KEGG   PATHWAY: dml00230
Entry
dml00230                    Pathway                                
Name
Purine metabolism - Desulfococcus multivorans
Class
Metabolism; Nucleotide metabolism
Pathway map
dml00230  Purine metabolism
dml00230

Module
dml_M00005  PRPP biosynthesis, ribose-5P => PRPP [PATH:dml00230]
dml_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:dml00230]
dml_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:dml00230]
dml_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:dml00230]
dml_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:dml00230]
Other DBs
GO: 0006163 0042278
Organism
Desulfococcus multivorans [GN:dml]
Gene
Dmul_01280  ham; Ham: nucleoside-triphosphatase [KO:K01519] [EC:3.6.1.66]
Dmul_03190  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Dmul_03310  ade1; Ade1: adenine deaminase [KO:K01486] [EC:3.5.4.2]
Dmul_05590  purF; PurF: amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Dmul_06420  vrlG; VrlG: virulence associated protein [KO:K00764] [EC:2.4.2.14]
Dmul_08800  prs; Prs: ribose-phosphate pyrophosphokinase (RPPK) [KO:K00948] [EC:2.7.6.1]
Dmul_08980  gmk; Gmk: guanylate kinase [KO:K00942] [EC:2.7.4.8]
Dmul_09350  ndk; Ndk: nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Dmul_10200  mazG; MazG: nucleotide pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
Dmul_12530  adk; Adk: adenylate kinase [KO:K00939] [EC:2.7.4.3]
Dmul_12670  purL; PurL: phosphoribosylformylglycinamidine synthase II [KO:K23270]
Dmul_12680  purQ; PurQ: phosphoribosylformylglycinamidine synthase I [KO:K23265]
Dmul_14170  guaC; GuaC: guanosine 5\'-monophosphate oxidoreductase [KO:K00364] [EC:1.7.1.7]
Dmul_14360  surE1; SurE1: nucleoside 5\'-monophosphate phosphohydrolase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Dmul_15200  purF; PurF: amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Dmul_15330  purN; PurN: phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Dmul_15380  relA; RelA: GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Dmul_19130  pgm; Pgm: phosphoglucomutase (glucose phosphomutase) [KO:K01835] [EC:5.4.2.2]
Dmul_20320  purB; PurB: adenylosuccinate lyase, subunit B [KO:K01756] [EC:4.3.2.2]
Dmul_20530  guaA; GuaA: GMP synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
Dmul_21400  dgt; Dgt: deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
Dmul_21790  purC; PurC: phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Dmul_22470  purA; PurA: adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
Dmul_22820  guaAB; GuaAB: GMP synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
Dmul_23950  [KO:K01768] [EC:4.6.1.1]
Dmul_24430  ade; Ade: adenine deaminase [KO:K01486] [EC:3.5.4.2]
Dmul_25210  guaB; GuaB: inosine-5\'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Dmul_25800  [KO:K01488] [EC:3.5.4.4]
Dmul_27020  sat1; Sat1: sulfate adenylyltransferase (ATP sulfurylase) [KO:K00958] [EC:2.7.7.4]
Dmul_27190  cya; Cya: predicted adenylate cyclase [KO:K05873] [EC:4.6.1.1]
Dmul_27550  prs; Prs: ribose-phosphate pyrophosphokinase (RPPK) [KO:K00948] [EC:2.7.6.1]
Dmul_28630  punA; PunA: purine nucleoside phosphorylase I, inosine and guanosine-specific [KO:K03783] [EC:2.4.2.1]
Dmul_28770  purH2; PurH2: phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Dmul_31150  sat2; Sat2: sulfate adenylyltransferase (ATP sulfurylase) [KO:K00958] [EC:2.7.7.4]
Dmul_31270  gpt; Gpt: xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
Dmul_31510  [KO:K01129] [EC:3.1.5.1]
Dmul_32950  nrdD; NrdD: anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
Dmul_34490  surE2; SurE2: nucleoside 5\'-monophosphate phosphohydrolase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Dmul_35110  cpkA; CpkA: carbamate kinase [KO:K00926] [EC:2.7.2.2]
Dmul_35670  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Dmul_36840  xdhA; XdhA: predicted xanthine dehydrogenase, molybdenum-binding subunit [KO:K13482] [EC:1.17.1.4]
Dmul_36850  xdhC; XdhC: predicted xanthine dehydrogenase, iron-sulfur-binding subunit [KO:K13481] [EC:1.17.1.4]
Dmul_37360  purD; PurD: phosphoribosylamine--glycine ligase (glycinamide ribonucleotide synthetase) [KO:K01945] [EC:6.3.4.13]
Dmul_37510  hcrC; HcrC: 4-hydroxybenzoyl-CoA reductase, subunit gamma [KO:K13483]
Dmul_37530  hcrB; HcrB: 4-hydroxybenzoyl-CoA reductase, subunit beta [KO:K11178] [EC:1.17.1.4]
Dmul_37930  hpt; Hpt: hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Dmul_38930  nrdZ; NrdZ: ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
Dmul_38990  purM; PurM: phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Dmul_39060  algC; AlgC: phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
dml00030  Pentose phosphate pathway
dml00220  Arginine biosynthesis
dml00250  Alanine, aspartate and glutamate metabolism
dml00260  Glycine, serine and threonine metabolism
dml00340  Histidine metabolism
dml00630  Glyoxylate and dicarboxylate metabolism
dml00730  Thiamine metabolism
dml00740  Riboflavin metabolism
dml00790  Folate biosynthesis
KO pathway
ko00230   

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