KEGG   PATHWAY: mcro00630
Entry
mcro00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycolicibacterium crocinum
Class
Metabolism; Carbohydrate metabolism
Pathway map
mcro00630  Glyoxylate and dicarboxylate metabolism
mcro00630

Module
mcro_M00621  Glycine cleavage system [PATH:mcro00630]
mcro_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mcro00630]
Other DBs
GO: 0046487 0043648
Organism
Mycolicibacterium crocinum [GN:mcro]
Gene
MI149_17520  aceA; isocitrate lyase ICL2 [KO:K01637] [EC:4.1.3.1]
MI149_04065  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
MI149_26860  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
MI149_12830  acsA; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
MI149_17075  malate synthase G [KO:K01638] [EC:2.3.3.9]
MI149_24685  citrate synthase [KO:K01647] [EC:2.3.3.1]
MI149_24710  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
MI149_14205  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
MI149_16885  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MI149_21660  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MI149_21745  thiolase family protein [KO:K00626] [EC:2.3.1.9]
MI149_22225  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MI149_24120  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MI149_24430  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
MI149_24890  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MI149_25150  thiolase family protein [KO:K00626] [EC:2.3.1.9]
MI149_25205  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MI149_26090  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
MI149_26225  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
MI149_26290  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MI149_02170  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MI149_06525  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
MI149_07840  thiolase family protein [KO:K00626] [EC:2.3.1.9]
MI149_22230  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
MI149_08220  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
MI149_08250  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
MI149_08245  acyl-CoA carboxylase subunit epsilon [KO:K27095]
MI149_19460  acyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
MI149_14280  mutA; methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
MI149_14285  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
MI149_21990  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
MI149_21995  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
MI149_21295  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
MI149_22830  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
MI149_27220  catalase [KO:K03781] [EC:1.11.1.6]
MI149_13350  catalase family peroxidase [KO:K03781] [EC:1.11.1.6]
MI149_19275  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
MI149_09350  form I ribulose bisphosphate carboxylase large subunit [KO:K01601] [EC:4.1.1.39]
MI149_09345  ribulose bisphosphate carboxylase small subunit [KO:K01602] [EC:4.1.1.39]
MI149_16765  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
MI149_19130  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
MI149_19160  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
MI149_20220  glnT; type III glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
MI149_20625  glutamine synthetase III [KO:K01915] [EC:6.3.1.2]
MI149_27265  glnT; type III glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
MI149_11585  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
MI149_06635  glycine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
MI149_17090  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
MI149_19070  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
MI149_04040  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
MI149_17115  gcvH; glycine cleavage system protein GcvH [KO:K02437]
MI149_20555  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
MI149_19035  glycerate kinase [KO:K00865] [EC:2.7.1.165]
MI149_22970  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
MI149_12625  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
MI149_12630  4Fe-4S dicluster domain-containing protein [KO:K00124]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mcro00010  Glycolysis / Gluconeogenesis
mcro00020  Citrate cycle (TCA cycle)
mcro00030  Pentose phosphate pathway
mcro00053  Ascorbate and aldarate metabolism
mcro00071  Fatty acid degradation
mcro00230  Purine metabolism
mcro00250  Alanine, aspartate and glutamate metabolism
mcro00260  Glycine, serine and threonine metabolism
mcro00620  Pyruvate metabolism
mcro00710  Carbon fixation by Calvin cycle
mcro00750  Vitamin B6 metabolism
mcro00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

DBGET integrated database retrieval system