KEGG   PATHWAY: dme00630
Entry
dme00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Drosophila melanogaster (fruit fly)
Class
Metabolism; Carbohydrate metabolism
Pathway map
dme00630  Glyoxylate and dicarboxylate metabolism
dme00630

Module
dme_M00621  Glycine cleavage system [PATH:dme00630]
Other DBs
GO: 0046487 0043648
Organism
Drosophila melanogaster (fruit fly) [GN:dme]
Gene
Dmel_CG10748  CG10748; uncharacterized protein [KO:K00026] [EC:1.1.1.37]
Dmel_CG10749  CG10749; uncharacterized protein [KO:K00026] [EC:1.1.1.37]
Dmel_CG10932  Acat1; Acetyl-CoA acetyltransferase 1, isoform B [KO:K00626] [EC:2.3.1.9]
Dmel_CG11241  CG11241; uncharacterized protein, isoform C [KO:K00827] [EC:2.6.1.44 2.6.1.40]
Dmel_CG11291  CG11291; uncharacterized protein [KO:K19269] [EC:3.1.3.18 3.1.3.48]
Dmel_CG1236  CG1236; uncharacterized protein [KO:K00049] [EC:1.1.1.79 1.1.1.81]
Dmel_CG14740  CG14740; uncharacterized protein [KO:K01647] [EC:2.3.3.1]
Dmel_CG1743  Gs2; glutamine synthetase 2, isoform E [KO:K01915] [EC:6.3.1.2]
Dmel_CG18003  Hao; hydroxyacid oxidase [KO:K11517] [EC:1.1.3.15]
Dmel_CG2227  Gip; GIP-like [KO:K01816] [EC:5.3.1.22]
Dmel_CG2718  Gs1; glutamine synthetase 1, isoform D [KO:K01915] [EC:6.3.1.2]
Dmel_CG3011  Shmt; serine hydroxymethyl transferase, isoform B [KO:K00600] [EC:2.1.2.1]
Dmel_CG32487  CG32487; uncharacterized protein [KO:K19269] [EC:3.1.3.18 3.1.3.48]
Dmel_CG32488  CG32488; uncharacterized protein, isoform B [KO:K19269] [EC:3.1.3.18 3.1.3.48]
Dmel_CG3861  kdn; knockdown, isoform A [KO:K01647] [EC:2.3.3.1]
Dmel_CG3926  Agxt; Alanine-glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
Dmel_CG3999  CG3999; uncharacterized protein, isoform B [KO:K00281] [EC:1.4.4.2]
Dmel_CG4706  mAcon2; mitochondrial aconitase 2 [KO:K01681] [EC:4.2.1.3]
Dmel_CG4900  Irp-1A; iron regulatory protein 1A [KO:K01681] [EC:4.2.1.3]
Dmel_CG5362  Mdh1; malate dehydrogenase 1, isoform B [KO:K00025] [EC:1.1.1.37]
Dmel_CG5567  CG5567; uncharacterized protein [KO:K19269] [EC:3.1.3.18 3.1.3.48]
Dmel_CG5577  CG5577; uncharacterized protein, isoform B [KO:K19269] [EC:3.1.3.18 3.1.3.48]
Dmel_CG6342  Irp-1B; iron regulatory protein 1B [KO:K01681] [EC:4.2.1.3]
Dmel_CG6415  CG6415; uncharacterized protein [KO:K00605] [EC:2.1.2.10]
Dmel_CG6871  Cat; catalase [KO:K03781] [EC:1.11.1.6]
Dmel_CG7430  CG7430; uncharacterized protein, isoform B [KO:K00382] [EC:1.8.1.4]
Dmel_CG7758  ppl; pumpless [KO:K02437]
Dmel_CG7998  Mdh2; malate dehydrogenase 2 [KO:K00026] [EC:1.1.1.37]
Dmel_CG9149  Acat2; Acetyl-CoA acetyltransferase 2 [KO:K00626] [EC:2.3.1.9]
Dmel_CG9244  mAcon1; mitochondrial aconitase 1, isoform E [KO:K01681] [EC:4.2.1.3]
Dmel_CG9314  CatB; catalase B, isoform C [KO:K03781] [EC:1.11.1.6]
Dmel_CG9390  AcCoAS; acetyl coenzyme A synthase, isoform D [KO:K01895] [EC:6.2.1.1]
Dmel_CG9542  KFase; kynurenine formamidase, isoform B [KO:K01432] [EC:3.5.1.9]
Dmel_CG9886  CG9886; uncharacterized protein, isoform B [KO:K11529] [EC:2.7.1.165]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00049  L-Aspartate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C05840  Iminoaspartate
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C19838  D-erythro-3-Hydroxyaspartate
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
dme00010  Glycolysis / Gluconeogenesis
dme00020  Citrate cycle (TCA cycle)
dme00030  Pentose phosphate pathway
dme00053  Ascorbate and aldarate metabolism
dme00071  Fatty acid degradation
dme00230  Purine metabolism
dme00250  Alanine, aspartate and glutamate metabolism
dme00260  Glycine, serine and threonine metabolism
dme00270  Cysteine and methionine metabolism
dme00620  Pyruvate metabolism
dme00750  Vitamin B6 metabolism
dme00910  Nitrogen metabolism
KO pathway
ko00630   

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