Homo sapiens (human): 4868
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Entry
4868 CDS
T01001
Symbol
NPHS1, CNF, NPHN, nephrin
Name
(RefSeq) NPHS1 adhesion molecule, nephrin
KO
K24496
nephrin
Organism
hsa
Homo sapiens (human)
Pathway
hsa04517
IgSF CAM signaling
Network
nt06546
IgSF CAM signaling
Element
N01943
SLIT-ROBO signaling in podocyte
N01961
NPHS1/NEPH interactions
Disease
H01657
Nephrotic syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
4868 (NPHS1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04990 Domain-containing proteins not elsewhere classified [BR:
hsa04990
]
4868 (NPHS1)
Domain-containing proteins not elsewhere classified [BR:
hsa04990
]
Fibronectin (FN) domain-containing proteins
Fibronectin type III domain-containing proteins
4868 (NPHS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
C2-set_2
Ig_3
I-set
Ig_2
ig
V-set
fn3
C2-set_3
Ig_DSCAM-DSCAML_C
DUF4643
Motif
Other DBs
NCBI-GeneID:
4868
NCBI-ProteinID:
NP_004637
OMIM:
602716
HGNC:
7908
Ensembl:
ENSG00000161270
UniProt:
O60500
Structure
PDB
PDBj
LinkDB
All DBs
Position
19:complement(35825372..35852504)
Genome browser
AA seq
1241 aa
AA seq
DB search
MALGTTLRASLLLLGLLTEGLAQLAIPASVPRGFWALPENLTVVEGASVELRCGVSTPGS
AVQWAKDGLLLGPDPRIPGFPRYRLEGDPARGEFHLHIEACDLSDDAEYECQVGRSEMGP
ELVSPRVILSILVPPKLLLLTPEAGTMVTWVAGQEYVVNCVSGDAKPAPDITILLSGQTI
SDISANVNEGSQQKLFTVEATARVTPRSSDNRQLLVCEASSPALEAPIKASFTVNVLFPP
GPPVIEWPGLDEGHVRAGQSLELPCVARGGNPLATLQWLKNGQPVSTAWGTEHTQAVARS
VLVMTVRPEDHGAQLSCEAHNSVSAGTQEHGITLQVTFPPSAIIILGSASQTENKNVTLS
CVSKSSRPRVLLRWWLGWRQLLPMEETVMDGLHGGHISMSNLTFLARREDNGLTLTCEAF
SEAFTKETFKKSLILNVKYPAQKLWIEGPPEGQKLRAGTRVRLVCLAIGGNPEPSLMWYK
DSRTVTESRLPQESRRVHLGSVEKSGSTFSRELVLVTGPSDNQAKFTCKAGQLSASTQLA
VQFPPTNVTILANASALRPGDALNLTCVSVSSNPPVNLSWDKEGERLEGVAAPPRRAPFK
GSAAARSVLLQVSSRDHGQRVTCRAHSAELRETVSSFYRLNVLYRPEFLGEQVLVVTAVE
QGEALLPVSVSANPAPEAFNWTFRGYRLSPAGGPRHRILSSGALHLWNVTRADDGLYQLH
CQNSEGTAEARLRLDVHYAPTIRALQDPTEVNVGGSVDIVCTVDANPILPGMFNWERLGE
DEEDQSLDDMEKISRGPTGRLRIHHAKLAQAGAYQCIVDNGVAPPARRLLRLVVRFAPQV
EHPTPLTKVAAAGDSTSSATLHCRARGVPNIVFTWTKNGVPLDLQDPRYTEHTYHQGGVH
SSLLTIANVSAAQDYALFTCTATNALGSDQTNIQLVSISRPDPPSGLKVVSLTPHSVGLE
WKPGFDGGLPQRFCIRYEALGTPGFHYVDVVPPQATTFTLTGLQPSTRYRVWLLASNALG
DSGLADKGTQLPITTPGLHQPSGEPEDQLPTEPPSGPSGLPLLPVLFALGGLLLLSNASC
VGGVLWQRRLRRLAEGISEKTEAGSEEDRVRNEYEESQWTGERDTQSSTVSTTEAEPYYR
SLRDFSPQLPPTQEEVSYSRGFTGEDEDMAFPGHLYDEVERTYPPSGAWGPLYDEVQMGP
WDLHWPEDTYQDPRGIYDQVAGDLDTLEPDSLPFELRGHLV
NT seq
3726 nt
NT seq
+upstream
nt +downstream
nt
atggccctggggacgacgctcagggcttctctcctgctcctggggctgctgactgaaggc
ctggcgcagttggcgattcctgcctccgttccccggggcttctgggccctgcctgaaaac
ctgacggtggtggagggggcctcagtggagctgcgttgtggggtcagcacccctggcagt
gcggtgcaatgggccaaagatgggctgctcctgggccccgaccccaggatcccaggcttc
ccgaggtaccgcctggaaggggaccctgctagaggtgaattccacctgcacatcgaggcc
tgtgacctcagcgatgacgcggagtatgagtgccaggtcggccgctctgagatggggccc
gagctcgtgtctcccagagtgatcctctccatcctggttcctcccaagctgctcctgctg
accccagaggcaggcaccatggtcacctgggtagctgggcaggagtacgtggtcaactgt
gtgtctggggacgcgaagccagcacctgacatcaccattctcctgagtggacagacaata
tctgacatctctgcaaacgtgaacgagggctcccagcagaaactcttcactgtggaggcc
acagccagggtgacaccccggagctcagataataggcagttgctggtctgtgaggcgtct
agcccagcactggaggcccccatcaaggcctcattcaccgtgaatgttctgttccctcca
ggaccccctgtcatcgagtggccaggcctggatgaggggcacgtgcgggcaggacagagc
ttggagctgccgtgcgtggcccgagggggtaatcccttagccacactgcagtggctgaag
aatggccagccggtgtccacagcgtggggcacagagcacacccaggcggtggcccgcagt
gtgctggtgatgaccgtgaggccagaagaccatggagcgcagctcagctgcgaggcccac
aacagcgtgtctgcagggacccaggagcacggcatcacactgcaggtcacctttccccct
agtgccattattatcttgggatctgcatcccagactgagaacaagaacgtgacactctcc
tgtgtcagcaagtccagtcgcccgcgggttctgctacgatggtggctgggctggcggcag
ctgctgcccatggaggagacagtcatggatggactgcatggcggtcacatctccatgtcc
aacctgacattcctggcgcggcgggaggacaacggtctgaccctcacatgtgaggccttc
agtgaagccttcaccaaggagaccttcaagaagtcgctcatcctgaacgtaaaatatccc
gcccagaaactgtggattgagggtcccccagagggccagaagctccgggctgggacccgg
gtgaggctggtgtgtttggctatcgggggcaacccagagccctccctcatgtggtacaag
gactcgcgcaccgtgaccgagtcgcggctgccgcaggagtcgcggcgcgtgcatctcggc
agcgtggagaaatctgggagcaccttctcccgagagctggtgctggtcacagggccgtcg
gacaaccaggccaagttcacgtgcaaggctggacagctcagcgcgtccacgcagctggcg
gtgcagtttcccccaactaacgtgacgatcctggccaacgcatccgcactgcgcccggga
gacgccttaaacttgacatgcgtcagcgtcagcagcaatccgccggtcaacttgtcctgg
gacaaggaaggggagaggctggagggcgtggccgccccaccccggagagccccattcaaa
ggctccgccgccgccaggagcgtccttctgcaagtgtcatcccgcgatcatggccagcgc
gtgacctgccgcgcccacagcgccgagctccgcgaaaccgtgagctccttctatcgcctc
aacgtactgtaccgtccagagttcctgggggagcaggtgctggtggtgaccgcggtggag
cagggcgaggcgttgctgcccgtgtccgtgtccgctaaccccgcccccgaggccttcaac
tggaccttccgcggctatcgcctcagtccagcgggcggcccccggcatcgcatcctgtcc
agcggggctctgcatctgtggaatgtgacccgcgcggacgacggcctctatcagctgcac
tgccagaactctgagggcaccgcggaagcgcggctgcggctggacgtgcactatgctccc
accatccgtgccctccaggaccccactgaggtgaacgtcgggggttctgtggacatagtc
tgcactgtcgatgccaatcccatcctcccgggcatgttcaactgggagagactgggagaa
gatgaggaggaccagagcctggatgacatggagaagatatccaggggaccaacggggcgc
ctgcggattcaccatgccaaactggcccaggctggcgcttaccagtgcattgtggacaat
ggggtggcgcctccagcacgacggctgctccgtcttgttgtcagatttgccccccaggtg
gagcaccccactcccctaactaaggtggctgcagctggagacagcaccagttctgccacc
ctccactgccgtgcccgaggtgtccccaacatcgttttcacttggacaaaaaacggggtc
cctctggatctccaagatcccaggtacacggagcacacataccaccagggtggtgtccac
agcagcctcctgaccattgccaacgtgtctgccgcccaggattacgccctcttcacatgt
acagccaccaacgcccttggctcggaccaaaccaacattcaacttgtcagcatcagccgc
cctgaccctccatcaggattaaaggttgtgagtctgaccccacactccgtggggctggag
tggaagcctggctttgatgggggcctgccacagaggttctgcatcaggtatgaggccctg
gggactccagggttccactatgtggatgtcgtaccaccccaggccaccaccttcacgctg
actggtctacagccttctacaagatacagggtctggctgctggccagtaatgccttgggg
gacagtggactggctgacaaagggacccagcttcccatcactaccccaggtctccaccag
ccttctggagaacctgaagaccagctgcccacagagccaccttcaggaccctcggggctg
cccctgctgcctgtgctgttcgctcttggggggcttctgctcctctccaatgcctcctgt
gtcgggggggtcctctggcagcggagactcaggcgtcttgctgagggcatctcagagaag
acagaggcagggtcggaagaggaccgagtcaggaacgaatatgaggagagccagtggaca
ggagagcgggacactcagagctccacggtcagcacaacagaggcagagccgtattaccgc
tccctgagggacttcagcccccagctgcccccgacgcaggaggaggtgtcttattcccga
ggtttcacaggtgaagatgaggatatggccttccctgggcacttgtatgatgaggtagaa
agaacgtaccccccgtctggagcctggggacccctctacgatgaagtgcagatgggaccc
tgggacctccactggcctgaagacacatatcaggatccaagaggaatctatgaccaggtg
gccggagacttggacactctggaacccgattctctgcccttcgagctgaggggacatctg
gtgtaa
Homo sapiens (human): 4690
Help
Entry
4690 CDS
T01001
Symbol
NCK1, NCK, NCKalpha, nck-1
Name
(RefSeq) NCK adaptor protein 1
KO
K07365
NCK adaptor protein 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04012
ErbB signaling pathway
hsa04360
Axon guidance
hsa04517
IgSF CAM signaling
hsa04660
T cell receptor signaling pathway
hsa05130
Pathogenic Escherichia coli infection
Network
nt06180
Pathogenic Escherichia coli
nt06182
Shigella
nt06546
IgSF CAM signaling
Element
N01078
EGF-EGFR-Actin signaling pathway
N01092
Escherichia Eae/Tir to Actin signaling pathway
N01093
Escherichia EspJ/Tir to Actin signaling pathway
N01940
Netrin-1 attractive signaling
N01943
SLIT-ROBO signaling in podocyte
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
4690 (NCK1)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
4690 (NCK1)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
4690 (NCK1)
09158 Development and regeneration
04360 Axon guidance
4690 (NCK1)
09160 Human Diseases
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
4690 (NCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SH3_1
SH3_9
SH3_2
SH2
SH3_3
SH3_10
hSH3
DUF7063
SH2_2
SH2_1
Motif
Other DBs
NCBI-GeneID:
4690
NCBI-ProteinID:
NP_001278928
OMIM:
600508
HGNC:
7664
Ensembl:
ENSG00000158092
UniProt:
P16333
A0A0S2Z4Y3
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:136862208..136951606
Genome browser
AA seq
377 aa
AA seq
DB search
MAEEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKN
SARKASIVKNLKDTLGIGKVKRKPSVPDSASPADDSFVDPGERLYDLNMPAYVKFNYMAE
REDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWFPSNYVTEEGDSPLGDHVGSLSEKLA
AVVNNLNTGQVLHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVG
LVPKNYVTVMQNNPLTSGLEPSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERG
HEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAP
IFTSEQGEKLYLVKHLS
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atggcagaagaagtggtggtagtagccaaatttgattatgtggcccaacaagaacaagag
ttggacatcaagaagaatgagagattatggcttctggatgattctaagtcctggtggcga
gttcgaaattccatgaataaaacaggttttgtgccttctaactatgtggaaaggaaaaac
agtgctcggaaagcatctattgtgaaaaacctaaaggataccttaggcattggaaaagtg
aaaagaaaacctagtgtgccagattctgcatctcctgctgatgatagttttgttgaccca
ggggaacgtctctatgacctcaacatgcccgcttatgtgaaatttaactacatggctgag
agagaggatgaattatcattgataaaggggacaaaggtgatcgtcatggagaaatgcagt
gatgggtggtggcgtggtagctacaatggacaagttggatggttcccttcaaactatgta
actgaagaaggtgacagtcctttgggtgaccatgtgggttctctgtcagagaaattagca
gcagtcgtcaataacctaaatactgggcaagtgttgcatgtggtacaggctctttaccca
ttcagctcatctaatgatgaagaacttaatttcgagaaaggagatgtaatggatgttatt
gaaaaacctgaaaatgacccagagtggtggaaatgcaggaagatcaatggtatggttggt
ctagtaccaaaaaactatgttaccgttatgcagaataatccattaacttcaggtttggaa
ccatcacctccacagtgtgattacattaggccttcactcactggaaagtttgctggcaat
ccttggtattatggcaaagtcaccaggcatcaagcagaaatggcattaaatgaaagagga
catgaaggggatttcctcattcgtgatagtgaatcttcgccaaatgatttctcagtatca
ctaaaagcacaagggaaaaacaagcattttaaagtccaactaaaagagactgtctactgc
attgggcagcgtaaattcagcaccatggaagaacttgtagaacattacaaaaaggcacca
atttttacaagtgaacaaggagaaaaattatatcttgtcaagcatttatcatga
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integrated database retrieval system
