KEGG   PATHWAY: mbb00250
Entry
mbb00250                    Pathway                                
Name
Alanine, aspartate and glutamate metabolism - Mycobacterium tuberculosis variant bovis BCG Pasteur 1173P2
Class
Metabolism; Amino acid metabolism
Pathway map
mbb00250  Alanine, aspartate and glutamate metabolism
mbb00250

Module
mbb_M00027  GABA (gamma-Aminobutyrate) shunt [PATH:mbb00250]
Other DBs
GO: 0006522 0006531 0006536
Organism
Mycobacterium tuberculosis variant bovis BCG Pasteur 1173P2 [GN:mbb]
Gene
BCG_0271c  gabD1; Probable succinate-semialdehyde dehydrogenase [nadp+] dependant (ssdh) gabD1 [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
BCG_0376c  aspC; Probable aspartate aminotransferase aspC [KO:K14260] [EC:2.6.1.66 2.6.1.2]
BCG_0395c  purA; Probable adenylosuccinate synthetase purA [KO:K01939] [EC:6.3.4.4]
BCG_0829  purB; Probable adenylosuccinate lyase purB [KO:K01756] [EC:4.3.2.2]
BCG_0841  purQ; Probable phosphoribosylformylglycinamidine synthase I purG [KO:K23265]
BCG_0860  purF; Probable amidophosphoribosyltransferase purF [KO:K00764] [EC:2.4.2.14]
BCG_1249  rocA; Probable pyrroline-5-carboxylate dehydrogenase rocA [KO:K00294] [EC:1.2.1.88]
BCG_1441  pyrB; Probable aspartate carbamoyltransferase pyrB [KO:K00609] [EC:2.1.3.2]
BCG_1444  carA; Probable carbamoyl-phosphate synthase small chain carA [KO:K01956] [EC:6.3.5.5]
BCG_1445  carB; Probable carbamoyl-phosphate synthase large chain carB [KO:K01955] [EC:6.3.5.5]
BCG_1590c  ansA; Probable L-aparaginase ansA [KO:K01424] [EC:3.5.1.1]
BCG_1633  nadB; Probable L-aspartate oxidase nadB [KO:K00278] [EC:1.4.3.16]
BCG_1697  argG; Probable Argininosuccinate synthase argG [KO:K01940] [EC:6.3.4.5]
BCG_1698  argH; Probable Argininosuccinate lyase argH [KO:K01755] [EC:4.3.2.1]
BCG_1770  gabD2; Possible succinate-semialdehyde dehydrogenase [nadp+] dependant (ssdh) gabD2 [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
BCG_1915  glnA3; Probable glutamine synthetase glnA3 [KO:K01915] [EC:6.3.1.2]
BCG_2217  asnB; Probable asparagine synthetase AsnB [KO:K01953] [EC:6.3.5.4]
BCG_2237  glnA1; Glutamine synthetase glnA1 [KO:K01915] [EC:6.3.1.2]
BCG_2239c  glnA2; Probable glutamine synthetase glnA2 [KO:K01915] [EC:6.3.1.2]
BCG_2496c  gdh; Probable nad-dependent glutamate dehydrogenase gdh [KO:K15371] [EC:1.4.1.2]
BCG_2612  gabT; 4-aminobutyrate aminotransferase gabT [KO:K07250] [EC:2.6.1.19 2.6.1.22 2.6.1.48]
BCG_2798  aldb; Secreted l-alanine dehydrogenase aldb [second part] [KO:K00259] [EC:1.4.1.1]
BCG_2882c  glnA4; Probable glutamine synthetase glnA4 [KO:K01915] [EC:6.3.1.2]
BCG_3498c  gadB; Probable glutamate decarboxylase gadB [KO:K01580] [EC:4.1.1.15]
BCG_3502c  glmS; Probable glucosamine--fructose-6-phosphate Aminotransferase [isomerizing] glmS [KO:K00820] [EC:2.6.1.16]
BCG_3921c  gltD; Putative NADH-dependent glutamate synthase (small subunit) gltD [KO:K00266] [EC:1.4.1.13]
BCG_3922c  gltB; Putative ferredoxin-dependent glutamate synthase [NADPH] (large subunit) gltB [KO:K00265] [EC:1.4.1.13]
Compound
C00014  Ammonia
C00022  Pyruvate
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00036  Oxaloacetate
C00041  L-Alanine
C00042  Succinate
C00049  L-Aspartate
C00064  L-Glutamine
C00122  Fumarate
C00152  L-Asparagine
C00158  Citrate
C00169  Carbamoyl phosphate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00352  D-Glucosamine 6-phosphate
C00402  D-Aspartate
C00438  N-Carbamoyl-L-aspartate
C00940  2-Oxoglutaramate
C01042  N-Acetyl-L-aspartate
C02362  2-Oxosuccinamate
C03090  5-Phosphoribosylamine
C03406  N-(L-Arginino)succinate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03912  (S)-1-Pyrroline-5-carboxylate
C12270  N-Acetylaspartylglutamate
C20775  beta-Citryl-L-glutamate
C20776  N-Acetylaspartylglutamylglutamate
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:9687539
  Authors
Wu G
  Title
Intestinal mucosal amino acid catabolism.
  Journal
J Nutr 128:1249-52 (1998)
DOI:10.1093/jn/128.8.1249
Related
pathway
mbb00010  Glycolysis / Gluconeogenesis
mbb00020  Citrate cycle (TCA cycle)
mbb00220  Arginine biosynthesis
mbb00230  Purine metabolism
mbb00240  Pyrimidine metabolism
mbb00260  Glycine, serine and threonine metabolism
mbb00261  Monobactam biosynthesis
mbb00300  Lysine biosynthesis
mbb00330  Arginine and proline metabolism
mbb00340  Histidine metabolism
mbb00410  beta-Alanine metabolism
mbb00460  Cyanoamino acid metabolism
mbb00470  D-Amino acid metabolism
mbb00480  Glutathione metabolism
mbb00520  Amino sugar and nucleotide sugar metabolism
mbb00620  Pyruvate metabolism
mbb00630  Glyoxylate and dicarboxylate metabolism
mbb00650  Butanoate metabolism
mbb00660  C5-Branched dibasic acid metabolism
mbb00760  Nicotinate and nicotinamide metabolism
mbb00770  Pantothenate and CoA biosynthesis
mbb00860  Porphyrin metabolism
mbb00910  Nitrogen metabolism
KO pathway
ko00250   

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