Entry Name Lysine biosynthesis - Mycolicibacterium neoaurum VKM Ac-1815D
Class Metabolism; Amino acid metabolismBRITE hierarchy 
Pathway map Module Other DBs Organism Mycolicibacterium neoaurum VKM Ac-1815D [GN:
mne ]
Gene Compound C00441   L-Aspartate 4-semialdehyde 
C00449   N6-(L-1,3-Dicarboxypropyl)-L-lysine 
C00666   LL-2,6-Diaminoheptanedioate 
C00680   meso-2,6-Diaminoheptanedioate 
C01251   (R)-2-Hydroxybutane-1,2,4-tricarboxylate 
C03871   L-2-Amino-6-oxoheptanedioate 
C03972   2,3,4,5-Tetrahydrodipicolinate 
C04002   (Z)-But-1-ene-1,2,4-tricarboxylate 
C04076   L-2-Aminoadipate 6-semialdehyde 
C04390   N6-Acetyl-LL-2,6-diaminoheptanedioate 
C04421   N-Succinyl-LL-2,6-diaminoheptanedioate 
C04462   N-Succinyl-2-L-amino-6-oxoheptanedioate 
C04877   UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate 
C04882   UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine 
C05535   alpha-Aminoadipoyl-S-acyl enzyme 
C05539   N-Acetyl-L-2-amino-6-oxopimelate 
C05560   L-2-Aminoadipate adenylate 
C19886   LysW-gamma-L-alpha-aminoadipate 
C19887   LysW-gamma-L-alpha-aminoadipyl 6-phosphate 
C19888   LysW-gamma-L-alpha-aminoadipate 6-semialdehyde 
C20258   (2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate 
C20277   (2R,3R)-3-Methylornithine 
C20278   (2R,3R)-3-Methylornithinyl-N6-lysine 
C20279   (2R,3R)-3-Methylglutamyl-5-semialdehyde-N6-lysine 
Reference   Authors Ledwidge R, Blanchard JS.
  Title The dual biosynthetic capability of N-acetylornithine aminotransferase in arginine and lysine biosynthesis.
  Journal Reference   Authors Fuchs TM, Schneider B, Krumbach K, Eggeling L, Gross R.
  Title Characterization of a bordetella pertussis diaminopimelate (DAP) biosynthesis locus identifies dapC, a novel gene coding for an N-succinyl-L,L-DAP aminotransferase.
  Journal Reference   Authors Zabriskie TM, Jackson MD.
  Title Lysine biosynthesis and metabolism in fungi.
  Journal Reference   Authors Rodionov DA, Vitreschak AG, Mironov AA, Gelfand MS.
  Title Regulation of lysine biosynthesis and transport genes in bacteria: yet another RNA riboswitch?
  Journal Reference   Authors Velasco AM, Leguina JI, Lazcano A.
  Title Molecular evolution of the lysine biosynthetic pathways.
  Journal Reference   Authors Miyazaki T, Miyazaki J, Yamane H, Nishiyama M.
  Title alpha-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus.
  Journal Reference   Authors Goh DL, Patel A, Thomas GH, Salomons GS, Schor DS, Jakobs C, Geraghty MT.
  Title Characterization of the human gene encoding alpha-aminoadipate aminotransferase (AADAT).
  Journal Reference   Authors Nishiyama M.
  Title [Novel lysine biosynthesis: a key to elucidate evolution of metabolic and biosynthetic pathways]
  Journal Tanpakushitsu Kakusan Koso 49:758-63 (2004)
Reference   Authors Nishida H, Nishiyama M, Kobashi N, Kosuge T, Hoshino T, Yamane H.
  Title A prokaryotic gene cluster involved in synthesis of lysine through the amino adipate pathway: a key to the evolution of amino acid biosynthesis.
  Journal Reference   Authors Sakai H, Vassylyeva MN, Matsuura T, Sekine S, Gotoh K, Nishiyama M, Terada T, Shirouzu M, Kuramitsu S, Vassylyev DG, Yokoyama S.
  Title Crystal structure of a lysine biosynthesis enzyme, LysX, from Thermus thermophilus HB8.
  Journal Reference   Authors Hudson AO, Singh BK, Leustek T, Gilvarg C.
  Title An LL-diaminopimelate aminotransferase defines a novel variant of the lysine biosynthesis pathway in plants.
  Journal Reference   Authors Horie A, Tomita T, Saiki A, Kono H, Taka H, Mineki R, Fujimura T, Nishiyama C, Kuzuyama T, Nishiyama M
  Title Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus.
  Journal Reference   Authors Dairi T, Kuzuyama T, Nishiyama M, Fujii I
  Title Convergent strategies in biosynthesis.
  Journal Reference   Authors Gaston MA, Jiang R, Krzycki JA
  Title Functional context, biosynthesis, and genetic encoding of pyrrolysine.
  Journal Related mne00250   Alanine, aspartate and glutamate metabolism 
mne00260   Glycine, serine and threonine metabolism 
KO pathway