KEGG   PATHWAY: cel04142
Entry
cel04142                    Pathway                                
Name
Lysosome biogenesis - Caenorhabditis elegans (nematode)
Description
Lysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than 40 hydrolases in an acidic environment (pH of about 5). After synthesis in the ER, lysosomal enzymes are decorated with mannose-6-phosphate residues, which are recognized by mannose-6-phosphate receptors in the trans-Golgi network. They are packaged into clathrin-coated vesicles and are transported to late endosomes. Substances for digestion are acquired by the lysosomes via a series of processes including endocytosis, phagocytosis, and autophagy.
Class
Cellular Processes; Transport and catabolism
Pathway map
cel04142  Lysosome biogenesis
cel04142

Other DBs
GO: 0005764
Organism
Caenorhabditis elegans (nematode) [GN:cel]
Gene
CELE_B0252.2  asm-1; Sphingomyelin phosphodiesterase 1 [KO:K12350] [EC:3.1.4.12]
CELE_B0261.2  let-363; Target of rapamycin homolog [KO:K07203] [EC:2.7.11.1]
CELE_B0303.9  vps-33.1; Vacuolar protein sorting-associated protein 33A [KO:K20182]
CELE_B0513.9  vamp-8; V-SNARE coiled-coil homology domain-containing protein [KO:K08512]
CELE_C01G8.2  cln-3.2; Battenin [KO:K12389]
CELE_C02B10.2  snpn-1; SNAPIN protein homolog [KO:K20002]
CELE_C03B1.12  lmp-1; LAMP family protein lmp-1 [KO:K06528]
CELE_C05C10.1  pho-10; Putative acid phosphatase 10 [KO:K14410] [EC:3.1.3.2]
CELE_C05C10.4  pho-11; Putative acid phosphatase 11 [KO:K14410] [EC:3.1.3.2]
CELE_C05D11.2  vps-16; Vacuolar protein sorting-associated protein 16 homolog [KO:K20180]
CELE_C06H2.6  lmtr-3; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 [KO:K04370]
CELE_C07B5.5  nuc-1; Deoxyribonuclease-2 [KO:K01158] [EC:3.1.22.1]
CELE_C07H6.6  clk-2; Telomere length regulation protein clk-2 [KO:K11137]
CELE_C10C5.6  daf-15; Raptor N-terminal CASPase-like domain-containing protein [KO:K07204]
CELE_C10H11.8  mlst-8; Target of rapamycin complex subunit lst8 [KO:K08266]
CELE_C13F10.2  kxd-1; KxDL domain-containing protein [KO:K20818]
CELE_C17H12.14  vha-8; V-type proton ATPase subunit E [KO:K02150]
CELE_C25B8.3  cpr-6; Cathepsin B-like cysteine proteinase 6 [KO:K01363] [EC:3.4.22.1]
CELE_C26H9A.1  vha-7; V-type proton ATPase 116 kDa subunit a 4 [KO:K02154]
CELE_C27A2.12  C27A2.12; Histidine acid phosphatase [KO:K14410] [EC:3.1.3.2]
CELE_C27A2.4  pho-12; Lysosomal acid phosphatase [KO:K14410] [EC:3.1.3.2]
CELE_C28C12.7  spp-10; Saposin B-type domain-containing protein [KO:K12382]
CELE_C29E4.10  C29E4.10; Putative galactocerebrosidase [KO:K01202] [EC:3.2.1.46]
CELE_C30F8.2  vha-16; V-type proton ATPase subunit [KO:K02146]
CELE_C33C12.3  gba-1; Putative glucosylceramidase 1 [KO:K01201] [EC:3.2.1.45]
CELE_C33C12.8  gba-2; Putative glucosylceramidase 2 [KO:K01201] [EC:3.2.1.45]
CELE_C33G3.4  C33G3.4; putative beta-mannosidase [KO:K01192] [EC:3.2.1.25]
CELE_C34B7.2  figo-1; SAC domain-containing protein [KO:K22913] [EC:3.1.3.-]
CELE_C41C4.7  ctns-1; Cystinosin homolog [KO:K12386]
CELE_C47A4.2  ent-4; Equilibrative nucleoside transporter 1 [KO:K15014]
CELE_C52E4.1  cpr-1; Gut-specific cysteine proteinase [KO:K01363] [EC:3.4.22.1]
CELE_EGAP2.3  pho-1; Intestinal acid phosphatase [KO:K14410] [EC:3.1.3.2]
CELE_F02E8.3  aps-2; AP complex subunit sigma [KO:K11827]
CELE_F02E8.6  ncr-1; NPC intracellular cholesterol transporter 1 homolog 1 [KO:K12385]
CELE_F02E9.7  F02E9.7; Tartrate-resistant acid phosphatase type 5 [KO:K14379] [EC:3.1.3.2]
CELE_F07B10.1  cln-3.1; Battenin [KO:K12389]
CELE_F07H5.9  pho-13; intestinal acid PHOsphatase [KO:K14410] [EC:3.1.3.2]
CELE_F09G8.2  crn-7; Cell-death-related nuclease 7 [KO:K01158] [EC:3.1.22.1]
CELE_F11E6.1  gba-3; Putative glucosylceramidase 3 [KO:K01201] [EC:3.2.1.45]
CELE_F13D12.6  ctsa-1.2; Serine carboxypeptidase ctsa-1.2 [KO:K13289] [EC:3.4.16.5]
CELE_F13H10.3  F13H10.3; Sodium-coupled neutral amino acid transporter 9 homolog [KO:K14995]
CELE_F14D7.6  F14D7.6; MFS domain-containing protein [KO:K12307]
CELE_F16H11.3  ent-5; Equilibrative nucleoside transporter 1 [KO:K15014]
CELE_F20B6.2  vha-12; V-type proton ATPase subunit B 1 [KO:K02147]
CELE_F26C11.1  F26C11.1; Putative acid phosphatase F26C11.1 [KO:K14410] [EC:3.1.3.2]
CELE_F27E5.1  asah-2; putative acid ceramidase [KO:K12348] [EC:3.5.1.23]
CELE_F29G9.3  aps-1; AP complex subunit sigma [KO:K12394]
CELE_F32A6.3  vps-41; Vacuolar protein sorting-associated protein 41 homolog [KO:K20184]
CELE_F32B5.8  cpz-1; Cathepsin Z-1 [KO:K08568] [EC:3.4.18.1]
CELE_F32H5.1  F32H5.1; Peptidase C1A papain C-terminal domain-containing protein [KO:K01363] [EC:3.4.22.1]
CELE_F35H10.4  vha-5; V-type proton ATPase 116 kDa subunit a 2 [KO:K02154]
CELE_F36D3.9  cpr-2; Peptidase C1A papain C-terminal domain-containing protein [KO:K01363] [EC:3.4.22.1]
CELE_F36G3.3  F36G3.3; LITAF domain-containing protein [KO:K19363]
CELE_F36H2.2  ent-6; Equilibrative nucleoside transporter 3 [KO:K15014]
CELE_F41C3.5  ctsa-1.1; Serine carboxypeptidase ctsa-1.1 [KO:K13289] [EC:3.4.16.5]
CELE_F41E6.6  tag-196; Cathepsin F [KO:K01373] [EC:3.4.22.41]
CELE_F42A8.3  cup-15; Coelomocyte uptake defective protein 15 [KO:K23863]
CELE_F43E2.4  haf-2; ABC-type antigen peptide transporter [KO:K05656]
CELE_F44C4.3  cpr-4; Cathepsin B-like cysteine proteinase 4 [KO:K01363] [EC:3.4.22.1]
CELE_F44C4.5  ppt-1; Palmitoyl-protein thioesterase 1 [KO:K01074] [EC:3.1.2.22]
CELE_F44D12.9  ent-7; Equilibrative Nucleoside Transporter (ENT) Family [KO:K15014]
CELE_F46F11.5  vha-10; putative V-type proton ATPase subunit G [KO:K02152]
CELE_F49C12.13  vha-17; V-type proton ATPase subunit e [KO:K02153]
CELE_F52E1.10  vha-18; putative V-type proton ATPase subunit H 1 [KO:K02144]
CELE_F52E1.13  lmd-3; Oxidation resistance protein 1 [KO:K25442]
CELE_F53H8.1  apm-3; MHD domain-containing protein [KO:K12398]
CELE_F54E4.1  rbc-1; RAVE complex protein Rav1 C-terminal domain-containing protein [KO:K24155]
CELE_F54F3.3  lipl-1; Lipase lipl-1 [KO:K01052] [EC:3.1.1.13]
CELE_F55A12.7  apm-1; MHD domain-containing protein [KO:K12393]
CELE_F55D10.1  aman-1; Alpha-mannosidase [KO:K12311] [EC:3.2.1.24]
CELE_F55H2.2  vha-14; V-type proton ATPase subunit D [KO:K02149]
CELE_F57F5.1  cpr-9; Peptidase C1A papain C-terminal domain-containing protein [KO:K01363] [EC:3.4.22.1]
CELE_F59B2.2  skat-1; putative amino acid transporter skat-1 [KO:K14209]
CELE_F59E12.11  sam-4; BLOC-1-related complex subunit 5 [KO:K20819]
CELE_F59G1.3  vps-35; Vacuolar protein sorting-associated protein 35 [KO:K18468]
CELE_H14A12.3  H14A12.3; Protein rogdi homolog [KO:K24628]
CELE_H22K11.1  asp-3; Aspartic protease 3 [KO:K01379] [EC:3.4.23.5]
CELE_H32K16.1  slc-36.4; Amino acid transporter transmembrane domain-containing protein [KO:K14209]
CELE_K02D10.5  snap-29; Soluble NSF attachment protein 29 [KO:K08509]
CELE_K04H4.6  crn-6; Cell death-related nuclease 6 [KO:K01158] [EC:3.1.22.1]
CELE_K08E7.1  eak-7; MTOR-associated protein MEAK7 [KO:K27947]
CELE_K09A9.3  ent-2; Equilibrative nucleoside transporter 3 [KO:K15014]
CELE_K09E4.4  K09E4.4; Alpha-N-acetylglucosaminidase [KO:K01205] [EC:3.2.1.50]
CELE_K11B4.2  blos-9; BLOC-1-related complex subunit 8 homolog [KO:K20822]
CELE_K11D2.2  asah-1; Acid ceramidase subunit beta [KO:K12348] [EC:3.5.1.23]
CELE_K11D2.3  unc-101; AP-1 complex subunit mu-1-I [KO:K12393]
CELE_K11G12.3  smf-2; NRAMP-like transporter smf-2 [KO:K21398]
CELE_K11G12.4  smf-1; NRAMP-like transporter smf-1 [KO:K21398]
CELE_M04G12.2  cpz-2; cathepsin X [KO:K08568] [EC:3.4.18.1]
CELE_M05B5.4  plag-15; PhosphoLipase A2 Group [KO:K06129] [EC:3.1.1.5]
CELE_R04B3.2  R04B3.2; Glycosylasparaginase beta chain [KO:K01444] [EC:3.5.1.26]
CELE_R06F6.2  vps-11; Vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
CELE_R07B7.1  clh-6; Chloride channel protein [KO:K05016]
CELE_R07B7.11  gana-1; Alpha-galactosidase [KO:K01204] [EC:3.2.1.49]
CELE_R07E4.4  mig-23; Nucleoside-diphosphatase mig-23 [KO:K12305] [EC:3.6.1.6]
CELE_R10E11.2  vha-2; V-type proton ATPase 16 kDa proteolipid subunit c 3 [KO:K02155]
CELE_R10E11.8  vha-1; V-type proton ATPase 16 kDa proteolipid subunit c 1 [KO:K02155]
CELE_R10H10.7  R10H10.7; Non-specific serine/threonine protein kinase [KO:K20403]
CELE_R11A5.1  apb-3; AP-3 complex subunit beta [KO:K12397]
CELE_R12H7.2  asp-4; Aspartic protease 4 [KO:K01379] [EC:3.4.23.5]
CELE_R13A5.1  cup-5; Polycystin cation channel PKD1/PKD2 domain-containing protein [KO:K04994]
CELE_R148.2  lmtr-5; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 [KO:K16344]
CELE_R148.6  heh-1; Putative protein heh-1 [KO:K13443]
CELE_R160.1  dpy-23; AP-2 complex subunit mu [KO:K11826]
CELE_T01H3.1  vha-4; V-type proton ATPase 21 kDa proteolipid subunit c'' [KO:K03661]
CELE_T03E6.7  cpl-1; Cathepsin L-like [KO:K01365] [EC:3.4.22.15]
CELE_T08G11.1  vps-13A; Vacuolar protein sorting-associated protein 13 [KO:K19525]
CELE_T08G5.5  vps-39; Vacuolar protein sorting-associated protein 39 homolog [KO:K20183]
CELE_T09B9.2  slc-17.9; Major facilitator superfamily (MFS) profile domain-containing protein [KO:K12301]
CELE_T10H4.12  cpr-3; Cathepsin B-like cysteine proteinase 3 [KO:K01363] [EC:3.4.22.1]
CELE_T13B5.3  pho-14; Histidine acid phosphatase [KO:K14410] [EC:3.1.3.2]
CELE_T14F9.1  vha-15; putative V-type proton ATPase subunit H 2 [KO:K02144]
CELE_T14F9.3  hex-1; Beta-hexosaminidase A [KO:K12373] [EC:3.2.1.52]
CELE_T16D1.2  pho-4; intestinal acid PHOsphatase [KO:K14410] [EC:3.1.3.2]
CELE_T19B10.3  bgal-1; Beta-galactosidase [KO:K12309] [EC:3.2.1.23]
CELE_T20B5.1  apa-2; AP-2 complex subunit alpha [KO:K11824]
CELE_T20D3.7  vps-26; Vacuolar protein sorting-associated protein 26 [KO:K18466]
CELE_T20G5.1  chc-1; putative clathrin heavy chain 1 [KO:K04646]
CELE_T20G5.10  blos-1; Biogenesis of lysosome-related organelles complex 1 subunit 1 [KO:K20185]
CELE_T22C8.2  chhy-1; Chondroitin hydrolase [KO:K01197] [EC:3.2.1.35]
CELE_T23D8.2  tsp-7; Tetraspanin [KO:K06497]
CELE_T24F1.1  raga-1; GTP-binding protein [KO:K16185]
CELE_T27A1.5  slc-36.2; Amino acid transporter transmembrane domain-containing protein [KO:K14209]
CELE_T28H10.3  lgmn-1; legumain [KO:K01369] [EC:3.4.22.34]
CELE_VF39H2L.1  syx-17; t-SNARE coiled-coil homology domain-containing protein [KO:K08491]
CELE_VW02B12L.1  vha-6; V-type proton ATPase 116 kDa subunit a 3 [KO:K02154]
CELE_W03C9.3  rab-7; Ras-related protein Rab-7a [KO:K07897]
CELE_W03G1.7  asm-3; Putative sphingomyelin phosphodiesterase asm-3 [KO:K12350] [EC:3.1.4.12]
CELE_W03G11.3  W03G11.3; Putative alpha-L-fucosidase [KO:K01206] [EC:3.2.1.51]
CELE_W04C9.1  haf-4; ABC-type antigen peptide transporter [KO:K05656]
CELE_W04G3.4  apt-9; ADP-ribosylation factor-binding protein GGA1 [KO:K12404]
CELE_W06B4.3  vps-18; Vacuolar protein sorting-associated protein 18 homolog [KO:K20181]
CELE_W07B8.1  cpr-8; Peptidase C1A papain C-terminal domain-containing protein [KO:K01363] [EC:3.4.22.1]
CELE_W07B8.4  W07B8.4; Peptidase C1A papain C-terminal domain-containing protein [KO:K01363] [EC:3.4.22.1]
CELE_W07B8.5  cpr-5; Cathepsin B-like cysteine proteinase 5 [KO:K01363] [EC:3.4.22.1]
CELE_W09G10.4  apd-3; AP-3 complex subunit delta [KO:K12396]
CELE_Y105E8A.9  apg-1; AP-1 complex subunit gamma [KO:K12391]
CELE_Y105E8B.9  Y105E8B.9; Beta-glucuronidase [KO:K01195] [EC:3.2.1.31]
CELE_Y110A7A.12  spe-5; V-type proton ATPase subunit B 2 [KO:K02147]
CELE_Y16B4A.2  Y16B4A.2; Carboxypeptidase [KO:K13289] [EC:3.4.16.5]
CELE_Y24F12A.2  ragc-1; Ras-related GTP-binding protein C [KO:K16186]
CELE_Y37E11B.3  blos-7; BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein [KO:K20820]
CELE_Y38F2AL.3  vha-11; V-type proton ATPase subunit C [KO:K02148]
CELE_Y38F2AL.4  vha-3; V-type proton ATPase 16 kDa proteolipid subunit 2/3 [KO:K02155]
CELE_Y40D12A.2  ctsa-4.2; Carboxypeptidase [KO:K13289] [EC:3.4.16.5]
CELE_Y43F4B.7  slc-36.1; Amino acid transporter transmembrane domain-containing protein [KO:K14209]
CELE_Y47D3A.17  obr-1; Oxysterol-binding protein [KO:K20456]
CELE_Y48G8AL.14  aps-3; AP complex mu/sigma subunit domain-containing protein [KO:K12399]
CELE_Y49A3A.2  vha-13; V-type proton ATPase catalytic subunit A [KO:K02145] [EC:7.1.2.2]
CELE_Y49E10.20  scav-3; Sensory neuron membrane protein 2 [KO:K12384]
CELE_Y4C6B.6  gba-4; Putative glucosylceramidase 4 [KO:K01201] [EC:3.2.1.45]
CELE_Y50E8A.16  haf-7; HAlF transporter (PGP related) [KO:K05656]
CELE_Y51H1A.2  cup-14; RUN domain-containing protein [KO:K23282]
CELE_Y53G8AR.7  mfsd-8.3; Major facilitator superfamily (MFS) profile domain-containing protein [KO:K12307]
CELE_Y54F10AM.10  rbc-2; WD_REPEATS_REGION domain-containing protein [KO:K24738]
CELE_Y55H10A.1  vha-19; V-type proton ATPase subunit S1 [KO:K03662]
CELE_Y57G11C.13  arl-8; ADP-ribosylation factor-like protein 8B [KO:K07955]
CELE_Y69A2AR.4  smf-3; NRAMP-like transporter smf-3 [KO:K21398]
CELE_Y69A2AR.6  vamp-7; V-SNARE coiled-coil homology domain-containing protein [KO:K08512]
CELE_Y71H2B.10  apb-1; AP complex subunit beta [KO:K11825]
CELE_Y73B6BL.30  blos-2; Biogenesis of lysosome-related organelles complex 1 subunit 2 [KO:K16750]
CELE_Y76A2B.6  scav-2; SCAVenger receptor (CD36 family) related [KO:K12384]
CELE_Y87G2A.19  Y87G2A.19; LITAF domain-containing protein [KO:K19363]
CELE_Y97E10AR.7  lmtr-2; Ragulator complex protein LAMTOR2 homolog [KO:K20398]
CELE_ZC190.1  cln-3.3; Battenin [KO:K12389]
CELE_ZK1128.8  vps-29; Vacuolar protein sorting-associated protein 29 [KO:K18467]
CELE_ZK384.3  asp-18; Peptidase A1 domain-containing protein [KO:K01379] [EC:3.4.23.5]
CELE_ZK455.4  asm-2; Sphingomyelin phosphodiesterase 2 [KO:K12350] [EC:3.1.4.12]
CELE_ZK484.2  haf-9; ABC-type antigen peptide transporter [KO:K05656]
CELE_ZK6.7  lipl-5; Lipase lipl-5 [KO:K01052] [EC:3.1.1.13]
CELE_ZK637.8  unc-32; V-type proton ATPase 116 kDa subunit a 1 [KO:K02154]
CELE_ZK809.4  ent-1; Equilibrative nucleoside transporter 3 [KO:K15014]
CELE_ZK970.4  vha-9; putative V-type proton ATPase subunit F [KO:K02151]
Compound
C00002  ATP
C00008  ADP
Reference
PMID:12628346
  Authors
Eskelinen EL, Tanaka Y, Saftig P
  Title
At the acidic edge: emerging functions for lysosomal membrane proteins.
  Journal
Trends Cell Biol 13:137-45 (2003)
DOI:10.1016/S0962-8924(03)00005-9
Reference
PMID:1883197
  Authors
Neufeld EF
  Title
Lysosomal storage diseases.
  Journal
Annu Rev Biochem 60:257-80 (1991)
DOI:10.1146/annurev.bi.60.070191.001353
Reference
PMID:2943218
  Authors
von Figura K, Hasilik A
  Title
Lysosomal enzymes and their receptors.
  Journal
Annu Rev Biochem 55:167-93 (1986)
DOI:10.1146/annurev.bi.55.070186.001123
Reference
PMID:15987739
  Authors
Janvier K, Bonifacino JS
  Title
Role of the endocytic machinery in the sorting of lysosome-associated membrane proteins.
  Journal
Mol Biol Cell 16:4231-42 (2005)
DOI:10.1091/mbc.E05-03-0213
Reference
PMID:18635948
  Authors
Vergarajauregui S, Puertollano R
  Title
Mucolipidosis type IV: the importance of functional lysosomes for efficient autophagy.
  Journal
Autophagy 4:832-4 (2008)
DOI:10.4161/auto.6567
Reference
PMID:34249946
  Authors
Jaskolka MC, Winkley SR, Kane PM
  Title
RAVE and Rabconnectin-3 Complexes as Signal Dependent Regulators of Organelle Acidification.
  Journal
Front Cell Dev Biol 9:698190 (2021)
DOI:10.3389/fcell.2021.698190
Reference
PMID:34646033
  Authors
Majdoul S, Compton AA
  Title
Lessons in self-defence: inhibition of virus entry by intrinsic immunity.
  Journal
Nat Rev Immunol 22:339-352 (2022)
DOI:10.1038/s41577-021-00626-8
Reference
PMID:19672277
  Authors
Saftig P, Klumperman J
  Title
Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function.
  Journal
Nat Rev Mol Cell Biol 10:623-35 (2009)
DOI:10.1038/nrm2745
Reference
PMID:31611045
  Authors
Savini M, Zhao Q, Wang MC
  Title
Lysosomes: Signaling Hubs for Metabolic Sensing and Longevity.
  Journal
Trends Cell Biol 29:876-887 (2019)
DOI:10.1016/j.tcb.2019.08.008
Reference
PMID:33433692
  Authors
Meyer-Schwesinger C
  Title
Lysosome function in glomerular health and disease.
  Journal
Cell Tissue Res 385:371-392 (2021)
DOI:10.1007/s00441-020-03375-7
Reference
PMID:34345172
  Authors
Allemailem KS, Almatroudi A, Alrumaihi F, Almatroodi SA, Alkurbi MO, Basfar GT, Rahmani AH, Khan AA
  Title
Novel Approaches of Dysregulating Lysosome Functions in Cancer Cells by Specific Drugs and Its Nanoformulations: A Smart Approach of Modern Therapeutics.
  Journal
Int J Nanomedicine 16:5065-5098 (2021)
DOI:10.2147/IJN.S321343
Reference
PMID:36096887
  Authors
Zhang W, Yang X, Li Y, Yu L, Zhang B, Zhang J, Cho WJ, Venkatarangan V, Chen L, Burugula BB, Bui S, Wang Y, Duan C, Kitzman JO, Li M
  Title
GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway.
  Journal
Nat Commun 13:5351 (2022)
DOI:10.1038/s41467-022-33025-1
Reference
PMID:38357444
  Authors
Liu Q, Wang W, Xu L, Zhang Q, Wang H
  Title
The host mannose-6-phosphate pathway and viral infection.
  Journal
Front Cell Infect Microbiol 14:1349221 (2024)
DOI:10.3389/fcimb.2024.1349221
Reference
PMID:38711187
  Authors
He Y, Fan Y, Ahmadpoor X, Wang Y, Li ZA, Zhu W, Lin H
  Title
Targeting lysosomal quality control as a therapeutic strategy against aging and diseases.
  Journal
Med Res Rev 44:2472-2509 (2024)
DOI:10.1002/med.22047
Reference
PMID:40759742
  Authors
Radulovic M, Yang C, Stenmark H
  Title
Lysosomal membrane homeostasis and its importance in physiology and disease.
  Journal
Nat Rev Mol Cell Biol 27:71-87 (2026)
DOI:10.1038/s41580-025-00873-w
Reference
PMID:41214333
  Authors
Watson ET, Wegeng WR, Aravani S, Ernst AM, von Blume J
  Title
Mechanistic insights into cargo sorting and export from the Golgi apparatus.
  Journal
Nat Rev Mol Cell Biol 26:940-956 (2025)
DOI:10.1038/s41580-025-00907-3
Related
pathway
cel00511  Other glycan degradation
cel00531  Glycosaminoglycan degradation
cel04130  SNARE interactions in vesicular transport
cel04140  Autophagy - animal
cel04144  Endocytosis
cel04145  Phagocytosis
cel04150  mTOR signaling pathway
cel04620  Toll-like receptor signaling pathway
KO pathway
ko04142   

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