KEGG   PATHWAY: cln00230
Entry
cln00230                    Pathway                                
Name
Purine metabolism - Campylobacter lari NCTC 11845
Class
Metabolism; Nucleotide metabolism
Pathway map
cln00230  Purine metabolism
cln00230

Module
cln_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cln00230]
cln_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cln00230]
cln_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cln00230]
cln_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cln00230]
cln_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cln00230]
Other DBs
GO: 0006163 0042278
Organism
Campylobacter lari NCTC 11845 [GN:cln]
Gene
UPTC3659_0005  ureA; fusion of urease beta and gamma subunits [KO:K14048] [EC:3.5.1.5]
UPTC3659_0006  ureB; urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
UPTC3659_0029  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
UPTC3659_0030  nrdA; aerobic ribonucleoside-diphosphate reductase Ia, B1 protein subunit NrdA [KO:K00525] [EC:1.17.4.1]
UPTC3659_0066  nrdD; anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
UPTC3659_0070  purM; phosphoribosylformylglycinamide cyclo-ligase [KO:K01933] [EC:6.3.3.1]
UPTC3659_0193  gppA; guanosine-5'-triphosphate, 3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
UPTC3659_0262  sat; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
UPTC3659_0276  [KO:K15778] [EC:5.4.2.8 5.4.2.2]
UPTC3659_0329  cysD; sulfate adenylyltransferase, subunit CysD [KO:K00957] [EC:2.7.7.4]
UPTC3659_0330  cysN; sulfate adenylyltransferase, GTPase subunit CysN [KO:K00956] [EC:2.7.7.4]
UPTC3659_0332  [KO:K00860] [EC:2.7.1.25]
UPTC3659_0384  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
UPTC3659_0449  [KO:K00769] [EC:2.4.2.22]
UPTC3659_0530  guaA; GMP synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
UPTC3659_0533  purD; phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
UPTC3659_0577  purH; AICAR transformylase / IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
UPTC3659_0579  purL; phosphoribosylformylglycinamidine synthase PurLQS, PurL subunit [KO:K23269]
UPTC3659_0711  spoT; ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3' pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
UPTC3659_0744  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
UPTC3659_0784  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
UPTC3659_0814  purQ; phosphoribosylformylglycinamidine synthase PurLQS, glutaminase subunit PurQ [KO:K23265]
UPTC3659_0815  purS; phosphoribosylformylglycinamidine synthase PurLQS, PurS subunit [KO:K23264]
UPTC3659_0816  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
UPTC3659_1138  [KO:K19710] [EC:2.7.7.53]
UPTC3659_1143  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
UPTC3659_1215  purE; 5-aminoimidazole ribonucleotide (AIR) carboxylase [KO:K01588] [EC:5.4.99.18]
UPTC3659_1304  gmk; deoxyguanylate kinase / guanylate kinase [KO:K00942] [EC:2.7.4.8]
UPTC3659_1316  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
UPTC3659_1376  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
UPTC3659_1490  prs; ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
UPTC3659_1500  [KO:K01519] [EC:3.6.1.66]
UPTC3659_1544  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
UPTC3659_1592  surE; broad specificity 5'(3')-nucleotidase and polyphosphatase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
UPTC3659_1622  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
UPTC3659_1681  purN; phosphoribosylglycinamide formyltransferase 1 [KO:K11175] [EC:2.1.2.2]
UPTC3659_1720  nrdB; aerobic ribonucleoside-diphosphate reductase Ia, B2 protein subunit NrdB [KO:K00526] [EC:1.17.4.1]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cln00030  Pentose phosphate pathway
cln00220  Arginine biosynthesis
cln00250  Alanine, aspartate and glutamate metabolism
cln00260  Glycine, serine and threonine metabolism
cln00340  Histidine metabolism
cln00630  Glyoxylate and dicarboxylate metabolism
cln00730  Thiamine metabolism
cln00740  Riboflavin metabolism
cln00790  Folate biosynthesis
KO pathway
ko00230   

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