KEGG ORTHOLOGY: K12496

ORTHOLOGY: K12496

Entry

K12496                      KO

Symbol

EGR2

Name

early growth response protein 2

Pathway

map04625

C-type lectin receptor signaling pathway

map05161

Hepatitis B

map05166

Human T-cell leukemia virus 1 infection

map05203

Viral carcinogenesis

Disease

H00264

Charcot-Marie-Tooth disease

H02357

Congenital hypomyelinating neuropathy

H02359

Dejerine-Sottas disease

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    K12496  EGR2; early growth response protein 2
09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K12496  EGR2; early growth response protein 2
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K12496  EGR2; early growth response protein 2
   05161 Hepatitis B
    K12496  EGR2; early growth response protein 2
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K12496  EGR2; early growth response protein 2
Transcription factors [BR:ko03000]
Eukaryotic type
  Zinc finger
   Cys2His2 SP/KLF family and related proteins
    K12496  EGR2; early growth response protein 2

Genes

HSA:	1959(EGR2)

PTR:	745846(EGR2)

PPS:	100990362(EGR2)

GGO:	101137152(EGR2)

PON:	100450873(EGR2)

PPYG:

129006569(EGR2)

NLE:	100581768(EGR2)

HMH:	116458500(EGR2)

SSYN:

129480542(EGR2)

MCC:	698132(EGR2)

MCF:	102115320(EGR2)

MTHB:

126962145

MNI:	105466162(EGR2)

CSAB:

103216128(EGR2)

CATY:

105581495(EGR2)

PANU:

101021894(EGR2)

TGE:	112631510(EGR2)

MLEU:

105527849(EGR2)

RRO:	104655652(EGR2)

RBB:	108533155(EGR2)

TFN:	117082348(EGR2)

PTEH:

111537959(EGR2)

CANG:

105513254(EGR2)

CJC:	100404818(EGR2)

SBQ:	101032312(EGR2)

CIMI:

108313780(EGR2)

ANAN:

105712641(EGR2)

CSYR:

103272751(EGR2)

MMUR:

105870252(EGR2)

LCAT:

123649935(EGR2)

PCOQ:

105821106(EGR2)

OGA:	100943294(EGR2)

MMU:	13654(Egr2)

MCAL:

110303857(Egr2)

MPAH:

110326823(Egr2)

RNO:	114090(Egr2)

MCOC:

116075163(Egr2)

ANU:	117724548(Egr2)

ASYL:

127669928(Egr2)

MUN:	110547601(Egr2)

CGE:	100770422(Egr2)

MAUA:

101834268(Egr2)

PROB:

127224065(Egr2)

PLEU:

114698523(Egr2)

PMAV:

102907288(Egr2)

MORG:

121450868(Egr2)

MFOT:

126502720

AAMP:

119823428(Egr2)

NGI:	103737476(Egr2)

HGL:	101712435(Egr2)

CPOC:

100721167(Egr2)

CCAN:

109700461(Egr2)

DORD:

105986276(Egr2)

DSP:	122122284(Egr2)

DMER:

138826057(Egr2)

PLOP:

125346366(Egr2)

NCAR:

124985001

MMMA:

107158232(Egr2)

ITI:	101961496(Egr2)

OCU:

100351345

OPI:	101531884(EGR2)

OCZ:	121153485(EGR2)

TUP:	102474116(EGR2)

GVR:	103607840(EGR2)

CFA:	479219(EGR2)

CLUD:

112651213(EGR2)

VVP:	112931060(EGR2)

VLG:	121486330(EGR2)

NPO:	129499229(EGR2)

AML:	100479556(EGR2)

UMR:	103667995 121101184

UAH:	113259091(EGR2)

UAR:	123783100(EGR2)

ELK:

111144964

LLV:

125085101

MPUF:

101681105(EGR2)

MNP:	132016253(EGR2)

MLK:	131828917(EGR2)

NVS:	122900713(EGR2)

ORO:	101372988(EGR2)

EJU:	114224777(EGR2)

ZCA:	113923927(EGR2)

MLX:	118019604 118020097

NSU:	110589200(EGR2)

LWW:	102731265(EGR2)

FCA:	101082520(EGR2)

PYU:	121036679(EGR2)

PCOO:

112854780(EGR2)

PBG:	122492798(EGR2)

PVIV:

125147416(EGR2)

LRUF:

124506841

LGF:	123576569(EGR2)

AJU:

106989877

PTG:	102967470(EGR2)

PPAD:

109264309(EGR2)

PUC:

125932658

PLEZ:

122202604(EGR2)

HHV:	120247450(EGR2)

BTA:	100297981(EGR2)

BOM:	102275328(EGR2)

BBUB:

102394072(EGR2)

BBIS:

105001233(EGR2)

CHX:	102174905(EGR2)

OAS:	101122407(EGR2)

BTAX:

128048574(EGR2)

CSUM:

138087628(EGR2)

ODA:	120865230(EGR2)

CCAD:

122446521(EGR2)

MREE:

136158094(EGR2)

OVR:	110138435(EGR2)

MBEZ:

129555800(EGR2)

SSC:	100038004(EGR2)

CFR:	102515722(EGR2)

CBAI:

105071294(EGR2)

CDK:	105093861(EGR2)

VPC:	102546004(EGR2)

BACU:

103018637(EGR2)

BMUS:

118882289(EGR2)

LVE:	103085295(EGR2)

OOR:	101273894(EGR2)

LALB:

132506877(EGR2)

GMF:	115847934(EGR2)

DDP:	132439463(EGR2)

DLE:	111167600(EGR2)

PCAD:

102984978(EGR2)

PSIU:

116741176(EGR2)

PPHC:

136136291(EGR2)

NASI:

112413294(EGR2)

ECB:	100062890(EGR2)

EPZ:	103548676(EGR2)

EAI:	106826178(EGR2)

MYB:	102250617(EGR2)

MYD:	102763960(EGR2)

MMYO:

118670048(EGR2)

MLF:	102418346(EGR2)

MDT:	132214929(EGR2)

MYUM:

139021947(EGR2)

PKL:	118719206(EGR2)

EFUS:

103289535(EGR2)

MNA:	107543279(EGR2)

DRO:	112305498(EGR2)

SHON:

118998495(EGR2)

AJM:	119055723(EGR2)

PDIC:

114498083(EGR2)

PHAS:

123820941(EGR2)

MMF:	118632339(EGR2)

PPAM:

129069795(EGR2)

HAI:	109380608(EGR2)

RFQ:	117035958(EGR2)

PALE:

102882726(EGR2)

PGIG:

120609416(EGR2)

PVP:	105298813(EGR2)

RAY:	107517963(EGR2)

MJV:	108392949(EGR2)

TOD:	119233522(EGR2)

SARA:

101538660(EGR2)

SFUM:

130017218(EGR2)

SETR:

126033633(EGR2)

LAV:	100665680(EGR2)

TMU:

101341962

ETF:	101651553(EGR2)

DNM:	101427150(EGR2)

MDO:	100017006(EGR2)

GAS:	123253967(EGR2)

SHR:	100923372(EGR2)

AFZ:

127552125

PCW:	110216430(EGR2)

TVP:	118829001(EGR2)

PBRV:

138172189(EGR2)

MLAO:

141520646(EGR2)

OAA:	114810106(EGR2)

TACU:

119925279(EGR2)

GGA:

101748577

PCOC:

116235107(EGR2)

CJO:	107315685(EGR2)

TPAI:

128077857(EGR2)

LMUT:

125693929(EGR2)

NMEL:

110399651(EGR2)

APLA:

113844391(EGR2)

ACYG:

136786331(EGR2)

CATA:

118243808(EGR2)

AFUL:

116491615(EGR2)

TGU:	100226024(EGR2)

LSR:	110473160(EGR2)

SCAN:

115485533

PMOA:

120507252(EGR2)

OTC:	121336186(EGR2)

PRUF:

121357288(EGR2)

ATRC:

139595452(EGR2)

FAB:	101808923(EGR2)

OMA:	130254770(EGR2)

PHI:	102106905(EGR2)

PMAJ:

107207125(EGR2)

CCW:	120410197(EGR2)

ACOE:

138112266(EGR2)

ETL:	114063904(EGR2)

ZLE:	135449527(EGR2)

SVG:	106856772(EGR2)

MMEA:

130574902(EGR2)

HRT:	120755943(EGR2)

SATI:

136364353(EGR2)

CFAI:

136294159(EGR2)

CCIC:

134046314(EGR2)

SHAB:

115608979(EGR2)

SURA:

141945605(EGR2)

TALA:

116961990(EGR2)

ACHC:

115348360(EGR2)

HLE:	104832010(EGR2)

AGEN:

126042501

HHAR:

128147235(EGR2)

GCL:

127017942

PPUS:

135176266(EGR2)

CBOR:

142084570(EGR2)

CBOY:

140655563(EGR2)

MAME:

142410958(EGR2)

CNIC:

135991005(EGR2)

CUCA:

128852734(EGR2)

GAME:

129208606(EGR2)

RTD:	128911449(EGR2)

CRID:

134517969(EGR2)

LMIC:

141745413(EGR2)

AROW:

112968081(EGR2)

NPD:	112950462(EGR2)

ASN:	102388844(EGR2)

AMJ:	102566870(EGR2)

CPOO:

109312433(EGR2)

GGN:

109290920

PSS:	102459517(EGR2)

CIZ:	142016065(EGR2)

CMY:	102941019(EGR2)

CCAY:

125639854(EGR2)

DCC:	119859067(EGR2)

CPIC:

101931400(EGR2)

TST:	117881057(EGR2)

CABI:

116822444(EGR2)

MRV:	120369370(EGR2)

ACS:	100565582(egr2)

ASAO:

132769923(EGR2)

SUND:

121924867(EGR2)

PMUR:

107287910(EGR2)

CTIG:

120306408(EGR2)

TSR:	106541572(EGR2)

PGUT:

117676079(EGR2)

PCAE:

139318340(EGR2)

APRI:

131200827(EGR2)

PTEX:

113453545 113453546

NSS:	113428204 113428206

VKO:	123018252(EGR2)

PMUA:

114597169(EGR2)

PRAF:

128413884(EGR2)

ZVI:	118096465(EGR2)

HCG:	128348903(EGR2)

GJA:	107112663(EGR2)

STOW:

125437979(EGR2)

EMC:	129332633(EGR2)

XLA:	378520(egr2.L)

XTR:	100101746(egr2)

NPR:	108804778(EGR2)

RTEM:

120947051(EGR2)

ACAT:

141105977(EGR2)

PADS:

140339587(EGR2)

BBUF:

121003958(EGR2)

BGAR:

122940781(EGR2)

DTC:	141051359(EGR2)

PWL:	138300964(EGR2)

MUO:	115470165(EGR2)

GSH:	117358803(EGR2)

DRE:	30190(egr2b) 368241(egr2a)

SRX:	107719319 107732758 107739063 107745678

SANH:

107653961 107683002 107703567

SGH:	107561671 107586831 107593522 107596611 107596614

CCAR:

109052667 109100038(egr2b) 122140184 122148199

CAUA:

113056331 113060562 113111926 113117098

CGIB:

127933505 127968844 127976541 128012882 128024983

PTET:

122355102(egr2b) 122362052(egr2a)

LROH:

127173733(egr2b) 127179297(egr2a)

GRF:	141296096(egr2a) 141298046(egr2b)

OMC:	131523727(egr2a) 131551174(egr2b)

PPRM:

120464008(egr2b) 120475814(egr2a)

RKG:	130080510(egr2b) 130088323(egr2a)

MAMB:

125255765(egr2b) 125268986(egr2a)

CIDE:

127498233 127523888

CERY:

137006427(egr2a) 137007922(egr2b)

MASI:

127411336 127423395 127426748 127454874

TROS:

130560008(egr2a) 130569122(egr2b)

TDW:	130437181(egr2a) 130438741(egr2b)

MANU:

129418214 129421365(egr2b) 141365332

PDAB:

135734742(egr2b) 135778137(egr2a)

IPU:	108269483(egr2a) 108273427(egr2b)

IFU:	128612396(egr2a) 128617488(egr2b)

PHYP:

113527547(egr2) 113538744

SMEO:

124388419(egr2b) 124390430(egr2a)

TFD:	113649371(egr2b) 113659784(egr2a)

TVC:	132841614(egr2b) 132852610(egr2a)

CGAR:

128535959(egr2a) 128540839(egr2b)

NGRA:

132893891(egr2a) 132897681(egr2b)

TRN:	134321676(egr2b) 134325691(egr2a)

AMEX:

103032442(egr2a) 103046494(egr2b)

CMAO:

118809192(egr2b) 118824092(egr2a)

EEE:	113583332 113584638(egr2)

CHAR:

105910525(egr2b)

SPIL:

134069935(egr2b)

ASAD:

121700114(egr2b)

TRU:	101071500 101076320(egr2)

TFS:	130533965(egr2a) 130538879(egr2b)

TNG:	GSTEN00002141G001 GSTEN00008478G001 GSTEN00034581G001

LCO:	104924319(egr2) 104928251

NCC:	104951088 104965502(egr2)

TBEN:

117473396(egr2b) 117487232

CGOB:

115005542 115024692(egr2)

PGEO:

117460020 117464981(egr2b)

GACU:

117536266(egr2b) 117562569

EMAC:

134858852 134870440(egr2b)

ELY:	117246978(egr2b) 117248103

EFO:	125881005(egr2b) 125903930

PLEP:

121954803 121958864(egr2b)

SLUC:

116056401 116067557(egr2b)

ECRA:

117937231(egr2b)

ESP:	116671528(egr2) 116679138

PFLV:

114548289(egr2) 114572355

GAT:	120819818(egr2b) 120820281

PPUG:

119212443(egr2b) 119213894

AFB:	129092708 129093568(egr2b)

CLUM:

117743637(egr2a) 117749064(egr2b)

PSWI:

130203666(egr2b) 130206902(egr2a)

CANA:

137779478 137789734(egr2b)

CVE:

137888450

MSAM:

119911447 119912147 119916477(egr2b)

SCHU:

122867969(egr2b) 122884561

CUD:	121511417 121527949(egr2b)

SPUL:

138588689 138593414(egr2b)

LMIX:

132955611(egr2b) 132975674

HTC:	141785286(egr2b) 141795029

ALAT:

119009274(egr2b) 119033629

ASTR:

137588390(egr2b) 137604020

MZE:	101466115 101471055(egr2)

ONL:	100694363(egr2) 100712147

OAU:	116319968(egr2b) 116335522

OLA:	101164744 101170128(egr2)

OML:	112162100(egr2a) 112162326(egr2b)

CSAI:

133419743 133464106

XMA:	102220095 102225567 102238239(egr2)

XCO:	114138050 114151636(egr2)

XHE:	116712925 116713617 116727739(egr2)

PRET:

103477379 103482204(egr2)

PFOR:

103131659(egr2) 103149026

PLAI:

106939642(egr2) 106959983

PMEI:

106909232(egr2) 106916153

GAF:	122823397(egr2b) 122842811(egr2a)

PPRL:

129352227(egr2b) 129355197

CVG:	107087633(egr2) 107097158

CTUL:

119787373 119795748

GMU:	124858909 124875431(egr2b)

NFU:	107373912(egr2) 107396841

KMR:	108245162(egr2b) 108246627

ALIM:

106527986 106534740(egr2)

NWH:	119419736 119423327(egr2b)

AOCE:

111562821 111569202(egr2b)

EJA:	138209759(egr2b) 138215163

BFRE:

138626827(egr2b) 138627148

MCEP:

125018597 125022563(egr2b)

CSEM:

103381676(egr2) 103387034

POV:	109626659(egr2)

SSEN:

122760051(egr2b) 122763064(egr2a)

SSOE:

131448568(egr2b) 131474429(egr2a)

HHIP:

117752391(egr2b) 117776046

HSP:	118101137(egr2b) 118119293

PPLT:

128426818(egr2b) 128453253

SMAU:

118283766 118287986(egr2b)

LCF:	108872891 108876762(egr2b)

SDU:	111224243 111237096(egr2)

SLAL:

111653562 111664326(egr2)

XGL:	120794399(egr2b) 120796541(egr2a)

HCQ:	109510060 109529317(egr2)

SSCV:

125978891 137839545(egr2b)

SBIA:

133495671(egr2b) 133509705(egr2a)

PEE:	133395279(egr2b)

PTAO:

133469396(egr2b) 133485889(egr2a)

BPEC:

110153149 110154203(egr2)

ENY:	140351616 140369146(egr2b)

MALB:

109953419 109966664(egr2)

BSPL:

114846448(egr2b) 114870684

SJO:	128354668 128381318(egr2b)

SSCO:

133976788 134003459(egr2b)

TTY:	137172289(egr2b) 137197408(egr2a)

GMH:	115531668(egr2) 115559709

SASA:

100194495(krox20) 106577138 106592202 106598760 106607870

STRU:

115153287 115189546 115189547 115193670

OTW:	112240378(egr2b) 112251986 112253108

OMY:	110511819 110512060 110529928

OGO:	124017091 124023812 124027221 124042247

ONE:	115112686 115116062(egr2) 115136512

OKI:	109883662 109890004 109898875 116362193

OKE:	118361238 118369794 118381084

OMM:	135511098 135511389 135529409

OCLA:

139381511 139412516 139418251

SALP:

111951729 111978614 112078272

SNH:	120017950 120038387 120039585

SFON:

129835963 129846602 129847801 129858245

CCLU:

121544989 121553523 121584720

ELS:	105006249 105026307(egr2) 109615845

OEP:	134022525 134031796(egr2b)

SFM:	108932786 108939575(egr2)

PKI:	111853677(egr2)

AANG:

118218262(egr2a) 118219728(egr2b)

AROT:

135244694(egr2a) 135247049(egr2b)

CCOG:

133118520(egr2a) 133122286(egr2b)

LOC:	102688444(egr2)

PSPA:

121321537 121325169

ARUT:

117416133 117418074

PSEX:

120520346(egr2b)

LCM:	102348834(EGR2)

CMK:	103181027(egr2b)

RTP:	109918799(egr2b)

CPLA:

122560949(egr2b)

CPUN:

140463641(egr2b)

HOC:	132826414(egr2b)

SCAU:

119950761(egr2b)

LERI:

129704225(egr2b)

HAKA:

140715284(egr2b)

BIM:

ZCE:

HAW:

TNL:

PVM:

EGL:

Reference

PMID:17938205

Authors

Dillon RL, Brown ST, Ling C, Shioda T, Muller WJ

Title

An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer.

Journal

Mol Cell Biol 27:8648-57 (2007)
DOI:10.1128/MCB.00866-07

Reference

PMID:3140236

Authors

Joseph LJ, Le Beau MM, Jamieson GA Jr, Acharya S, Shows TB, Rowley JD, Sukhatme VP

Title

Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structure.

Journal

Proc Natl Acad Sci U S A 85:7164-8 (1988)
DOI:10.1073/pnas.85.19.7164

Sequence

[hsa:1959]

LinkDB

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