Homo sapiens (human): 898 Help Entry 898               CDS       T01001                                  Symbol CCNE1, CCNE, pCCNE1 Name (RefSeq) cyclin E1   KO K06626   G1/S-specific cyclin-E1 Organism hsa  Homo sapiens (human) Pathway hsa04110   Cell cycle hsa04114   Oocyte meiosis hsa04115   p53 signaling pathway hsa04151   PI3K-Akt signaling pathway hsa04218   Cellular senescence hsa04934   Cushing syndrome hsa05161   Hepatitis B hsa05162   Measles hsa05165   Human papillomavirus infection hsa05166   Human T-cell leukemia virus 1 infection hsa05169   Epstein-Barr virus infection hsa05200   Pathways in cancer hsa05203   Viral carcinogenesis hsa05206   MicroRNAs in cancer hsa05215   Prostate cancer hsa05222   Small cell lung cancer hsa05226   Gastric cancer Network   Element N00091   p27-Cell cycle G1/S N00092   Amplified MYC to p27-cell cycle G1/S N00093   Loss of CDKN1B to p27-cell cycle G1/S N00254   CDKN1B-reduced expression to p27-cell cycle G1/S N00255   Amplified CCNE to cell cycle G1/S N00264   EBV EBNA3C to p27-Cell cycle G1/S N00316   Mutation-inactivated CDKN1B to p27-cell cycle G1/S N00360   HPV E7 to p27-cell cycle G1/S N00482   EBV EBNA3C to p27-Cell cycle G1/S N00497   HTLV-1 Tax to p21-cell cycle G1/S N00498   HTLV-1 Tax to p21-cell cycle G1/S N00536   MDM2-p21-Cell cycle G1/S N00537   HBV HBx to cell cycle G1/S N01468   DNA replication licensing Disease H00018   Gastric cancer H00055   Laryngeal cancer Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     898 (CCNE1)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     898 (CCNE1)    04114 Oocyte meiosis     898 (CCNE1)    04115 p53 signaling pathway     898 (CCNE1)    04218 Cellular senescence     898 (CCNE1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     898 (CCNE1)    05206 MicroRNAs in cancer     898 (CCNE1)    05203 Viral carcinogenesis     898 (CCNE1)   09162 Cancer: specific types    05226 Gastric cancer     898 (CCNE1)    05215 Prostate cancer     898 (CCNE1)    05222 Small cell lung cancer     898 (CCNE1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     898 (CCNE1)    05161 Hepatitis B     898 (CCNE1)    05162 Measles     898 (CCNE1)    05169 Epstein-Barr virus infection     898 (CCNE1)    05165 Human papillomavirus infection     898 (CCNE1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     898 (CCNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:hsa03032]     898 (CCNE1)    03036 Chromosome and associated proteins [BR:hsa03036]     898 (CCNE1) DNA replication proteins [BR:hsa03032]  Eukaryotic type   DNA Replication Initiation Factors    CDK (cyclin dependent kinase)     898 (CCNE1) Chromosome and associated proteins [BR:hsa03036]  Eukaryotic type   Centrosome formation proteins    Cyclins     898 (CCNE1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Cyclin_N Cyclin_C Motif Other DBs NCBI-GeneID:  898 NCBI-ProteinID:  NP_001229 OMIM:  123837 HGNC:  1589 Ensembl:  ENSG00000105173 UniProt:  P24864 Structure PDB LinkDB All DBs Position 19:29811991..29824312 Genome browser AA seq 410 aa AA seqDB search MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQ PWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIM LNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQ ENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWR LSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILA ASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNI QTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA NT seq 1233 nt NT seq  +upstreamnt  +downstreamnt atgccgagggagcgcagggagcgggatgcgaaggagcgggacaccatgaaggaggacggc ggcgcggagttctcggctcgctccaggaagaggaaggcaaacgtgaccgtttttttgcag gatccagatgaagaaatggccaaaatcgacaggacggcgagggaccagtgtgggagccag ccttgggacaataatgcagtctgtgcagacccctgctccctgatccccacacctgacaaa gaagatgatgaccgggtttacccaaactcaacgtgcaagcctcggattattgcaccatcc agaggctccccgctgcctgtactgagctgggcaaatagagaggaagtctggaaaatcatg ttaaacaaggaaaagacatacttaagggatcagcactttcttgagcaacaccctcttctg cagccaaaaatgcgagcaattcttctggattggttaatggaggtgtgtgaagtctataaa cttcacagggagaccttttacttggcacaagatttctttgaccggtatatggcgacacaa gaaaatgttgtaaaaactcttttacagcttattgggatttcatctttatttattgcagcc aaacttgaggaaatctatcctccaaagttgcaccagtttgcgtatgtgacagatggagct tgttcaggagatgaaattctcaccatggaattaatgattatgaaggcccttaagtggcgt ttaagtcccctgactattgtgtcctggctgaatgtatacatgcaggttgcatatctaaat gacttacatgaagtgctactgccgcagtatccccagcaaatctttatacagattgcagag ctgttggatctctgtgtcctggatgttgactgccttgaatttccttatggtatacttgct gcttcggccttgtatcatttctcgtcatctgaattgatgcaaaaggtttcagggtatcag tggtgcgacatagagaactgtgtcaagtggatggttccatttgccatggttataagggag acggggagctcaaaactgaagcacttcaggggcgtcgctgatgaagatgcacacaacata cagacccacagagacagcttggatttgctggacaaagcccgagcaaagaaagccatgttg tctgaacaaaatagggcttctcctctccccagtgggctcctcaccccgccacagagcggt aagaagcagagcagcgggccggaaatggcgtga

Homo sapiens (human): 9134 Help Entry 9134              CDS       T01001                                  Symbol CCNE2, CYCE2 Name (RefSeq) cyclin E2   KO K06626   G1/S-specific cyclin-E1 Organism hsa  Homo sapiens (human) Pathway hsa04110   Cell cycle hsa04114   Oocyte meiosis hsa04115   p53 signaling pathway hsa04151   PI3K-Akt signaling pathway hsa04218   Cellular senescence hsa04934   Cushing syndrome hsa05161   Hepatitis B hsa05162   Measles hsa05165   Human papillomavirus infection hsa05166   Human T-cell leukemia virus 1 infection hsa05169   Epstein-Barr virus infection hsa05200   Pathways in cancer hsa05203   Viral carcinogenesis hsa05206   MicroRNAs in cancer hsa05215   Prostate cancer hsa05222   Small cell lung cancer hsa05226   Gastric cancer Network   Element N00091   p27-Cell cycle G1/S N00092   Amplified MYC to p27-cell cycle G1/S N00093   Loss of CDKN1B to p27-cell cycle G1/S N00254   CDKN1B-reduced expression to p27-cell cycle G1/S N00264   EBV EBNA3C to p27-Cell cycle G1/S N00316   Mutation-inactivated CDKN1B to p27-cell cycle G1/S N00360   HPV E7 to p27-cell cycle G1/S N00482   EBV EBNA3C to p27-Cell cycle G1/S N00497   HTLV-1 Tax to p21-cell cycle G1/S N00498   HTLV-1 Tax to p21-cell cycle G1/S N00536   MDM2-p21-Cell cycle G1/S N00537   HBV HBx to cell cycle G1/S N01468   DNA replication licensing Disease H00055   Laryngeal cancer Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     9134 (CCNE2)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     9134 (CCNE2)    04114 Oocyte meiosis     9134 (CCNE2)    04115 p53 signaling pathway     9134 (CCNE2)    04218 Cellular senescence     9134 (CCNE2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     9134 (CCNE2)    05206 MicroRNAs in cancer     9134 (CCNE2)    05203 Viral carcinogenesis     9134 (CCNE2)   09162 Cancer: specific types    05226 Gastric cancer     9134 (CCNE2)    05215 Prostate cancer     9134 (CCNE2)    05222 Small cell lung cancer     9134 (CCNE2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     9134 (CCNE2)    05161 Hepatitis B     9134 (CCNE2)    05162 Measles     9134 (CCNE2)    05169 Epstein-Barr virus infection     9134 (CCNE2)    05165 Human papillomavirus infection     9134 (CCNE2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     9134 (CCNE2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:hsa03032]     9134 (CCNE2)    03036 Chromosome and associated proteins [BR:hsa03036]     9134 (CCNE2) DNA replication proteins [BR:hsa03032]  Eukaryotic type   DNA Replication Initiation Factors    CDK (cyclin dependent kinase)     9134 (CCNE2) Chromosome and associated proteins [BR:hsa03036]  Eukaryotic type   Centrosome formation proteins    Cyclins     9134 (CCNE2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Cyclin_N Cyclin_C Motif Other DBs NCBI-GeneID:  9134 NCBI-ProteinID:  NP_477097 OMIM:  603775 HGNC:  1590 Ensembl:  ENSG00000175305 UniProt:  O96020 LinkDB All DBs Position 8:complement(94880224..94896693) Genome browser AA seq 404 aa AA seqDB search MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPP VLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKK ESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDI NKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCP VTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAA LCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTH TNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH NT seq 1215 nt NT seq  +upstreamnt  +downstreamnt atgtcaagacgaagtagccgtttacaagctaagcagcagccccagcccagccagacggaa tccccccaagaagcccagataatccaggccaagaagaggaaaactacccaggatgtcaaa aaaagaagagaggaggtcaccaagaaacatcagtatgaaattaggaattgttggccacct gtattatctggggggatcagtccttgcattatcattgaaacacctcacaaagaaatagga acaagtgatttctccagatttacaaattacagatttaaaaatctttttattaatccttca cctttgcctgatttaagctggggatgttcaaaagaagtctggctaaacatgttaaaaaag gagagcagatatgttcatgacaaacattttgaagttctgcattctgacttggaaccacag atgaggtccatacttctagactggcttttagaggtatgtgaagtatacacacttcatagg gaaacattttatcttgcacaagacttttttgatagatttatgttgacacaaaaggatata aataaaaatatgcttcaactcattggaattacctcattattcattgcttccaaacttgag gaaatctatgctcctaaactccaagagtttgcttacgtcactgatggtgcttgcagtgaa gaggatatcttaaggatggaactcattatattaaaggctttaaaatgggaactttgtcct gtaacaatcatctcctggctaaatctctttctccaagttgatgctcttaaagatgctcct aaagttcttctacctcagtattctcaggaaacattcattcaaatagctcagcttttagat ctgtgtattctagccattgattcattagagttccagtacagaatactgactgctgctgcc ttgtgccattttacctccattgaagtggttaagaaagcctcaggtttggagtgggacagt atttcagaatgtgtagattggatggtaccttttgtcaatgtagtaaaaagtactagtcca gtgaagctgaagacttttaagaagattcctatggaagacagacataatatccagacacat acaaactatttggctatgctggaggaagtaaattacataaacaccttcagaaaaggggga cagttgtcaccagtgtgcaatggaggcattatgacaccaccgaagagcactgaaaaacca ccaggaaaacactaa

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