Homo sapiens (human): 6500
Help
Entry
6500 CDS
T01001
Symbol
SKP1, EMC19, OCP-II, OCP2, SKP1A, TCEB1L, p19A
Name
(RefSeq) S-phase kinase associated protein 1
KO
K03094
S-phase kinase-associated protein 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa03083
Polycomb repressive complex
hsa04110
Cell cycle
hsa04114
Oocyte meiosis
hsa04120
Ubiquitin mediated proteolysis
hsa04141
Protein processing in endoplasmic reticulum
hsa04310
Wnt signaling pathway
hsa04350
TGF-beta signaling pathway
hsa04710
Circadian rhythm
hsa05131
Shigellosis
hsa05132
Salmonella infection
hsa05170
Human immunodeficiency virus 1 infection
hsa05200
Pathways in cancer
Network
nt06165
Epstein-Barr virus (EBV)
nt06166
Human papillomavirus (HPV)
nt06181
Salmonella
nt06182
Shigella
nt06230
Cell cycle (cancer)
nt06261
Gastric cancer
nt06267
Small cell lung cancer
nt06272
Prostate cancer
nt06516
TNF signaling
nt06523
Epigenetic regulation by Polycomb complexes
Element
N00091
p27-Cell cycle G1/S
N00092
Amplified MYC to p27-cell cycle G1/S
N00942
Shigella OspG to TNF-NFKB signaling pathway
N01117
Salmonella GogB to TNF-NFKB signaling pathway
N01586
Activation of PRC2.2 by ubiquitination of H2AK119
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
6500 (SKP1)
04120 Ubiquitin mediated proteolysis
6500 (SKP1)
09126 Chromosome
03083 Polycomb repressive complex
6500 (SKP1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
6500 (SKP1)
04350 TGF-beta signaling pathway
6500 (SKP1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
6500 (SKP1)
04114 Oocyte meiosis
6500 (SKP1)
09150 Organismal Systems
09159 Environmental adaptation
04710 Circadian rhythm
6500 (SKP1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
6500 (SKP1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
6500 (SKP1)
09171 Infectious disease: bacterial
05132 Salmonella infection
6500 (SKP1)
05131 Shigellosis
6500 (SKP1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
6500 (SKP1)
04121 Ubiquitin system [BR:
hsa04121
]
6500 (SKP1)
03036 Chromosome and associated proteins [BR:
hsa03036
]
6500 (SKP1)
Membrane trafficking [BR:
hsa04131
]
Endosome - Lysosome transport
Acidification regulators
RAVE complex
6500 (SKP1)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin ligases (E3)
Multi subunit Ring-finger type E3
SCF complex
Adaptor protein
6500 (SKP1)
Cul7 complex
6500 (SKP1)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Histone modification proteins
Polycomb repressive complex (PRC) and associated proteins
Noncanonical PRC1 (PRC1.1)
6500 (SKP1)
Centromeric chromatin formation proteins
Kinetochore proteins
CBF3 complex
6500 (SKP1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Skp1
Skp1_POZ
Motif
Other DBs
NCBI-GeneID:
6500
NCBI-ProteinID:
NP_733779
OMIM:
601434
HGNC:
10899
Ensembl:
ENSG00000113558
UniProt:
P63208
Structure
PDB
LinkDB
All DBs
Position
5:complement(134148935..134176950)
Genome browser
AA seq
163 aa
AA seq
DB search
MPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQ
WCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTC
KTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK
NT seq
492 nt
NT seq
+upstream
nt +downstream
nt
atgccttcaattaagttgcagagttctgatggagagatatttgaagttgatgtggaaatt
gccaaacaatctgtgactattaagaccatgttggaagatttgggaatggatgatgaagga
gatgatgacccagttcctctaccaaatgtgaatgcagcaatattaaaaaaggtcattcag
tggtgcacccaccacaaggatgaccctcctcctcctgaagatgatgagaacaaagaaaag
cgaacagatgatatccctgtttgggaccaagaattcctgaaagttgaccaaggaacactt
tttgaactcattctggctgcaaactacttagacatcaaaggtttgcttgatgttacatgc
aagactgttgccaatatgatcaaggggaaaactcctgaggagattcgcaagaccttcaat
atcaaaaatgactttactgaagaggaggaagcccaggtacgcaaagagaaccagtggtgt
gaagagaagtga
Homo sapiens (human): 8454
Help
Entry
8454 CDS
T01001
Symbol
CUL1
Name
(RefSeq) cullin 1
KO
K03347
cullin 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04110
Cell cycle
hsa04114
Oocyte meiosis
hsa04120
Ubiquitin mediated proteolysis
hsa04141
Protein processing in endoplasmic reticulum
hsa04310
Wnt signaling pathway
hsa04340
Hedgehog signaling pathway
hsa04350
TGF-beta signaling pathway
hsa04710
Circadian rhythm
hsa05131
Shigellosis
hsa05170
Human immunodeficiency virus 1 infection
hsa05200
Pathways in cancer
Network
nt06165
Epstein-Barr virus (EBV)
nt06166
Human papillomavirus (HPV)
nt06182
Shigella
nt06230
Cell cycle (cancer)
nt06261
Gastric cancer
nt06267
Small cell lung cancer
nt06272
Prostate cancer
nt06516
TNF signaling
Element
N00091
p27-Cell cycle G1/S
N00092
Amplified MYC to p27-cell cycle G1/S
N00942
Shigella OspG to TNF-NFKB signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
8454 (CUL1)
04120 Ubiquitin mediated proteolysis
8454 (CUL1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
8454 (CUL1)
04340 Hedgehog signaling pathway
8454 (CUL1)
04350 TGF-beta signaling pathway
8454 (CUL1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
8454 (CUL1)
04114 Oocyte meiosis
8454 (CUL1)
09150 Organismal Systems
09159 Environmental adaptation
04710 Circadian rhythm
8454 (CUL1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
8454 (CUL1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
8454 (CUL1)
09171 Infectious disease: bacterial
05131 Shigellosis
8454 (CUL1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
8454 (CUL1)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin ligases (E3)
Multi subunit Ring-finger type E3
SCF complex
Cullin
8454 (CUL1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Cullin
Cullin_Nedd8
IntS11_C
Motif
Other DBs
NCBI-GeneID:
8454
NCBI-ProteinID:
NP_003583
OMIM:
603134
HGNC:
2551
Ensembl:
ENSG00000055130
UniProt:
Q13616
A0A090N7U0
B3KTW0
Structure
PDB
LinkDB
All DBs
Position
7:148697756..148801110
Genome browser
AA seq
776 aa
AA seq
DB search
MSSTRSQNPHGLKQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSN
QARGAGVPPSKSKKGQTPGGAQFVGLELYKRLKEFLKNYLTNLLKDGEDLMDESVLKFYT
QQWEDYRFSSKVLNGICAYLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLFRPLNKQVT
NAVLKLIEKERNGETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADT
ERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHL
EIFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCGEAAL
NDPKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPE
LLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSA
SDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNSEPLDLDFSIQVL
SSGSWPFQQSCTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYT
LQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDE
VELKPDTLIKLYLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMK
MRKVLKHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA
NT seq
2331 nt
NT seq
+upstream
nt +downstream
nt
atgtcgtcaacccggagccagaacccccacggcctgaagcagattggcctggaccagatc
tgggacgacctcagagccggcatccagcaggtgtacacacggcagagcatggccaagtcc
agatatatggagctctacactcatgtttataactactgtactagtgttcaccagtcaaac
caagcacgaggagctggagttcctccttctaagtcgaaaaaggggcagacacctggagga
gctcagtttgttggcctggaattatataaacgacttaaggaatttttgaagaattacttg
acaaatcttcttaaggatggagaagatttgatggatgagagtgtactgaaattctacact
caacaatgggaagattatcgattttcaagcaaagtgctgaatggaatttgtgcctacctc
aatagacattgggttcgccgtgaatgtgacgaaggacgaaaaggaatatatgaaatctat
tcgcttgcattggtgacttggagagactgtctgttcaggccactgaataaacaggtaaca
aatgctgttttaaagctgattgaaaaggaaaggaatggtgaaaccatcaatacaagattg
attagtggagttgtacagtcttacgtggaattggggctgaatgaagatgatgcatttgca
aagggccctacgttaacagtgtataaagaatcctttgaatctcaatttttggctgacaca
gagagattttataccagagagagtactgaattcttgcagcagaacccagttactgaatat
atgaaaaaggcagaggctcgtctgcttgaggaacaacgaagagttcaggtttaccttcat
gaaagcacacaagatgaattagcaaggaaatgtgaacaagtcctcattgaaaaacacttg
gaaattttccacacagaatttcagaatttattggatgctgacaaaaatgaagatttggga
cgcatgtataatcttgtatctagaatccaggatggcctaggagaattgaaaaaactgttg
gagacacacattcataatcagggtcttgcagccattgaaaagtgtggagaagctgcttta
aatgaccccaaaatgtatgtacagacagtgcttgatgttcataaaaaatacaatgccctg
gtaatgtctgcattcaacaatgacgctggctttgtggctgctcttgataaggcttgtggt
cgcttcataaacaacaacgcggttaccaagatggcccaatcatccagtaaatcccctgag
ttgctggctcgatactgtgactccttgttgaagaaaagttccaagaacccagaggaggca
gaactagaagacacactcaatcaagtgatggttgtcttcaagtacatagaagacaaagac
gtatttcagaagttctatgcgaagatgctcgccaagaggctcgtccaccagaacagtgca
agtgacgatgccgaagccagcatgatctccaagttaaagcaagcttgcgggttcgagtac
acctctaaacttcagcgcatgtttcaagacattggcgtgagcaaagatctgaacgagcaa
ttcaaaaagcacttgacaaactcagaacccctagacttggatttcagcattcaagtgctg
agctccgggtcctggcccttccagcagtcttgtacatttgccttgccgtcagagttggaa
cgtagttatcagcgattcacagctttctacgccagccgccacagtggccgaaaattgacg
tggttatatcagttgtctaaaggagaattggtaactaactgcttcaaaaacagatatact
ttgcaggcgtcgacattccagatggctatcctgcttcagtacaacacggaagatgcctac
actgtgcagcagctgaccgacagcactcaaattaaaatggacattttggcgcaagtttta
cagattttattaaagtcgaagctattggtcttggaagatgaaaatgcaaatgttgatgag
gtggaattgaagccagataccttaataaaattatatcttggttataaaaataagaaatta
agggttaacatcaatgtgccaatgaaaaccgaacagaagcaggaacaagaaaccacacac
aaaaacatcgaggaagaccgcaaactactgattcaggcggccatcgtgagaatcatgaag
atgaggaaggttctgaaacaccagcagttacttggcgaggtcctcactcagctgtcctcc
aggttcaaacctcgagtccctgtgatcaagaaatgcattgacattctaattgagaaagaa
tatttggagcgagtggatggtgaaaaggacacctacagttacttggcttaa
Homo sapiens (human): 9978
Help
Entry
9978 CDS
T01001
Symbol
RBX1, BA554C12.1, RNF75, ROC1
Name
(RefSeq) ring-box 1
KO
K03868
E3 ubiquitin-protein ligase RBX1 [EC:
2.3.2.32
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03420
Nucleotide excision repair
hsa04066
HIF-1 signaling pathway
hsa04110
Cell cycle
hsa04114
Oocyte meiosis
hsa04120
Ubiquitin mediated proteolysis
hsa04141
Protein processing in endoplasmic reticulum
hsa04310
Wnt signaling pathway
hsa04350
TGF-beta signaling pathway
hsa04710
Circadian rhythm
hsa05131
Shigellosis
hsa05170
Human immunodeficiency virus 1 infection
hsa05200
Pathways in cancer
hsa05211
Renal cell carcinoma
Network
nt06165
Epstein-Barr virus (EBV)
nt06166
Human papillomavirus (HPV)
nt06182
Shigella
nt06225
HIF-1 signaling (cancer)
nt06230
Cell cycle (cancer)
nt06261
Gastric cancer
nt06264
Renal cell carcinoma
nt06267
Small cell lung cancer
nt06272
Prostate cancer
nt06502
Nucleotide excision repair
nt06509
DNA replication
nt06516
TNF signaling
Element
N00080
Loss of VHL to HIF-1 signaling pathway
N00081
Mutation-inactivated VHL to HIF-1 signaling pathway
N00091
p27-Cell cycle G1/S
N00092
Amplified MYC to p27-cell cycle G1/S
N00942
Shigella OspG to TNF-NFKB signaling pathway
N01425
Global genome NER
N01430
Transcription-coupled NER
N01473
DNA replication termination
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
9978 (RBX1)
04120 Ubiquitin mediated proteolysis
9978 (RBX1)
09124 Replication and repair
03420 Nucleotide excision repair
9978 (RBX1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
9978 (RBX1)
04350 TGF-beta signaling pathway
9978 (RBX1)
04066 HIF-1 signaling pathway
9978 (RBX1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
9978 (RBX1)
04114 Oocyte meiosis
9978 (RBX1)
09150 Organismal Systems
09159 Environmental adaptation
04710 Circadian rhythm
9978 (RBX1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
9978 (RBX1)
09162 Cancer: specific types
05211 Renal cell carcinoma
9978 (RBX1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
9978 (RBX1)
09171 Infectious disease: bacterial
05131 Shigellosis
9978 (RBX1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
9978 (RBX1)
03400 DNA repair and recombination proteins [BR:
hsa03400
]
9978 (RBX1)
Enzymes [BR:
hsa01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.32 cullin-RING-type E3 NEDD8 transferase
9978 (RBX1)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin ligases (E3)
UBL E3 ligases
9978 (RBX1)
Multi subunit Ring-finger type E3
SCF complex
Ring finger protein
9978 (RBX1)
Cul2 complex
9978 (RBX1)
Cul3 complex
9978 (RBX1)
Cul4 complex
9978 (RBX1)
Cul7 complex
9978 (RBX1)
Cul8 complex
9978 (RBX1)
Cul9 complex
9978 (RBX1)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
SSBR (single strand breaks repair)
NER (nucleotide excision repair)
GGR (global genome repair) factors
Cul4-DDB2 complex
9978 (RBX1)
TCR (transcription coupled repair) factors
Cul4-CSA complex
9978 (RBX1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
zf-rbx1
zf-ANAPC11
zf-RING_2
zf-C3HC4
zf-C3HC4_2
zf-RING_11
zf-RING_16
Motif
Other DBs
NCBI-GeneID:
9978
NCBI-ProteinID:
NP_055063
OMIM:
603814
HGNC:
9928
Ensembl:
ENSG00000100387
UniProt:
P62877
Structure
PDB
LinkDB
All DBs
Position
22:40951378..40973309
Genome browser
AA seq
108 aa
AA seq
DB search
MAAAMDVDTPSGTNSGAGKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQ
ASATSEECTVAWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH
NT seq
327 nt
NT seq
+upstream
nt +downstream
nt
atggcggcagcgatggatgtggataccccgagcggcaccaacagcggcgcgggcaagaag
cgctttgaagtgaaaaagtggaatgcagtagccctctgggcctgggatattgtggttgat
aactgtgccatctgcaggaaccacattatggatctttgcatagaatgtcaagctaaccag
gcgtccgctacttcagaagagtgtactgtcgcatggggagtctgtaaccatgcttttcac
ttccactgcatctctcgctggctcaaaacacgacaggtgtgtccattggacaacagagag
tgggaattccaaaagtatgggcactag
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integrated database retrieval system
