KEGG   REACTION: R02235
Entry
R02235                      Reaction                               

Name
dihydrofolate:NAD+ oxidoreductase
Definition
Dihydrofolate + NAD+ <=> Folate + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00158  C00415_C00504
Enzyme
Pathway
rn00670  One carbon pool by folate
rn00790  Folate biosynthesis
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Orthology
K00287  dihydrofolate reductase [EC:1.5.1.3]
K13998  dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
K18589  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K18590  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K18591  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K19643  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K19644  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
LinkDB

KEGG   REACTION: R02236
Entry
R02236                      Reaction                               

Name
dihydrofolate:NADP+ oxidoreductase
Definition
Dihydrofolate + NADP+ <=> Folate + NADPH + H+
Equation
Reaction class
RC00001  C00005_C00006
RC00158  C00415_C00504
Enzyme
Pathway
rn00670  One carbon pool by folate
rn00790  Folate biosynthesis
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Orthology
K00287  dihydrofolate reductase [EC:1.5.1.3]
K13998  dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
K18589  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K18590  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K18591  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K19643  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K19644  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Other DBs
RHEA: 31106
LinkDB

KEGG   RCLASS: RC00158
Entry
RC00158                     RClass                                 

Definition
C1x-C8x:*-*:C2y+N1x-C8y+N5x
N1x-N5x:*-*:C1x+C8y-C8x+C8y
Reactant pair
Related class
Reaction
Enzyme
1.5.1.3         1.5.1.33
Pathway
rn00670  One carbon pool by folate
rn00790  Folate biosynthesis
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Orthology
K00287  dihydrofolate reductase [EC:1.5.1.3]
K03793  pteridine reductase [EC:1.5.1.33]
K13998  dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
K18589  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K18590  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K18591  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K19643  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K19644  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]

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