KEGG   Homo sapiens (human): 84557
Entry
84557             CDS       T01001                                 
Symbol
MAP1LC3A, ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3
Name
(RefSeq) microtubule associated protein 1 light chain 3 alpha
  KO
K10435  microtubule-associated protein 1 light chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04137  Mitophagy - animal
hsa04140  Autophagy - animal
hsa04216  Ferroptosis
hsa04371  Apelin signaling pathway
hsa04621  NOD-like receptor signaling pathway
hsa05014  Amyotrophic lateral sclerosis
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05131  Shigellosis
hsa05167  Kaposi sarcoma-associated herpesvirus infection
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06182  Shigella
nt06464  Amyotrophic lateral sclerosis
nt06466  Pathways of neurodegeneration
nt06532  Autophagy
nt06536  Mitophagy
  Element
N00156  Autophagy-vesicle nucleation/elongation/maturation, LC3-II formation
N01137  PINK-Parkin-mediated autophagosome formation
N01139  Mutation-inactivated p62 to PINK-Parkin-mediated autophagosome formation
N01140  TBK1-mediated autophagosome formation
N01141  Mutation-inactivated TBK1 to TBK1-mediated autophagosome formation
N01716  Autophagy-vesicle nucleation/elongation/maturation, sequestosome-1-like receptor
N01721  Autophagosome and lysosome fusion, tethering factor
N01722  Autophagosome and lysosome fusion, tethering factor, GRASP55
N01756  PINK-Parkin-independent ubiquitin-mediated mitophagy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    84557 (MAP1LC3A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    84557 (MAP1LC3A)
   04137 Mitophagy - animal
    84557 (MAP1LC3A)
  09143 Cell growth and death
   04216 Ferroptosis
    84557 (MAP1LC3A)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    84557 (MAP1LC3A)
 09160 Human Diseases
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    84557 (MAP1LC3A)
  09171 Infectious disease: bacterial
   05131 Shigellosis
    84557 (MAP1LC3A)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    84557 (MAP1LC3A)
   05022 Pathways of neurodegeneration - multiple diseases
    84557 (MAP1LC3A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    84557 (MAP1LC3A)
   03029 Mitochondrial biogenesis [BR:hsa03029]
    84557 (MAP1LC3A)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    84557 (MAP1LC3A)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    84557 (MAP1LC3A)
Mitochondrial biogenesis [BR:hsa03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Other mitophagy factors
    84557 (MAP1LC3A)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Microtubule-associated proteins (MAPs)
     84557 (MAP1LC3A)
SSDB
Motif
Pfam: ATG8 APG12 YneP
Other DBs
NCBI-GeneID: 84557
NCBI-ProteinID: NP_115903
OMIM: 601242
HGNC: 6838
Ensembl: ENSG00000101460
UniProt: Q9H492
Structure
LinkDB
Position
20:34546844..34560345
AA seq 121 aa
MPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM
SELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFG
F
NT seq 366 nt   +upstreamnt  +downstreamnt
atgccctcagaccggcctttcaagcagcggcggagcttcgccgaccgctgtaaggaggta
cagcagatccgcgaccagcaccccagcaaaatcccggtgatcatcgagcgctacaagggt
gagaagcagctgcccgtcctggacaagaccaagtttttggtcccggaccatgtcaacatg
agcgagttggtcaagatcatccggcgccgcctgcagctgaaccccacgcaggccttcttc
ctgctggtgaaccagcacagcatggtgagtgtgtccacgcccatcgcggacatctacgag
caggagaaagacgaggacggcttcctctatatggtctacgcctcccaggaaaccttcggc
ttctga

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