KEGG   REACTION: R10826
Entry
R10826                      Reaction                               
Name
very-long-chain-(3R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase
Definition
Very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ <=> Very-long-chain 3-oxoacyl-CoA + NADPH + H+
Equation
C20878 + C00006 <=> C20877 + C00005 + C00080
Comment
Elongation of C16/C18 acyl-CoAs to very-long-chain acyl CoAs.
Reaction class
RC00001  C00005_C00006
RC00029  C20877_C20878
Enzyme
1.1.1.330
Pathway
rn00062  Fatty acid elongation
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.330
     R10826  Very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ <=> Very-long-chain 3-oxoacyl-CoA + NADPH + H+
Orthology
K10251  17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
Other DBs
RHEA: 48683
LinkDB

KEGG   RCLASS: RC00103
Entry
RC00103                     RClass                                 
Definition
C1c-C5a:*-*:C1b+O1a+R-C1b+O5a+R
Reactant pair
C00264_C00640    C00264_C01086    C00685_C01271
C01506_C03667
Related class
Reaction
R01778 R01779 R02766 R02767 R03584 R03585
Enzyme
1.1.1.35        1.1.1.36        1.1.1.100       1.1.1.185       
1.1.1.211       1.1.1.212       1.1.1.-
Pathway
rn00061  Fatty acid biosynthesis
rn00062  Fatty acid elongation
rn01100  Metabolic pathways
Orthology
K00022  3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
K00023  acetoacetyl-CoA reductase [EC:1.1.1.36]
K00059  3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
K07515  enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
K11539  carbonyl reductase 4 / 3-oxoacyl-[acyl-carrier protein] reductase beta subunit [EC:1.1.1.-]

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