PATHWAY: ko00040 Help
Entry
Name
Pentose and glucuronate interconversions
Class
Metabolism; Carbohydrate metabolism
BRITE hierarchy
Pathway map
ko00040 Pentose and glucuronate interconversions
Module
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:ko00040 ]
M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate [PATH:ko00040 ]
M00630 D-Galacturonate degradation (fungi), D-galacturonate => glycerol [PATH:ko00040 ]
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:ko00040 ]
M00994 UDP-GlcA biosynthesis, myo-inositol => GlcA => UDP-GlcA [PATH:ko00040 ]
Orthology
K00963 UGP2, galU, galF; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9 ]
K01815 kduI; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [EC:5.3.1.17 ]
K01820 rhaA; L-rhamnose isomerase / sugar isomerase [EC:5.3.1.14 5.3.1.-]
K03077 araD, ulaF, sgaE, sgbE; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4 ]
K03078 ulaD, sgaH, sgbH; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85 ]
K03079 ulaE, sgaU, sgbU; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22 ]
K14259 kdaD, xacE, kdxD; 2-dehydro-3-deoxy-D-arabinonate dehydratase [EC:4.2.1.141 ]
K14273 xdh; D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) [EC:1.1.1.179 ]
K18103 GAAC, LGA1; L-threo-3-deoxy-hexylosonate aldolase [EC:4.1.2.54 ]
K18106 GAAA; D-galacturonate reductase [EC:1.1.1.-]
K21681 bcs1; ribitol-5-phosphate 2-dehydrogenase (NADP+) / D-ribitol-5-phosphate cytidylyltransferase [EC:1.1.1.405 2.7.7.40 ]
K22187 xylA; alpha-ketoglutaric semialdehyde dehydrogenase [EC:1.2.1.-]
K22397 yjhH, yagE; 2-dehydro-3-deoxy-D-pentonate aldolase [EC:4.1.2.28 ]
K22933 lplD; galacturan 1,4-alpha-galacturonidase
K22935 XK1, psk; D-ribulokinase
K22994 pelX; pectate disaccharide-lyase
K24442 xacA; D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming)
K24443 xacC; D-xylono/L-arabinono-1,4-lactonase
K24707 E2.7.1.16; ribulokinase
K25879 LXRA; L-xylulose reductase
K25880 LADA; L-arabinitol 4-dehydrogenase
K25881 LARA; L-arabinose reductase
K26066 XYRB; D-xylose/L-arabinose reductase (NADPH)
K26933 kdgF; unsaturated pyranuronate lyase
Compound
C00204 2-Dehydro-3-deoxy-D-gluconate
C03826 2-Dehydro-3-deoxy-D-xylonate
C04053 5-Dehydro-4-deoxy-D-glucuronate
C04349 (4S)-4,6-Dihydroxy-2,5-dioxohexanoate
C04575 (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385 D-Glucuronate 1-phosphate
C06118 4-(4-Deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate
C14899 3-Dehydro-L-gulonate 6-phosphate
C20680 2-Dehydro-3-deoxy-L-galactonate
C22712 4-Deoxy-L-threo-hex-4-enopyranuronate
Reference
Authors
Yew WS, Gerlt JA.
Title
Utilization of L-ascorbate by Escherichia coli K-12: assignments of functions to products of the yjf-sga and yia-sgb operons.
Journal
Reference
Authors
Yew WS, Akana J, Wise EL, Rayment I, Gerlt JA
Title
Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: enhancing the promiscuous D-arabino-hex-3-ulose 6-phosphate synthase reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase.
Journal
Reference
Authors
Yasueda H, Kawahara Y, Sugimoto S.
Title
Bacillus subtilis yckG and yckF encode two key enzymes of the ribulose monophosphate pathway used by methylotrophs, and yckH is required for their expression.
Journal
Reference
Authors
Ibanez E, Gimenez R, Pedraza T, Baldoma L, Aguilar J, Badia J
Title
Role of the yiaR and yiaS genes of Escherichia coli in metabolism of endogenously formed L-xylulose.
Journal
Reference
Authors
Orita I, Yurimoto H, Hirai R, Kawarabayasi Y, Sakai Y, Kato N
Title
The archaeon Pyrococcus horikoshii possesses a bifunctional enzyme for formaldehyde fixation via the ribulose monophosphate pathway.
Journal
Related pathway
ko00010 Glycolysis / Gluconeogenesis
ko00053 Ascorbate and aldarate metabolism
ko00520 Amino sugar and nucleotide sugar metabolism
ko00562 Inositol phosphate metabolism