| Entry |
|
| Symbol |
KDSR, kdsr
|
| Name |
3-dehydrosphinganine reductase [EC: 1.1.1.102]
|
| Pathway |
|
| Module |
| M00099 | Sphingosine biosynthesis |
|
| Reaction |
| R02978 | sphinganine:NADP+ 3-oxidoreductase |
|
| Disease |
| H00710 | Erythrokeratodermia variabilis |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09103 Lipid metabolism
00600 Sphingolipid metabolism
K04708 KDSR, kdsr; 3-dehydrosphinganine reductase
09150 Organismal Systems
09158 Development and regeneration
04382 Cornified envelope formation
K04708 KDSR, kdsr; 3-dehydrosphinganine reductase
Enzymes [BR:ko01000]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.102 3-dehydrosphinganine reductase
K04708 KDSR, kdsr; 3-dehydrosphinganine reductase
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| Other DBs |
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| Genes |
» show all
|
| Reference |
|
| Authors |
Kihara A, Igarashi Y |
| Title |
FVT-1 is a mammalian 3-ketodihydrosphingosine reductase with an active site that faces the cytosolic side of the endoplasmic reticulum membrane. |
| Journal |
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| Sequence |
|
| Reference |
|
| Authors |
Lee MT, Le HH, Besler KR, Johnson EL |
| Title |
Identification and characterization of 3-ketosphinganine reductase activity encoded at the BT_0972 locus in Bacteroides thetaiotaomicron. |
| Journal |
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| Sequence |
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| LinkDB |
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