KEGG   PATHWAY: bit00620
Entry
bit00620                    Pathway                                
Name
Pyruvate metabolism - Bacillus spizizenii
Class
Metabolism; Carbohydrate metabolism
Pathway map
bit00620  Pyruvate metabolism
bit00620

Module
bit_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:bit00620]
bit_M00579  Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:bit00620]
Other DBs
GO: 0006090
Organism
Bacillus spizizenii [GN:bit]
Gene
BIS30_04160  acyl--CoA ligase [KO:K01895] [EC:6.2.1.1]
BIS30_04225  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
BIS30_18105  pyruvate dehydrogenase [KO:K00161] [EC:1.2.4.1]
BIS30_18110  2-oxoisovalerate dehydrogenase [KO:K00162] [EC:1.2.4.1]
BIS30_18115  branched-chain alpha-keto acid dehydrogenase subunit E2 [KO:K00627] [EC:2.3.1.12]
BIS30_01745  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
BIS30_18120  dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
BIS30_14655  acoL; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
BIS30_02825  dehydrogenase [KO:K00121] [EC:1.1.1.284 1.1.1.1]
BIS30_02870  alcohol dehydrogenase [KO:K13979] [EC:1.1.1.2]
BIS30_04115  acetate kinase [KO:K00925] [EC:2.7.2.1]
BIS30_08545  eutD; phosphotransacetylase [KO:K00625] [EC:2.3.1.8]
BIS30_04025  pyruvate kinase [KO:K00873] [EC:2.7.1.40]
BIS30_04035  acetyl-CoA carboxylase subunit alpha [KO:K01962] [EC:6.4.1.2 2.1.3.15]
BIS30_01905  acetyl-CoA carboxylase [KO:K02160]
BIS30_20000  acetyl-CoA carboxylase [KO:K02160]
BIS30_20005  biotin carboxylase [KO:K01961] [EC:6.4.1.2 6.3.4.14]
BIS30_04040  acetyl-CoA carboxyl transferase [KO:K01963] [EC:6.4.1.2 2.1.3.15]
BIS30_14425  acylphosphatase [KO:K01512] [EC:3.6.1.7]
BIS30_00185  betaine-aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
BIS30_08700  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
BIS30_09200  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
BIS30_09805  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
BIS30_12760  thiamine pyrophosphate-binding protein [KO:K00158] [EC:1.2.3.3]
BIS30_12070  lactate dehydrogenase [KO:K00016] [EC:1.1.1.27]
BIS30_06325  glyoxal reductase [KO:K23257] [EC:1.1.1.283 1.1.1.-]
BIS30_03955  glyoxal reductase [KO:K23257] [EC:1.1.1.283 1.1.1.-]
BIS30_10250  hypothetical protein [KO:K01759] [EC:4.4.1.5]
BIS30_08950  hypothetical protein [KO:K01759] [EC:4.4.1.5]
BIS30_03765  glyoxalase [KO:K01759] [EC:4.4.1.5]
BIS30_14205  hypothetical protein [KO:K01759] [EC:4.4.1.5]
BIS30_02135  hypothetical protein [KO:K01069] [EC:3.1.2.6]
BIS30_06960  bifunctional glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BIS30_01435  NAD-dependent malic enzyme 1 [KO:K00027] [EC:1.1.1.38]
BIS30_04045  malate dehydrogenase [KO:K00027] [EC:1.1.1.38]
BIS30_04320  malate dehydrogenase [KO:K00027] [EC:1.1.1.38]
BIS30_08245  malate dehydrogenase [KO:K00027] [EC:1.1.1.38]
BIS30_18255  pyruvate carboxylase [KO:K01958] [EC:6.4.1.1]
BIS30_03995  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BIS30_06120  fumarate hydratase [KO:K01679] [EC:4.2.1.2]
BIS30_02645  fumarate hydratase [KO:K01679] [EC:4.2.1.2]
BIS30_04660  phosphoenolpyruvate carboxykinase [KO:K01610] [EC:4.1.1.49]
BIS30_01800  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
BIS30_15880  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00033  Acetate
C00036  Oxaloacetate
C00042  Succinate
C00058  Formate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00083  Malonyl-CoA
C00084  Acetaldehyde
C00122  Fumarate
C00149  (S)-Malate
C00186  (S)-Lactate
C00227  Acetyl phosphate
C00256  (R)-Lactate
C00332  Acetoacetyl-CoA
C00424  (S)-Lactaldehyde
C00469  Ethanol
C00546  Methylglyoxal
C00937  (R)-Lactaldehyde
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C02488  (R)-2-Ethylmalate
C02504  alpha-Isopropylmalate
C03248  Acetylenedicarboxylate
C03451  (R)-S-Lactoylglutathione
C03981  2-Hydroxyethylenedicarboxylate
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C05993  Acetyl adenylate
C05994  2-Propylmalate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Related
pathway
bit00010  Glycolysis / Gluconeogenesis
bit00020  Citrate cycle (TCA cycle)
bit00061  Fatty acid biosynthesis
bit00250  Alanine, aspartate and glutamate metabolism
bit00260  Glycine, serine and threonine metabolism
bit00290  Valine, leucine and isoleucine biosynthesis
bit00300  Lysine biosynthesis
bit00630  Glyoxylate and dicarboxylate metabolism
bit00640  Propanoate metabolism
bit00650  Butanoate metabolism
bit00760  Nicotinate and nicotinamide metabolism
KO pathway
ko00620   
LinkDB

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