Homo sapiens (human): 5732 Help Entry 5732              CDS       T01001                                  Symbol PTGER2, EP2 Name (RefSeq) prostaglandin E receptor 2   KO K04259   prostaglandin E receptor 2 Organism hsa  Homo sapiens (human) Pathway hsa04024   cAMP signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04148   Efferocytosis hsa04750   Inflammatory mediator regulation of TRP channels hsa04924   Renin secretion hsa05163   Human cytomegalovirus infection hsa05200   Pathways in cancer Network nt06535  Efferocytosis   Element N01773   PTGS2-PGE2-TGFB1 pathway Disease H01191   Asthma with nasal polyps and aspirin intolerance Drug target Arbaprostil:  D02975 Butaprost:  D03187 Dinoprostone (DG00448):  D00079<JP/US> D03269 Enprostil:  D01891 Evatanepag (DG01894):  D09613 D09614 Meteneprost:  D02726 Misoprostol:  D00419<JP/US> Omidenepag (DG02831):  D10965 D10966<JP/US> Rioprostil:  D05732 Sulprostone:  D02725 Taprenepag (DG01895):  D09968 D09969 Trimoprostil:  D06240 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04024 cAMP signaling pathway     5732 (PTGER2)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     5732 (PTGER2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     5732 (PTGER2)  09150 Organismal Systems   09152 Endocrine system    04924 Renin secretion     5732 (PTGER2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     5732 (PTGER2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     5732 (PTGER2)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     5732 (PTGER2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     5732 (PTGER2) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Lipid    Prostaglandin     5732 (PTGER2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srx 7TM_GPCR_Srsx Srg Motif Other DBs NCBI-GeneID:  5732 NCBI-ProteinID:  NP_000947 OMIM:  176804 HGNC:  9594 Ensembl:  ENSG00000125384 Pharos:  P43116(Tclin) UniProt:  P43116 Structure PDBPDBj LinkDB All DBs Position 14:52314312..52328598 Genome browser AA seq 358 aa AA seqDB search MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL NT seq 1077 nt NT seq  +upstreamnt  +downstreamnt atgggcaatgcctccaatgactcccagtctgaggactgcgagacgcgacagtggcttccc ccaggcgaaagcccagccatcagctccgtcatgttctcggccggggtgctggggaacctc atagcactggcgctgctggcgcgccgctggcggggggacgtggggtgcagcgccggccgc aggagctccctctccttgttccacgtgctggtgaccgagctggtgttcaccgacctgctc gggacctgcctcatcagcccagtggtactggcttcgtacgcgcggaaccagaccctggtg gcactggcgcccgagagccgcgcgtgcacctacttcgctttcgccatgaccttcttcagc ctggccacgatgctcatgctcttcgccatggccctggagcgctacctctcgatcgggcac ccctacttctaccagcgccgcgtctcgcgctccgggggcctggccgtgctgcctgtcatc tatgcagtctccctgctcttctgctcgctgccgctgctggactatgggcagtacgtccag tactgccccgggacctggtgcttcatccggcacgggcggaccgcttacctgcagctgtac gccaccctgctgctgcttctcattgtctcggtgctcgcctgcaacttcagtgtcattctc aacctcatccgcatgcaccgccgaagccggagaagccgctgcggaccttccctgggcagt ggccggggcggccccggggcccgcaggagaggggaaagggtgtccatggcggaggagacg gaccacctcattctcctggctatcatgaccatcaccttcgccgtctgctccttgcctttc acgatttttgcatatatgaatgaaacctcttcccgaaaggaaaaatgggacctccaagct cttaggtttttatcaattaattcaataattgacccttgggtctttgccatccttaggcct cctgttctgagactaatgcgttcagtcctctgttgtcggatttcattaagaacacaagat gcaacacaaacttcctgttctacacagtcagatgccagtaaacaggctgacctttga

Homo sapiens (human): 5734 Help Entry 5734              CDS       T01001                                  Symbol PTGER4, EP4, EP4R Name (RefSeq) prostaglandin E receptor 4   KO K04261   prostaglandin E receptor 4 Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04148   Efferocytosis hsa04750   Inflammatory mediator regulation of TRP channels hsa04924   Renin secretion hsa05163   Human cytomegalovirus infection hsa05165   Human papillomavirus infection hsa05200   Pathways in cancer Network nt06535  Efferocytosis   Element N01773   PTGS2-PGE2-TGFB1 pathway Drug target Grapiprant:  D10638 Misoprostol:  D00419<JP/US> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     5734 (PTGER4)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     5734 (PTGER4)  09150 Organismal Systems   09152 Endocrine system    04924 Renin secretion     5734 (PTGER4)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     5734 (PTGER4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     5734 (PTGER4)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     5734 (PTGER4)    05165 Human papillomavirus infection     5734 (PTGER4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     5734 (PTGER4) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Lipid    Prostaglandin     5734 (PTGER4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srx 7TM_GPCR_Srsx NdhL Motif Other DBs NCBI-GeneID:  5734 NCBI-ProteinID:  NP_000949 OMIM:  601586 HGNC:  9596 Ensembl:  ENSG00000171522 Pharos:  P35408(Tclin) UniProt:  P35408 A0PJF5 Structure PDBPDBj LinkDB All DBs Position 5:40679915..40746800 Genome browser AA seq 488 aa AA seqDB search MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP SLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSG QHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPG MGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSET LNLSEKCI NT seq 1467 nt NT seq  +upstreamnt  +downstreamnt atgtccactcccggggtcaattcgtccgcctccttgagccccgaccggctgaacagccca gtgaccatcccggcggtgatgttcatcttcggggtggtgggcaacctggtggccatcgtg gtgctgtgcaagtcgcgcaaggagcagaaggagacgaccttctacacgctggtatgtggg ctggctgtcaccgacctgttgggcactttgttggtgagcccggtgaccatcgccacgtac atgaagggccaatggcccgggggccagccgctgtgcgagtacagcaccttcattctgctc ttcttcagcctgtccggcctcagcatcatctgcgccatgagtgtcgagcgctacctggcc atcaaccatgcctatttctacagccactacgtggacaagcgattggcgggcctcacgctc tttgcagtctatgcgtccaacgtgctcttttgcgcgctgcccaacatgggtctcggtagc tcgcggctgcagtacccagacacctggtgcttcatcgactggaccaccaacgtgacggcg cacgccgcctactcctacatgtacgcgggcttcagctccttcctcattctcgccaccgtc ctctgcaacgtgcttgtgtgcggcgcgctgctccgcatgcaccgccagttcatgcgccgc acctcgctgggcaccgagcagcaccacgcggccgcggccgcctcggttgcctcccggggc caccccgctgcctccccagccttgccgcgcctcagcgactttcggcgccgccggagcttc cgccgcatcgcgggcgccgagatccagatggtcatcttactcattgccacctccctggtg gtgctcatctgctccatcccgctcgtggtgcgagtattcgtcaaccagttatatcagcca agtttggagcgagaagtcagtaaaaatccagatttgcaggccatccgaattgcttctgtg aaccccatcctagacccctggatatatatcctcctgagaaagacagtgctcagtaaagca atagagaagatcaaatgcctcttctgccgcattggcgggtcccgcagggagcgctccgga cagcactgctcagacagtcaaaggacatcttctgccatgtcaggccactctcgctccttc atctcccgggagctgaaggagatcagcagtacatctcagaccctcctgccagacctctca ctgccagacctcagtgaaaatggccttggaggcaggaatttgcttccaggtgtgcctggc atgggcctggcccaggaagacaccacctcactgaggactttgcgaatatcagagacctca gactcttcacagggtcaggactcagagagtgtcttactggtggatgaggctggtgggagc ggcagggctgggcctgcccctaaggggagctccctgcaagtcacatttcccagtgaaaca ctgaacttatcagaaaaatgtatataa

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