KEGG   PATHWAY: ocy00230
Entry
ocy00230                    Pathway                                
Name
Purine metabolism - Tepiditoga spiralis
Class
Metabolism; Nucleotide metabolism
Pathway map
ocy00230  Purine metabolism
ocy00230

Module
ocy_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ocy00230]
ocy_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ocy00230]
ocy_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ocy00230]
ocy_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ocy00230]
Other DBs
GO: 0006163 0042278
Organism
Tepiditoga spiralis [GN:ocy]
Gene
OSSY52_05020  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
OSSY52_01260  pgm_1; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
OSSY52_15900  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
OSSY52_06160  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
OSSY52_13550  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
OSSY52_13820  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
OSSY52_13530  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
OSSY52_13560  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
OSSY52_13580  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
OSSY52_13570  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
OSSY52_13540  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
OSSY52_13600  N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
OSSY52_13590  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
OSSY52_17680  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
OSSY52_01210  purH_1; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
OSSY52_13830  purH_2; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
OSSY52_07030  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
OSSY52_01810  ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
OSSY52_00120  surE; 5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
OSSY52_14160  purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
OSSY52_22150  deoD_2; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
OSSY52_06290  deoD_1; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
OSSY52_14680  laccase domain protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
OSSY52_14150  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
OSSY52_15000  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
OSSY52_17870  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
OSSY52_12340  non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
OSSY52_01400  xdhB2; xanthine dehydrogenase FAD-binding subunit XdhB [KO:K13479] [EC:1.17.1.4]
OSSY52_14710  guaA; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
OSSY52_14760  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
OSSY52_02320  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
OSSY52_12700  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
OSSY52_09050  ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
OSSY52_18710  nrdD; anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
OSSY52_13970  hypothetical protein [KO:K15518] [EC:2.7.1.113]
OSSY52_15170  (p)ppGpp synthetase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
OSSY52_17640  hypothetical protein [KO:K07816] [EC:2.7.6.5]
OSSY52_15260  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
OSSY52_17670  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
OSSY52_19410  hypothetical protein [KO:K01241] [EC:3.2.2.4]
OSSY52_09440  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
OSSY52_08650  cpdC; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
OSSY52_10580  adenylate kinase [KO:K00939] [EC:2.7.4.3]
OSSY52_11460  mazG; nucleoside triphosphate pyrophosphohydrolase/pyrophosphatase MazG [KO:K04765] [EC:3.6.1.9]
OSSY52_04330  yqeA; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ocy00030  Pentose phosphate pathway
ocy00220  Arginine biosynthesis
ocy00250  Alanine, aspartate and glutamate metabolism
ocy00260  Glycine, serine and threonine metabolism
ocy00340  Histidine metabolism
ocy00630  Glyoxylate and dicarboxylate metabolism
ocy00730  Thiamine metabolism
ocy00740  Riboflavin metabolism
ocy00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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