PATHWAY: ko00626 Help
Entry Name Naphthalene degradation
Class Metabolism; Xenobiotics biodegradation and metabolismBRITE hierarchy
Pathway map Module M00534 Naphthalene degradation, naphthalene => salicylate [PATH:ko00626 ]
M00638 Salicylate degradation, salicylate => gentisate [PATH:ko00626 ]
Other DBs Orthology K00121 frmA, ADH5, adhC; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1 ]
K01670 nmsA; naphthyl-2-methylsuccinate synthase alpha subunit [EC:4.1.99.-]
K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1 ]
K14578 nahAb, nagAb, ndoA, nbzAb, dntAb; naphthalene 1,2-dioxygenase ferredoxin component
K14581 nahAa, nagAa, ndoR, nbzAa, dntAa; naphthalene 1,2-dioxygenase ferredoxin reductase component [EC:1.18.1.7 ]
K14582 nahB, doxE; cis-1,2-dihydro-1,2-dihydroxynaphthalene/dibenzothiophene dihydrodiol dehydrogenase [EC:1.3.1.29 1.3.1.60 ]
K14585 nahE; trans-o-hydroxybenzylidenepyruvate hydratase-aldolase [EC:4.1.2.45 ]
K14586 nmoAB; 2-naphthoate monooxygenase
K15567 nmsB; naphthyl-2-methylsuccinate synthase beta subunit [EC:4.1.99.-]
K15568 nmsC; naphthyl-2-methylsuccinate synthase gamma subunit [EC:4.1.99.-]
K15569 bnsE; naphthyl-2-methylsuccinate CoA transferase subunit [EC:2.8.3.-]
K15570 bnsF; naphthyl-2-methylsuccinate CoA transferase subunit [EC:2.8.3.-]
K15571 bnsG; naphthyl-2-methylsuccinyl-CoA dehydrogenase [EC:1.3.99.-]
K15572 bnsH; naphthyl-2-hydroxymethylsuccinyl-CoA hydratase [EC:4.2.1.-]
K15573 bnsC; naphthyl-2-hydroxymethylsuccinyl-CoA dehydrogenase BnsC subunit [EC:1.1.-.-]
K15574 bnsA; naphthyl-2-oxomethyl-succinyl-CoA thiolase subunit [EC:2.3.1.-]
K15575 bnsB; naphthyl-2-oxomethyl-succinyl-CoA thiolase subunit [EC:2.3.1.-]
K19958 bnsD; naphthyl-2-hydroxymethylsuccinyl-CoA dehydrogenase BnsD subunit [EC:1.1.-.-]
Compound C04314 cis-1,2-Dihydronaphthalene-1,2-diol
C06203 trans-o-Hydroxybenzylidenepyruvate
C06204 2-Hydroxychromene-2-carboxylate
C14083 cis-1,2-Dihydroxy-1,2-dihydro-8-methylnaphthalene
C14084 1,2-Dihydroxy-8-methylnaphthalene
C14085 2-Hydroxy-8-methylchromene-2-carboxylate
C14086 2-Hydroxy-3-methylbenzalpyruvate
C14087 3-Methylsalicylaldehyde
C14089 1-Hydroxymethylnaphthalene
C14092 cis-1,2-Dihydroxy-1,2-dihydro-8-carboxynaphthalene
C14093 1,2-Dihydroxy-8-carboxynaphthalene
C14094 2-Carboxy-2-hydroxy-8-carboxychromene
C14095 2-Hydroxy-3-carboxybenzalpyruvate
C14097 2-Hydroxyisophthalic acid
C14102 cis-1,2-Dihydroxy-1,2-dihydro-7-methylnaphthalene
C14104 cis-1,2-Dihydroxy-1,2-dihydro-7-hydroxymethylnaphthalene
C14105 1,2-Dihydroxy-7-hydroxymethylnaphthalene
C14106 2-Hydroxy-7-hydroxymethylchromene-2-carboxylate
C14107 2-Hydroxy-4-hydroxymethylbenzalpyruvate
C14108 4-Hydroxymethylsalicylaldehyde
C14109 4-Hydroxymethylsalicylate
C14110 4-Hydroxymethylcatechol
C14111 5,6,7,8-Tetrahydro-2-naphthoic acid
C14112 cis-2-Carboxycyclohexyl-acetic acid
C14113 Decahydro-2-naphthoic acid
C14115 2-Naphtylmethylsuccinic acid
C14116 Naphthyl-2-methyl-succinyl-CoA
C14117 Naphthyl-2-methylene-succinyl-CoA
C14118 Naphthyl-2-hydroxymethyl-succinyl CoA
C14119 Naphthyl-2-oxomethyl-succinyl-CoA
C16193 1,6-Naphthalenedisulfonic acid
C16194 2,6-Naphthalenedisulfonic acid
C16196 1,2-Dihydroxynaphthalene-6-sulfonate
C16198 (Z)-4-(2-Hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate
C16201 1-Naphthalenesulfonic acid
C16202 2-Naphthalenesulfonic acid
Reference Authors Kim SJ, Kweon O, Freeman JP, Jones RC, Adjei MD, Jhoo JW, Edmondson RD, Cerniglia CE.
Title Molecular cloning and expression of genes encoding a novel dioxygenase involved in low- and high-molecular-weight polycyclic aromatic hydrocarbon degradation in Mycobacterium vanbaalenii PYR-1.
Journal Reference Authors Denome SA, Stanley DC, Olson ES, Young KD
Title Metabolism of dibenzothiophene and naphthalene in Pseudomonas strains: complete DNA sequence of an upper naphthalene catabolic pathway.
Journal Reference Authors Eaton RW, Chapman PJ
Title Bacterial metabolism of naphthalene: construction and use of recombinant bacteria to study ring cleavage of 1,2-dihydroxynaphthalene and subsequent reactions.
Journal Reference Authors Morawski B, Eaton RW, Rossiter JT, Guoping S, Griengl H, Ribbons DW
Title 2-Naphthoate catabolic pathway in Burkholderia strain JT 1500.
Journal Reference Authors Safinowski M, Meckenstock RU
Title Enzymatic reactions in anaerobic 2-methylnaphthalene degradation by the sulphate-reducing enrichment culture N 47.
Journal Reference Authors Annweiler E, Materna A, Safinowski M, Kappler A, Richnow HH, Michaelis W, Meckenstock RU
Title Anaerobic degradation of 2-methylnaphthalene by a sulfate-reducing enrichment culture.
Journal Reference Authors Annweiler E, Michaelis W, Meckenstock RU
Title Identical ring cleavage products during anaerobic degradation of naphthalene, 2-methylnaphthalene, and tetralin indicate a new metabolic pathway.
Journal Reference Authors Aitken CM, Jones DM, Larter SR
Title Anaerobic hydrocarbon biodegradation in deep subsurface oil reservoirs.
Journal Reference Authors Selesi D, Jehmlich N, von Bergen M, Schmidt F, Rattei T, Tischler P, Lueders T, Meckenstock RU
Title Combined genomic and proteomic approaches identify gene clusters involved in anaerobic 2-methylnaphthalene degradation in the sulfate-reducing enrichment culture N47.
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