KEGG   PATHWAY: crb00290
Entry
crb00290                    Pathway                                
Name
Valine, leucine and isoleucine biosynthesis - Capsella rubella (pink shepherd's-purse)
Class
Metabolism; Amino acid metabolism
Pathway map
crb00290  Valine, leucine and isoleucine biosynthesis
crb00290

Module
crb_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:crb00290]
crb_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:crb00290]
crb_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:crb00290]
Other DBs
GO: 0009097 0009098 0009099
Organism
Capsella rubella (pink shepherd's-purse) [GN:crb]
Gene
17891676  threonine dehydratase biosynthetic, chloroplastic [KO:K01754] [EC:4.3.1.19]
17880239  3-isopropylmalate dehydratase large subunit, chloroplastic [KO:K01703] [EC:4.2.1.33 4.2.1.35]
17889552  3-isopropylmalate dehydratase small subunit 3 [KO:K01704] [EC:4.2.1.33 4.2.1.35]
17895032  3-isopropylmalate dehydrogenase 2, chloroplastic [KO:K00052] [EC:1.1.1.85]
17894397  3-isopropylmalate dehydrogenase 2, chloroplastic [KO:K00052] [EC:1.1.1.85]
17887103  acetolactate synthase, chloroplastic [KO:K01652] [EC:2.2.1.6]
17881944  acetolactate synthase small subunit 1, chloroplastic [KO:K01653] [EC:2.2.1.6]
17888744  acetolactate synthase small subunit 2, chloroplastic isoform X2 [KO:K01653] [EC:2.2.1.6]
17884982  ketol-acid reductoisomerase, chloroplastic [KO:K00053] [EC:1.1.1.86]
17891932  dihydroxy-acid dehydratase, chloroplastic [KO:K01687] [EC:4.2.1.9]
17887394  branched-chain-amino-acid aminotransferase 3, chloroplastic [KO:K00826] [EC:2.6.1.42]
17897778  branched-chain-amino-acid aminotransferase 6 [KO:K00826] [EC:2.6.1.42]
17887752  branched-chain-amino-acid aminotransferase 1, mitochondrial [KO:K00826] [EC:2.6.1.42]
17900879  branched-chain-amino-acid aminotransferase 2, chloroplastic [KO:K00826] [EC:2.6.1.42]
17896929  branched-chain-amino-acid aminotransferase 1, mitochondrial isoform X2 [KO:K00826] [EC:2.6.1.42]
17900156  putative branched-chain-amino-acid aminotransferase 7 [KO:K00826] [EC:2.6.1.42]
17894344  2-isopropylmalate synthase 2, chloroplastic isoform X1 [KO:K01649] [EC:2.3.3.13]
17899709  2-isopropylmalate synthase 1, chloroplastic [KO:K01649] [EC:2.3.3.13]
17889879  3-isopropylmalate dehydratase small subunit 1 [KO:K21359] [EC:4.2.1.33 4.2.1.170]
17886442  3-isopropylmalate dehydratase small subunit 2 [KO:K21359] [EC:4.2.1.33 4.2.1.170]
17895092  3-isopropylmalate dehydratase small subunit 2 [KO:K21359] [EC:4.2.1.33 4.2.1.170]
17884309  3-isopropylmalate dehydrogenase 3, chloroplastic isoform X1 [KO:K21360] [EC:1.1.1.85 1.1.1.-]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00109  2-Oxobutanoate
C00123  L-Leucine
C00141  3-Methyl-2-oxobutanoic acid
C00183  L-Valine
C00188  L-Threonine
C00233  4-Methyl-2-oxopentanoate
C00407  L-Isoleucine
C00671  (S)-3-Methyl-2-oxopentanoic acid
C02226  2-Methylmaleate
C02504  alpha-Isopropylmalate
C02612  (R)-2-Methylmalate
C02631  2-Isopropylmaleate
C04181  3-Hydroxy-3-methyl-2-oxobutanoic acid
C04236  (2S)-2-Isopropyl-3-oxosuccinate
C04272  (R)-2,3-Dihydroxy-3-methylbutanoate
C04411  (2R,3S)-3-Isopropylmalate
C06006  (S)-2-Aceto-2-hydroxybutanoate
C06007  (R)-2,3-Dihydroxy-3-methylpentanoate
C06010  (S)-2-Acetolactate
C06032  D-erythro-3-Methylmalate
C14463  (R)-3-Hydroxy-3-methyl-2-oxopentanoate
Reference
  Authors
Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G.
  Title
Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway.
  Journal
J Bacteriol 186:5400-9 (2004)
DOI:10.1128/JB.186.16.5400-5409.2004
Related
pathway
crb00260  Glycine, serine and threonine metabolism
crb00280  Valine, leucine and isoleucine degradation
crb00620  Pyruvate metabolism
KO pathway
ko00290   
LinkDB

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