KEGG   PATHWAY: mye00630
Entry
mye00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Mycobacterium sp. EPa45
Class
Metabolism; Carbohydrate metabolism
Pathway map
mye00630  Glyoxylate and dicarboxylate metabolism
mye00630

Module
mye_M00621  Glycine cleavage system [PATH:mye00630]
mye_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:mye00630]
Other DBs
GO: 0046487 0043648
Organism
Mycobacterium sp. EPa45 [GN:mye]
Gene
AB431_17415  isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
AB431_03660  Isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
AB431_27035  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
AB431_24750  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
AB431_12220  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
AB431_16995  malate synthase [KO:K01638] [EC:2.3.3.9]
AB431_24545  hypothetical protein [KO:K01647] [EC:2.3.3.1]
AB431_13580  acnA; aconitate hydratase [KO:K27802] [EC:4.2.1.3 4.2.1.99]
AB431_22120  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AB431_24305  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AB431_21555  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AB431_21640  thiolase [KO:K00626] [EC:2.3.1.9]
AB431_16825  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AB431_24735  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AB431_06235  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AB431_26290  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AB431_01990  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AB431_25115  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AB431_24075  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AB431_26420  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AB431_26485  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AB431_24975  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
AB431_07365  transporter [KO:K00626] [EC:2.3.1.9]
AB431_22125  glyoxalase [KO:K05606] [EC:5.1.99.1]
AB431_07680  acetyl-COA carboxylase [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
AB431_07710  methylmalonyl-CoA carboxyltransferase [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
AB431_07705  hypothetical protein [KO:K27095]
AB431_19270  propionyl-CoA carboxylase subunit beta [KO:K18472] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
AB431_13650  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
AB431_13655  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
AB431_21885  methylmalonyl-CoA mutase [KO:K01849] [EC:5.4.99.2]
AB431_21890  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
AB431_21165  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
AB431_22810  FAD-linked oxidase [KO:K00104] [EC:1.1.99.14]
AB431_27355  catalase [KO:K03781] [EC:1.11.1.6]
AB431_12780  catalase [KO:K03781] [EC:1.11.1.6]
AB431_08425  catalase [KO:K03781] [EC:1.11.1.6]
AB431_19070  hypothetical protein [KO:K01091] [EC:3.1.3.18]
AB431_20090  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AB431_20455  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AB431_27410  glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
AB431_18945  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AB431_18980  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AB431_16700  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AB431_19545  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AB431_11065  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
AB431_06345  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
AB431_17010  glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
AB431_18885  glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
AB431_03635  dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
AB431_17035  glycine cleavage system protein H [KO:K02437]
AB431_20380  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
AB431_18845  hypothetical protein [KO:K00865] [EC:2.7.1.165]
AB431_22955  kgd; alpha-ketoglutarate decarboxylase [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
mye00010  Glycolysis / Gluconeogenesis
mye00020  Citrate cycle (TCA cycle)
mye00030  Pentose phosphate pathway
mye00053  Ascorbate and aldarate metabolism
mye00071  Fatty acid degradation
mye00230  Purine metabolism
mye00250  Alanine, aspartate and glutamate metabolism
mye00260  Glycine, serine and threonine metabolism
mye00620  Pyruvate metabolism
mye00710  Carbon fixation by Calvin cycle
mye00750  Vitamin B6 metabolism
mye00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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