KEGG MODULE: M00087

MODULE: M00087

Entry

M00087            Pathway   Module

Name

beta-Oxidation

Definition

(K00232,K00249,K00255,K06445,K09479) (((K01692,K07511,K13767) (K00022,K07516)),K01825,K01782,K07514,K07515,K10527) (K00632,K07508,K07509,K07513)

Diagram

Orthology

K00232

acyl-CoA oxidase [EC:1.3.3.6] [RN:R01279 R03990 R03857 R04754 R03777 R04751 R01175]

K00249

acyl-CoA dehydrogenase [EC:1.3.8.7] [RN:R01279 R03990 R03857 R04754 R03777 R04751 R01175]

K00255

long-chain-acyl-CoA dehydrogenase [EC:1.3.8.8] [RN:R01279 R03990 R03857 R04754 R03777 R04751 R01175]

K06445

acyl-CoA dehydrogenase [EC:1.3.99.-] [RN:R01279 R03990 R03857 R04754 R03777 R04751 R01175]

K09479

very long chain acyl-CoA dehydrogenase [EC:1.3.8.9] [RN:R01279 R03990 R03857 R04754 R03777 R04751 R01175]

K01692,K07511,K13767

enoyl-CoA hydratase [EC:4.2.1.17] [RN:R04738 R04740 R04170 R04744 R04746 R04749 R03026]

K00022,K07516

3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] [RN:R04737 R04739 R04741 R04743 R04745 R04748 R01975]

K01825,K01782

3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8] [RN:R04738 R04737 R04740 R04739 R04170 R04741 R04744 R04743 R04746 R04745 R04749 R04748 R03026 R01975]

K07514

enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8] [RN:R04738 R04737 R04740 R04739 R04170 R04741 R04744 R04743 R04746 R04745 R04749 R04748 R03026 R01975]

K07515

enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211] [RN:R04738 R04737 R04740 R04739 R04170 R04741 R04744 R04743 R04746 R04745 R04749 R04748 R03026 R01975]

K10527

enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35 1.1.1.211] [RN:R04738 R04737 R04740 R04739 R04170 R04741 R04744 R04743 R04746 R04745 R04749 R04748 R03026 R01975]

K00632,K07513,K07508,K07509

acetyl-CoA acyltransferase [EC:2.3.1.16] [RN:R03991 R03858 R04742 R03778 R04747 R01177 R00238]

Class

Pathway modules; Lipid metabolism; Fatty acid metabolism

Pathway

map00071

Fatty acid degradation

map01212

Fatty acid metabolism

map01100

Metabolic pathways

Reaction

R01279

C00154 -> C05272

R04738

C05272 -> C05258

R04737

C05258 -> C05259

R03991

C05259 -> C02593 + C00024

R03990

C02593 -> C05273

R04740

C05273 -> C05260

R04739

C05260 -> C05261

R03858

C05261 -> C01832 + C00024

R03857

C01832 -> C03221

R04170

C03221 -> C05262

R04741

C05262 -> C05263

R04742

C05263 -> C05274 + C00024

R04754

C05274 -> C05275

R04744

C05275 -> C05264

R04743

C05264 -> C05265

R03778

C05265 -> C01944 + C00024

R03777

C01944 -> C05276

R04746

C05276 -> C05266

R04745

C05266 -> C05267

R04747

C05267 -> C05270 + C00024

R04751

C05270 -> C05271

R04749

C05271 -> C05268

R04748

C05268 -> C05269

R01177

C05269 -> C00136 + C00024

R01175

C00136 -> C00877

R03026

C00877 -> C01144

R01975

C01144 -> C00332

R00238

C00332 -> C00024

Compound

C00154

Palmitoyl-CoA

C05272

trans-Hexadec-2-enoyl-CoA

C05258

(S)-3-Hydroxyhexadecanoyl-CoA

C05259

3-Oxopalmitoyl-CoA

C02593

Tetradecanoyl-CoA

C00024

Acetyl-CoA

C05273

trans-Tetradec-2-enoyl-CoA

C05260

(S)-3-Hydroxytetradecanoyl-CoA

C05261

3-Oxotetradecanoyl-CoA

C01832

Lauroyl-CoA

C03221

2-trans-Dodecenoyl-CoA

C05262

(S)-3-Hydroxydodecanoyl-CoA

C05263

3-Oxododecanoyl-CoA

C05274

Decanoyl-CoA

C05275

trans-Dec-2-enoyl-CoA

C05264

(S)-Hydroxydecanoyl-CoA

C05265

3-Oxodecanoyl-CoA

C01944

Octanoyl-CoA

C05276

trans-Oct-2-enoyl-CoA

C05266

(S)-3-Hydroxyoctanoyl-CoA

C05267

3-Oxooctanoyl-CoA

C05270

Hexanoyl-CoA

C05271

trans-Hex-2-enoyl-CoA

C05268

(S)-Hydroxyhexanoyl-CoA

C05269

3-Oxohexanoyl-CoA

C00136

Butanoyl-CoA

C00877

Crotonoyl-CoA

C01144

(S)-3-Hydroxybutanoyl-CoA

C00332

Acetoacetyl-CoA

RModule

RM018

Beta oxidation in acyl-CoA degradation

LinkDB

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