KEGG   PATHWAY: dsi00053
Entry
dsi00053                    Pathway                                
Name
Ascorbate and aldarate metabolism - Drosophila simulans
Class
Metabolism; Carbohydrate metabolism
Pathway map
dsi00053  Ascorbate and aldarate metabolism
dsi00053

Other DBs
GO: 0019852 0019577 0019572
Organism
Drosophila simulans [GN:dsi]
Gene
Dsimw501_GD13103  Dsim_GD13103; uncharacterized protein [KO:K00012] [EC:1.1.1.22]
Dsimw501_GD24083  Dsim_GD24083; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD24084  Dsim_GD24084; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD12307  Dsim_GD12307; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD21706  Dsim_GD21706; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD25513  Dsim_GD25513; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD23396  Dsim_GD23396; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD23245  Dsim_GD23245; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD16447  Dsim_GD16447; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD12034  Dsim_GD12034; uncharacterized protein, isoform B [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD18734  Dsim_GD18734; uncharacterized protein, isoform B [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD20680  Dsim_GD20680; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD20681  Dsim_GD20681; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD20683  Dsim_GD20683; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD20684  Dsim_GD20684; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD20686  Dsim_GD20686; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD23454  Dsim_GD23454; uncharacterized protein, isoform A [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD18859  Dsim_GD18859; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD24158  Dsim_GD24158; uncharacterized protein, isoform B [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD24159  Dsim_GD24159; uncharacterized protein, isoform C [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD24160  Dsim_GD24160; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD29191  Dsim_GD29191; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD20543  Dsim_GD20543; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD25117  Dsim_GD25117; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD25217  Dsim_GD25217; uncharacterized protein, isoform B [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD25218  Dsim_GD25218; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD27744  Dsim_GD27744; uncharacterized protein [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD19978  Dsim_GD19978; uncharacterized protein, isoform B [KO:K00699] [EC:2.4.1.17]
Dsimw501_GD25338  Dsim_GD25338; uncharacterized protein, isoform C [KO:K01195] [EC:3.2.1.31]
Dsimw501_GD28077  Dsim_GD28077; uncharacterized protein [KO:K01195] [EC:3.2.1.31]
Dsimw501_GD14365  Dsim_GD14365; uncharacterized protein [KO:K00469] [EC:1.13.99.1]
Dsimw501_GD19441  Dsim_GD19441; uncharacterized protein [KO:K00002] [EC:1.1.1.2]
Dsimw501_GD23600  Dsim_GD23600; uncharacterized protein [KO:K00128] [EC:1.2.1.3]
Dsimw501_GD18107  Dsim_GD18107; uncharacterized protein, isoform A [KO:K00128] [EC:1.2.1.3]
Dsimw501_GD12292  Dsim_GD12292; uncharacterized protein [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
dsi00020  Citrate cycle (TCA cycle)
dsi00040  Pentose and glucuronate interconversions
dsi00051  Fructose and mannose metabolism
dsi00520  Amino sugar and nucleotide sugar metabolism
dsi00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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