KEGG   PATHWAY: panu00053
Entry
panu00053                   Pathway                                
Name
Ascorbate and aldarate metabolism - Papio anubis (olive baboon)
Class
Metabolism; Carbohydrate metabolism
Pathway map
panu00053  Ascorbate and aldarate metabolism
panu00053

Other DBs
GO: 0019852 0019577 0019572
Organism
Papio anubis (olive baboon) [GN:panu]
Gene
100126698  UGT1A4; UDP-glucuronosyltransferase 1-4 precursor [KO:K00699] [EC:2.4.1.17]
100126700  UGT1A5A; UDP glycosyl transferase 1A5A precursor [KO:K00699] [EC:2.4.1.17]
100126701  UGT1A1; UDP-glucuronosyltransferase 1-1 precursor [KO:K00699] [EC:2.4.1.17]
100126702  UGT1A6; UDP-glucuronosyltransferase 1-6 [KO:K00699] [EC:2.4.1.17]
100126703  UGT1A9; UDP-glucuronosyltransferase 1-9 precursor [KO:K00699] [EC:2.4.1.17]
100126705  UGT1A7; UDP-glucuronosyltransferase 1-7 precursor [KO:K00699] [EC:2.4.1.17]
100126761  UGT1A5B; UDP glycosyl transferase 1A5B precursor [KO:K00699] [EC:2.4.1.17]
100126762  UGT1A10B; UDP glycosyl transferase 1A10B precursor [KO:K00699] [EC:2.4.1.17]
100337517  UGT2B39; UDP-glucuronosyltransferase 2B39 precursor [KO:K00699] [EC:2.4.1.17]
100337521  UGT2B42; UDP-glucuronosyltransferase 2B42 precursor [KO:K00699] [EC:2.4.1.17]
100337522  UGT2B15; UDP-glucuronosyltransferase 2B15 precursor [KO:K00699] [EC:2.4.1.17]
100337523  UGT2B44; UDP-glucuronosyltransferase 2B44 precursor [KO:K00699] [EC:2.4.1.17]
100337524  UGT2B45; UDP-glucuronosyltransferase 2B45 precursor [KO:K00699] [EC:2.4.1.17]
100998352  ALDH1B1; aldehyde dehydrogenase X, mitochondrial [KO:K00128] [EC:1.2.1.3]
101000426  AKR1A1; aldo-keto reductase family 1 member A1 isoform X1 [KO:K00002] [EC:1.1.1.2]
101000694  ALDH3A2; aldehyde dehydrogenase family 3 member A2 isoform X1 [KO:K00128] [EC:1.2.1.3]
101004829  MIOX; inositol oxygenase [KO:K00469] [EC:1.13.99.1]
101005241  UGDH; UDP-glucose 6-dehydrogenase [KO:K00012] [EC:1.1.1.22]
101006382  GUSB; beta-glucuronidase [KO:K01195] [EC:3.2.1.31]
101007395  [KO:K01195] [EC:3.2.1.31]
101010645  [KO:K00699] [EC:2.4.1.17]
101014168  RGN; regucalcin [KO:K01053] [EC:3.1.1.17]
101016128  [KO:K00149] [EC:1.2.1.47 1.2.1.3]
101017012  [KO:K00699] [EC:2.4.1.17]
101019039  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
101019271  [KO:K00699] [EC:2.4.1.17]
101020325  UGT2A3; UDP-glucuronosyltransferase 2A3 [KO:K00699] [EC:2.4.1.17]
101023487  KL; klotho [KO:K14756] [EC:3.2.1.31]
116268495  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase isoform X1 [KO:K00149] [EC:1.2.1.47 1.2.1.3]
116268560  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
panu00020  Citrate cycle (TCA cycle)
panu00040  Pentose and glucuronate interconversions
panu00051  Fructose and mannose metabolism
panu00520  Amino sugar and nucleotide sugar metabolism
panu00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   

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