KEGG ORTHOLOGY: K15610

ORTHOLOGY: K15610

Entry

K15610                      KO

Symbol

PBX3

Name

pre-B-cell leukemia transcription factor 3

Pathway

map05202

Transcriptional misregulation in cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K15610  PBX3; pre-B-cell leukemia transcription factor 3
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K15610  PBX3; pre-B-cell leukemia transcription factor 3
Transcription factors [BR:ko03000]
Eukaryotic type
  Helix-turn-helix
   Homeo domain TALE
    K15610  PBX3; pre-B-cell leukemia transcription factor 3

Genes

HSA:	5090(PBX3)

PTR:	464737(PBX3)

PPS:	100985710(PBX3)

GGO:	101131267(PBX3)

PON:	100459300(PBX3)

PPYG:

129043762(PBX3)

NLE:	100602957(PBX3)

HMH:	116475666(PBX3)

SSYN:

129478880(PBX3)

MCC:	711691(PBX3)

MCF:	102136120(PBX3)

MTHB:

126937192

MNI:	105463927(PBX3)

CSAB:

103239865(PBX3)

CATY:

105576274(PBX3)

PANU:

101018168(PBX3)

TGE:	112608404(PBX3)

MLEU:

105545673(PBX3)

RRO:	104664387(PBX3)

RBB:	108531348(PBX3)

TFN:	117071347(PBX3)

PTEH:

111545926(PBX3)

CANG:

105504092(PBX3)

CJC:	100391273(PBX3)

SBQ:	101047852(PBX3)

CIMI:

108318231(PBX3)

ANAN:

105721193(PBX3)

CSYR:

103262060(PBX3)

MMUR:

105875195(PBX3)

LCAT:

123645631(PBX3)

ERUF:

138387576(PBX3)

PCOQ:

105806665(PBX3)

OGA:	100948268(PBX3)

MMU:	18516(Pbx3)

MCAL:

110311652(Pbx3)

MPAH:

110317813(Pbx3)

RNO:	311876(Pbx3)

MCOC:

116090040(Pbx3)

ANU:	117703090(Pbx3)

ASYL:

127685266(Pbx3)

MUN:	110553677(Pbx3)

CGE:	100758595(Pbx3)

MAUA:

101844760(Pbx3)

PROB:

127222801(Pbx3)

PLEU:

114704688(Pbx3)

PMAV:

102913958(Pbx3)

MORG:

121463054(Pbx3)

MFOT:

126513353

AAMP:

119818775(Pbx3)

CNL:	130864929(Pbx3)

NGI:	103727072(Pbx3)

HGL:	101710079(Pbx3)

CPOC:

100729729(Pbx3)

CCAN:

109689935

DORD:

105989446(Pbx3)

DSP:	122109025(Pbx3)

DMER:

138821457(Pbx3)

PLOP:

125349060(Pbx3)

NCAR:

124964287

MMMA:

107152084(Pbx3)

ITI:	101976707(Pbx3)

OCU:

100337840

OPI:	101536203(PBX3)

OCZ:	121144693(PBX3)

TUP:	102481697(PBX3)

GVR:

103598905

CFA:	480723(PBX3)

CLUD:

112677214(PBX3)

VVP:	112927886(PBX3)

VLG:	121473462(PBX3)

NPO:	129514981(PBX3)

AML:	100482077(PBX3)

UMR:	103670319(PBX3)

UAH:	113266415(PBX3)

UAR:	123787967(PBX3)

ELK:

111145820

LLV:

125083424

MPUF:

101688483(PBX3)

MNP:	132024417(PBX3)

MLK:	131812037(PBX3)

NVS:	122917244(PBX3)

ORO:	101378682(PBX3)

EJU:	114212868(PBX3)

ZCA:	113934999(PBX3)

MLX:	118017674(PBX3)

MANO:

123849262(PBX3)

NSU:	110581402(PBX3)

LWW:	102751070(PBX3)

FCA:	101085840(PBX3)

PYU:	121035000(PBX3)

PCOO:

112871562(PBX3)

PBG:	122474884(PBX3)

PVIV:

125150325(PBX3)

LRUF:

124504208

LGF:	123593743(PBX3)

AJU:

106965453

PTG:	102956616(PBX3)

PPAD:

109250163(PBX3)

PUC:

125927523

PLEZ:

122205621(PBX3)

HHV:	120223016 120236273(PBX3)

CCRU:

144235057(PBX3)

BTA:	539222(PBX3)

BOM:	102281798(PBX3)

BIU:	109566471(PBX3)

BBUB:

102407943(PBX3)

BKE:	129623553(PBX3)

BBIS:

104991550(PBX3)

CHX:	102187055(PBX3)

OAS:	101105732(PBX3)

BTAX:

128056295(PBX3)

CSUM:

138073087(PBX3)

ODA:	120851999(PBX3)

CCAD:

122442165(PBX3)

MREE:

136163774(PBX3)

OVR:	110125442(PBX3)

MBEZ:

129539011(PBX3)

SSC:	100152438(PBX3)

CFR:	102513840(PBX3)

CBAI:

105069902(PBX3)

CDK:	105092621(PBX3)

VPC:	102530285(PBX3)

BACU:

103017157(PBX3)

BMUS:

118897365(PBX3)

LVE:	103076262(PBX3)

OOR:	101287212(PBX3)

LALB:

132523358(PBX3)

GMF:	115854472(PBX3)

DDP:	132427066(PBX3)

DLE:	111177214(PBX3)

PCAD:

102996238(PBX3)

PSIU:

116755623(PBX3)

PPHC:

136124154(PBX3)

NASI:

112411455(PBX3)

ECB:	100070756(PBX3)

EPZ:	103552122(PBX3)

EAI:	106830830(PBX3)

MYB:	102248596(PBX3)

MYD:	102762832(PBX3)

MMYO:

118667054(PBX3)

MLF:	102429725(PBX3)

MDT:	132212392(PBX3)

MYUM:

139020772(PBX3)

PKL:	118704417(PBX3) 118727940

EFUS:

103298520(PBX3)

MNA:	107535490(PBX3)

DRO:	112306210(PBX3)

SHON:

118980069(PBX3)

AJM:	119060279(PBX3)

PDIC:

114493015(PBX3)

PHAS:

123823582(PBX3)

MMF:	118629878(PBX3)

PPAM:

129079265(PBX3)

HAI:	109379597(PBX3)

RFQ:	117032271(PBX3)

PALE:

102897051(PBX3)

PGIG:

120601717(PBX3)

PVP:	105294853(PBX3)

RAY:	107506631(PBX3)

MJV:	108396093(PBX3)

TOD:	119232883(PBX3)

SARA:

101544708(PBX3)

SFUM:

130042718 130045750

SETR:

126009632(PBX3)

LAV:	100663220(PBX3)

TMU:

101342080

ETF:	101650486(PBX3)

DNM:	101447994(PBX3)

MDO:	100019889(PBX3)

GAS:	123237355(PBX3)

SHR:	100924707(PBX3)

AFZ:

127550578

PCW:	110194978(PBX3)

TVP:	118844479(PBX3)

PBRV:

138157187(PBX3)

MLAO:

141505605(PBX3)

OAA:	100077727(PBX3)

TACU:

119927020(PBX3)

GGA:	417093(PBX3)

PCOC:

116234402(PBX3)

MGP:	100539165(PBX3)

CJO:	107321934(PBX3)

TPAI:

128073087(PBX3)

LMUT:

125702751(PBX3)

NMEL:

110406920(PBX3)

APLA:

101799200(PBX3)

AACU:

137842747(PBX3)

OJA:	118175314(PBX3)

ACYG:

106040701(PBX3)

CATA:

118252236(PBX3)

AFUL:

116496762(PBX3)

TGU:	100222055(PBX3)

LSR:	110477684(PBX3)

VMC:	128817677(PBX3)

SCAN:

103818915(PBX3)

PMOA:

120512349(PBX3)

OTC:	121337055(PBX3)

PRUF:

121362437(PBX3)

ATRC:

139603431(PBX3)

MATE:

118693257(PBX3)

GFR:	102035681(PBX3)

FAB:	101812125(PBX3)

OMA:	130260104(PBX3)

PHI:	102105082(PBX3)

PMAJ:

107199129 107211990(PBX3)

CCAE:

111937132(PBX3)

CCW:

104688521

CBRC:

103623092(PBX3)

ACOE:

138119527(PBX3)

ETL:	114062000(PBX3)

ZAB:	102066216(PBX3)

ZLE:	135454867(PBX3)

ACHL:

103810784

SVG:	106855395(PBX3)

MMEA:

130586687

HRT:	120761749(PBX3)

SATI:

136369877

CFAI:

136299513(PBX3)

CCIC:

134051583(PBX3)

FPG:	101911311(PBX3)

FCH:	102059573(PBX3)

NNT:

104408860

SHAB:

115617158(PBX3)

ACUN:

113486480(PBX3)

ANOC:

141968583(PBX3)

SURA:

141952894(PBX3)

TALA:

116964983(PBX3)

ACHC:

115334863(PBX3)

HLE:	104831115(PBX3)

AGEN:

126051866

HHAR:

128154121(PBX3)

BBUT:

142043937(PBX3)

GCL:

127023581

DPUB:

104306513(PBX3)

PPUS:

135190244(PBX3)

EGZ:	104134071(PBX3)

NNI:	104023332(PBX3)

PARX:

142065872(PBX3)

PADL:

103925690(PBX3)

AFOR:

103899609(PBX3)

CBOR:

142091496(PBX3)

CBOY:

140661222(PBX3)

MAME:

142418267(PBX3)

CLV:	102089709(PBX3)

CNIC:

135996418(PBX3)

MUI:	104537760(PBX3)

EHS:

104511170

CUCA:

104066981(PBX3)

GAME:

129215494(PBX3)

OHA:

104333793

ACAR:

104521420

CPEA:

104389866(PBX3)

CVF:	104292937(PBX3)

RTD:	128917447(PBX3)

CRID:

134523948(PBX3)

LMIC:

141751444(PBX3)

NARQ:

141473520(PBX3)

AAM:	106495034(PBX3)

AROW:

112977752(PBX3)

NPD:	112956035(PBX3)

TGT:	104568649(PBX3)

DNE:	112983632(PBX3)

SCAM:

104145874(PBX3)

ASN:	102372121(PBX3)

AMJ:	102559278(PBX3)

CPOO:

109314083(PBX3)

GGN:	109293098(PBX3)

PSS:	102461873(PBX3)

CIZ:	142023895(PBX3)

CMY:	102939653(PBX3)

CCAY:

125623512(PBX3)

LKP:	140899185(PBX3)

NDS:	142000106(PBX3)

DCC:	119844230(PBX3)

CPIC:

101942947(PBX3)

TST:	117889387(PBX3)

EOB:	135891238(PBX3)

CABI:

116818394(PBX3)

MRV:	120386861(PBX3)

ACS:	100552418 100563692

ASAO:

132763690(PBX3)

PVT:	110082920(PBX3)

SUND:

121937105(PBX3)

PBI:	103055896(PBX3)

PMUR:

107291878(PBX3)

CTIG:

120298887(PBX3)

TSR:	106539945 106544298

PCAE:

139325618(PBX3)

APRI:

131185962(PBX3)

PTEX:

113444040(PBX3)

NSS:	113426166(PBX3)

VKO:	123028387(PBX3)

PMUA:

114589579(PBX3)

PRAF:

128406735(PBX3)

ZVI:	118083880(PBX3)

HCG:	128338919(PBX3)

GJA:	107122926(PBX3)

STOW:

125441719(PBX3)

EMC:	129342054(PBX3)

XLA:	108698242 108700014(pbx3.S)

XTR:	100495648(pbx3)

NPR:	108784472(PBX3)

RTEM:

120913219

ACAT:

141108581(PBX3)

PADS:

140343299(PBX3)

BBUF:

121009501(PBX3)

BGAR:

122946267(PBX3)

DTC:	141101596(PBX3)

HSQ:	130290269(PBX3)

PCOB:

134948676(PBX3)

PWL:	138301360(PBX3)

MUO:	115472912(PBX3)

GSH:	117367503(PBX3)

DRE:	387532(pbx3a) 58140(pbx3b)

SRX:	107715538 107723227 107725095 107753156

SANH:

107654303 107659601(pbx3) 107668307 107669256

SGH:	107550583 107555108 107557570 107591489

CCAR:

109058322 109080555 109084756 109094829(pbx3b)

CAUA:

113068013 113073306 113073604 113096321 113107279

CGIB:

127945984 127957137 127963536 128014866 128018487

PTET:

122344747(pbx3a) 122350976(pbx3b) 122351126

LROH:

127165471(pbx3a) 127169112(pbx3b)

GRF:	141334655(pbx3a) 141335363

OMC:	131540930(pbx3a) 131545499(pbx3b)

PPRM:

120465294(pbx3a) 120485376(pbx3b)

RKG:	130072383(pbx3b) 130078564(pbx3a)

MAMB:

125266910(pbx3a) 125279967(pbx3b)

CIDE:

127512776 127517241

CERY:

137026534(pbx3b) 137034228(pbx3a)

MASI:

127414770 127423457 127424143 127440063

TROS:

130565578(pbx3a) 130568311(pbx3b)

TDW:	130407163(pbx3b) 130419308(pbx3a)

MANU:

129414055(pbx3b) 129439482(pbx3a)

PDAB:

135729565(pbx3b) 135732827(pbx3a)

IPU:	108265883(pbx3b)

IFU:	128607695(pbx3b)

PHYP:

113533603(pbx3)

SMEO:

124400156(pbx3b)

TFD:	113658507(pbx3b)

TVC:	132853974(pbx3b)

CGAR:

128530359(pbx3b)

NGRA:

132892490(pbx3b)

TRN:	134317846(pbx3b)

AMEX:

103029164(pbx3b) 103031528(pbx3a)

CMAO:

118813343(pbx3b) 118814389(pbx3a)

EEE:	113577278(pbx3)

CHAR:

105902509(pbx3a) 105905308(pbx3b)

SPIL:

134089641 134101427(pbx3a)

ASAD:

121680761(pbx3a) 121716137(pbx3b)

TRU:	101065377(pbx3)

TFS:	130526016(pbx3b)

TNG:	GSTEN00007338G001

LCO:	104924536(pbx3) 104934745

NCC:

104950955

TBEN:

117472451(pbx3b)

CGOB:

115013436(pbx3)

PGEO:

117451862(pbx3b)

GACU:

117543984(pbx3b)

EMAC:

134872942(pbx3b)

ELY:	117252512(pbx3b)

EFO:	125891023(pbx3b)

PLEP:

121944805(pbx3b)

SLUC:

116050536(pbx3b)

ECRA:

117944857(pbx3b)

ESP:	116689937(pbx3)

PFLV:

114555597(pbx3)

GAT:	120830867(pbx3b)

PPUG:

119224986(pbx3b)

AFB:	129101231(pbx3b)

CLUM:

117736423(pbx3b)

PSWI:

130196230(pbx3b)

CANA:

137778881(pbx3b)

CVE:	137867358(pbx3b)

MSAM:

119892144(pbx3b)

SCHU:

122876390(pbx3b)

EARM:

139283889(pbx3b) 139301686

CUD:	121510524(pbx3b)

SPUL:

138605045 138610390(pbx3b)

LMIX:

132973962(pbx3b) 132992529

HTC:	141790528(pbx3b)

ALAT:

119020195(pbx3b)

ASTR:

137593041

PKLU:

139203548(pbx3b) 139218747

MZE:	101481326(pbx3)

ONL:	100695477(pbx3)

OAU:	116322956(pbx3b)

OLA:	101159358(pbx3)

OML:	112148326(pbx3b)

CSAI:

133451587(pbx3b)

XMA:	102224344(pbx3)

XCO:	114154937(pbx3)

XHE:	116729909(pbx3)

PRET:

103470618(pbx3)

PFOR:

103146885(pbx3)

PLAI:

106953913

PMEI:

106929815(pbx3)

GAF:	122827796(pbx3b)

PPRL:

129373037(pbx3b)

CVG:	107095938(pbx3)

CTUL:

119785135(pbx3b)

GMU:	124877802(pbx3b)

NFU:	107393644(pbx3)

KMR:	108236549(pbx3b)

ALIM:

106516695(pbx3)

NWH:	119414052(pbx3b)

AOCE:

111585816(pbx3b)

EJA:	138215970(pbx3b)

BFRE:

138621533(pbx3b)

MCEP:

124996239 125012352(pbx3b)

POV:	109633650 109646060

SSEN:

122769340(pbx3b)

SSOE:

131463740(pbx3b)

HHIP:

117768036(pbx3b)

HSP:	118115679(pbx3b)

PPLT:

128438322(pbx3b)

SMAU:

118314384(pbx3b)

LCF:	108878619(pbx3b)

SDU:	111227957(pbx3)

SLAL:

111645056(pbx3)

XGL:	120805495(pbx3b)

HCQ:	109511642(pbx3)

SSCV:

125993589(pbx3b)

SBIA:

133499337(pbx3b)

PEE:	133399674(pbx3b)

PTAO:

133475617(pbx3b)

BPEC:

110169901(pbx3)

ENY:	140347627(pbx3b)

MALB:

109954915(pbx3)

BSPL:

114861554(pbx3b)

SJO:	128365315(pbx3b) 128380061

SSCO:

133979124(pbx3b) 133994913

TTY:	137171060 137193630(pbx3b)

GMH:

115545826

SASA:

106564174 106571753(pbx3) 106579892 106585542

STRU:

115160135 115164585 115182079 115200060

OTW:	112248426(pbx3b) 112262973 121840214

OMY:	110523137 110525603(pbx3b) 110535969

OGO:	123989536 124034360 124036254

ONE:	115111543 115126271 115139982

OKI:	109878924 109895844 109905034

OKE:	118358283 118393148(pbx3b)

OMM:	135514160 135532233 135532260 135540826(pbx3b)

OCLA:

139389592 139408284 139412000

SALP:

111957780 111974815 112070824

SNH:	120038404 120054569 120063199

SFON:

129819049 129826244 129853503

CCLU:

121530842 121581927 121584791

ELS:	105007317(pbx3) 105024007

OEP:	134012049(pbx3b) 134038442

SFM:	108922599 108937967

PKI:	111833131 111858755(pbx3)

AANG:

118206602(pbx3b) 118212568

AROT:

135240042 135265118(pbx3b)

CCOG:

133140298(pbx3b) 133141925

LOC:	102694639(pbx3)

PSPA:

121306695(pbx3b)

ARUT:

117396957 117962282

PSEX:

120536084

LCM:	102358815(PBX3) 102362840

CMK:	103189187(pbx4) 103189192

RTP:

CPLA:

CPUN:

HOC:

SCAU:

STOZ:

140399178(pbx3b)

LERI:

129711850(pbx3b)

HAKA:

140731181 140740180(pbx4)

SCLV:

CLEP:

SPU:

LPIC:

LVG:

AJJ:

ARUN:

SKO:	100302728(pbx)

NVI:

100123137

LGI:	LOTGIDRAFT_92730

BGT:

EGL:

RES:

Reference

PMID:1682799

Authors

Monica K, Galili N, Nourse J, Saltman D, Cleary ML

Title

PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1.

Journal

Mol Cell Biol 11:6149-57 (1991)
DOI:10.1128/mcb.11.12.6149

Sequence

[hsa:5090]

Reference

PMID:18033668

Authors

Laurent A, Bihan R, Omilli F, Deschamps S, Pellerin I

Title

PBX proteins: much more than Hox cofactors.

Journal

Int J Dev Biol 52:9-20 (2008)
DOI:10.1387/ijdb.072304al

LinkDB

DBGET integrated database retrieval system