KEGG   PATHWAY: amaz00630
Entry
amaz00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Actinomadura madurae
Class
Metabolism; Carbohydrate metabolism
Pathway map
amaz00630  Glyoxylate and dicarboxylate metabolism
amaz00630

Module
amaz_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:amaz00630]
Other DBs
GO: 0046487 0043648
Organism
Actinomadura madurae [GN:amaz]
Gene
LUW76_00905  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
LUW76_25775  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
LUW76_28580  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
LUW76_40450  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
LUW76_18990  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
LUW76_47315  citrate synthase [KO:K01647] [EC:2.3.3.1]
LUW76_07400  hypothetical protein [KO:K01647] [EC:2.3.3.1]
LUW76_32700  citrate synthase 2 [KO:K01647] [EC:2.3.3.1]
LUW76_38150  steroid 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
LUW76_45225  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
LUW76_47015  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LUW76_05870  thiolase family protein [KO:K00626] [EC:2.3.1.9]
LUW76_06080  thiolase family protein [KO:K00626] [EC:2.3.1.9]
LUW76_06230  thiolase family protein [KO:K00626] [EC:2.3.1.9]
LUW76_16640  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LUW76_17505  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
LUW76_20490  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
LUW76_32755  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LUW76_35085  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
LUW76_35080  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
LUW76_18650  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
LUW76_18550  acyl-CoA carboxylase subunit beta [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
LUW76_18555  acyl-CoA carboxylase subunit epsilon [KO:K27095]
LUW76_00740  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
LUW76_40445  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
LUW76_43330  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
LUW76_46155  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
LUW76_24370  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
LUW76_40440  FAD-binding oxidoreductase [KO:K11472] [EC:1.1.99.14]
LUW76_40435  4Fe-4S dicluster domain-containing protein [KO:K11473] [EC:1.1.99.14]
LUW76_29320  HAD family phosphatase [KO:K01091] [EC:3.1.3.18]
LUW76_32615  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
LUW76_11465  form I ribulose bisphosphate carboxylase large subunit [KO:K01601] [EC:4.1.1.39]
LUW76_11460  ribulose bisphosphate carboxylase small subunit [KO:K01602] [EC:4.1.1.39]
LUW76_41410  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
LUW76_41445  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
LUW76_45155  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
LUW76_05245  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
LUW76_07645  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
LUW76_11385  glutamine synthetase beta-grasp domain-containing protein [KO:K01915] [EC:6.3.1.2]
LUW76_04460  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
LUW76_35425  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
LUW76_35435  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
LUW76_41490  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
LUW76_35790  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
LUW76_35430  gcvH; glycine cleavage system protein GcvH [KO:K02437]
LUW76_38245  TIM barrel protein [KO:K01816] [EC:5.3.1.22]
LUW76_41215  glycerate kinase [KO:K00865] [EC:2.7.1.165]
LUW76_22325  fumarate hydratase [KO:K03779] [EC:4.2.1.32]
LUW76_22330  fumarate hydratase C-terminal domain-containing protein [KO:K03780] [EC:4.2.1.32]
LUW76_44285  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
LUW76_10470  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
LUW76_13940  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
LUW76_20925  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
LUW76_37955  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
LUW76_13175  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
LUW76_07015  4Fe-4S dicluster domain-containing protein [KO:K00124]
LUW76_47865  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
LUW76_35315  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
amaz00010  Glycolysis / Gluconeogenesis
amaz00020  Citrate cycle (TCA cycle)
amaz00030  Pentose phosphate pathway
amaz00053  Ascorbate and aldarate metabolism
amaz00071  Fatty acid degradation
amaz00230  Purine metabolism
amaz00250  Alanine, aspartate and glutamate metabolism
amaz00260  Glycine, serine and threonine metabolism
amaz00620  Pyruvate metabolism
amaz00710  Carbon fixation by Calvin cycle
amaz00750  Vitamin B6 metabolism
amaz00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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