KEGG   PATHWAY: ecj00670
Entry
ecj00670                    Pathway                                
Name
One carbon pool by folate - Escherichia coli K-12 W3110
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
ecj00670  One carbon pool by folate
ecj00670

Module
ecj_M00126  Tetrahydrofolate biosynthesis, GTP => THF [PATH:ecj00670]
ecj_M00555  Betaine biosynthesis, choline => betaine [PATH:ecj00670]
ecj_M00621  Glycine cleavage system [PATH:ecj00670]
Other DBs
GO: 0035999
Organism
Escherichia coli K-12 W3110 [GN:ecj]
Gene
JW0047  folA; dihydrofolate reductase [KO:K00287] [EC:1.5.1.3]
JW0112  lpd; lipoamide dehydrogenase, E3 component is part of three enzyme complexes [KO:K00382] [EC:1.8.1.4]
JW0253  mmuM; S-methylmethionine:homocysteine methyltransferase [KO:K00547] [EC:2.1.1.10]
JW0303  betA; choline dehydrogenase, a flavoprotein [KO:K00108] [EC:1.1.99.1]
JW0304  betB; betaine aldehyde dehydrogenase, NAD-dependent [KO:K00130] [EC:1.2.1.8]
JW0518  folD; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase and 5,10-methylene-tetrahydrofolate cyclohydrolase [KO:K01491] [EC:1.5.1.5 3.5.4.9]
JW1220  purU; formyltetrahydrofolate hydrolase [KO:K01433] [EC:3.5.1.10]
JW1598  folM; dihydrofolate reductase isozyme [KO:K13938] [EC:1.5.1.50 1.5.1.3]
JW2485  purN; phosphoribosylglycinamide formyltransferase 1 [KO:K11175] [EC:2.1.2.2]
JW2535  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
JW2795  thyA; thymidylate synthetase [KO:K00560] [EC:2.1.1.45]
JW2871  gcvP; glycine decarboxylase, PLP-dependent, subunit (protein P) of glycine cleavage complex [KO:K00281] [EC:1.4.4.2]
JW2872  gcvH; glycine cleavage complex lipoylprotein [KO:K02437]
JW2873  gcvT; aminomethyltransferase, tetrahydrofolate-dependent, subunit (T protein) of glycine cleavage complex [KO:K00605] [EC:2.1.2.10]
JW2879  ygfA; predicted ligase [KO:K01934] [EC:6.3.3.2]
JW2909  metK; methionine adenosyltransferase 1 [KO:K00789] [EC:2.5.1.6]
JW3913  metF; 5,10-methylenetetrahydrofolate reductase [KO:K00297] [EC:1.5.1.54]
JW3970  purH; fused IMP cyclohydrolase and phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
JW3979  metH; homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent [KO:K00548] [EC:2.1.1.13]
Compound
C00002  ATP
C00019  S-Adenosyl-L-methionine
C00021  S-Adenosyl-L-homocysteine
C00037  Glycine
C00065  L-Serine
C00073  L-Methionine
C00097  L-Cysteine
C00101  Tetrahydrofolate
C00114  Choline
C00143  5,10-Methylenetetrahydrofolate
C00155  L-Homocysteine
C00212  Adenosine
C00213  Sarcosine
C00234  10-Formyltetrahydrofolate
C00364  dTMP
C00365  dUMP
C00415  Dihydrofolate
C00440  5-Methyltetrahydrofolate
C00445  5,10-Methenyltetrahydrofolate
C00504  Folate
C00576  Betaine aldehyde
C00664  5-Formiminotetrahydrofolate
C00719  Betaine
C01026  N,N-Dimethylglycine
C02291  L-Cystathionine
C03479  Folinic acid
Related
pathway
ecj00260  Glycine, serine and threonine metabolism
ecj00270  Cysteine and methionine metabolism
ecj00790  Folate biosynthesis
KO pathway
ko00670   

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