KEGG   Homo sapiens (human): 3728
Entry
3728              CDS       T01001                                 
Symbol
JUP, CTNNG, DP3, DPIII, PDGB, PG, PKGB
Name
(RefSeq) junction plakoglobin
  KO
K10056  junction plakoglobin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04382  Cornified envelope formation
hsa04820  Cytoskeleton in muscle cells
hsa05200  Pathways in cancer
hsa05202  Transcriptional misregulation in cancer
hsa05221  Acute myeloid leukemia
hsa05226  Gastric cancer
hsa05412  Arrhythmogenic right ventricular cardiomyopathy
Network
nt06240  Transcription (cancer)
nt06275  Acute myeloid leukemia
nt06539  Cytoskeleton in muscle cells
nt06545  Cornified envelope formation
  Element
N00108  AML1-ETO fusion to transcriptional activtion
N00109  PML-RARA fusion to transcriptional activtion
N00110  PLZF-RARA fusion to transcriptional activtion
N01758  Desmosome - Vimentin filaments
N01922  Localization of envoplakin and periplakin to the plasma membrane (PM)
Disease
H00293  Arrhythmogenic right ventricular cardiomyopathy
H00669  Naxos disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    3728 (JUP)
 09150 Organismal Systems
  09158 Development and regeneration
   04382 Cornified envelope formation
    3728 (JUP)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    3728 (JUP)
   05202 Transcriptional misregulation in cancer
    3728 (JUP)
  09162 Cancer: specific types
   05226 Gastric cancer
    3728 (JUP)
   05221 Acute myeloid leukemia
    3728 (JUP)
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    3728 (JUP)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    3728 (JUP)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   3728 (JUP)
SSDB
Motif
Pfam: Arm ARM_ARMC5 HEAT V-ATPase_H_N Cnd1 HEAT_2 ARMC9_ARM Adaptin_N ELMO_ARM Atx10homo_assoc Arm_2 HEAT_EF3_N
Other DBs
NCBI-GeneID: 3728
NCBI-ProteinID: NP_002221
OMIM: 173325
HGNC: 6207
Ensembl: ENSG00000173801
UniProt: P14923 A0A0S2Z487
Structure
LinkDB
Position
17:complement(41754609..41786711)
AA seq 745 aa
MEVMNLMEQPIKVTEWQQTYTYDSGIHSGANTCVPSVSSKGIMEEDEACGRQYTLKKTTT
YTQGVPPSQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQATNLQRLAEPS
QLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALM
GSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVE
SVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQ
ESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKH
LTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTC
NNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNY
GIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQR
HVAAGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENI
QRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDKNPDY
RKRVSVELTNSLFKHDPAAWEAAQSMIPINEPYGDDMDATYRPMYSSDVPLDPLEMHMDM
DGDYPIDTYSDGLRPPYPTADHMLA
NT seq 2238 nt   +upstreamnt  +downstreamnt
atggaggtgatgaacctgatggagcagcctatcaaggtgactgagtggcagcagacatac
acctacgactcgggtatccactcgggcgccaacacctgcgtgccctccgtcagcagcaag
ggcatcatggaggaggatgaggcctgcgggcgccagtacacgctcaagaaaaccaccact
tacacccagggggtgccccccagccaaggtgatctggagtaccagatgtccacaacagcc
agggccaaacgggtgcgggaggccatgtgccctggtgtgtcaggcgaggacagctcgctt
ctgctggccacccaggtggaggggcaggccaccaacctgcagcgactggccgagccgtcc
cagctgctcaagtcggccattgtgcatctcatcaactaccaggacgatgccgagctggcc
actcgcgccctgcccgagctcaccaaactgctcaacgacgaggacccggtggtggtgacc
aaggcggccatgattgtgaaccagctgtcgaagaaggaggcgtcgcggcgggccctgatg
ggctcgccccagctggtggccgctgtcgtgcgtaccatgcagaataccagcgacctggac
acagcccgctgcaccaccagcatcctgcacaacctctcccaccaccgggaggggctgctc
gccatcttcaagtcgggtggcatccctgctctggtccgcatgctcagctcccctgtggag
tcggtcctgttctatgccatcaccacgctgcacaacctgctcctgtaccaggagggcgcc
aagatggccgtgcgcctggccgacgggctgcaaaagatggtgcccctgctcaacaagaac
aaccccaagttcctggccatcaccaccgactgcctgcagctcctggcctacggcaaccag
gagagcaagctgatcatcctggccaatggtgggccccaggccctcgtgcagatcatgcgt
aactacagttatgaaaagctgctctggaccaccagtcgtgtgctcaaggtgctatccgtg
tgtcccagcaataagcctgccattgtggaggctggtgggatgcaggccctgggcaagcac
ctgaccagcaacagcccccgcctggtgcagaactgcctgtggaccctgcgcaacctctca
gatgtggccaccaagcaggagggcctggagagtgtgctgaagattctggtgaatcagctg
agtgtggatgacgtcaacgtcctcacctgtgccacgggcacactctccaacctgacatgc
aacaacagcaagaacaagacgctggtgacacagaacagcggtgtggaggctctcatccat
gccatcctgcgtgctggtgacaaggacgacatcacggagcctgccgtctgcgctctgcgc
cacctcactagccgccaccctgaggccgagatggcccagaactctgtgcgtctcaactat
ggcatcccagccatcgtgaagctgctcaaccagcccaaccagtggccactggtcaaggca
accatcggcttgatcaggaatctggccctgtgcccagccaaccatgccccgctgcaggag
gcagcggtcatcccccgcctcgtccaactgctggtgaaggcccaccaggatgcccagcgc
cacgtagctgcaggcacacagcagccctacacggatggtgtgaggatggaggagattgtg
gagggctgcaccggagcactgcacatcctcgcccgggaccccatgaaccgcatggagatc
ttccggctcaacaccattcccctgtttgtgcagctcctgtactcgtcggtggagaacatc
cagcgcgtggctgccggggtgctgtgtgagctggcccaggacaaggaggcggccgacgcc
attgatgcagagggggcctcggccccactcatggagttgctgcactcccgcaacgagggc
actgccacctacgctgctgccgtcctgttccgcatctccgaggacaagaacccagactac
cggaagcgcgtgtccgtggagctcaccaactccctcttcaagcatgacccggctgcctgg
gaggctgcccagagcatgattcccatcaatgagccctatggagatgacatggatgccacc
taccgccccatgtactccagcgatgtgccccttgacccgctggagatgcacatggacatg
gatggagactaccccatcgacacctacagcgacggcctcaggcccccgtaccccactgca
gaccacatgctggcctag

KEGG   Homo sapiens (human): 8900
Entry
8900              CDS       T01001                                 
Symbol
CCNA1, CT146
Name
(RefSeq) cyclin A1
  KO
K06627  cyclin-A
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
hsa04152  AMPK signaling pathway
hsa04218  Cellular senescence
hsa04914  Progesterone-mediated oocyte maturation
hsa05161  Hepatitis B
hsa05165  Human papillomavirus infection
hsa05166  Human T-cell leukemia virus 1 infection
hsa05169  Epstein-Barr virus infection
hsa05200  Pathways in cancer
hsa05202  Transcriptional misregulation in cancer
hsa05203  Viral carcinogenesis
hsa05221  Acute myeloid leukemia
Network
nt06165  Epstein-Barr virus (EBV)
nt06166  Human papillomavirus (HPV)
nt06230  Cell cycle (cancer)
nt06240  Transcription (cancer)
nt06261  Gastric cancer
nt06267  Small cell lung cancer
nt06272  Prostate cancer
nt06275  Acute myeloid leukemia
nt06509  DNA replication
  Element
N00091  p27-Cell cycle G1/S
N00109  PML-RARA fusion to transcriptional activtion
N00110  PLZF-RARA fusion to transcriptional activtion
N00264  EBV EBNA3C to p27-Cell cycle G1/S
N00482  EBV EBNA3C to p27-Cell cycle G1/S
N01468  DNA replication licensing
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    8900 (CCNA1)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    8900 (CCNA1)
   04218 Cellular senescence
    8900 (CCNA1)
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    8900 (CCNA1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    8900 (CCNA1)
   05202 Transcriptional misregulation in cancer
    8900 (CCNA1)
   05203 Viral carcinogenesis
    8900 (CCNA1)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    8900 (CCNA1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    8900 (CCNA1)
   05161 Hepatitis B
    8900 (CCNA1)
   05169 Epstein-Barr virus infection
    8900 (CCNA1)
   05165 Human papillomavirus infection
    8900 (CCNA1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    8900 (CCNA1)
   03036 Chromosome and associated proteins [BR:hsa03036]
    8900 (CCNA1)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Initiation Factors
   CDK (cyclin dependent kinase)
    8900 (CCNA1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Cyclins
    8900 (CCNA1)
SSDB
Motif
Pfam: Cyclin_N Cyclin_C Cyclin_N2
Other DBs
NCBI-GeneID: 8900
NCBI-ProteinID: NP_001104515
OMIM: 604036
HGNC: 1577
Ensembl: ENSG00000133101
UniProt: P78396 A0A140VJG0
LinkDB
Position
13:36431517..36442870
AA seq 421 aa
MHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRI
RCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEV
DTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEI
RHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRG
KLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTT
NQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFW
PETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL
Q
NT seq 1266 nt   +upstreamnt  +downstreamnt
atgcactgcagcaaccccaagagtggagttgtgctggctacagtggcccgaggtcccgat
gcttgtcagatactcaccagagccccgctgggccaggatcccccgcagaggacagtgcta
gggctgctaactgcaaatgggcagtacaggaggacctgtggccaggggatcacaagaatc
aggtgttattctggatcagaaaatgccttccctccagctggaaagaaagcactccctgac
tgtggggtccaagagccccccaagcaagggtttgacatctacatggatgaactagagcag
ggggacagagacagctgctcggtcagagaggggatggcatttgaggatgtgtatgaagta
gacaccggcacactcaagtcagacctgcacttcctgctggatttcaacacagtttcccct
atgctggtagattcatctctcctctcccagtctgaagatatatccagtcttggcacagat
gtgataaatgtgactgaatatgctgaagaaatttatcagtaccttagggaagctgaaata
aggcacagacccaaagcacactacatgaagaagcagccagacatcacggaaggcatgcgc
acgattctggtggactggctggtggaggttggggaagaatataaacttcgagcagagacc
ctgtatctggctgtcaacttcctggacaggttcctttcatgtatgtctgttctgagaggg
aaactgcagctcgtaggaacagcagctatgcttttggcttcgaaatatgaagagatatat
cctcctgaagtagacgagtttgtctatatcaccgatgatacatacacaaaacgacaactg
ttaaaaatggaacacttgcttctgaaagttctagcttttgatctgacagtaccaaccacc
aaccagtttctccttcagtacttgaggcgacaaggagtgtgcgtcaggactgagaacctg
gctaagtacgtagcagagctgagtctacttgaagcagatccattcttgaaatatcttcct
tcactgatagctgcagcagctttttgcctggcaaactatactgtgaacaagcacttttgg
ccagaaacccttgctgcatttacagggtattcattaagtgaaattgtgccttgcctgagt
gagcttcataaagcgtaccttgatataccccatcgacctcagcaagcaattagggagaag
tacaaggcttcaaagtacctgtgtgtgtccctcatggagccacctgcagttcttcttcta
caataa

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