REACTION: R10208
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Entry
R10208 Reaction
Name
(3R)-3-hydroxyacyl-[acyl-carrier protein] hydro-lyase (trans-2-enoyl-[acyl-carrier protein]-forming)
Definition
(3R)-3-Hydroxyacyl-[acyl-carrier protein] <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + H2O
Equation
C01271
<=>
C00693
+
C00001
Comment
general reaction
Reaction class
RC00770
C00693_C01271
Enzyme
4.2.1.59
4.2.1.-
Pathway
rn00061
Fatty acid biosynthesis
rn01100
Metabolic pathways
Orthology
K01716
3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:
4.2.1.59
5.3.3.14
]
K02372
3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:
4.2.1.59
]
K16363
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:
3.5.1.108
4.2.1.59
]
K22540
3-hydroxyacyl-thioester dehydratase, animal type [EC:4.2.1.-]
K22541
3-hydroxyacyl-thioester dehydratase, fungi type [EC:4.2.1.-]
Reference
1 [PMID:
27553474
]
Authors
Kastaniotis AJ, Autio KJ, Keratar JM, Monteuuis G, Makela AM, Nair RR, Pietikainen LP, Shvetsova A, Chen Z, Hiltunen JK
Title
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
Journal
Biochim Biophys Acta Mol Cell Biol Lipids 1862:39-48 (2017)
DOI:
10.1016/j.bbalip.2016.08.011
Other DBs
RHEA:
13100
LinkDB
All DBs
RCLASS: RC00770
Help
Entry
RC00770 RClass
Definition
C1b-C2b:*-*:C1c+C5a-C2b+C5a
C1c-C2b:O1a-*:C1b+R-C2b+R
Reactant pair
C00640_C00658
C00658_C01086
C00693_C01271
C01086_C01122
C20878_C20879
Related class
DB search
Reaction
R02685
R03224
R09698
R10208
R10827
Enzyme
4.2.1.17
4.2.1.59
4.2.1.74
4.2.1.119
4.2.1.134
4.2.1.-
Pathway
rn00061
Fatty acid biosynthesis
rn00062
Fatty acid elongation
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
Orthology
K01716
3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:
4.2.1.59
5.3.3.14
]
K02372
3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:
4.2.1.59
]
K07511
enoyl-CoA hydratase [EC:
4.2.1.17
]
K07515
enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:
4.2.1.17
1.1.1.211
]
K10703
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:
4.2.1.134
]
K12405
(3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.-
4.2.1.107
4.2.1.119
]
K16363
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:
3.5.1.108
4.2.1.59
]
K19658
peroxisomal enoyl-CoA hydratase 2 [EC:
4.2.1.119
]
K19659
enoyl-CoA hydratase [EC:
4.2.1.119
]
K22540
3-hydroxyacyl-thioester dehydratase, animal type [EC:4.2.1.-]
K22541
3-hydroxyacyl-thioester dehydratase, fungi type [EC:4.2.1.-]
DBGET
integrated database retrieval system
