KEGG   PATHWAY: aof00061
Entry
aof00061                    Pathway                                
Name
Fatty acid biosynthesis - Asparagus officinalis (garden asparagus)
Class
Metabolism; Lipid metabolism
Pathway map
aof00061  Fatty acid biosynthesis
aof00061

Module
aof_M00082  Fatty acid biosynthesis, initiation [PATH:aof00061]
aof_M00083  Fatty acid biosynthesis, elongation [PATH:aof00061]
aof_M00086  beta-Oxidation, acyl-CoA synthesis [PATH:aof00061]
Other DBs
GO: 0006633
Organism
Asparagus officinalis (garden asparagus) [GN:aof]
Gene
109851050  acetyl-CoA carboxylase 1-like [KO:K11262] [EC:6.4.1.2 6.3.4.14 2.1.3.15]
109851035  acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, chloroplastic [KO:K01962] [EC:6.4.1.2 2.1.3.15]
109846884  acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, chloroplastic-like [KO:K01962] [EC:6.4.1.2 2.1.3.15]
109849819  biotin carboxyl carrier protein of acetyl-CoA carboxylase 1, chloroplastic-like [KO:K02160]
109821223  biotin carboxyl carrier protein of acetyl-CoA carboxylase 1, chloroplastic-like [KO:K02160]
109820668  biotin carboxylase 1, chloroplastic [KO:K01961] [EC:6.4.1.2 6.3.4.14]
109844771  biotin carboxylase 1, chloroplastic-like [KO:K01961] [EC:6.4.1.2 6.3.4.14]
109823134  uncharacterized protein LOC109823134 [KO:K01963] [EC:6.4.1.2 2.1.3.15]
CCL56_pgp062  accD; acetyl-CoA carboxylase beta subunit [KO:K01963] [EC:6.4.1.2 2.1.3.15]
109848382  malonate--CoA ligase isoform X1 [KO:K18660] [EC:6.2.1.76 6.2.1.-]
109842658  uncharacterized protein LOC109842658 [KO:K00645] [EC:2.3.1.39]
109841053  3-oxoacyl-[acyl-carrier-protein] synthase III, chloroplastic-like isoform X1 [KO:K00648] [EC:2.3.1.180]
109846072  3-oxoacyl-[acyl-carrier-protein] synthase III, chloroplastic-like [KO:K00648] [EC:2.3.1.180]
109840916  3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial isoform X1 [KO:K09458] [EC:2.3.1.179]
109833645  3-oxoacyl-[acyl-carrier-protein] synthase II, chloroplastic-like isoform X1 [KO:K09458] [EC:2.3.1.179]
109825671  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
109841761  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
109848577  3-oxoacyl-[acyl-carrier-protein] synthase II, chloroplastic-like isoform X1 [KO:K09458] [EC:2.3.1.179]
109844867  3-oxoacyl-[acyl-carrier-protein] synthase II, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
109844868  3-oxoacyl-[acyl-carrier-protein] synthase II, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
109840092  LOW QUALITY PROTEIN: 3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
109823339  LOW QUALITY PROTEIN: 3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
109846863  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic [KO:K09458] [EC:2.3.1.179]
109849048  3-oxoacyl-[acyl-carrier-protein] synthase II, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
109832956  short-chain type dehydrogenase/reductase-like [KO:K00059] [EC:1.1.1.100]
109832958  short-chain type dehydrogenase/reductase-like [KO:K00059] [EC:1.1.1.100]
109831668  3-oxoacyl-[acyl-carrier-protein] reductase 4-like [KO:K00059] [EC:1.1.1.100]
109832075  short-chain type dehydrogenase/reductase-like [KO:K00059] [EC:1.1.1.100]
109832076  short-chain type dehydrogenase/reductase-like [KO:K00059] [EC:1.1.1.100]
109832077  short-chain type dehydrogenase/reductase-like [KO:K00059] [EC:1.1.1.100]
109820513  3-oxoacyl-[acyl-carrier-protein] reductase 4-like [KO:K00059] [EC:1.1.1.100]
109823766  uncharacterized protein LOC109823766 [KO:K02372] [EC:4.2.1.59]
109831548  enoyl-[acyl-carrier-protein] reductase [NADH] 1, chloroplastic-like [KO:K00208] [EC:1.3.1.9 1.3.1.10]
109846388  enoyl-[acyl-carrier-protein] reductase [NADH] 1, chloroplastic-like isoform X1 [KO:K00208] [EC:1.3.1.9 1.3.1.10]
109835310  enoyl-[acyl-carrier-protein] reductase [NADH] 1, chloroplastic-like [KO:K00208] [EC:1.3.1.9 1.3.1.10]
109829950  probable trans-2-enoyl-CoA reductase, mitochondrial [KO:K07512] [EC:1.3.1.- 1.3.1.38]
109825405  palmitoyl-acyl carrier protein thioesterase, chloroplastic-like [KO:K10781] [EC:3.1.2.14 3.1.2.21]
109826182  palmitoyl-acyl carrier protein thioesterase, chloroplastic-like [KO:K10781] [EC:3.1.2.14 3.1.2.21]
109835670  palmitoyl-acyl carrier protein thioesterase, chloroplastic-like [KO:K10781] [EC:3.1.2.14 3.1.2.21]
109844902  palmitoyl-acyl carrier protein thioesterase, chloroplastic-like isoform X1 [KO:K10781] [EC:3.1.2.14 3.1.2.21]
109822131  palmitoyl-acyl carrier protein thioesterase, chloroplastic-like [KO:K10781] [EC:3.1.2.14 3.1.2.21]
109826150  oleoyl-acyl carrier protein thioesterase, chloroplastic-like isoform X1 [KO:K10782] [EC:3.1.2.14]
109837225  oleoyl-acyl carrier protein thioesterase 1, chloroplastic-like [KO:K10782] [EC:3.1.2.14]
109823800  stearoyl-[acyl-carrier-protein] 9-desaturase 5, chloroplastic-like [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109826287  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic-like [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109839625  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic-like [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109837217  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic-like isoform X1 [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
109823746  long chain acyl-CoA synthetase 9, chloroplastic [KO:K01897] [EC:6.2.1.3]
109840749  long chain acyl-CoA synthetase 4-like [KO:K01897] [EC:6.2.1.3]
109828250  LOW QUALITY PROTEIN: long chain acyl-CoA synthetase 9, chloroplastic-like [KO:K01897] [EC:6.2.1.3]
109828867  long chain acyl-CoA synthetase 4-like [KO:K01897] [EC:6.2.1.3]
109831595  long chain acyl-CoA synthetase 6, peroxisomal-like [KO:K01897] [EC:6.2.1.3]
109849798  LOW QUALITY PROTEIN: long chain acyl-CoA synthetase 1-like [KO:K01897] [EC:6.2.1.3]
109819633  long chain acyl-CoA synthetase 2 [KO:K01897] [EC:6.2.1.3]
109843489  long chain acyl-CoA synthetase 8 [KO:K01897] [EC:6.2.1.3]
109838878  probable acyl-activating enzyme 16, chloroplastic [KO:K01897] [EC:6.2.1.3]
109843171  long chain acyl-CoA synthetase 1-like [KO:K01897] [EC:6.2.1.3]
Compound
C00024  Acetyl-CoA
C00083  Malonyl-CoA
C00154  Palmitoyl-CoA
C00173  Acyl-[acyl-carrier protein]
C00229  Acyl-carrier protein
C00249  Hexadecanoic acid
C00383  Malonate
C00638  Long-chain fatty acid
C00685  3-Oxoacyl-[acyl-carrier protein]
C00693  trans-2,3-Dehydroacyl-[acyl-carrier protein]
C00712  (9Z)-Octadecenoic acid
C01203  Oleoyl-[acyl-carrier protein]
C01209  Malonyl-[acyl-carrier protein]
C01271  (3R)-3-Hydroxyacyl-[acyl-carrier protein]
C01530  Octadecanoic acid
C01571  Decanoic acid
C02679  Dodecanoic acid
C02843  Long-chain acyl-CoA
C03939  Acetyl-[acyl-carrier protein]
C04088  Octadecanoyl-[acyl-carrier protein]
C04180  cis-Dec-3-enoyl-[acp]
C04246  But-2-enoyl-[acyl-carrier protein]
C04618  (3R)-3-Hydroxybutanoyl-[acyl-carrier protein]
C04619  (3R)-3-Hydroxydecanoyl-[acyl-carrier protein]
C04620  (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein]
C04633  (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]
C04688  (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
C05223  Dodecanoyl-[acyl-carrier protein]
C05744  Acetoacetyl-[acp]
C05745  Butyryl-[acp]
C05746  3-Oxohexanoyl-[acp]
C05747  (3R)-3-Hydroxyhexanoyl-[acyl-carrier protein]
C05748  trans-Hex-2-enoyl-[acp]
C05749  Hexanoyl-[acp]
C05750  3-Oxooctanoyl-[acp]
C05751  trans-Oct-2-enoyl-[acp]
C05752  Octanoyl-[acp]
C05753  3-Oxodecanoyl-[acp]
C05754  trans-Dec-2-enoyl-[acp]
C05755  Decanoyl-[acp]
C05756  3-Oxododecanoyl-[acp]
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05758  trans-Dodec-2-enoyl-[acp]
C05759  3-Oxotetradecanoyl-[acp]
C05760  trans-Tetradec-2-enoyl-[acp]
C05761  Tetradecanoyl-[acp]
C05762  3-Oxohexadecanoyl-[acp]
C05763  trans-Hexadec-2-enoyl-[acp]
C05764  Hexadecanoyl-[acp]
C06423  Octanoic acid
C06424  Tetradecanoic acid
C08362  (9Z)-Hexadecenoic acid
C16219  3-Oxostearoyl-[acp]
C16220  (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein]
C16221  (2E)-Octadecenoyl-[acp]
C16520  Hexadecenoyl-[acyl-carrier protein]
C20683  Long-chain acyl-[acyl-carrier protein]
C20794  n-7 Unsaturated acyl-[acyl-carrier protein]
Reference
PMID:12061798
  Authors
Salas JJ, Ohlrogge JB.
  Title
Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases.
  Journal
Arch Biochem Biophys 403:25-34 (2002)
DOI:10.1016/S0003-9861(02)00017-6
Reference
PMID:12518017
  Authors
Zhang YM, Marrakchi H, White SW, Rock CO.
  Title
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.
  Journal
J Lipid Res 44:1-10 (2003)
DOI:10.1194/jlr.R200016-JLR200
Reference
PMID:11337402
  Authors
Voelker T, Kinney AJ.
  Title
VARIATIONS IN THE BIOSYNTHESIS OF SEED-STORAGE LIPIDS.
  Journal
Annu Rev Plant Physiol Plant Mol Biol 52:335-361 (2001)
DOI:10.1146/annurev.arplant.52.1.335
Reference
PMID:17573542
  Authors
Barker GC, Larson TR, Graham IA, Lynn JR, King GJ.
  Title
Novel insights into seed fatty acid synthesis and modification pathways from genetic diversity and quantitative trait Loci analysis of the Brassica C genome.
  Journal
Plant Physiol 144:1827-42 (2007)
DOI:10.1104/pp.107.096172
Reference
PMID:30201289
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Reference
PMID:25203508
  Authors
Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z
  Title
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.
  Journal
Nat Commun 5:4805 (2014)
DOI:10.1038/ncomms5805
Reference
PMID:19686777
  Authors
Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK, Kastaniotis AJ
  Title
Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.
  Journal
Prog Lipid Res 49:27-45 (2010)
DOI:10.1016/j.plipres.2009.08.001
Reference
PMID:27553474
  Authors
Kastaniotis AJ, Autio KJ, Keratar JM, Monteuuis G, Makela AM, Nair RR, Pietikainen LP, Shvetsova A, Chen Z, Hiltunen JK
  Title
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
  Journal
Biochim Biophys Acta Mol Cell Biol Lipids 1862:39-48 (2017)
DOI:10.1016/j.bbalip.2016.08.011
Related
pathway
aof00020  Citrate cycle (TCA cycle)
aof00062  Fatty acid elongation
aof00071  Fatty acid degradation
aof00410  beta-Alanine metabolism
aof00561  Glycerolipid metabolism
aof00564  Glycerophospholipid metabolism
aof00620  Pyruvate metabolism
aof00785  Lipoic acid metabolism
KO pathway
ko00061   
LinkDB

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