KEGG PATHWAY: amq00564

PATHWAY: amq00564

Entry

amq00564                    Pathway

Name

Glycerophospholipid metabolism - Amycolatopsis methanolica

Class

Metabolism; Lipid metabolism

Pathway map

amq00564

Glycerophospholipid metabolism

Module

amq_M00091

Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:amq00564]

amq_M00093

Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:amq00564]

Other DBs

GO:

0006650

Organism

Amycolatopsis methanolica [GN:amq]

Gene

AMETH_1533

gpsA; glycerol-3-phosphate dehydrogenase [KO:K00057] [EC:1.1.1.94]

AMETH_0863

glpA; glycerol-3-phosphate dehydrogenase [KO:K00111] [EC:1.1.5.3]

AMETH_3739

glpA; glycerol-3-phosphate dehydrogenase [KO:K00111] [EC:1.1.5.3]

AMETH_4658

glpA; Glycerol-3-phosphate dehydrogenase [KO:K00111] [EC:1.1.5.3]

AMETH_2712

plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [KO:K00655] [EC:2.3.1.51]

AMETH_0944

plsC; 1-acylglycerol-3-phosphate O-acyltransferase [KO:K00655] [EC:2.3.1.51]

AMETH_4900

plsC; phospholipid/glycerol acyltransferase [KO:K00655] [EC:2.3.1.51]

AMETH_3526

sphingosine kinase/diacylglycerol kinase [KO:K07029] [EC:2.7.1.107]

AMETH_4401

plcC; phospholipase C [KO:K01114] [EC:3.1.4.3]

AMETH_3489

glpQ; glycerophosphoryl diester phosphodiesterase [KO:K01126] [EC:3.1.4.46]

AMETH_6853

glpQ; glycerophosphoryl diester phosphodiesterase [KO:K01126] [EC:3.1.4.46]

AMETH_5955

methyltransferase [KO:K00570] [EC:2.1.1.17 2.1.1.71]

AMETH_1644

cdsA; phosphatidate cytidylyltransferase [KO:K00981] [EC:2.7.7.41]

AMETH_6429

pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase [KO:K17103] [EC:2.7.8.8]

AMETH_6428

psd; phosphatidylserine decarboxylase [KO:K01613] [EC:4.1.1.65]

AMETH_2496

pgsA; CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase [KO:K00995] [EC:2.7.8.5]

AMETH_2998

pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [KO:K08744] [EC:2.7.8.41]

Compound

C00040

Acyl-CoA

C00065

L-Serine

C00084

Acetaldehyde

C00093

sn-Glycerol 3-phosphate

C00111

Glycerone phosphate

C00114

Choline

C00157

Phosphatidylcholine

C00189

Ethanolamine

C00269

CDP-diacylglycerol

C00307

CDP-choline

C00344

Phosphatidylglycerol

C00346

Ethanolamine phosphate

C00350

Phosphatidylethanolamine

C00416

Phosphatidate

C00513

CDP-glycerol

C00570

CDP-ethanolamine

C00588

Choline phosphate

C00623

sn-Glycerol 1-phosphate

C00641

1,2-Diacyl-sn-glycerol

C00670

sn-Glycero-3-phosphocholine

C00681

1-Acyl-sn-glycerol 3-phosphate

C01194

1-Phosphatidyl-D-myo-inositol

C01210

N-Methylethanolamine phosphate

C01233

sn-Glycero-3-phosphoethanolamine

C01241

Phosphatidyl-N-methylethanolamine

C01996

Acetylcholine

C02737

Phosphatidylserine

C03372

Acylglycerone phosphate

C03819

1-Acylglycerophosphoinositol

C03872

L-Serine-phosphoethanolamine

C03892

Phosphatidylglycerophosphate

C03974

2-Acyl-sn-glycerol 3-phosphate

C04230

1-Acyl-sn-glycero-3-phosphocholine

C04233

2-Acyl-sn-glycero-3-phosphocholine

C04308

Phosphatidyl-N-dimethylethanolamine

C04438

1-Acyl-sn-glycero-3-phosphoethanolamine

C04590

3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate

C04638

2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate

C05973

2-Acyl-sn-glycero-3-phosphoethanolamine

C05974

2-Acyl-sn-glycero-3-phosphoserine

C05976

Aminoacyl-phosphatidylglycerol

C05980

Cardiolipin

C06771

Triethanolamine

C06772

Diethanolamine

C13482

Phosphodimethylethanolamine

C18059

CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol

C18125

1-Acyl-sn-glycero-3-phosphoserine

C18126

1-Acyl-sn-glycero-3-phosphoglycerol

C18129

Monolysocardiolipin

C18168

Diacylglycerylhomoserine

C18169

Diacylglyceryl-N,N,N-trimethylhomoserine

C20466

2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine

C20518

2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate

C22340

Heptaprenylglyceryl phosphate

C22341

Heptaprenylglycerol

C22342

Diacetylheptaprenylglycerol

Reference

PMID:1512203

Authors

Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.

Title

The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.

Journal

J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992

Reference

PMID:10092508

Authors

Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.

Title

Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.

Journal

Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411

Reference

PMID:10542045

Authors

Athenstaedt K, Daum G.

Title

Phosphatidic acid, a key intermediate in lipid metabolism.

Journal

Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x

Reference

PMID:12431977

Authors

Shields DJ, Lehner R, Agellon LB, Vance DE.

Title

Membrane topography of human phosphatidylethanolamine N-methyltransferase.

Journal

J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200

Reference

PMID:14663079

Authors

Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.

Title

Pathways for phosphatidylcholine biosynthesis in bacteria.

Journal

Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0

Reference

PMID:15522832

Authors

Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.

Title

Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.

Journal

Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007

Reference

PMID:1649829

Authors

Hsu L, Jackowski S, Rock CO

Title

Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.

Journal

J Biol Chem 266:13783-8 (1991)

Reference

PMID:10938271

Authors

Stone SJ, Vance JE.

Title

Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.

Journal

J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200

Related
pathway

amq00010