KEGG   PATHWAY: hgl00040
Entry
hgl00040                    Pathway                                
Name
Pentose and glucuronate interconversions - Heterocephalus glaber (naked mole-rat)
Class
Metabolism; Carbohydrate metabolism
Pathway map
hgl00040  Pentose and glucuronate interconversions
hgl00040

Module
hgl_M00014  Glucuronate pathway (uronate pathway) [PATH:hgl00040]
hgl_M00129  Ascorbate biosynthesis, animals, glucose-1P => ascorbate [PATH:hgl00040]
Organism
Heterocephalus glaber (naked mole-rat) [GN:hgl]
Gene
101709573  Gusb; glucuronidase beta [KO:K01195] [EC:3.2.1.31]
101723147  klotho-like [KO:K14756] [EC:3.2.1.31]
101707823  Ugt1a6; UDP-glucuronosyltransferase 1-6 [KO:K00699] [EC:2.4.1.17]
101713955  Ugt2a1; UDP-glucuronosyltransferase 2A1 [KO:K00699] [EC:2.4.1.17]
101712271  UDP-glucuronosyltransferase 2B17-like [KO:K00699] [EC:2.4.1.17]
101711049  UDP-glucuronosyltransferase 2B15 [KO:K00699] [EC:2.4.1.17]
101711920  UDP-glucuronosyltransferase 2B17 [KO:K00699] [EC:2.4.1.17]
101698281  UDP-glucuronosyltransferase 2B17 [KO:K00699] [EC:2.4.1.17]
101710483  UDP-glucuronosyltransferase 1-1 [KO:K00699] [EC:2.4.1.17]
101699331  UDP-glucuronosyltransferase 1-8-like [KO:K00699] [EC:2.4.1.17]
101700403  UDP-glucuronosyltransferase 1-7-like [KO:K00699] [EC:2.4.1.17]
101722538  UDP-glucuronosyltransferase 1-9 [KO:K00699] [EC:2.4.1.17]
101697239  UDP-glucuronosyltransferase 1-10-like [KO:K00699] [EC:2.4.1.17]
101726266  Ugdh; UDP-glucose 6-dehydrogenase [KO:K00012] [EC:1.1.1.22]
101717993  Ugp2; UDP-glucose pyrophosphorylase 2 [KO:K00963] [EC:2.7.7.9]
101710959  Akr1a1; aldo-keto reductase family 1 member A1 [KO:K00002] [EC:1.1.1.2]
101708457  Cryl1; crystallin lambda 1 [KO:K13247] [EC:1.1.1.45]
101703922  ribulose-phosphate 3-epimerase-like [KO:K01783] [EC:5.1.3.1]
101698495  Rpe; ribulose-5-phosphate-3-epimerase [KO:K01783] [EC:5.1.3.1]
101712072  Xylb; xylulokinase [KO:K00854] [EC:2.7.1.17]
101706493  Akr1b10; aldo-keto reductase family 1 member B10 [KO:K00011] [EC:1.1.1.21]
101720124  Akr1b1; aldo-keto reductase family 1 member B [KO:K00011] [EC:1.1.1.21]
101705915  aldo-keto reductase family 1 member B10-like [KO:K00011] [EC:1.1.1.21]
101724611  Dcxr; dicarbonyl and L-xylulose reductase [KO:K03331] [EC:1.1.1.10]
101699735  Sord; sorbitol dehydrogenase [KO:K00008] [EC:1.1.1.14]
101713222  Dhdh; dihydrodiol dehydrogenase [KO:K00078] [EC:1.3.1.20 1.1.1.179]
101720549  Fggy; FGGY carbohydrate kinase domain containing [KO:K00875] [EC:2.7.1.47]
101708024  Ispd; isoprenoid synthase domain containing [KO:K21031] [EC:2.7.7.40]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00103  D-Glucose 1-phosphate
C00111  Glycerone phosphate
C00116  Glycerol
C00167  UDP-glucuronate
C00181  D-Xylose
C00191  D-Glucuronate
C00199  D-Ribulose 5-phosphate
C00204  2-Dehydro-3-deoxy-D-gluconate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00266  Glycolaldehyde
C00309  D-Ribulose
C00310  D-Xylulose
C00312  L-Xylulose
C00333  D-Galacturonate
C00379  Xylitol
C00433  2,5-Dioxopentanoate
C00470  Pectate
C00474  Ribitol
C00476  D-Lyxose
C00502  D-Xylonate
C00508  L-Ribulose
C00514  D-Mannonate
C00532  L-Arabitol
C00558  D-Tagaturonate
C00618  3-Dehydro-L-gulonate
C00714  Pectin
C00789  CDP-ribitol
C00800  L-Gulonate
C00817  D-Altronate
C00905  D-Fructuronate
C01068  D-Ribitol 5-phosphate
C01101  L-Ribulose 5-phosphate
C01508  L-Lyxose
C01904  D-Arabitol
C02266  D-Xylonolactone
C02273  Digalacturonate
C02426  L-Glyceraldehyde
C02753  D-Xylono-1,4-lactone
C03033  beta-D-Glucuronoside
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C04053  5-Dehydro-4-deoxy-D-glucuronate
C04349  (4S)-4,6-Dihydroxy-2,5-dioxohexanoate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C06118  4-(4-Deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate
C06441  L-Xylulose 1-phosphate
C14899  3-Dehydro-L-gulonate 6-phosphate
C15930  L-Galactonate
C20680  2-Dehydro-3-deoxy-L-galactonate
C22337  D-Ribulose 1-phosphate
C22712  4-Deoxy-L-threo-hex-4-enopyranuronate
Reference
  Authors
Yew WS, Gerlt JA.
  Title
Utilization of L-ascorbate by Escherichia coli K-12: assignments of functions to products of the yjf-sga and yia-sgb operons.
  Journal
J Bacteriol 184:302-6 (2002)
DOI:10.1128/JB.184.1.302-306.2002
Reference
  Authors
Yew WS, Akana J, Wise EL, Rayment I, Gerlt JA
  Title
Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: enhancing the promiscuous D-arabino-hex-3-ulose 6-phosphate synthase reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase.
  Journal
Biochemistry 44:1807-15 (2005)
DOI:10.1021/bi047815v
Reference
  Authors
Yasueda H, Kawahara Y, Sugimoto S.
  Title
Bacillus subtilis yckG and yckF encode two key enzymes of the ribulose monophosphate pathway used by methylotrophs, and yckH is required for their expression.
  Journal
J Bacteriol 181:7154-60 (1999)
DOI:10.1128/JB.181.23.7154-7160.1999
Reference
  Authors
Ibanez E, Gimenez R, Pedraza T, Baldoma L, Aguilar J, Badia J
  Title
Role of the yiaR and yiaS genes of Escherichia coli in metabolism of endogenously formed L-xylulose.
  Journal
J Bacteriol 182:4625-7 (2000)
DOI:10.1128/JB.182.16.4625-4627.2000
Reference
  Authors
Orita I, Yurimoto H, Hirai R, Kawarabayasi Y, Sakai Y, Kato N
  Title
The archaeon Pyrococcus horikoshii possesses a bifunctional enzyme for formaldehyde fixation via the ribulose monophosphate pathway.
  Journal
J Bacteriol 187:3636-42 (2005)
DOI:10.1128/JB.187.11.3636-3642.2005
Related
pathway
hgl00010  Glycolysis / Gluconeogenesis
hgl00020  Citrate cycle (TCA cycle)
hgl00030  Pentose phosphate pathway
hgl00052  Galactose metabolism
hgl00053  Ascorbate and aldarate metabolism
hgl00500  Starch and sucrose metabolism
hgl00520  Amino sugar and nucleotide sugar metabolism
hgl00561  Glycerolipid metabolism
hgl00562  Inositol phosphate metabolism
hgl00740  Riboflavin metabolism
KO pathway
ko00040   
LinkDB

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