ORTHOLOGY: K05228
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Entry
K05228 KO
Symbol
POMC
Name
proopiomelanocortin
Pathway
map04024
cAMP signaling pathway
map04080
Neuroactive ligand-receptor interaction
map04915
Estrogen signaling pathway
map04916
Melanogenesis
map04920
Adipocytokine signaling pathway
map04925
Aldosterone synthesis and secretion
map04927
Cortisol synthesis and secretion
map04934
Cushing syndrome
Disease
H02106
Genetic obesity
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
K05228 POMC; proopiomelanocortin
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
K05228 POMC; proopiomelanocortin
09150 Organismal Systems
09152 Endocrine system
04920 Adipocytokine signaling pathway
K05228 POMC; proopiomelanocortin
04915 Estrogen signaling pathway
K05228 POMC; proopiomelanocortin
04916 Melanogenesis
K05228 POMC; proopiomelanocortin
04925 Aldosterone synthesis and secretion
K05228 POMC; proopiomelanocortin
04927 Cortisol synthesis and secretion
K05228 POMC; proopiomelanocortin
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
K05228 POMC; proopiomelanocortin
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides
K05228 POMC; proopiomelanocortin
Cytokines and neuropeptides [BR:
ko04052
]
Neuropeptides
Neuropeptides (GPCR binding)
K05228 POMC; proopiomelanocortin
BRITE hierarchy
Genes
HSA:
5443
(POMC)
PTR:
459074
(POMC)
PPS:
100971970
(POMC)
GGO:
101147771
(POMC)
PON:
100460464
(POMC)
PPYG:
129030398
(POMC)
NLE:
100594270
(POMC)
HMH:
116480413
(POMC)
SSYN:
129468534
(POMC)
MCC:
694430
(POMC)
MCF:
102127286
(POMC)
MTHB:
126933667
MNI:
105479804
(POMC)
CSAB:
103220653
(POMC)
CATY:
105578520
(POMC)
PANU:
101008794
(POMC)
TGE:
112605009
(POMC)
MLEU:
105534022
(POMC)
RRO:
104677878
(POMC)
RBB:
108532667
(POMC)
TFN:
117062625
(POMC)
PTEH:
111554491
(POMC)
CANG:
105517819
(POMC)
CJC:
100414089
(POMC)
SBQ:
101041563
(POMC)
CIMI:
108303268
(POMC)
ANAN:
105717891
(POMC)
CSYR:
103262651
(POMC)
MMUR:
105884309
(POMC)
LCAT:
123636675
(POMC)
PCOQ:
105816888
(POMC)
OGA:
100944075
(POMC)
MMU:
18976
(Pomc)
MCAL:
110307137
(Pomc)
MPAH:
110324728
(Pomc)
RNO:
24664
(Pomc)
MCOC:
116079800
(Pomc)
ANU:
117717051
(Pomc)
MUN:
110555189
(Pomc)
CGE:
100756311
(Pomc)
MAUA:
101822777
(Pomc)
PROB:
127220053
(Pomc)
PLEU:
114697442
(Pomc)
MORG:
121439728
121439734
MFOT:
126490723
AAMP:
119808080
(Pomc)
NGI:
103746418
(Pomc)
HGL:
101718053
(Pomc)
CPOC:
100720803
(Pomc)
CCAN:
109685682
(Pomc)
DORD:
105983652
(Pomc)
DSP:
122122541
(Pomc)
PLOP:
125356932
(Pomc)
NCAR:
124963358
MMMA:
107137144
(Pomc)
OCU:
100344462
OPI:
101521946
(POMC)
TUP:
102498583
(POMC)
CFA:
403659
(POMC)
CLUD:
112664691
(POMC)
VVP:
112908494
(POMC)
VLG:
121491658
(POMC)
NPO:
129511116
(POMC)
AML:
100481656
(POMC)
UMR:
121101079
(POMC)
UAH:
113268582
(POMC)
UAR:
123799779
(POMC)
ELK:
111154189
LLV:
125109273
MPUF:
101673639
(POMC)
MNP:
132022244
(POMC)
MLK:
131808211
(POMC)
NVS:
122915799
(POMC)
ORO:
101367412
(POMC)
EJU:
114205770
(POMC)
ZCA:
113938376
(POMC)
MLX:
118007404
(POMC)
NSU:
110587409
(POMC)
LWW:
102748346
(POMC)
FCA:
101087223
(POMC)
PYU:
121044205
(POMC)
PBG:
122467116
(POMC)
PVIV:
125162078
(POMC)
LRUF:
124504250
PPAD:
109262875
(POMC)
PUC:
125937373
AJU:
106967900
HHV:
120235838
(POMC)
BTA:
281416
(POMC)
BOM:
102283767
(POMC)
BIU:
109566326
(POMC)
BBUB:
102410708
(POMC)
BBIS:
104989040
(POMC)
CHX:
102182514
(POMC)
OAS:
443212
(POMC)
BTAX:
128056566
(POMC)
ODA:
120851603
(POMC)
CCAD:
122422170
122441991
(POMC)
MBEZ:
129539306
(POMC)
SSC:
396863
(POMC)
CFR:
102516898
(POMC)
CDK:
105100044
(POMC)
BMUS:
118906098
(POMC)
LVE:
103077184
(POMC)
OOR:
101284816
(POMC)
DLE:
111174766
(POMC)
PCAD:
102991057
(POMC)
PSIU:
116764385
(POMC)
NASI:
112412792
(POMC)
ECB:
100071524
(POMC)
EPZ:
103547816
(POMC)
EAI:
106841107
(POMC)
MMYO:
118669498
(POMC)
MLF:
102442060
(POMC)
MDT:
132213890
(POMC)
PKL:
118717236
(POMC)
EFUS:
103305549
(POMC)
SHON:
119001436
(POMC)
AJM:
119050328
(POMC)
PDIC:
114500769
(POMC)
PHAS:
123822577
(POMC)
MMF:
118630978
(POMC)
PPAM:
129065100
(POMC)
HAI:
109392186
(POMC)
RFQ:
117033055
(POMC)
PALE:
102881636
(POMC)
PGIG:
120621544
(POMC)
PVP:
105289810
(POMC)
RAY:
107498502
(POMC)
MJV:
108391586
(POMC)
TOD:
119258707
(POMC)
SARA:
101546548
(POMC)
SETR:
126024045
(POMC)
LAV:
100669102
(POMC)
TMU:
101350203
DNM:
101413154
(POMC)
MDO:
554192
(POMC)
GAS:
123235003
(POMC)
SHR:
100925922
(POMC)
PCW:
110206520
(POMC)
TVP:
118844860
(POMC)
OAA:
100078749
(POMC)
GGA:
422011
(POMC)
PCOC:
116235624
(POMC)
MGP:
100540012
(POMC)
CJO:
107312350
(POMC)
TPAI:
128085898
(POMC)
LMUT:
125689818
(POMC)
NMEL:
110396265
(POMC)
APLA:
101790746
(POMC)
ACYG:
106038100
(POMC)
CATA:
118256555
(POMC)
AFUL:
116487794
(POMC)
LSR:
110477401
(POMC)
SCAN:
103824789
(POMC)
PMOA:
120504511
(POMC)
OTC:
121341322
(POMC)
PRUF:
121365254
(POMC)
FAB:
101806406
(POMC)
OMA:
130266958
(POMC)
PHI:
102112401
(POMC)
PMAJ:
107211483
(POMC)
CCAE:
111943219
(POMC)
ZLE:
135441552
135441556
ACHL:
103797412
(POMC)
SVG:
106864352
(POMC)
FPG:
101918972
(POMC)
FCH:
102058223
(POMC)
NNT:
104405822
(POMC)
SHAB:
115610053
(POMC)
ACUN:
113478748
(POMC)
TALA:
116964725
(POMC)
ACHC:
115351199
(POMC)
HLE:
104841479
(POMC)
AGEN:
126046394
GCL:
127014431
LDI:
104346466
(POMC)
MNB:
103782046
(POMC)
DPUB:
104306754
(POMC)
BRHI:
104498066
(POMC)
EGZ:
104132024
(POMC)
NNI:
104014712
(POMC)
PCRI:
104029261
(POMC)
AFOR:
103902404
(POMC)
FGA:
104080683
(POMC)
CLV:
102092785
(POMC)
MUI:
104536626
(POMC)
CUCA:
104061783
(POMC)
TEO:
104378198
(POMC)
OHA:
104336841
(POMC)
ACAR:
104525202
(POMC)
CPEA:
104392743
(POMC)
CVF:
104295676
(POMC)
RTD:
128907077
(POMC)
AAM:
106488015
(POMC)
AROW:
112966661
(POMC)
NPD:
112948766
(POMC)
DNE:
112984278
(POMC)
ASN:
102377619
(POMC)
AMJ:
102566274
(POMC)
CPOO:
109311542
(POMC)
PSS:
102461051
(POMC)
CMY:
102942257
(POMC)
CCAY:
125634741
(POMC)
DCC:
119853165
(POMC)
CPIC:
101945502
(POMC)
TST:
117874072
(POMC)
CABI:
116830867
(POMC)
MRV:
120401321
(POMC)
ACS:
100553085
(pomc)
ASAO:
132761646
(POMC)
PVT:
110069810
(POMC)
SUND:
121921212
(POMC)
PBI:
103068030
(POMC)
PMUR:
107291045
(POMC)
CTIG:
120309078
(POMC)
TSR:
106541774
(POMC)
PGUT:
117657098
(POMC)
APRI:
131188993
(POMC)
131188997
PTEX:
113452334
113452726
NSS:
113414584
(POMC)
VKO:
123033614
(POMC)
PMUA:
114594958
(POMC)
PRAF:
128411478
(POMC)
ZVI:
118082718
(POMC)
HCG:
128340127
(POMC)
GJA:
107110755
(POMC)
STOW:
125445064
(POMC)
EMC:
129331209
(POMC)
XLA:
373802
(pomc.S)
380532
(pomc.L)
XTR:
496777
(pomc)
NPR:
108799842
(POMC)
RTEM:
120936040
(POMC)
BBUF:
120997157
(POMC)
BGAR:
122936295
(POMC)
MUO:
115465148
(POMC)
GSH:
117356493
(POMC)
DRE:
100034412
(pomcb)
353221
(pomca)
SRX:
107726737
107733137
107743298
107752780
SANH:
107674088
107678841
107697155
107697779
SGH:
107549702
107592776
107594781
107603097
CCAR:
109047265
109056086
109063696
109076472
CAUA:
113060636
113076332
113092578
113117254
(pomc)
113120524
CGIB:
127938785
127976671
127983760
128031438
PTET:
122324667
(pomcb)
122362017
(pomca)
LROH:
127179916
(pomca)
127182822
(pomcb)
OMC:
131523306
(pomca)
131526924
(pomcb)
PPRM:
120482313
(pomca)
120493405
(pomcb)
RKG:
130076937
(pomca)
130103135
(pomcb)
MAMB:
125269085
(pomca)
125278424
(pomcb)
CIDE:
127498817
127502327
CERY:
137006616
(pomca)
137018533
(pomcb)
MASI:
127410093
127411032
127415695
127455019
TROS:
130560350
(pomca)
130565480
(pomcb)
TDW:
130434303
(pomcb)
130436622
(pomca)
MANU:
129417015
(pomca)
129429585
(pomcb)
IPU:
100304596
(pomca)
108257754
(pomcb)
IFU:
128601168
(pomcb)
128613156
(pomca)
PHYP:
113532263
113534037
(pomc)
SMEO:
124376707
(pomcb)
124390512
(pomca)
TFD:
113648241
(pomcb)
113651227
(pomca)
TVC:
132842277
(pomcb)
132852093
(pomca)
TRN:
134320158
(pomcb)
134324931
(pomca)
AMEX:
103022135
(pomca)
103035140
(pomcb)
CMAO:
118803179
(pomca)
118816182
(pomcb)
EEE:
113570090
113583668
(pomc)
CHAR:
105901586
105908246
105908249
(pomca)
TRU:
101064982
101072941
TFS:
130516256
130522226
TNG:
GSTEN00030372G001
LCO:
104921984
104939652
104939766
NCC:
104941507
104955029
104967799
TBEN:
117475883
117478166
(pomca)
117492085
CGOB:
115003530
115016181
PGEO:
117440129
117455378
(pomca)
GACU:
117533782
117559272
(pomca)
EMAC:
134874481
(pomca)
134876828
ELY:
117249986
117264099
117270585
EFO:
125884854
125896834
125904314
PLEP:
121955516
121964515
(pomca)
SLUC:
116044757
116055658
116066262
ECRA:
117941068
117957198
117961728
ESP:
116692391
116705856
PFLV:
114550915
114568187
114573418
GAT:
120808489
120827007
PPUG:
119194845
119219029
AFB:
129096924
129107359
129111661
CLUM:
117727499
117738801
117738881
PSWI:
130196468
(pomca)
130202533
MSAM:
119907947
119908822
119912427
SCHU:
122862948
122871981
CUD:
121506433
(pomca)
121521232
121523886
ALAT:
119012559
119015148
119017367
ASTR:
137591609
137613415
MZE:
101475601
101481156
101487793
(pomc)
ONL:
100704837
(pomc)
100706564
100708840
OAU:
116310658
116316662
116316682
(pomca)
OLA:
101156390
(pomc)
101164777
101168338
OML:
112156827
(pomca)
112158409
112162582
CSAI:
133425269
133464615
XMA:
102229500
102233792
102236646
XCO:
114140646
114155974
114158568
XHE:
116715727
116731359
116734026
PRET:
103457138
(pomc)
103457563
103472811
PFOR:
103138592
103149764
103150924
PLAI:
106950364
(pomc)
106955877
106957171
PMEI:
106905501
106919916
106924457
GAF:
122825296
122826967
(pomca)
122844119
PPRL:
129351154
129356862
129375969
CVG:
107083380
107084950
107096024
CTUL:
119785112
119795261
GMU:
124861481
124879197
124881661
NFU:
107377602
107384562
107394404
KMR:
108240084
108242478
108246358
ALIM:
106516918
106523603
106535720
NWH:
119418521
119418534
119425909
AOCE:
111577563
111580118
111584656
MCEP:
124998796
125000681
125019771
CSEM:
103380837
103389827
103393769
POV:
109636219
109646399
109648177
SSEN:
122761700
122784202
HHIP:
117758279
117771065
117773095
HSP:
118099236
118103571
118124652
PPLT:
128430933
128460374
128461504
SMAU:
118290649
118292284
118309681
(pomca)
LCF:
108873190
108873226
108885708
108887571
108895658
SDU:
111230638
111238516
111240052
SLAL:
111646907
111650570
111657888
111665689
XGL:
120789057
120798055
HCQ:
109509694
109518110
SSCV:
125988086
SBIA:
133497010
133510023
(pomca)
PEE:
133411166
(pomca)
133416734
PTAO:
133468087
133484359
(pomca)
BPEC:
110155782
110164031
MALB:
109954442
109955701
BSPL:
114849221
114851167
SJO:
128354302
128374363
128376972
SASA:
100169856
100510783
100510784
STRU:
115161912
115172963
115187348
OTW:
112236651
112253676
112256958
(pomca)
OMY:
100136771
(pomca)
100136772
118944361
(pomca)
OGO:
124001796
124019353
124046762
(pomca)
ONE:
115118699
115119580
115140459
OKI:
109866727
109881191
109882172
OKE:
118380390
118387016
127915800
(pomca)
SALP:
111972551
112076918
(pomc)
112077138
SNH:
120019514
120041614
120060135
CCLU:
121538749
121544567
121549265
ELS:
105009780
105031564
(pomc)
SFM:
108921182
108924014
PKI:
111833562
111841265
AANG:
118229386
(pomca)
LOC:
102689241
(pomc)
PSPA:
121316005
121317143
ARUT:
117403299
117411446
PSEX:
120526116
(pomca)
LCM:
102350115
(POMC)
CMK:
103190580
RTP:
109922269
(pomca)
CPLA:
122552537
(pomca)
HOC:
132819291
(pomca)
LERI:
129699832
(pomca)
PMRN:
103091808
103091817
(POM)
116942582
LRJ:
133347401
133352999
133353223
NVE:
5521605
» show all
Taxonomy
UniProt
Reference
PMID:
6308009
Authors
Uhler M, Herbert E, D'Eustachio P, Ruddle FD
Title
The mouse genome contains two nonallelic pro-opiomelanocortin genes.
Journal
J Biol Chem 258:9444-53 (1983)
Sequence
[mmu:
18976
]
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