KEGG   PATHWAY: hgl00562
Entry
hgl00562                    Pathway                                
Name
Inositol phosphate metabolism - Heterocephalus glaber (naked mole-rat)
Class
Metabolism; Carbohydrate metabolism
Pathway map
hgl00562  Inositol phosphate metabolism
hgl00562

Module
hgl_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:hgl00562]
hgl_M00131  Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:hgl00562]
hgl_M00132  Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:hgl00562]
Other DBs
GO: 0006020
Organism
Heterocephalus glaber (naked mole-rat) [GN:hgl]
Gene
101720820  Pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
101698768  Mtm1; myotubularin 1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
101699372  Mtmr1; myotubularin related protein 1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
101718842  Mtmr2; myotubularin related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
101710657  Mtmr3; myotubularin related protein 3 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
101712041  Mtmr4; myotubularin related protein 4 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
101699227  Mtmr7; myotubularin related protein 7 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
101723145  Mtmr6; myotubularin related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
101697627  Mtmr8; myotubularin related protein 8 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
101724817  Mtmr14; myotubularin related protein 14 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
101707981  Pi4ka; phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
101700192  Pi4kb; phosphatidylinositol 4-kinase beta [KO:K19801] [EC:2.7.1.67]
101701668  Pi4k2a; phosphatidylinositol 4-kinase type 2 alpha [KO:K13711] [EC:2.7.1.67]
101700160  Pi4k2b; phosphatidylinositol 4-kinase type 2 beta [KO:K13711] [EC:2.7.1.67]
101699134  Sacm1l; SAC1 suppressor of actin mutations 1-like (yeast) [KO:K21797] [EC:3.1.3.-]
101708953  Inpp5f; inositol polyphosphate-5-phosphatase F [KO:K21798] [EC:3.1.3.-]
101726083  Pip5k1b; phosphatidylinositol-4-phosphate 5-kinase type 1 beta [KO:K00889] [EC:2.7.1.68]
101703623  Pip5k1a; phosphatidylinositol-4-phosphate 5-kinase type 1 alpha [KO:K00889] [EC:2.7.1.68]
101700633  Pip5k1c; phosphatidylinositol-4-phosphate 5-kinase type 1 gamma [KO:K00889] [EC:2.7.1.68]
101716607  Pip5kl1; phosphatidylinositol-4-phosphate 5-kinase like 1 [KO:K13712] [EC:2.7.1.68]
101704216  Inpp5b; inositol polyphosphate-5-phosphatase B [KO:K01099] [EC:3.1.3.36]
101722262  Ocrl; OCRL, inositol polyphosphate-5-phosphatase [KO:K01099] [EC:3.1.3.36]
101701719  Inpp5e; inositol polyphosphate-5-phosphatase E [KO:K20278] [EC:3.1.3.36]
101700219  Synj2; synaptojanin 2 [KO:K20279] [EC:3.1.3.36]
101718278  Synj1; synaptojanin 1 [KO:K20279] [EC:3.1.3.36]
101725860  Plcb1; phospholipase C beta 1 [KO:K05858] [EC:3.1.4.11]
101696454  Plcb4; phospholipase C beta 4 [KO:K05858] [EC:3.1.4.11]
101697744  Plcb3; phospholipase C beta 3 [KO:K05858] [EC:3.1.4.11]
101708380  Plcb2; phospholipase C beta 2 [KO:K05858] [EC:3.1.4.11]
101715010  Plcd1; phospholipase C delta 1 [KO:K05857] [EC:3.1.4.11]
101704621  Plcd3; phospholipase C delta 3 [KO:K05857] [EC:3.1.4.11]
101704999  Plcd4; phospholipase C delta 4 [KO:K05857] [EC:3.1.4.11]
101706315  Plce1; phospholipase C epsilon 1 [KO:K05860] [EC:3.1.4.11]
101705192  Plcg1; phospholipase C gamma 1 [KO:K01116] [EC:3.1.4.11]
101715321  Plcg2; phospholipase C gamma 2 [KO:K05859] [EC:3.1.4.11]
101709944  Plcz1; phospholipase C zeta 1 [KO:K05861] [EC:3.1.4.11]
101717211  Plch1; phospholipase C eta 1 [KO:K19006] [EC:3.1.4.11]
101725366  Plch2; phospholipase C eta 2 [KO:K19006] [EC:3.1.4.11]
101703054  Itpkc; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
101698565  Itpka; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
101702375  Itpkb; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
101711589  Minpp1; multiple inositol-polyphosphate phosphatase 1 [KO:K03103] [EC:3.1.3.62 3.1.3.80]
101704617  Inpp5a; inositol polyphosphate-5-phosphatase A [KO:K01106] [EC:3.1.3.56]
101719531  Inpp5k; inositol polyphosphate-5-phosphatase K [KO:K24222] [EC:3.1.3.56]
101726724  Inpp5j; inositol polyphosphate-5-phosphatase J [KO:K24222] [EC:3.1.3.56]
101724306  Inpp1; inositol polyphosphate-1-phosphatase [KO:K01107] [EC:3.1.3.57]
101704416  Impa1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
101719152  Impa2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
101700462  Itpk1; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
101700113  Ipmk; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
101698360  Ippk; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
101718534  Inpp4a; inositol polyphosphate-4-phosphatase type I A [KO:K01109] [EC:3.1.3.66]
101719238  Inpp4b; inositol polyphosphate-4-phosphatase type II B [KO:K01109] [EC:3.1.3.66]
101723851  Isyna1; inositol-3-phosphate synthase 1 [KO:K01858] [EC:5.5.1.4]
101711934  Pik3ca; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [KO:K00922] [EC:2.7.1.153]
101715249  Pik3cb; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [KO:K00922] [EC:2.7.1.153]
101712941  Pik3cd; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [KO:K00922] [EC:2.7.1.153]
101707055  Pik3cg; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [KO:K21289] [EC:2.7.1.153]
101714930  Pten; phosphatase and tensin homolog [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
101711777  Inpp5d; inositol polyphosphate-5-phosphatase D [KO:K03084] [EC:3.1.3.86]
101698814  Inppl1; inositol polyphosphate phosphatase like 1 [KO:K15909] [EC:3.1.3.86]
101709126  Pik3c2g; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma [KO:K00923] [EC:2.7.1.154]
101702206  Pik3c2a; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha [KO:K00923] [EC:2.7.1.154]
101721434  Pik3c2b; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta [KO:K00923] [EC:2.7.1.154]
101705294  Pikfyve; phosphoinositide kinase, FYVE-type zinc finger containing [KO:K00921] [EC:2.7.1.150]
101713458  Fig4; FIG4 phosphoinositide 5-phosphatase [KO:K22913] [EC:3.1.3.-]
101719792  Pip4k2b; phosphatidylinositol-5-phosphate 4-kinase type 2 beta [KO:K00920] [EC:2.7.1.149]
101705091  Pip4k2a; phosphatidylinositol-5-phosphate 4-kinase type 2 alpha [KO:K00920] [EC:2.7.1.149]
101708848  Pip4k2c; phosphatidylinositol-5-phosphate 4-kinase type 2 gamma [KO:K00920] [EC:2.7.1.149]
101714318  Cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
101700386  Miox; myo-inositol oxygenase [KO:K00469] [EC:1.13.99.1]
101705709  Aldh6a1; aldehyde dehydrogenase 6 family member A1 [KO:K00140] [EC:1.2.1.18 1.2.1.27]
101720995  Tpi1; triosephosphate isomerase 1 [KO:K01803] [EC:5.3.1.1]
Compound
C00024  Acetyl-CoA
C00092  D-Glucose 6-phosphate
C00111  Glycerone phosphate
C00118  D-Glyceraldehyde 3-phosphate
C00137  myo-Inositol
C00191  D-Glucuronate
C00222  3-Oxopropanoate
C00558  D-Tagaturonate
C00641  1,2-Diacyl-sn-glycerol
C00691  2,4,6/3,5-Pentahydroxycyclohexanone
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C03659  D-Bornesitol
C03660  L-Bornesitol
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04287  3D-3,5/4-Trihydroxycyclohexane-1,2-dione
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04520  1D-myo-Inositol 3,4,5,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04563  D-myo-Inositol 1,2,4,5,6-pentakisphosphate
C04579  Inositol 1,2,3,5,6-pentakisphosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C06153  scyllo-Inositol
C06892  2-Deoxy-5-keto-D-gluconic acid
C06893  2-Deoxy-5-keto-D-gluconic acid 6-phosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C16737  5-Deoxy-D-glucuronate
C19794  CDP-1L-myo-inositol
C19799  Bis(1L-myo-inositol)-3,1'-phosphate 1-phosphate
C19891  1D-chiro-Inositol
C20251  1-Keto-D-chiro-inositol
C21643  3-Dehydro-scyllo-inosose
C21644  5-Dehydro-L-gluconate
Reference
PMID:14993306
  Authors
Yoshida K, Yamaguchi M, Ikeda H, Omae K, Tsurusaki K, Fujita Y
  Title
The fifth gene of the iol operon of Bacillus subtilis, iolE, encodes 2-keto-myo-inositol dehydratase.
  Journal
Microbiology 150:571-80 (2004)
DOI:10.1099/mic.0.26768-0
Reference
PMID:18310071
  Authors
Yoshida K, Yamaguchi M, Morinaga T, Kinehara M, Ikeuchi M, Ashida H, Fujita Y.
  Title
myo-Inositol catabolism in Bacillus subtilis.
  Journal
J Biol Chem 283:10415-24 (2008)
DOI:10.1074/jbc.M708043200
Related
pathway
hgl00010  Glycolysis / Gluconeogenesis
hgl00020  Citrate cycle (TCA cycle)
hgl00040  Pentose and glucuronate interconversions
hgl00564  Glycerophospholipid metabolism
KO pathway
ko00562   
LinkDB

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