KEGG ORTHOLOGY: K22863

ORTHOLOGY: K22863

Entry

K22863                      KO

Symbol

WDPCP, CPLANE5

Name

WD repeat-containing and planar cell polarity effector protein

Disease

H00418

Bardet-Biedl syndrome

H02455

Congenital heart defects, hamartomas of tongue, and polysyndactyly

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K22863  WDPCP, CPLANE5; WD repeat-containing and planar cell polarity effector protein
Cilium and associated proteins [BR:ko03037]
Primary cilia and associated proteins
  Ciliogenesis and planar polarity effectors (CPLANE) complex
   K22863  WDPCP, CPLANE5; WD repeat-containing and planar cell polarity effector protein

Genes

HSA:	51057(WDPCP)

PTR:	459270(WDPCP)

PPS:	100977442(WDPCP)

GGO:	101134414(WDPCP)

PON:	100459722(WDPCP)

PPYG:

129030150(WDPCP)

NLE:	100581349(WDPCP)

HMH:	116483799(WDPCP)

SSYN:

129461998(WDPCP)

MCC:	694431(WDPCP)

MCF:	102131904(WDPCP)

MTHB:

126933596

MNI:	105465131(WDPCP)

CSAB:

103220174(WDPCP)

CATY:

105576457(WDPCP)

PANU:

101019694(WDPCP)

TGE:	112604711(WDPCP)

MLEU:

105544717(WDPCP)

RRO:	104669215(WDPCP)

RBB:	108517120(WDPCP)

TFN:	117099717(WDPCP)

PTEH:

111550615(WDPCP)

CANG:

105513818

CJC:	100397933(WDPCP)

SBQ:	101041058(WDPCP)

CIMI:

108299718

ANAN:

105734352(WDPCP)

CSYR:

103262066(WDPCP)

MMUR:

105871516(WDPCP)

LCAT:

123636962

PCOQ:

105806152(WDPCP)

OGA:	100944286(WDPCP)

MMU:	216560(Wdpcp)

MCAL:

110304224(Wdpcp)

MPAH:

110330511(Wdpcp)

RNO:	305552(Wdpcp)

MCOC:

116071125(Wdpcp)

ANU:	117712517(Wdpcp)

ASYL:

127696078(Wdpcp)

MUN:	110540011(Wdpcp)

CGE:	100769859(Wdpcp)

MAUA:

101824868

PROB:

127233898(Wdpcp)

PLEU:

MORG:

MFOT:

AAMP:

NGI:	103748090(Wdpcp)

HGL:	101702653(Wdpcp)

CPOC:

106027162(Wdpcp)

CCAN:

109685018(Wdpcp)

DORD:

105990195(Wdpcp)

DSP:

DMER:

PLOP:

NCAR:

MMMA:

ITI:

OCU:

OPI:

OCZ:

TUP:	102500860(WDPCP)

CFA:	474613(WDPCP)

CLUD:

112673404

VVP:	112915290(WDPCP)

VLG:

121490978

NPO:	129512192(WDPCP)

AML:	100484777(WDPCP)

UMR:

103671314

UAH:	113245028(WDPCP)

UAR:

123785977

ELK:

111148096

LLV:

125108494

MPUF:

101686034(WDPCP)

MNP:	132021510(WDPCP)

MLK:	131840192(WDPCP)

NVS:

122916524

ORO:	101362423(WDPCP)

EJU:	114198316(WDPCP)

ZCA:

113937823

MLX:	118008067(WDPCP)

NSU:

110588787

LWW:	102746263(WDPCP)

FCA:	101085794(WDPCP)

PYU:

121019113

PCOO:

112869658(WDPCP)

PBG:

122496902

PVIV:

125161935(WDPCP)

LRUF:

124503919

LGF:

123580849

AJU:

106973478

PTG:	102951328(WDPCP)

PPAD:

109258082(WDPCP)

PUC:

125936261

PLEZ:

122216109

HHV:

120239070

BTA:	527992(WDPCP)

BOM:	102270887(WDPCP)

BIU:	109566203(WDPCP)

BBUB:

102389627

BBIS:

105005336(WDPCP)

CHX:	102176430(WDPCP)

OAS:	101119202(WDPCP)

BTAX:

128055312(WDPCP)

CSUM:

138074669(WDPCP)

ODA:

120851330

CCAD:

122441822

MREE:

136164297(WDPCP)

OVR:	110124460(WDPCP)

MBEZ:

129540020(WDPCP)

SSC:	106507382(WDPCP)

CFR:	102518155(WDPCP)

CBAI:

105066545(WDPCP)

CDK:	105101815(WDPCP)

VPC:	102531515(WDPCP)

BACU:

103018799(WDPCP)

BMUS:

118906362

LVE:	103086673(WDPCP)

OOR:	101275471(WDPCP)

LALB:

132531260(WDPCP)

GMF:	115864174(WDPCP)

DDP:	132435363(WDPCP)

DLE:	111186589(WDPCP)

PCAD:

102978973(WDPCP)

PSIU:

116764430(WDPCP)

PPHC:

136133567(WDPCP)

NASI:

112404852(WDPCP)

ECB:	100063987(WDPCP)

EPZ:	103561032(WDPCP)

EAI:

106828282

MYB:	102253268(WDPCP)

MYD:	102758814(WDPCP)

MMYO:

118668947

MLF:	102430059(WDPCP)

MDT:	132213308(WDPCP)

MYUM:

139019941(WDPCP)

PKL:

118717424

EFUS:

103291532(WDPCP)

MNA:	107545960(WDPCP)

DRO:	112297886(WDPCP)

SHON:

118988429

AJM:	119035042(WDPCP)

PDIC:

114498694

PHAS:

123811567

MMF:

118630792

PPAM:

129081347(WDPCP)

HAI:	109378962(WDPCP)

RFQ:	117032939(WDPCP)

PALE:

102878551(WDPCP)

PGIG:

120621589

PVP:	105306704(WDPCP)

RAY:

107519877

MJV:

108402754

TOD:	119258992(WDPCP)

SARA:

101555112(WDPCP)

SFUM:

130035386(WDPCP)

SETR:

126024365(WDPCP)

LAV:	100659065(WDPCP)

TMU:

101359508

ETF:

101642381

DNM:	101423047(WDPCP)

MDO:	100033314(WDPCP)

GAS:

123233354

SHR:	100927222(WDPCP)

AFZ:

127548126

PCW:	110207708(WDPCP)

TVP:

118843765

PBRV:

138146862(WDPCP)

MLAO:

141502383(WDPCP)

OAA:

100082296

TACU:

119932442

GGA:	428553(WDPCP)

PCOC:

116232664(WDPCP)

MGP:	100540108(WDPCP)

CJO:	107310700(WDPCP)

TPAI:

128088495(WDPCP)

LMUT:

125689132

NMEL:

110395787(WDPCP)

APLA:

101795333

ACYG:

106045618(WDPCP)

CATA:

118251109(WDPCP)

AFUL:

116487102(WDPCP)

TGU:	100223341(WDPCP)

LSR:	110484872(WDPCP)

SCAN:

103821390(WDPCP)

PMOA:

120506817

OTC:

121335734

PRUF:

121358534

ATRC:

139588815(WDPCP)

GFR:	102043649(WDPCP)

FAB:	101807071(WDPCP)

OMA:	130251866(WDPCP)

PHI:	102110585(WDPCP)

PMAJ:

107202340(WDPCP)

CCAE:

111926541(WDPCP)

CCW:

104696613

CBRC:

103625028(WDPCP)

ACOE:

138107641(WDPCP)

ETL:	114064801(WDPCP)

ZAB:	102073991(WDPCP)

ZLE:	135445968(WDPCP)

ACHL:

103798558(WDPCP)

SVG:	106861665(WDPCP)

MMEA:

130582094(WDPCP)

HRT:	120751052(WDPCP)

SATI:

136359636(WDPCP)

CCIC:

134042292(WDPCP)

FPG:	101913648(WDPCP)

FCH:	102046765(WDPCP)

CCRI:

104162988(WDPCP)

NNT:	104409293(WDPCP)

SHAB:

115609251(WDPCP)

ACUN:

113477722(WDPCP)

TALA:

104368900

ACHC:

115344590

HALD:

104313272(WDPCP)

HLE:	104836436(WDPCP)

AGEN:

126038260

HHAR:

128140471(WDPCP)

GCL:

127014880

CSTI:

104553872(WDPCP)

LDI:	104342999(WDPCP)

MNB:	103772120(WDPCP)

DPUB:

104301442(WDPCP)

PPUS:

135176875(WDPCP)

AVIT:

104276781(WDPCP)

BRHI:

104494449(WDPCP)

EGZ:

104129380

NNI:	104014930(WDPCP)

PCRI:

104028083(WDPCP)

PCAO:

104041867(WDPCP)

PADL:

103919577(WDPCP)

AFOR:

103901679(WDPCP)

FGA:	104077489(WDPCP)

CBOR:

142081068(WDPCP)

GSTE:

104252668(WDPCP)

CBOY:

140649906(WDPCP)

MAME:

142407373(WDPCP)

CLV:	102084842(WDPCP)

CNIC:

135986955(WDPCP)

MUI:	104542254(WDPCP)

PGUU:

104472290(WDPCP)

PLET:

104617893(WDPCP)

EHS:	104510563(WDPCP)

CMAC:

104478262(WDPCP)

CUCA:

104055408(WDPCP)

TEO:	104378803(WDPCP)

BREG:

104637261(WDPCP)

OHA:	104333346(WDPCP)

ACAR:

104530354(WDPCP)

CPEA:

104385040(WDPCP)

CVF:	104295813(WDPCP)

RTD:	128906705(WDPCP)

CRID:

134512713(WDPCP)

LMIC:

141740449(WDPCP)

AAM:	106495263(WDPCP)

AROW:

112973155(WDPCP)

NPD:	112942925(WDPCP)

TGT:	104580495(WDPCP)

DNE:	112989329(WDPCP)

SCAM:

104151849(WDPCP)

ASN:	102375251(WDPCP)

AMJ:	102571178(WDPCP)

CPOO:

109319554(WDPCP)

GGN:	109296953(WDPCP)

PSS:	102451158(WDPCP)

CIZ:	142010862(WDPCP)

CMY:

CCAY:

DCC:

CPIC:

TST:	117874259(WDPCP)

CABI:

116815165(WDPCP)

MRV:

120401063

ACS:	100556755(wdpcp)

ASAO:

132780780(WDPCP)

PVT:	110084204(WDPCP)

SUND:

121924095

PBI:	103066750(WDPCP)

PMUR:

107284318(WDPCP)

CTIG:

120307839

TSR:	106547263(WDPCP)

PGUT:

117674461(WDPCP)

PCAE:

139326630(WDPCP)

APRI:

131197927(WDPCP)

PTEX:

113444239(WDPCP)

NSS:	113412683(WDPCP)

VKO:

123035809

PMUA:

114593505(WDPCP)

PRAF:

128409855(WDPCP)

ZVI:	118082655(WDPCP)

HCG:	128339860(WDPCP)

GJA:	107120024(WDPCP)

STOW:

125435538

EMC:	129344809(WDPCP)

XLA:	734894(wdpcp.L)

XTR:	100491624(wdpcp)

NPR:	108786416(WDPCP)

RTEM:

120937755

ACAT:

141140729(WDPCP)

BBUF:

120999260

BGAR:

122934711

DTC:	141057934(WDPCP)

PWL:	138295738(WDPCP)

MUO:	115465586(WDPCP)

GSH:	117357744(WDPCP)

DRE:	100333125(wdpcp)

SRX:	107715972 107744640

SANH:

107670804 107689811

SGH:	107553854 107583458 107583657

CCAR:

CAUA:

CGIB:

PTET:

LROH:

127180127(wdpcp)

GRF:	141296054(wdpcp)

OMC:	131522769(wdpcp)

PPRM:

120464004

RKG:	130097460(wdpcp)

MAMB:

125268773

CIDE:

127498141

CERY:

137007064(wdpcp)

MASI:

127410663

TROS:

130560575(wdpcp)

TDW:	130436933(wdpcp)

MANU:

129417664(wdpcp)

PDAB:

135737398(wdpcp)

IPU:

108269782

IFU:	128612457(wdpcp)

PHYP:

113544998(wdpcp)

SMEO:

124389974

TFD:

113640495

TVC:	132852345(wdpcp)

CGAR:

128536376(wdpcp)

NGRA:

132894114(wdpcp)

TRN:	134325221(wdpcp)

AMEX:

103029690

CMAO:

118823411

EEE:	113582160(wdpcp)

CHAR:

105893431

SPIL:

134064329(wdpcp)

ASAD:

121684948

TRU:	101072099(wdpcp)

TFS:	130533755(wdpcp)

TNG:	GSTEN00018706G001

LCO:	104931839(wdpcp)

NCC:	104942007(wdpcp)

TBEN:

117487212(wdpcp)

CGOB:

115020299(wdpcp)

PGEO:

117459704(wdpcp)

GACU:

117542341(wdpcp)

EMAC:

134858867(wdpcp)

ELY:	117248724(wdpcp)

EFO:

125903203

PLEP:

121954604

SLUC:

116061683

ECRA:

117960205(wdpcp)

ESP:	116705256(wdpcp)

PFLV:

114571686(wdpcp)

PPUG:

119214373(wdpcp)

AFB:	129091993(wdpcp)

CLUM:

117743760(wdpcp)

CANA:

137779458(wdpcp)

CVE:	137872221(wdpcp)

MSAM:

119917042

SCHU:

122884160

CUD:

121511283

SPUL:

138588566(wdpcp)

LMIX:

132975600(wdpcp)

HTC:	141795139(wdpcp)

ALAT:

119033544

ASTR:

137603345(wdpcp)

MZE:	101468494(wdpcp)

ONL:	100709843(wdpcp)

OAU:

116324855

OLA:	101163685(wdpcp)

OML:

112161615

CSAI:

133463452(wdpcp)

XMA:	102234710(wdpcp)

XCO:	114138453(wdpcp)

XHE:	116713522(wdpcp)

PRET:

103476493(wdpcp)

PFOR:

103152462(wdpcp)

PLAI:

106955487(wdpcp)

PMEI:

106913710(wdpcp)

GAF:

122842499

PPRL:

129360125(wdpcp)

CVG:	107094032(wdpcp)

CTUL:

119798097

GMU:

124859089

NFU:	107376055(wdpcp)

KMR:

108243008

ALIM:

106526765(wdpcp)

NWH:

119407813

AOCE:

111567597(wdpcp)

EJA:	138195127(wdpcp)

BFRE:

138634403(wdpcp)

MCEP:

125019337

CSEM:

103386936(wdpcp)

POV:	109630984(wdpcp)

SSEN:

122781922

SSOE:

131474246(wdpcp)

HHIP:

117775281(wdpcp)

HSP:

118118932

PPLT:

128453330(wdpcp)

SMAU:

118283267

LCF:

108873207

SDU:	111227439(wdpcp)

SLAL:

111661996(wdpcp)

XGL:

120796012

HCQ:	109526676(wdpcp)

SSCV:

125978067(wdpcp)

SBIA:

133510277(wdpcp)

PEE:	133410139(wdpcp)

PTAO:

133485675(wdpcp)

BPEC:

110156908

ENY:	140351373(wdpcp)

MALB:

109961147(wdpcp)

BSPL:

114842034(wdpcp)

SJO:	128372735(wdpcp)

SSCO:

133991464(wdpcp)

TTY:	137197366(wdpcp)

GMH:	115559998(wdpcp)

SASA:

106591852 106593770

OTW:

112241537

OMY:	110505954 118936402

OGO:

124020468

OKI:

116359710

OKE:	118382004(wdpcp)

OMM:	135511796 135513364

OCLA:

139413429

SALP:

112077592(wdpcp)

CCLU:

121572793

ELS:	105008318(wdpcp)

OEP:	134022159(wdpcp)

SFM:	108927008(wdpcp)

PKI:	111859364(wdpcp)

AANG:

118217890(wdpcp)

AROT:

135245273(wdpcp)

CCOG:

133118321(wdpcp)

LOC:	102697253(wdpcp)

PSPA:

121316132

ARUT:

117402976

PSEX:

120516726

LCM:	102361932(WDPCP)

CMK:

103177943

RTP:

109925087

CPLA:

122553140

HOC:	132819603(wdpcp)

SCAU:

119971744

LERI:

129699251(wdpcp)

HAKA:

140730560(wdpcp)

PMRN:

116939689(WDPCP)

LRJ:	133347342(WDPCP)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

SKO:

PFLL:

DME:	Dmel_CG17657(frtz)

DER:

6543272

DSE:

6617397

DSI:	Dsimw501_GD28664(Dsim_GD28664)

DYA:	Dyak_GE15489

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI16975

DAZ:

108610441

DNV:

108649641

DHE:

111599350

DVI:	6628670(frtz)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

MDE:	101887681 131801347

SCAC:

106085052

LCQ:

111680791

CVJ:	135951070(frtz)

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

ACOS:

AAG:	110681056 5573888

AALB:

109402785 109422605

ASUA:

134220855

CQU:	CpipJ_CPIJ013527

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:	108726760(frtz)

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

139106824(Frtz)

TLN:	139819287(Frtz)

HST:

DQU:

CFO:

FEX:

PMEC:

138940844(Frtz)

LHU:	105678307(frtz)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

AROA:

TCA:

TMOL:

138132780(frtz)

DPA:

109535812

ESIM:

136415116(frtz)

EFOR:

136345999(frtz)

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

108744661 108744822 112906594

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_208537A KGM_208537B

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137932742(frtz)

PRAP:

ZCE:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PGW:

LGLY:

CSTB:

CFUM:

141431980(frtz)

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

CLEC:

HHAL:

106687507(frtz)

NLU:	111045325 120351378

LDA:	142326640(frtz)

HVI:

124356995

MQU:	128986598 128987439

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138703059(frtz)

BROR:

134541058

IEL:

124157619

HAMR:

139700148(frtz)

FCD:

110847316

DPX:	DAPPUDRAFT_117600

DMK:

116929431

DPZ:

124310746

PVM:	113809433(frtz)

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123745300(frtz)

CQD:	128685446(frtz)

PTRU:

123519530

ESN:

127003579

MNZ:

135221733

MRJ:	136844462(frtz)

PORN:

139759564(frtz)

HAZT:

108677995

EAF:

111705634

LSM:	121120038(frtz)

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

GOE:

TUT:

DPTE:

DFR:

CSCU:

CVS:	136969301(frtz)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

HRO:	HELRODRAFT_179229

LGI:	LOTGIDRAFT_167175

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:	111127952 111127977

OED:

MYI:

PMAX:

AIRR:

YBA:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

LLON:

NVE:	116619872 5512302

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_55903

AQU:

100635233

SRE:	PTSG_05460

» show all

Reference

PMID:27158779

Authors

Toriyama M, Lee C, Taylor SP, Duran I, Cohn DH, Bruel AL, Tabler JM, Drew K, Kelly MR, Kim S, Park TJ, Braun DA, Pierquin G, Biver A, Wagner K, Malfroot A, Panigrahi I, Franco B, Al-Lami HA, Yeung Y, Choi YJ, Duffourd Y, Faivre L, Riviere JB, Chen J, Liu KJ, Marcotte EM, Hildebrandt F, Thauvin-Robinet C, Krakow D, Jackson PK, Wallingford JB

Title

The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery.

Journal

Nat Genet 48:648-56 (2016)
DOI:10.1038/ng.3558

Sequence

[mmu:216560]

LinkDB

DBGET integrated database retrieval system