:

118996350(GRIK2)

AJM:	119042005(GRIK2)

PDIC:

114494747(GRIK2)

PHAS:

123822161(GRIK2)

MMF:	118621033(GRIK2)

PPAM:

129067663(GRIK2)

HAI:	109383322(GRIK2)

RFQ:	117018662(GRIK2)

PALE:

102896341

PGIG:

120609327(GRIK2)

PVP:	105292490(GRIK2)

RAY:	107499921(GRIK2)

MJV:	108394903(GRIK2)

TOD:	119251493(GRIK2)

SARA:

101551472(GRIK2)

SFUM:

130033343(GRIK2)

SETR:

126005994(GRIK2)

LAV:	100662247(GRIK2)

TMU:

101348335

ETF:	101637983(GRIK2)

DNM:	101441767(GRIK2)

MDO:	100020889(GRIK2)

GAS:	123247643(GRIK2)

SHR:	100932371(GRIK2)

AFZ:

127562036

PCW:	110216458(GRIK2)

TVP:	118857707(GRIK2)

PBRV:

138153030(GRIK2)

MLAO:

141487736(GRIK2)

OAA:	100074816(GRIK2)

TACU:

119940687(GRIK2)

GGA:	428628(GRIK2)

PCOC:

116240647(GRIK2)

CJO:	107311868(GRIK2)

TPAI:

128081782(GRIK2)

LMUT:

125688768(GRIK2)

NMEL:

110395430(GRIK2)

APLA:

101802922(GRIK2)

AACU:

137854451(GRIK2)

OJA:	118163828(GRIK2)

ACYG:

106032625(GRIK2)

CATA:

118255532(GRIK2)

AFUL:

116487374(GRIK2)

TGU:	100231135(GRIK2)

LSR:	110472289(GRIK2)

VMC:	128804887(GRIK2)

VCHA:

128785419(GRIK2)

AIB:	137470603(GRIK2)

SCAN:

103818901(GRIK2)

PMOA:

120511322(GRIK2)

OTC:	121341427(GRIK2)

PRUF:

121359241(GRIK2)

ATRC:

139599298(GRIK2)

MATE:

118684641(GRIK2)

MAEN:

136555037(GRIK2)

GFR:	102041866(GRIK2)

FAB:	101811250(GRIK2)

OMA:	130251620(GRIK2)

PHI:	102111190(GRIK2)

PMAJ:

107202007(GRIK2)

CCAE:

111927310

CCW:	104691837(GRIK2)

CBRC:

103619238(GRIK2)

ACOE:

138107330(GRIK2)

ETL:	114056336(GRIK2)

ZAB:	102072119(GRIK2)

ZLE:	135445186(GRIK2)

ACHL:

103807919

SVG:	106855591(GRIK2)

MMEA:

130572400(GRIK2)

HRT:	120750421(GRIK2)

SATI:

136358972(GRIK2)

CFAI:

136287097(GRIK2)

CCIC:

134042480(GRIK2)

FPG:	101914305(GRIK2)

FCH:	102054586(GRIK2)

FRS:	119150419(GRIK2)

NNT:

104408614

SHAB:

115609588(GRIK2)

POCC:

134158491(GRIK2)

ACUN:

113477739(GRIK2)

ANOC:

141968457(GRIK2)

SURA:

141940743(GRIK2)

TALA:

104360823(GRIK2)

ACHC:

115353340(GRIK2)

HLE:	104835405(GRIK2)

AGEN:

126046213

HHAR:

128139276(GRIK2)

BBUT:

142039769(GRIK2)

GCL:

127015344

DPUB:

104298072(GRIK2)

PPUS:

135189547(GRIK2)

IIN:	128975967(GRIK2)

AVIT:

104273092

EGZ:	104135415(GRIK2)

NNI:

104021926

PARX:

142054593(GRIK2)

PADL:

103913637(GRIK2)

AFOR:

103903744(GRIK2)

CBOR:

142080332(GRIK2)

CBOY:

140649999(GRIK2)

MAME:

142408219(GRIK2)

CLV:

102090990

CNIC:

135987747(GRIK2)

CUCA:

104062434(GRIK2)

PCUR:

138717596(GRIK2) 138717798

GAME:

129205100(GRIK2)

OHA:	104336032(GRIK2)

CPEA:

104394576(GRIK2)

CVF:	104294270(GRIK2)

RTD:	128906958(GRIK2)

CRID:

134513349(GRIK2)

LMIC:

141741120(GRIK2)

NARQ:

141466396(GRIK2)

AAM:	106489627(GRIK2)

AROW:

112972865(GRIK2)

NPD:

112954242

DNE:

112991246

SCAM:

104149309(GRIK2)

ASN:

102371662

AMJ:	102562673(GRIK2)

CPOO:

109311897(GRIK2)

GGN:	109299647(GRIK2)

PSS:	102450242(GRIK2)

CIZ:	142010483(GRIK2)

CMY:	102939784(GRIK2)

CCAY:

125634336(GRIK2)

LKP:	140908888(GRIK2)

NDS:	141984785(GRIK2)

DCC:	119853121(GRIK2)

CPIC:

101934860(GRIK2)

TST:	117875073(GRIK2)

EOB:	135876736(GRIK2)

CABI:

116836391(GRIK2)

MRV:	120400935(GRIK2)

EMQ:	137152049(GRIK2)

ACS:	100568226(grik2)

ASAO:

132760826(GRIK2)

PVT:	110072348(GRIK2)

SUND:

121925258(GRIK2)

PBI:

103053922

PMUR:

107293132

CTIG:

120311850(GRIK2)

TSR:

106542040

PGUT:

117660803(GRIK2)

PCAE:

139324099(GRIK2)

APRI:

131194106(GRIK2)

PTEX:

113455360(GRIK2)

NSS:	113411511(GRIK2)

VKO:	123021998(GRIK2)

PMUA:

114593296

PRAF:

128410378(GRIK2)

ZVI:	118082226(GRIK2)

HCG:	128345868(GRIK2)

GJA:	107116656(GRIK2)

STOW:

125431161(GRIK2)

EMC:	129326263(GRIK2)

XLA:	100294518(grik2.L) 378603(grik2.S)

XTR:	100495093(grik2)

NPR:

108792938

RTEM:

120937157(GRIK2)

ACAT:

141140142(GRIK2)

PADS:

140328826(GRIK2)

BBUF:

120998224(GRIK2)

BGAR:

122936217(GRIK2)

DTC:	141100820(GRIK2)

HSQ:	130362152(GRIK2)

PCOB:

134909782(GRIK2)

PWL:	138296392(GRIK2)

MUO:	115464830(GRIK2)

GSH:	117356720(GRIK2)

DRE:	101885658 556013(grik2)

DAES:

130242993(grik2)

SRX:	107714403 107740554 107758138

SANH:

107661009 107667969

SGH:	107569202 107569343 107574533

CCAR:

109044976 109059203 109068158 109105197

CAUA:

113048467 113064726 113097456 113108984

CGIB:

127974662 127979717 128028808 128030092

PTET:

122333200 122360342 122360367

LROH:

127164066 127177876(grik2)

GRF:	141333405 141343281

OMC:	131521745(grik2) 131539683

PPRM:

120462640(grik2) 120471029

RKG:	130077472 130085711(grik2)

MAMB:

125243282(grik2) 125244882

CIDE:

127497493 127510943

CERY:

137023732 137024217(grik2)

MASI:

127435174 127436426 127452521 127453870

TROS:

130547850 130558241(grik2)

TDW:

130420601

MANU:

129432334 129447669(grik2)

PDAB:

135728214(grik2) 135758736

IPU:	108271497(grik2) 108279510

IFU:	128611861(grik2) 128623714

PHYP:

113532217 113534120

SMEO:

124384376(grik2) 124401024

TFD:	113644677(grik2) 113645474

TVC:	132845777(grik2) 132859177

CGAR:

128520141(grik2) 128534250

NGRA:

132869568 132886925(grik2)

TRN:	134309935(grik2) 134313330

AMEX:

103044887 103047375(grik2)

CMAO:

118811195 118818849

EEE:	113580724 113587785

CHAR:

105901480 105910019(grik2)

SPIL:

134083093(grik2) 134097375

ASAD:

121711841 121720803(grik2)

TRU:	101071348 101075174 115250310

TFS:	130515749 130533218(grik2)

TNG:	GSTEN00023134G001

LCO:	104918405 104927045

NCC:	104943061(grik2)

TBEN:

117470796(grik2) 117493482

CGOB:

115021166(grik2) 115028855

PGEO:

117439783 117460453(grik2)

GACU:

117532914(grik2) 117556129

EMAC:

134862199(grik2) 134877213

ELY:	117265788(grik2) 117270700

EFO:	125892838(grik2) 125897199

PLEP:

121945322(grik2) 121955375

SLUC:

116035250(grik2) 116066127

SVIT:

144519047(grik2) 144533843

ECRA:

117945763(grik2) 117961488

ESP:	116690580 116705926

PFLV:

114557378(grik2) 114573110

PFLT:

120546833 120562080(grik2)

GAT:	120807737 120810159(grik2)

PPUG:

119194589 119197390(grik2)

AFB:	129107634 129110214(grik2)

CLUM:

117727440 117728054(grik2)

PSWI:

130202784 130206473(grik2)

CANA:

137781340(grik2) 137785354

CVE:	137872318 137891077(grik2)

AMIR:

142941721 142964845(grik2)

MSAM:

119898149(grik2) 119909171

SCHU:

122863420 122881547(grik2)

EARM:

139290225(grik2) 139302141

CUD:	121513575(grik2) 121521526

SPUL:

138583559(grik2) 138585378

LMIX:

132983278(grik2) 132984896

HTC:	141800369(grik2) 141802370

ALAT:

119006601(grik2) 119012681

ASTR:

137607173(grik2) 137613564

PKLU:

139204760 139217459

MZE:	101466412(grik2) 101474374

ONL:	100691032(grik2) 100702227

OAU:	116320682(grik2) 116324147

OLA:	101172189(grik2) 101173029

OML:	112143556(grik2) 112157865

CSAI:

133418624 133424872(grik2)

XMA:	102219688(grik2) 102223640

XCO:	114152757(grik2) 114158684

XHE:	116717045(grik2) 116734130

PRET:

103457461 103478802(grik2)

PFOR:

103134328(grik2)

PLAI:

106957039(grik2)

PMEI:

106920676(grik2)

GAF:	122825793 122830687(grik2)

PPRL:

129353767(grik2) 129375259

CVG:	107081635 107103501

CTUL:

119779140 119796101

GMU:	124865521(grik2) 124881923

NFU:	107377647 107378982

KMR:	108233439 108249907(grik2)

ALIM:

106526996(grik2) 106535628 106535847

NWH:

119417916

LTU:	140267252 140316892(grik2)

AOCE:

111566453 111586925(grik2)

EJA:	138203343 138211841(grik2)

BFRE:

138634109 138635072

MCEP:

124998971 125015945(grik2)

CSEM:

103380931 103388891

POV:	109632229(grik2) 109635991

SSEN:

122774443(grik2) 122783694

SSOE:

131443537 131472001(grik2)

HHIP:

117757982 117777512(grik2)

HSP:	118099814 118114063(grik2)

PPLT:

128449961(grik2) 128460090

SMAU:

118290421 118315886(grik2)

LCF:	108876295 108895996

SDU:	111225999 111236027

SLAL:

111661481 111661749

XGL:	120784310(grik2) 120788908

HCQ:	109516813 109521929

SSCV:

125974941(grik2) 125990298

SBIA:

133496791(grik2)

PEE:	133401088(grik2) 133416798

PTAO:

133468502 133479713

BPEC:

110153437

ENY:	140371509 140373512(grik2)

MALB:

109952783

BSPL:

114842678(grik2) 114849248

SJO:	128365985(grik2) 128377465

SSCO:

133984088(grik2) 133997954

TTY:	137169167 137191983(grik2)

GMH:	115534701 115554296

SASA:

106571163 106605492 106607558

STRU:

115165690 115175059 115176636 115195609

OTW:	112217391 112222782 112245008 112249829

OMY:	110512031 110521035 110529367 110538828

OGO:	123990547 123994947 123997959 124005477

ONE:	115116850 115117923 115139560 115140899

OKI:	109876212 109900537 109901194 109901670

OKE:	118367642 118367756 118374950 118386584

OMM:	135505654 135520429 135522058

OCLA:

139390762 139423656

SALP:

111954059 111964614 111964915 112069637

SNH:	120019241 120024238 120031313 120047686

SFON:

129817711 129837977 129857328

CCLU:

121543035 121549120 121552680 121586005

ELS:	105021682 105026031(grik2)

OEP:	134016622 134025291

SFM:	108929354 108937209(grik2)

PKI:	111840895(grik2)

AANG:

118226585(grik2)

AROT:

135259088(grik2)

CCOG:

133123782(grik2)

LOC:	102687609(grik2)

PSPA:

121316280 121317404

ARUT:

117402639 117410621

PSEX:

120525505(grik2)

LCM:	102359141(GRIK2)

CMK:

RTP:

CPLA:

CPUN:

HOC:

SCAU:

STOZ:

LERI:

HAKA:

PMRN:

116952928(GRIK2) 116953441 116955637

LRJ:

133357027

BFO:	118404772 118422802 118423400 118423604 118423630 118431047 118432472 118432500 118432502

BBEL:

109468466 109469330 109469335 109470568 109481052 109481086 109486020 109486375

CIN:

100175916

CLEP:

143450819

SPU:	579779 584569

LPIC:

129259435 129259436 129259437 129282830

LVG:	121406839 121412957 121412961 121413896 121413970

AJJ:	139962880 139962881

APLC:

ARUN:

AAMU:

AFIL:

AJC:	117113924 117113935

SKO:	100372244 100378462

PFLL:

139121590 139133934 139137064 139141721

GOE:

108863639

CVS:

136977170

PVUL:

126823922 126830348

LSAX:

138969362 138969363 138970899

BARL:

143283750

HASI:

137261291 137274571

HCRA:

139449085

CANU:

128156593 128186383 128186385

CVN:	111103884 111105255 111105303

OED:	125670573 125675631 125681110 125683441 125683442

AIRR:

138328044

YBA:

132545640

RPHI:

132726844

LLON:

135485502 135497297 135499019 135501396

MCAZ:

138021198

MFOO:

138009354

» show all

Reference

PMID:1648177

Authors

Egebjerg J, Bettler B, Hermans-Borgmeyer I, Heinemann S

Title

Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA.

Journal

Nature 351:745-8 (1991)
DOI:10.1038/351745a0

Sequence

[rno:54257]

LinkDB

DBGET integrated database retrieval system