| Entry |
|
| Name |
Lovastatin biosynthesis, malonyl-CoA => lovastatin acid
|
| Definition |
K20981 K20982 K20985 K20980
K20984
K20983
|
| Diagram |
| M00893 | Lovastatin biosynthesis, malonyl-CoA => lovastatin acid |
|
| Class |
Pathway modules; Biosynthesis of other secondary metabolites; Biosynthesis of other fungal compounds
|
| Pathway |
| map00997 | Biosynthesis of various other secondary metabolites |
| map01110 | Biosynthesis of secondary metabolites |
|
| Orthology |
LOVG; dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase [EC: 3.1.2.31] [RN: R11187] LOVD; monacolin J acid methylbutanoate transferase [EC: 2.3.1.238] [RN: R11126] |
| Complete |
| 33178 | Aspergillus terreus |
|
| Reaction |
|
| Compound |
| C21108 | Dihydromonacolin L-[acyl-carrier protein] |
| C20852 | 3alpha-Hydroxy-3,5-dihydromonacolin L acid |
| C21129 | (S)-2-Methylbutanoyl-[acp] |
|
| Reference |
|
| Authors |
Xu W, Chooi YH, Choi JW, Li S, Vederas JC, Da Silva NA, Tang Y |
| Title |
LovG: the thioesterase required for dihydromonacolin L release and lovastatin nonaketide synthase turnover in lovastatin biosynthesis. |
| Journal |
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| LinkDB |
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