PATHWAY: ko00362 Help
Entry
Name
Benzoate degradation
Class
Metabolism; Xenobiotics biodegradation and metabolism
BRITE hierarchy
Pathway map
Ortholog table
Module
M00540 Benzoate degradation, cyclohexanecarboxylic acid =>pimeloyl-CoA [PATH:ko00362 ]
M00541 Benzoyl-CoA degradation, benzoyl-CoA => 3-hydroxypimeloyl-CoA [PATH:ko00362 ]
M00547 Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol [PATH:ko00362 ]
M00551 Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol [PATH:ko00362 ]
M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH:ko00362 ]
M00569 Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA [PATH:ko00362 ]
Other DBs
Orthology
K05784 benzoate/toluate 1,2-dioxygenase reductase component [EC:1.18.1.-]
K05783 dihydroxycyclohexadiene carboxylate dehydrogenase [EC:1.3.1.25 1.3.1.-]
K18089 benzene/toluene/chlorobenzene dioxygenase ferredoxin component
K18090 benzene/toluene/chlorobenzene dioxygenase ferredoxin reductase component [EC:1.18.1.3 1.18.1.-]
K16249 phenol/toluene 2-monooxygenase (NADH) P0/A0
K10621 2,3-dihydroxy-p-cumate/2,3-dihydroxybenzoate 3,4-dioxygenase [EC:1.13.11.- 1.13.11.14 ]
K10622 HCOMODA/2-hydroxy-3-carboxy-muconic semialdehyde decarboxylase [EC:4.1.1.-]
K10219 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase [EC:1.1.1.312 ]
K00529 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3 ]
K27674 4-oxocyclohex-2-ene-1-carboxylate desaturase
K19515 benzoyl-CoA reductase subunit BamB [EC:1.3.-.-]
K19516 benzoyl-CoA reductase subunit BamC [EC:1.3.-.-]
K04116 cyclohexanecarboxylate-CoA ligase [EC:6.2.1.-]
K27540 succinyl-CoA:cyclohexane-1-carboxylate CoA transferase [EC:2.3.1.315 ]
K04117 cyclohexanecarboxyl-CoA dehydrogenase [EC:1.3.99.-]
K07534 cyclohex-1-ene-1-carboxyl-CoA hydratase [EC:4.2.1.-]
K07535 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase [EC:1.1.1.-]
K07536 2-ketocyclohexanecarboxyl-CoA hydrolase [EC:3.1.2.-]
K23351 glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
K23352 glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit delta
Compound
C00596 2-Hydroxy-2,4-pentadienoate
C00682 2-Hydroxymuconate semialdehyde
C01144 (S)-3-Hydroxybutanoyl-CoA
C01163 3-Carboxy-cis,cis-muconate
C01278 2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate
C03586 2-Oxo-2,3-dihydrofuran-5-acetate
C03589 4-Hydroxy-2-oxopentanoate
C03671 2-Pyrone-4,6-dicarboxylate
C03676 3-Hydroxy-cis,cis-muconate
C03767 4-Oxocyclohexanecarboxylate
C04091 cis-1,2-Dihydrobenzene-1,2-diol
C04115 4-Carboxy-4-hydroxy-2-oxoadipate
C04324 (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate
C04404 trans-4-Hydroxycyclohexanecarboxylate
C04434 (1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate
C04480 3-Carboxy-2-hydroxymuconate semialdehyde
C04484 4-Carboxy-2-hydroxymuconate semialdehyde
C04553 3-Carboxy-2,5-dihydro-5-oxofuran-2-acetate
C05375 2-Hydroxy-2-hydropyrone-4,6-dicarboxylate
C06035 4-Methylene-2-oxoglutarate
C06321 (1R,6S)-1,6-Dihydroxycyclohexa-2,4-diene-1-carboxylate
C06322 Cyclohexa-1,5-diene-1-carbonyl-CoA
C06333 2-Aminobenzenesulfonate
C06723 6-Carboxyhex-2-enoyl-CoA
C06749 6-Hydroxycyclohex-1-ene-1-carbonyl-CoA
C09809 Cyclohexa-2,5-diene-1-carbonyl-CoA
C09810 Cyclohexa-1,4-diene-1-carbonyl-CoA
C09811 Cyclohex-1-ene-1-carbonyl-CoA
C09812 2-Hydroxycyclohexane-1-carbonyl-CoA
C09813 2-Oxocyclohexane-1-carbonyl-CoA
C09821 6-Oxocyclohex-1-ene-1-carbonyl-CoA
C09822 Cyclohexane-1-carboxylate
C09823 Cyclohexane-1-carbonyl-CoA
C14144 5-Carboxy-2-pentenoyl-CoA
C14610 (S)-5-Oxo-2,5-dihydrofuran-2-acetate
C19682 3,4-Didehydroadipyl-CoA
C19683 3,4-Didehydroadipyl-CoA semialdehyde
C19684 2,3-Epoxy-2,3-dihydrobenzoyl-CoA
C22885 cis-4-Hydroxycyclohexane-1-carboxylate
C22887 4-Oxocyclohex-2-ene-1-carboxylate
C22920 4-Oxocyclohex-2,5-dienecarboxylate
Reference
Authors
Carmona M, Zamarro MT, Blazquez B, Durante-Rodriguez G, Juarez JF, Valderrama JA, Barragan MJ, Garcia JL, Diaz E
Title
Anaerobic catabolism of aromatic compounds: a genetic and genomic view.
Journal
Reference
Authors
Hara H, Masai E, Miyauchi K, Katayama Y, Fukuda M.
Title
Characterization of the 4-carboxy-4-hydroxy-2-oxoadipate aldolase gene and operon structure of the protocatechuate 4,5-cleavage pathway genes in Sphingomonas paucimobilis SYK-6.
Journal
Reference
Authors
Maruyama K, Shibayama T, Ichikawa A, Sakou Y, Yamada S, Sugisaki H.
Title
Cloning and characterization of the genes encoding enzymes for the protocatechuate meta-degradation pathway of Pseudomonas ochraceae NGJ1.
Journal
Reference
Authors
Mampel J, Ruff J, Junker F, Cook AM.
Title
The oxygenase component of the 2-aminobenzenesulfonate dioxygenase system from Alcaligenes sp. strain O-1.
Journal
Reference
Authors
Junker F, Field JA, Bangerter F, Ramsteiner K, Kohler HP, Joannou CL, Mason JR, Leisinger T, Cook AM.
Title
Oxygenation and spontaneous deamination of 2-aminobenzenesulphonic acid in Alcaligenes sp. strain O-1 with subsequent meta ring cleavage and spontaneous desulphonation to 2-hydroxymuconic acid.
Journal
Reference
Authors
Harwood CS, Gibson J.
Title
Shedding light on anaerobic benzene ring degradation: a process unique to prokaryotes?
Journal
Reference
Authors
Peters F, Shinoda Y, McInerney MJ, Boll M.
Title
Cyclohexa-1,5-diene-1-carbonyl-coenzyme A (CoA) hydratases of Geobacter metallireducens and Syntrophus aciditrophicus: Evidence for a common benzoyl-CoA degradation pathway in facultative and strict anaerobes.
Journal
Reference
Authors
Cowles CE, Nichols NN, Harwood CS.
Title
BenR, a XylS homologue, regulates three different pathways of aromatic acid degradation in Pseudomonas putida.
Journal
Reference
Authors
Smith MA, Weaver VB, Young DM, Ornston LN.
Title
Genes for chlorogenate and hydroxycinnamate catabolism (hca) are linked to functionally related genes in the dca-pca-qui-pob-hca chromosomal cluster of Acinetobacter sp. strain ADP1.
Journal
Reference
Authors
Kuntze K, Shinoda Y, Moutakki H, McInerney MJ, Vogt C, Richnow HH, Boll M
Title
6-Oxocyclohex-1-ene-1-carbonyl-coenzyme A hydrolases from obligately anaerobic bacteria: characterization and identification of its gene as a functional marker for aromatic compounds degrading anaerobes.
Journal
Reference
Authors
Pelletier DA, Harwood CS
Title
2-Hydroxycyclohexanecarboxyl coenzyme A dehydrogenase, an enzyme characteristic of the anaerobic benzoate degradation pathway used by Rhodopseudomonas palustris.
Journal
Reference
Authors
Elshahed MS, Bhupathiraju VK, Wofford NQ, Nanny MA, McInerney MJ
Title
Metabolism of benzoate, cyclohex-1-ene carboxylate, and cyclohexane carboxylate by "Syntrophus aciditrophicus" strain SB in syntrophic association with H(2)-using microorganisms.
Journal
Reference
Authors
Nogales J, Canales A, Jimenez-Barbero J, Serra B, Pingarron JM, Garcia JL, Diaz E
Title
Unravelling the gallic acid degradation pathway in bacteria: the gal cluster from Pseudomonas putida.
Journal
Related pathway
ko00010 Glycolysis / Gluconeogenesis
ko00361 Chlorocyclohexane and chlorobenzene degradation
LinkDB
All DBs