KEGG   PATHWAY: dha00010
Entry
dha00010                    Pathway                                
Name
Glycolysis / Gluconeogenesis - Debaryomyces hansenii
Description
Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds of glycerone-P, glyceraldehyde-3P, glycerate-3P, phosphoenolpyruvate, and pyruvate [MD:M00001]. Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate [MD:M00307]. When the enzyme genes of this pathway are examined in completely sequenced genomes, the reaction steps of three-carbon compounds from glycerone-P to pyruvate form a conserved core module [MD:M00002], which is found in almost all organisms and which sometimes contains operon structures in bacterial genomes. Gluconeogenesis is a synthesis pathway of glucose from noncarbohydrate precursors. It is essentially a reversal of glycolysis with minor variations of alternative paths [MD:M00003].
Class
Metabolism; Carbohydrate metabolism
Pathway map
dha00010  Glycolysis / Gluconeogenesis
dha00010

Module
dha_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:dha00010]
dha_M00002  Glycolysis, core module involving three-carbon compounds [PATH:dha00010]
dha_M00003  Gluconeogenesis, oxaloacetate => fructose-6P [PATH:dha00010]
dha_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:dha00010]
Other DBs
GO: 0006096 0006094
Organism
Debaryomyces hansenii [GN:dha]
Gene
DEHA2F13992g  DEHA2F13992p [KO:K00844] [EC:2.7.1.1]
DEHA2E06556g  DEHA2E06556p [KO:K00844] [EC:2.7.1.1]
DEHA2F24618g  DEHA2F24618p [KO:K00844] [EC:2.7.1.1]
DEHA2F13156g  DEHA2F13156p [KO:K01810] [EC:5.3.1.9]
DEHA2D10186g  DEHA2D10186p [KO:K00850] [EC:2.7.1.11]
DEHA2G20768g  DEHA2G20768p [KO:K00850] [EC:2.7.1.11]
DEHA2F01100g  DEHA2F01100p [KO:K03841] [EC:3.1.3.11]
DEHA2D17798g  DEHA2D17798p [KO:K01624] [EC:4.1.2.13]
DEHA2F06754g  DEHA2F06754p [KO:K01803] [EC:5.3.1.1]
DEHA2F04796g  DEHA2F04796p [KO:K00134] [EC:1.2.1.12]
DEHA2F15202g  DEHA2F15202p [KO:K00927] [EC:2.7.2.3]
DEHA2E21054g  DEHA2E21054p [KO:K01834] [EC:5.4.2.11]
DEHA2D12760g  DEHA2D12760p [KO:K01834] [EC:5.4.2.11]
DEHA2D02112g  DEHA2D02112p [KO:K01689] [EC:4.2.1.11]
DEHA2G14058g  DEHA2G14058p [KO:K01689] [EC:4.2.1.11]
DEHA2D11044g  DEHA2D11044p [KO:K00873] [EC:2.7.1.40]
DEHA2G12870g  DEHA2G12870p [KO:K00161] [EC:1.2.4.1]
DEHA2C09152g  DEHA2C09152p [KO:K00162] [EC:1.2.4.1]
DEHA2A05654g  DEHA2A05654p [KO:K00627] [EC:2.3.1.12]
DEHA2C01342g  DEHA2C01342p [KO:K00382] [EC:1.8.1.4]
DEHA2G18348g  DEHA2G18348p [KO:K01568] [EC:4.1.1.1]
DEHA2D16984g  DEHA2D16984p [KO:K01568] [EC:4.1.1.1]
DEHA2B03872g  DEHA2B03872p [KO:K01568] [EC:4.1.1.1]
DEHA2G05808g  DEHA2G05808p [KO:K00121] [EC:1.1.1.284 1.1.1.1]
DEHA2F03938g  DEHA2F03938p [KO:K13953] [EC:1.1.1.1]
DEHA2C00880g  DEHA2C00880p [KO:K13953] [EC:1.1.1.1]
DEHA2G21032g  DEHA2G21032p [KO:K13953] [EC:1.1.1.1]
DEHA2D00748g  DEHA2D00748p [KO:K13953] [EC:1.1.1.1]
DEHA2C04510g  DEHA2C04510p [KO:K00002] [EC:1.1.1.2]
DEHA2C17666g  DEHA2C17666p [KO:K00002] [EC:1.1.1.2]
DEHA2C04488g  DEHA2C04488p [KO:K00002] [EC:1.1.1.2]
DEHA2B00286g  DEHA2B00286p [KO:K00002] [EC:1.1.1.2]
DEHA2G03740g  DEHA2G03740p [KO:K00128] [EC:1.2.1.3]
DEHA2C01562g  DEHA2C01562p [KO:K00128] [EC:1.2.1.3]
DEHA2F00792g  DEHA2F00792p [KO:K00128] [EC:1.2.1.3]
DEHA2G09372g  DEHA2G09372p [KO:K00128] [EC:1.2.1.3]
DEHA2G22572g  DEHA2G22572p [KO:K00128] [EC:1.2.1.3]
DEHA2D12606g  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DEHA2E05676g  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
DEHA2C02464g  DEHA2C02464p [KO:K01784 K01785] [EC:5.1.3.2 5.1.3.3]
DEHA2D00902g  DEHA2D00902p [KO:K01785] [EC:5.1.3.3]
DEHA2C05258g  DEHA2C05258p [KO:K01835] [EC:5.4.2.2]
DEHA2F03036g  DEHA2F03036p [KO:K01835] [EC:5.4.2.2]
DEHA2E12892g  DEHA2E12892p [KO:K01792] [EC:5.1.3.15]
DEHA2E18568g  DEHA2E18568p [KO:K01610] [EC:4.1.1.49]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00031  D-Glucose
C00033  Acetate
C00036  Oxaloacetate
C00068  Thiamin diphosphate
C00074  Phosphoenolpyruvate
C00084  Acetaldehyde
C00085  D-Fructose 6-phosphate
C00103  D-Glucose 1-phosphate
C00111  Glycerone phosphate
C00118  D-Glyceraldehyde 3-phosphate
C00186  (S)-Lactate
C00197  3-Phospho-D-glycerate
C00221  beta-D-Glucose
C00236  3-Phospho-D-glyceroyl phosphate
C00267  alpha-D-Glucose
C00354  D-Fructose 1,6-bisphosphate
C00469  Ethanol
C00631  2-Phospho-D-glycerate
C00668  alpha-D-Glucose 6-phosphate
C01159  2,3-Bisphospho-D-glycerate
C01172  beta-D-Glucose 6-phosphate
C01451  Salicin
C05125  2-(alpha-Hydroxyethyl)thiamine diphosphate
C06186  Arbutin
C06187  Arbutin 6-phosphate
C06188  Salicin 6-phosphate
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16255  [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine
Reference
  Authors
Nishizuka Y (ed).
  Title
[Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1980)
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
  Authors
Michal G.
  Title
Biochemical Pathways
  Journal
Wiley (1999)
Related
pathway
dha00020  Citrate cycle (TCA cycle)
dha00030  Pentose phosphate pathway
dha00500  Starch and sucrose metabolism
dha00620  Pyruvate metabolism
dha00640  Propanoate metabolism
dha00710  Carbon fixation by Calvin cycle
KO pathway
ko00010   
LinkDB

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