Entry |
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Name |
Lovastatin biosynthesis, malonyl-CoA => lovastatin acid
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Definition |
K20981 K20982 K20985 K20980
K20984
K20983
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Diagram |
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Orthology |
LOVG; dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase [EC: 3.1.2.31] [RN: R11187] LOVD; monacolin J acid methylbutanoate transferase [EC: 2.3.1.238] [RN: R11126] |
Class |
Pathway modules; Biosynthesis of other secondary metabolites; Biosynthesis of other fungal compounds
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Pathway |
map00997 | Biosynthesis of various other secondary metabolites |
map01110 | Biosynthesis of secondary metabolites |
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Reaction |
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Compound |
C21108 | Dihydromonacolin L-[acyl-carrier protein] |
C20852 | 3alpha-Hydroxy-3,5-dihydromonacolin L acid |
C21129 | (S)-2-Methylbutanoyl-[acp] |
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Reference |
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Authors |
Xu W, Chooi YH, Choi JW, Li S, Vederas JC, Da Silva NA, Tang Y |
Title |
LovG: the thioesterase required for dihydromonacolin L release and lovastatin nonaketide synthase turnover in lovastatin biosynthesis. |
Journal |
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LinkDB |
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